James M. Wells
We study the molecular mechanisms underlying endoderm organ development in mouse and chick. Why study endoderm development? The genes and signaling mechanisms that we identify in our embryonic studies are being used to promote the differentiation of embryonic and adult stem cells into therapeutically important cell types such as insulin producing beta cells. Stem cells are a promising renewable source of cells for transplantation to treat human diseases like Type 1 diabetes.
Cincinnati Children's Hospital Medical Center
3333 Burnet Avenue