Richard M. Harland
The objective of our work is to understand early vertebrate development at the molecular level. We study this problem in both the amphibian Xenopus, and in the mouse. Xenopus embryos are large and easily manipulated, so that the function of various macromolecules, such as RNA and protein, can be assayed by microinjection into living embryos. Functional assays in Xenopus can then be complemented by genetic knockouts in the mouse, to gain fuller understanding of the normal requirements for gene action in the developing embryo.
Lab MembershipsHarland Lab (Principal Investigator/Director)
Department of Molecular & Cell Biology
University of California, Berkeley
Life Sciences Addition #3200
General/Lab Fax: 5106436791