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Profile Publications(114)

Nathan Dascal

Professor of Cellular/Molecular Neurophysiology

Departments of Physiology and Pharmacology
Sackler Faculty of Medicine
Tel Aviv University
Tel Aviv
69978, Israel

Phone:  03-6405743

Research Description

Research topics: understanding of molecular mechanisms of signal transduction by neurotransmitters in neurons, and their relation to cell function and to human disease.

Research methods: Electrophysiology, Protein Biochemistry, Fluorescence Resonance Energy Transfer (FRET), Molecular biology, Mathematical and Kinetic Modeling and Simulation, Immunocytochemistry

Main projects in the lab include:

Molecular mechanisms of function and regulation of G protein activated K+ channels (GIRK) and neuronal Ca2+ channels (Cav2) in health and disease
The diverse coupling of G protein-coupled receptors with G proteins and effectors in heterologous expression systems and in nerve cells
Regulation of ion channels by drugs used in treatment of neurological disorders

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