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Profile Publications(21)
XB-PERS-1689


Peter L. Jones

Position

Principal Scientist

Research Description

We are investigating the molecular mechanisms leading to facioscapulohumeral muscular dystrophy (FSHD) pathology.  FSHD, the most prevalent muscular dystrophy afflicting children and adults, is caused by a dominant deletion in a macrosatellite repeat array at chromosome 4q35 leading to an epigenetic dysregulation of gene expression.  We are using the early development of Xenopus laevis to 1) test the effect of mis-expression of FSHD candidate genes on the development of the vertebrate musculature and vasculature and 2) determine the normal developmental role of FSHD candidate genes.


Contact

Address:
Program in Regenerative Biology
Boston Biomedical Research Institute
64 Grove St
Watertown, MA
02472, USA

Email: pjones@bbri.org

Web Page: http://www.bbri.org/index.php/our_scientists/articles/peter-l-jones-phd.html

General/Lab Fax:  617-658-7789
Phone:  617-658-7745


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