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XB-LAB-628

Davidson Laboratory

Research Interests

Morphogenesis and Developmental Biomechanics

Research Area

Cells and tissues are shaped by mechanical forces early during development to produce the basic body plan and establish functional organs. Our group combines experimental and theoretical approaches to reverse-engineer these mechanical inherently mechanical processes. Our experimental methods include classical embryological, modern cell biological ones combined with new synthetic systems biology methods.

Current Members

Davidson, Lance A. (Principal Investigator/Director)

Alumni


Additional Information

Projects: Cytoskeletal control and physical mechanics of convergent extension and axis elongation. Cell and tissue mechanics of mesenchymal sheet migration, spreading, and engulfment. Molecular and mechanical mechanisms that control cell contraction. The regulation of cell polarity and tissue movements that shape the heart forming region.

Contact

Institution: University of Pittsburgh

Address:
Dept. Bioengineering
Swanson School of Engineering
University of Pittsburgh
Pittsburgh, PA
15213, USA

Web Page: www.engr2.pitt.edu/ldavidson/

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