Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Profile Publications(39)
XB-PERS-1964

Monica Palmada

Professor


Monica.Palmada@uk-essen.de
www.uni-due.de/zmb/members/palmada/overview.shtml

Research Description

PI3-kinase signal transduction in diabetes and cancer; molecular mechanisms of cancer cell metastasis and radiation/chemotherapy resistance; tumor suppressor genes with emphasis on NHERF scaffold proteins; transgenic mouse models

Current studies in our lab focus on:

    -Identification of molecular signals targeting the activity and surface expression of insulin-sensitive glucose transport proteins (phosphorylation, ubiquitination, endosomal recycling)
    -Functional characterization and localization of facilitative glucose transporter GLUT12 in tumor cells
    -Role of nutrient (glucose) uptake in decreased sensitivity to radiation and chemotherapy: contribution of glucose transporters to radiation survival, glucose transporter expression levels as a predictive marker of radioresistance
    -Significance of NHERF/Akt/SGK interaction in cancer cell growth and metastasis
    -Generation of transgenic mouse model

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556