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Summary Expression Phenotypes Gene Literature (198) GO Terms (2) Nucleotides (430) Proteins (122) Interactants (198) Wiki
XB--494199

Papers associated with grin1



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Ethanol inhibition of N-methyl-D-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue., Ronald KM, Mirshahi T, Woodward JJ., J Biol Chem. November 30, 2001; 276 (48): 44729-35.

Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as major site of conantokin-G inhibition., Wittekindt B, Malany S, Schemm R, Otvos L, Maccecchini ML, Laube B, Betz H., Neuropharmacology. November 1, 2001; 41 (6): 753-61.

Lead inhibition of NMDA channels in native and recombinant receptors., Gavazzo P, Gazzoli A, Mazzolini M, Marchetti C., Neuroreport. October 8, 2001; 12 (14): 3121-5.

Activation of metabotropic glutamate receptor 1 accelerates NMDA receptor trafficking., Lan JY, Skeberdis VA, Jover T, Zheng X, Bennett MV, Zukin RS., J Neurosci. August 15, 2001; 21 (16): 6058-68.

Subunit specificity and mechanism of action of NMDA partial agonist D-cycloserine., Sheinin A, Shavit S, Benveniste M., Neuropharmacology. August 1, 2001; 41 (2): 151-8.

High-affinity Zn block in recombinant N-methyl-D-aspartate receptors with cysteine substitutions at the Q/R/N site., Amar M, Perin-Dureau F, Neyton J., Biophys J. July 1, 2001; 81 (1): 107-16.

Identification of molecular determinants that are important in the assembly of N-methyl-D-aspartate receptors., Meddows E, Le Bourdelles B, Grimwood S, Wafford K, Sandhu S, Whiting P, McIlhinney RA., J Biol Chem. June 1, 2001; 276 (22): 18795-803.

The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801., Rammes G, Mahal B, Putzke J, Parsons C, Spielmanns P, Pestel E, Spanagel R, Zieglgänsberger W, Schadrack J., Neuropharmacology. May 1, 2001; 40 (6): 749-60.

Protein kinase C modulates NMDA receptor trafficking and gating., Lan JY, Skeberdis VA, Jover T, Grooms SY, Lin Y, Araneda RC, Zheng X, Bennett MV, Zukin RS., Nat Neurosci. April 1, 2001; 4 (4): 382-90.

Insulin promotes rapid delivery of N-methyl-D- aspartate receptors to the cell surface by exocytosis., Skeberdis VA, Lan J, Zheng X, Zukin RS, Bennett MV., Proc Natl Acad Sci U S A. March 13, 2001; 98 (6): 3561-6.

An N-methyl-D-aspartate receptor channel blocker with neuroprotective activity., Tai KK, Blondelle SE, Ostresh JM, Houghten RA, Montal M., Proc Natl Acad Sci U S A. March 13, 2001; 98 (6): 3519-24.

NMDA and glycine regulate the affinity of the Mg2+-block site in NR1-1a/NR2A NMDA receptor channels expressed in Xenopus oocytes., Liu Y, Hill RH, Arhem P, von Euler G., Life Sci. March 9, 2001; 68 (16): 1817-26.

K(+) occupancy of the N-methyl-d-aspartate receptor channel probed by Mg(2+) block., Zhu Y, Auerbach A., J Gen Physiol. March 1, 2001; 117 (3): 287-98.            

Na(+) occupancy and Mg(2+) block of the n-methyl-d-aspartate receptor channel., Zhu Y, Auerbach A., J Gen Physiol. March 1, 2001; 117 (3): 275-86.              

Three pairs of cysteine residues mediate both redox and zn2+ modulation of the nmda receptor., Choi Y, Chen HV, Lipton SA., J Neurosci. January 15, 2001; 21 (2): 392-400.

Effects of volatile solvents on recombinant N-methyl-D-aspartate receptors expressed in Xenopus oocytes., Cruz SL, Balster RL, Woodward JJ., Br J Pharmacol. December 1, 2000; 131 (7): 1303-8.

Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors., Low CM, Zheng F, Lyuboslavsky P, Traynelis SF., Proc Natl Acad Sci U S A. September 26, 2000; 97 (20): 11062-7.

Modulation of hypothalamic NMDA receptor function by cyclic AMP-dependent protein kinase and phosphatases., Nijholt I, Blank T, Liu A, Kügler H, Spiess J., J Neurochem. August 1, 2000; 75 (2): 749-54.

In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus., White HS, McCabe RT, Armstrong H, Donevan SD, Cruz LJ, Abogadie FC, Torres J, Rivier JE, Paarmann I, Hollmann M, Olivera BM., J Pharmacol Exp Ther. January 1, 2000; 292 (1): 425-32.

Protein kinase C potentiation of N-methyl-D-aspartate receptor activity is not mediated by phosphorylation of N-methyl-D-aspartate receptor subunits., Zheng X, Zhang L, Wang AP, Bennett MV, Zukin RS., Proc Natl Acad Sci U S A. December 21, 1999; 96 (26): 15262-7.

A mutation in the glycine binding pocket of the N-methyl-D-aspartate receptor NR1 subunit alters agonist efficacy., Wood MW, VanDongen HM, VanDongen AM., Brain Res Mol Brain Res. November 10, 1999; 73 (1-2): 189-92.

4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine: a novel, potent, and selective NR1/2B NMDA receptor antagonist., Zhou ZL, Cai SX, Whittemore ER, Konkoy CS, Espitia SA, Tran M, Rock DM, Coughenour LL, Hawkinson JE, Boxer PA, Bigge CF, Wise LD, Weber E, Woodward RM, Keana JF., J Med Chem. July 29, 1999; 42 (15): 2993-3000.

NMDA receptor subunit gene expression in the rat brain: a quantitative analysis of endogenous mRNA levels of NR1Com, NR2A, NR2B, NR2C, NR2D and NR3A., Goebel DJ, Poosch MS., Brain Res Mol Brain Res. June 8, 1999; 69 (2): 164-70.

A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D-aspartate receptor: effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein., Masuko T, Kashiwagi K, Kuno T, Nguyen ND, Pahk AJ, Fukuchi J, Igarashi K, Williams K., Mol Pharmacol. June 1, 1999; 55 (6): 957-69.

Investigation by ion channel domain transplantation of rat glutamate receptor subunits, orphan receptors and a putative NMDA receptor subunit., Villmann C, Strutz N, Morth T, Hollmann M., Eur J Neurosci. May 1, 1999; 11 (5): 1765-78.

Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action., Kleckner NW, Glazewski JC, Chen CC, Moscrip TD., J Pharmacol Exp Ther. May 1, 1999; 289 (2): 886-94.

NMDAR channel segments forming the extracellular vestibule inferred from the accessibility of substituted cysteines., Beck C, Wollmuth LP, Seeburg PH, Sakmann B, Kuner T., Neuron. March 1, 1999; 22 (3): 559-70.

Intracellular calcium enhances the ethanol sensitivity of NMDA receptors through an interaction with the C0 domain of the NR1 subunit., Mirshahi T, Anders DL, Ronald KM, Woodward JJ., J Neurochem. September 1, 1998; 71 (3): 1095-107.

Neurosteroid modulation of recombinant ionotropic glutamate receptors., Yaghoubi N, Malayev A, Russek SJ, Gibbs TT, Farb DH., Dev Biol. August 24, 1998; 803 (1-2): 153-60.

Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit., Traynelis SF, Burgess MF, Zheng F, Lyuboslavsky P, Powers JL., J Neurosci. August 15, 1998; 18 (16): 6163-75.

Differentiation of glycine antagonist sites of N-methyl-D-aspartate receptor subtypes. Preferential interaction of CGP 61594 with NR1/2B receptors., Honer M, Benke D, Laube B, Kuhse J, Heckendorn R, Allgeier H, Angst C, Monyer H, Seeburg PH, Betz H, Mohler H., J Biol Chem. May 1, 1998; 273 (18): 11158-63.

Selected peptides targeted to the NMDA receptor channel protect neurons from excitotoxic death., Ferrer-Montiel AV, Merino JM, Blondelle SE, Perez-Payà E, Houghten RA, Montal M., Nat Biotechnol. March 1, 1998; 16 (3): 286-91.

Internal Mg2+ block of recombinant NMDA channels mutated within the selectivity filter and expressed in Xenopus oocytes., Kupper J, Ascher P, Neyton J., J Physiol. February 15, 1998; 507 ( Pt 1) 1-12.

State-dependent NMDA receptor antagonism by Ro 8-4304, a novel NR2B selective, non-competitive, voltage-independent antagonist., Kew JN, Trube G, Kemp JA., Br J Pharmacol. February 1, 1998; 123 (3): 463-72.

Intracellular Mg2+ interacts with structural determinants of the narrow constriction contributed by the NR1-subunit in the NMDA receptor channel., Wollmuth LP, Kuner T, Sakmann B., J Physiol. January 1, 1998; 506 ( Pt 1) 33-52.

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+., Wollmuth LP, Kuner T, Sakmann B., J Physiol. January 1, 1998; 506 ( Pt 1) 13-32.

An active-site histidine of NR1/2C mediates voltage-independent inhibition by zinc., Gray AT, Leonoudakis DJ, Yost CS., Brain Res Mol Brain Res. December 1, 1997; 52 (1): 157-61.

Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids., Park-Chung M, Wu FS, Purdy RH, Malayev AA, Gibbs TT, Farb DH., Mol Pharmacol. December 1, 1997; 52 (6): 1113-23.

Ca2+ influx amplifies protein kinase C potentiation of recombinant NMDA receptors., Zheng X, Zhang L, Wang AP, Bennett MV, Zukin RS., J Neurosci. November 15, 1997; 17 (22): 8676-86.

Benzyl-polyamines: novel, potent N-methyl-D-aspartate receptor antagonists., Igarashi K, Shirahata A, Pahk AJ, Kashiwagi K, Williams K., J Pharmacol Exp Ther. November 1, 1997; 283 (2): 533-40.

Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns., Premkumar LS, Auerbach A., J Gen Physiol. November 1, 1997; 110 (5): 485-502.                        

Xenopus oocytes express a unitary glutamate receptor endogenously., Soloviev MM, Barnard EA., J Mol Biol. October 17, 1997; 273 (1): 14-8.

High-affinity zinc inhibition of NMDA NR1-NR2A receptors., Paoletti P, Ascher P, Neyton J., J Neurosci. August 1, 1997; 17 (15): 5711-25.

Control of NMDA receptor activation by a glycine transporter co-expressed in Xenopus oocytes., Supplisson S, Bergman C., J Neurosci. June 15, 1997; 17 (12): 4580-90.

N1-dansyl-spermine and N1-(n-octanesulfonyl)-spermine, novel glutamate receptor antagonists: block and permeation of N-methyl-D-aspartate receptors., Chao J, Seiler N, Renault J, Kashiwagi K, Masuko T, Igarashi K, Williams K., Mol Pharmacol. May 1, 1997; 51 (5): 861-71.

An alanine residue in the M3-M4 linker lines the glycine binding pocket of the N-methyl-D-aspartate receptor., Wood MW, VanDongen HM, VanDongen AM., J Biol Chem. February 7, 1997; 272 (6): 3532-7.

Subconductance states of a mutant NMDA receptor channel kinetics, calcium, and voltage dependence., Premkumar LS, Qin F, Auerbach A., J Gen Physiol. February 1, 1997; 109 (2): 181-9.      

NR1 and NR2 subunit contributions to N-methyl-D-aspartate receptor channel blocker pharmacology., Monaghan DT, Larsen H., J Pharmacol Exp Ther. February 1, 1997; 280 (2): 614-20.

Functional expression of a recombinant unitary glutamate receptor from Xenopus, which contains N-methyl-D-aspartate (NMDA) and non-NMDA receptor subunits., Soloviev MM, Brierley MJ, Shao ZY, Mellor IR, Volkova TM, Kamboj R, Ishimaru H, Sudan H, Harris J, Foldes RL, Grishin EV, Usherwood PN, Barnard EA., J Biol Chem. December 20, 1996; 271 (51): 32572-9.

Subtype-selective inhibition of N-methyl-D-aspartate receptors by haloperidol., Ilyin VI, Whittemore ER, Guastella J, Weber E, Woodward RM., Mol Pharmacol. December 1, 1996; 50 (6): 1541-50.

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