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Profile Publications(2)
XB-PERS-1851

Simon M. Hughes

Professor of Developmental Cell Biology

Randell Divison of Cell and Molecular Biophysics
New Hunt's House
Guy's Campus
King's College London
London
SE1 1UL, United Kingdom

simon.hughes@kcl.ac.uk
www.kcl.ac.uk/biohealth/research/divisions/randall/sections/signalling/hughes/index.aspx

Phone:  020 7848 6434
Fax:  020 7848 6435

Research Description

We work on zebrafish (mainly), Xenopus, chick and mouse muscle development. We have interest in training, aging, and muscle diseases that impact on people. We want to understand the patterning, growth, adaptation and repair of skeletal muscle. We have identified molecular pathways regulating the patterning of muscle tissue in the embryo and influencing muscle adaptation in the adult. Recent work has revealed new steps in myogenesis, which we are pursuing by in vivo imaging in zebrafish and molecular genetics in amniotes: we aim to understand the cell biology of development in vivo.

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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556