Rebecca S. Hartley
Associate Professor of Cell Biology and PhysiologyThe University of New Mexico
Albuquerque, New Mexico
319 335 7501
Fax: 319 335 7198
Post-transcriptional mechanisms of cell cycle regulation in the early embryo. The goal of our laboratory is to define post-transcriptional mechanisms of cell cycle regulation in the early embryonic cell cycle of Xenopus laevis and in the cancer cell cycle. We study RNA binding proteins and microRNAs, post-transcriptional regulators responsible for regulating the early embryonic cell cycle, and whose expression is disrupted in cancer. Specifically, we are assessing the role of Human antigen R (HuR), cold-inducible RNA binding protein (CIRP) and microRNAs in co-reulating targets implicated in breast cancer etiology.