The musculoskeletal system is a highly interdependent functional unit in which each component is irreplaceable. In our group we analyze the development and regeneration of the musculoskeletal system. We are specifically interested in understanding the mechanisms governing the specification of mesenchymal tissue types, especially muscle, connective tissue and cartilage during vertebrate limb development. Furthermore we are interested in the interaction of the different mesenchymal lineages during development of the musculoskeletal system and its aberration in disease. As regenerative processes in many instances are recapitulations of developmental processes, our goal is to transfer our understanding of developmental mechanisms to regenerative situations in order to - in the long run - improve these processes.
Lab MembershipsStricker Group (Principal Investigator/Director)
Development and Disease Group
Max-Planck-Institute for Molecular Genetics