Our focus is on blood and the cardiovascular system. We have a particular interest in the programming of blood stem cells, an understanding of which will inform our understanding of many diseases including leukaemias. For example, genetic and environmental insults can be modelled and both the consequences and actions that might induce recovery can be predicted. In addition, realising the potential of stem cells to repair damaged or lost tissue will depend on the ability to manipulate these cells which in turn will benefit from a better understanding of these molecular circuitries.
Lab MembershipsPatient Lab (Principal Investigator/Director)
British Xenopus Group (Other)
The Weatherall Institute of Molecular Medicine
University of Oxford
John Radcliffe Hospital
OX3 9DS, United Kingdom