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Summary Expression Phenotypes Gene Literature (204) GO Terms (4) Nucleotides (291) Proteins (56) Interactants (824) Wiki
XB--1001989

Papers associated with cdk2



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The spindle checkpoint kinase bub1 and cyclin e/cdk2 both contribute to the establishment of meiotic metaphase arrest by cytostatic factor., Tunquist BJ, Schwab MS, Chen LG, Maller JL., Curr Biol. June 25, 2002; 12 (12): 1027-33.

Signalling pathways in oocyte meiotic maturation., Schmitt A, Nebreda AR., J Cell Sci. June 15, 2002; 115 (Pt 12): 2457-9.  

Screening for sequence-specific RNA-BPs by comprehensive UV crosslinking., Hartley R, Le Meuth-Metzinger V, Osborne HB., BMC Mol Biol. June 7, 2002; 3 8.      

Xic1 degradation in Xenopus egg extracts is coupled to initiation of DNA replication., You Z, Harvey K, Kong L, Newport J., Genes Dev. May 15, 2002; 16 (10): 1182-94.

Co-ordinating retinal histogenesis: early cell cycle exit enhances early cell fate determination in the Xenopus retina., Ohnuma S, Hopper S, Wang KC, Philpott A, Harris WA., Development. May 1, 2002; 129 (10): 2435-46.            

Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2., Porter LA, Dellinger RW, Tynan JA, Barnes EA, Kong M, Lenormand JL, Donoghue DJ., J Cell Biol. April 29, 2002; 157 (3): 357-66.                    

Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45., Wohlschlegel JA, Dhar SK, Prokhorova TA, Dutta A, Walter JC., Mol Cell. February 1, 2002; 9 (2): 233-40.

Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extracts., Matsumoto Y, Maller JL., Science. January 18, 2002; 295 (5554): 499-502.

A novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilization., Cau J, Faure S, Comps M, Delsert C, Morin N., J Cell Biol. December 10, 2001; 155 (6): 1029-42.                    

Xenopus phospho-CDK7/cyclin H expressed in baculoviral-infected insect cells., Lawrie AM, Tito P, Hernandez H, Brown NR, Robinson CV, Endicott JA, Noble ME, Johnson LN., Protein Expr Purif. November 1, 2001; 23 (2): 252-60.

Centrosome cohesion is regulated by a balance of kinase and phosphatase activities., Meraldi P, Nigg EA., J Cell Sci. October 1, 2001; 114 (Pt 20): 3749-57.

Differential regulation of Cdc2 and Cdk2 by RINGO and cyclins., Karaiskou A, Perez LH, Ferby I, Ozon R, Jessus C, Nebreda AR., J Biol Chem. September 21, 2001; 276 (38): 36028-34.

Role for cyclin-dependent kinase 2 in mitosis exit., D'Angiolella V, Costanzo V, Gottesman ME, Avvedimento EV, Gautier J, Grieco D., Curr Biol. August 7, 2001; 11 (15): 1221-6.

Triggering ubiquitination of a CDK inhibitor at origins of DNA replication., Furstenthal L, Swanson C, Kaiser BK, Eldridge AG, Jackson PK., Nat Cell Biol. August 1, 2001; 3 (8): 715-22.

Cyclin E morpholino delays embryogenesis in Xenopus., Audic Y, Boyle B, Slevin M, Hartley RS., Genesis. July 1, 2001; 30 (3): 107-9.  

The N-terminal helix of Xenopus cyclins A and B contributes to binding specificity of the cyclin-CDK complex., Goda T, Funakoshi M, Suhara H, Nishimoto T, Kobayashi H., J Biol Chem. May 4, 2001; 276 (18): 15415-22.

S and G2 phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells., Hu B, Mitra J, van den Heuvel S, Enders GH., Mol Cell Biol. April 1, 2001; 21 (8): 2755-66.

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication., Furstenthal L, Kaiser BK, Swanson C, Jackson PK., J Cell Biol. March 19, 2001; 152 (6): 1267-78.                    

Specificity of natural and artificial substrates for human Cdc25A., Rudolph J, Epstein DM, Parker L, Eckstein J., Anal Biochem. February 1, 2001; 289 (1): 43-51.

The midblastula transition in Xenopus embryos activates multiple pathways to prevent apoptosis in response to DNA damage., Finkielstein CV, Lewellyn AL, Maller JL., Proc Natl Acad Sci U S A. January 30, 2001; 98 (3): 1006-11.            

Regulation of nuclear transport and degradation of the Xenopus cyclin-dependent kinase inhibitor, p27Xic1., Chuang LC, Yew PR., J Biol Chem. January 12, 2001; 276 (2): 1610-7.

Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts., Walter JC., J Biol Chem. December 15, 2000; 275 (50): 39773-8.

Dual-specific Cdc25B phosphatase: in search of the catalytic acid., Chen W, Wilborn M, Rudolph J., Biochemistry. September 5, 2000; 39 (35): 10781-9.

Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage., Costanzo V, Robertson K, Ying CY, Kim E, Avvedimento E, Gottesman M, Grieco D, Gautier J., Mol Cell. September 1, 2000; 6 (3): 649-59.

Dissection of the XChk1 signaling pathway in Xenopus laevis embryos., Kappas NC, Savage P, Chen KC, Walls AT, Sible JC., Mol Biol Cell. September 1, 2000; 11 (9): 3101-8.

Nuclear accumulation of cyclin E/Cdk2 triggers a concentration-dependent switch for the destruction of p27Xic1., Swanson C, Ross J, Jackson PK., Proc Natl Acad Sci U S A. July 5, 2000; 97 (14): 7796-801.

Disruption of nuclear lamin organization blocks the elongation phase of DNA replication., Moir RD, Spann TP, Herrmann H, Goldman RD., J Cell Biol. June 12, 2000; 149 (6): 1179-92.                    

Chromatin-bound Cdc6 persists in S and G2 phases in human cells, while soluble Cdc6 is destroyed in a cyclin A-cdk2 dependent process., Coverley D, Pelizon C, Trewick S, Laskey RA., J Cell Sci. June 1, 2000; 113 ( Pt 11) 1929-38.

Distinct phosphoisoforms of the Xenopus Mcm4 protein regulate the function of the Mcm complex., Pereverzeva I, Whitmire E, Khan B, Coué M., Mol Cell Biol. May 1, 2000; 20 (10): 3667-76.

Interaction of Xenopus Cdc2 x cyclin A1 with the origin recognition complex., Romanowski P, Marr J, Madine MA, Rowles A, Blow JJ, Gautier J, Laskey RA., J Biol Chem. February 11, 2000; 275 (6): 4239-43.

Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis., Findeisen M, El-Denary M, Kapitza T, Graf R, Strausfeld U., Eur J Biochem. September 1, 1999; 264 (2): 415-26.

A maternal form of the phosphatase Cdc25A regulates early embryonic cell cycles in Xenopus laevis., Kim SH, Li C, Maller JL., Dev Biol. August 15, 1999; 212 (2): 381-91.            

Giant eyes in Xenopus laevis by overexpression of XOptx2., Zuber ME, Perron M, Philpott A, Bang A, Harris WA., Cell. August 6, 1999; 98 (3): 341-52.              

Characterization of a novel cdk1-related kinase., Détivaud L, Pettit GR, Meijer L., Eur J Biochem. August 1, 1999; 264 (1): 55-66.

A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts., Rosania GR, Merlie J, Gray N, Chang YT, Schultz PG, Heald R., Proc Natl Acad Sci U S A. April 27, 1999; 96 (9): 4797-802.

Cell cycle analysis and synchronization of the Xenopus laevis XL2 cell line: study of the kinesin related protein XlEg5., Uzbekov R, Prigent C, Arlot-Bonnemains Y., Microsc Res Tech. April 1, 1999; 45 (1): 31-42.

Speedy: a novel cell cycle regulator of the G2/M transition., Lenormand JL, Dellinger RW, Knudsen KE, Subramani S, Donoghue DJ., EMBO J. April 1, 1999; 18 (7): 1869-77.

Cyclin-dependent kinase control of centrosome duplication., Lacey KR, Jackson PK, Stearns T., Proc Natl Acad Sci U S A. March 16, 1999; 96 (6): 2817-22.

Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts., Hinchcliffe EH, Li C, Thompson EA, Maller JL, Sluder G., Science. February 5, 1999; 283 (5403): 851-4.

Structural interpretation of site-directed mutagenesis and specificity of the catalytic subunit of protein kinase CK2 using comparative modelling., Srinivasan N, Antonelli M, Jacob G, Korn I, Romero F, Jedlicki A, Dhanaraj V, Sayed MF, Blundell TL, Allende CC, Allende JE., Protein Eng. February 1, 1999; 12 (2): 119-27.

Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1., Moore JD, Yang J, Truant R, Kornbluth S., J Cell Biol. January 25, 1999; 144 (2): 213-24.              

Cyclin-dependent kinases at the G1-S transition of the mammalian cell cycle., Hengstschläger M, Braun K, Soucek T, Miloloza A, Hengstschläger-Ottnad E., Mutat Res. January 1, 1999; 436 (1): 1-9.

Functional interaction between the bovine papillomavirus virus type 1 replicative helicase E1 and cyclin E-Cdk2., Cueille N, Nougarede R, Mechali F, Philippe M, Bonne-Andrea C., J Virol. September 1, 1998; 72 (9): 7255-62.

Cdk2 activity is dispensable for the onset of DNA replication during the first mitotic cycles of the sea urchin early embryo., Moreau JL, Marques F, Barakat A, Schatt P, Lozano JC, Peaucellier G, Picard A, Genevière AM., Dev Biol. August 15, 1998; 200 (2): 182-97.

Dynamics of the cell cycle engine: Cdk2-kinase and the transition into mitosis., Kaern M, Hunding A., J Theor Biol. July 7, 1998; 193 (1): 47-57.

Transcription factor E2F and cyclin E-Cdk2 complex cooperate to induce chromosomal DNA replication in Xenopus oocytes., Akamatsu E, Tanaka T, Kato JY., J Biol Chem. June 26, 1998; 273 (26): 16494-500.

Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2., Hua XH, Newport J., J Cell Biol. January 26, 1998; 140 (2): 271-81.            

Induction of a G2-phase arrest in Xenopus egg extracts by activation of p42 mitogen-activated protein kinase., Walter SA, Guadagno TM, Ferrell JE., Mol Biol Cell. November 1, 1997; 8 (11): 2157-69.

Proteolysis and DNA replication: the CDC34 requirement in the Xenopus egg cell cycle., Yew PR, Kirschner MW., Science. September 12, 1997; 277 (5332): 1672-6.

Is Cdk7/cyclin H/MAT1 the genuine cdk activating kinase in cycling Xenopus egg extracts?, Fesquet D, Morin N, Doree M, Devault A., Oncogene. September 1, 1997; 15 (11): 1303-7.

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