Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Profile Publications(8)

James M. Wells

Research Description

We study the molecular mechanisms underlying endoderm organ development in mouse and chick. Why study endoderm development? The genes and signaling mechanisms that we identify in our embryonic studies are being used to promote the differentiation of embryonic and adult stem cells into therapeutically important cell types such as insulin producing beta cells. Stem cells are a promising renewable source of cells for transplantation to treat human diseases like Type 1 diabetes.

Lab Memberships

Wells Lab (Principal Investigator/Director)


Cincinnati Children's Hospital Medical Center
3333 Burnet Avenue
Cincinnati, Ohio
45229-3039, USA


Phone:  513-636-8767

Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556