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XB-LAB-582

NXR: National Xenopus Resource

Xenopus Stock Center, USA

MBL, Woods Hole, MA

www.mbl.edu/xenopus/

People

Horb, Marko E. (Principal Investigator/Director)
Pearl, Esther (Research Associate/Assistant)

Research Area

The National Xenopus Resource (NXR) is located at the Marine Biological Laboratory (MBL) in Woods Hole, Massachusetts, and serves as a national stock center for X. laevis and X. tropicalis as well as a training center for advanced technologies (e.g. husbandry, cell biology, imaging, genetics, transgenesis, genomics). The NXR is funded by an award from the National Institute of Health, Office of the Director, Office of Research Infrastructure Programs (ORIP) and from the Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD). The MBL is an international center for research, education, and training in biology, biomedicine, and ecology. Housed in the MBL’s Loeb Laboratory, the National Xenopus Resource is a cornerstone of the Eugene Bell Center for Regenerative Biology and Tissue Engineering. The NXR provides a facility for breeding X. laevis and X. tropicalis, maintaining genetic stocks, providing stocks to researchers, developing new experimental tools and husbandry techniques, and meeting other needs of the Xenopus research community through workshops and meetings. Input from the Xenopus research community regarding what genetic lines should be raised, and priorities for advanced research courses, is highly encouraged. Please send feedback to Xenopus@mbl.edu.

Additional Information

The NXR breeds, maintains and distributes community generated transgenic lines. The NXR creates custom transgenic lines for individual investigators on a made-to- order basis. The NXR creates custom knockout lines in X. tropicalis or X. laevis using either TALEN or CRISPR/Cas The NXR Research Hotel offers a fee-based service for visiting scientists. The weekly fee provides researchers with a lab bench and use of equipment, chemicals and frogs. The NXR also rents tank space and provides animal feeding and general care services to affliated scientists

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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556