Xenbase v4.11 Release

Xenopus expression data from GEO available. Viewable on JBrowse.

X. laevis protein expression profiles on gene pages.

Dual cationic and anionic metabolite analysis in a single cell

Portero and Nemes published in Analyst their approach enabling dual sequential analysis of cationic and anionic metabolites. These were measured in the same identified cell from live vertebrate embryos.

Xenopus Resources and Emerging Technologies Meeting 2019

October 11-14, 2019 at the National Xenopus Resource Center, MBL, Woods Hole, MA, USA.

Genome Editing Workshop 2019

October 14-24, 2019

National Xenopus Research Center, MBL at Woods Hole, MA, USA.

SDB 78th Annual Meeting

SDB 78th Annual Meeting
Boston, Massachusetts
July 26-30, 2019

meeting website

Message from SDB President, Lila Solnica-Krezel, Ph.D. 

Xenopus ORFeome v2

Updated Xenopus ORFeome clones include:

~10,250 genes, ~7,700 with human orthologues in X. laevis
~3,970 genes, ~3,800 with human orthologues in X. tropicalis

Cell and Developmental Biology of Xenopus: 2019 Course at Cold Spring Harbor

April 3-16, 2019

This course is designed for those new to the Xenopus field, as well as for more advanced students who are interested in emerging technologies.

Application Deadline: January 31, 2019

Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring

Cagnetta et al. published in Molecular Cell Sema3A triggers the phosphorylation of eIF2α in axons through an initial wave of local protein synthesis. eIF2α phosphorylation upregulates global translation, via differential eIF2B activity, and is required for neural wiring.

Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome

Cagnetta et al. published in Neuron a highly sensitive proteomics approach characterizing the nascent proteome of axons on a rapid timescale. Different extrinsic cues trigger distinct signatures of up-/down-regulated nascent protein changes within 5 minutes. 

Mechanical properties during convergent extension

Shawky et al. published in Development demonstrating cortical F-actin density and composition contribute to mechanical cellular properties of convergent extension during embryogenesis.

2nd European Amphibian Conference

Second European Amphibian Club conference to be held 26th-29th June 2019, in Lutherstadt-Wittenberg, Germany.
Abstract deadline: April 15, 2019.

Xenbase v4.11 Release

Xenopus expression data from GEO available. Viewable on JBrowse.

X. laevis protein expression profiles on gene pages.