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XB-LAB-607

Sater Lab

cell fate and spatial patterning in vertebrates

University of Houston

Division of Cellular and Molecular Biology
Department of Biology and Biochemistry
University of Houston
Houston, TX77204-5001
USA

www.bchs.uh.edu/people/detail/?155622-961-5=asater

General/Lab Phone: (713) 743-2688

People

Sater, Amy K. (Principal Investigator/Director)

Research Area

I am interested in the establishment of cell fate and spatial pattern in vertebrate embryos. Embryonic cells must integrate information from a diverse array of extracellular signals in order to make developmental decisions. For example, ectoderm cells choose between neural and epidermal fates in response to several growth factors, including Bone Morphogenetic Protein-4 (BMP4), which induces epidermis, as well as Fibroblast Growth Factors (FGFs) and Insulin-like Growth Factor (IGF), which have been implicated in the specification of neural fate. Studies in my lab investigate signaling pathway interactions and transcriptional regulation in the establishment of ectodermal fate and anteroposterior pattern in Xenopus embryos.

Additional Information

Current Projects 1) Interactions between FGF and BMP signaling pathways 2) Role of ashwin in the establishment of anteroposterior pattern 3) A genetic map for Xenopus tropicalis

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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556