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Profile Publications(32)
XB-PERS-861

Carole LaBonne

Assistant Professor of Biochemistry/Molecular Biology/Cell Biology

Department of Molecular Biosciences
Northwestern University
Evanston, IL
60208, USA

clabonne@northwestern.edu
www.biochem.northwestern.edu/labonne/

General/Lab Phone:  847.467.4043
Phone:  847.491.4165
Fax:  847.491.4970

Research Description

My laboratory studies the cellular and molecular events underlying the formation, migration, and differentiation of neural crest cells. These multipotent stem cell-like embryonic precursor cells migrate extensively and initiate an amazingly diverse set of derivatives in vertebrate embryos. Neural crest cells are important precursors to the peripheral nervous system, and give rise to a wide variety of neuronal and glial cell types. In addition, neural crest cells form a number of important non-neuronal derivatives including melanocytes, craniofacial bone and cartilage, and smooth muscle. This remarkable diversity makes the neural crest an exciting system in which to investigate the mechanisms which cells use to make decisions about their fate.

Lab Memberships

LaBonne Lab (Principal Investigator/Director)

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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556