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Summary Expression Phenotypes Gene Literature (550) GO Terms (6) Nucleotides (309) Proteins (58) Interactants (2147) Wiki
XB--485219

Papers associated with otx2



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A gene regulatory program controlling early Xenopus mesendoderm formation: Network conservation and motifs., Charney RM, Paraiso KD, Blitz IL, Cho KWY., Semin Cell Dev Biol. June 1, 2017; 66 12-24.    

Frizzled 3 acts upstream of Alcam during embryonic eye development., Seigfried FA, Cizelsky W, Pfister AS, Dietmann P, Walther P, Kühl M, Kühl SJ., Dev Biol. June 1, 2017; 426 (1): 69-83.                        

Brg1 chromatin remodeling ATPase balances germ layer patterning by amplifying the transcriptional burst at midblastula transition., Wagner G, Singhal N, Nicetto D, Straub T, Kremmer E, Rupp RAW., PLoS Genet. May 12, 2017; 13 (5): e1006757.                                    

Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis., Pitcairn E, Harris H, Epiney J, Pai VP, Lemire JM, Ye B, Shi NQ, Levin M, McLaughlin KA., Commun Integr Biol. May 10, 2017; 10 (3): e1309488.                            

sall1 and sall4 repress pou5f3 family expression to allow neural patterning, differentiation, and morphogenesis in Xenopus laevis., Exner CRT, Kim AY, Mardjuki SM, Harland RM., Dev Biol. May 1, 2017; 425 (1): 33-43.                                    

Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis., Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.                        

SMOC can act as both an antagonist and an expander of BMP signaling., Thomas JT, Eric Dollins D, Andrykovich KR, Chu T, Stultz BG, Hursh DA, Moos M., Elife. March 21, 2017; 6                         

Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways., Jullien J, Vodnala M, Pasque V, Oikawa M, Miyamoto K, Allen G, David SA, Brochard V, Wang S, Bradshaw C, Koseki H, Sartorelli V, Beaujean N, Gurdon J., Mol Cell. March 2, 2017; 65 (5): 873-884.e8.                        

The Nedd4 binding protein 3 is required for anterior neural development in Xenopus laevis., Kiem LM, Dietmann P, Linnemann A, Schmeisser MJ, Kühl SJ., Dev Biol. March 1, 2017; 423 (1): 66-76.                            

Tbx2 regulates anterior neural specification by repressing FGF signaling pathway., Cho GS, Park DS, Choi SC, Han JK., Dev Biol. January 15, 2017; 421 (2): 183-193.              

Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development., Neilson KM, Abbruzzesse G, Kenyon K, Bartolo V, Krohn P, Alfandari D, Alfandari D, Moody SA., Dev Biol. January 15, 2017; 421 (2): 171-182.                    

FoxD1 protein interacts with Wnt and BMP signaling to differentially pattern mesoderm and neural tissue., Polevoy H, Malyarova A, Fonar Y, Elias S, Frank D., Int J Dev Biol. January 1, 2017; 61 (3-4-5): 293-302.              

MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus., Vacca B, Sanchez-Heras E, Steed E, Balda MS, Ohnuma SI, Sasai N, Mayor R, Matter K., Biol Open. November 15, 2016; 5 (11): 1631-1641.                          

Cholesterol-rich membrane microdomains modulate Wnt/β-catenin morphogen gradient during Xenopus development., Reis AH, Moreno MM, Maia LA, Oliveira FP, Santos AS, Abreu JG., Mech Dev. November 1, 2016; 142 30-39.                        

Autoregulation of retinal homeobox (rax) gene promoter activity through a highly conserved genomic element., Kelly LE, Martinez-De Luna RI, El-Hodiri HM., Genesis. November 1, 2016; 54 (11): 562-567.      

An Evolutionarily Conserved Network Mediates Development of the zona limitans intrathalamica, a Sonic Hedgehog-Secreting Caudal Forebrain Signaling Center., Sena E, Feistel K, Durand BC., J Dev Biol. October 20, 2016; 4 (4):       

Tbx3 represses bmp4 expression and, with Pax6, is required and sufficient for retina formation., Motahari Z, Martinez-De Luna RI, Viczian AS, Zuber ME., Development. October 1, 2016; 143 (19): 3560-3572.                                      

The positive transcriptional elongation factor (P-TEFb) is required for neural crest specification., Hatch VL, Marin-Barba M, Moxon S, Ford CT, Ward NJ, Tomlinson ML, Desanlis I, Hendry AE, Hontelez S, van Kruijsbergen I, Veenstra GJ, Münsterberg AE, Wheeler GN., Dev Biol. August 15, 2016; 416 (2): 361-72.                                    

Bioelectric signalling via potassium channels: a mechanism for craniofacial dysmorphogenesis in KCNJ2-associated Andersen-Tawil Syndrome., Adams DS, Uzel SG, Akagi J, Wlodkowic D, Andreeva V, Yelick PC, Devitt-Lee A, Pare JF, Levin M., J Physiol. June 15, 2016; 594 (12): 3245-70.                              

Activation of a T-box-Otx2-Gsc gene network independent of TBP and TBP-related factors., Gazdag E, Jacobi UG, van Kruijsbergen I, Weeks DL, Veenstra GJ., Development. April 15, 2016; 143 (8): 1340-50.                    

Hmga2 is required for neural crest cell specification in Xenopus laevis., Macrì S, Simula L, Pellarin I, Pegoraro S, Onorati M, Sgarra R, Manfioletti G, Vignali R., Dev Biol. March 1, 2016; 411 (1): 25-37.                                        

Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis., Eroshkin FM, Nesterenko AM, Borodulin AV, Martynova NY, Ermakova GV, Gyoeva FK, Orlov EE, Belogurov AA, Lukyanov KA, Bayramov AV, Zaraisky AG., Sci Rep. January 22, 2016; 6 23049.                                                            

Specification of anteroposterior axis by combinatorial signaling during Xenopus development., Carron C, Shi DL., Wiley Interdiscip Rev Dev Biol. January 1, 2016; 5 (2): 150-68.            

Identification of microRNAs and microRNA targets in Xenopus gastrulae: The role of miR-26 in the regulation of Smad1., Liu C, Lou CH, Shah V, Ritter R, Talley J, Soibam B, Benham A, Zhu H, Perez E, Shieh YE, Gunaratne PH, Sater AK., Dev Biol. January 1, 2016; 409 (1): 26-38.                

G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus., Miyagi A, Negishi T, Yamamoto TS, Ueno N., Dev Biol. November 1, 2015; 407 (1): 131-44.                                          

Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus., Thélie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, Borromeo MD, Kricha S, Lahaye F, Croce J, Cerda-Moya G, Ordoño Fernandez J, Bolle B, Lewis KE, Sander M, Pierani A, Schubert M, Johnson JE, Kintner CR, Pieler T, Van Lint C, Henningfeld KA, Bellefroid EJ, Van Campenhout C., Development. October 1, 2015; 142 (19): 3416-28.                                    

The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway., Luehders K, Sasai N, Davaapil H, Kurosawa-Yoshida M, Hiura H, Brah T, Ohnuma S., Development. October 1, 2015; 142 (19): 3351-61.                              

JmjC Domain-containing Protein 6 (Jmjd6) Derepresses the Transcriptional Repressor Transcription Factor 7-like 1 (Tcf7l1) and Is Required for Body Axis Patterning during Xenopus Embryogenesis., Zhang X, Gao Y, Lu L, Zhang Z, Zhang Z, Gan S, Xu L, Lei A, Cao Y, Cao Y., J Biol Chem. August 14, 2015; 290 (33): 20273-83.                      

Xenopus Pkdcc1 and Pkdcc2 Are Two New Tyrosine Kinases Involved in the Regulation of JNK Dependent Wnt/PCP Signaling Pathway., Vitorino M, Silva AC, Inácio JM, Ramalho JS, Gur M, Fainsod A, Steinbeisser H, Belo JA., PLoS One. August 13, 2015; 10 (8): e0135504.                                    

Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin., Lu L, Gao Y, Zhang Z, Cao Q, Zhang X, Zou J, Cao Y., Dev Cell. June 22, 2015; 33 (6): 660-74.                                  

A time space translation hypothesis for vertebrate axial patterning., Durston AJ, Zhu K., Semin Cell Dev Biol. June 1, 2015; 42 86-93.  

Early neural ectodermal genes are activated by Siamois and Twin during blastula stages., Klein SL, Moody SA., Genesis. May 1, 2015; 53 (5): 308-20.          

cnrip1 is a regulator of eye and neural development in Xenopus laevis., Zheng X, Suzuki T, Takahashi C, Nishida E, Kusakabe M., Genes Cells. April 1, 2015; 20 (4): 324-39.                          

Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation., Zhang X, Cheong SM, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X., Dev Cell. March 23, 2015; 32 (6): 719-30.                                  

The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Acosta H, Iliev D, Grahn TH, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM., Development. March 15, 2015; 142 (6): 1146-58.                                    

Endogenous gradients of resting potential instructively pattern embryonic neural tissue via Notch signaling and regulation of proliferation., Pai VP, Lemire JM, Paré JF, Lin G, Chen Y, Levin M., J Neurosci. March 11, 2015; 35 (10): 4366-85.                    

Efficient retina formation requires suppression of both Activin and BMP signaling pathways in pluripotent cells., Wong KA, Trembley M, Abd Wahab S, Viczian AS., Biol Open. March 6, 2015; 4 (4): 573-83.                

E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation., Wills AE, Baker JC., Dev Cell. February 9, 2015; 32 (3): 345-57.                  

COUP-TFs and eye development., Tang K, Tsai SY, Tsai MJ., Biochim Biophys Acta. February 1, 2015; 1849 (2): 201-9.    

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism., Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M., Sci Rep. January 12, 2015; 5 11603.                                  

Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites., Kim YJ, Bahn M, Kim YH, Shin JY, Cheong SW, Ju BG, Kim WS, Yeo CY., Dev Biol. January 1, 2015; 397 (1): 129-39.                                          

Temporal and spatial expression analysis of peripheral myelin protein 22 (Pmp22) in developing Xenopus., Tae HJ, Rahman MM, Park BY., Gene Expr Patterns. January 1, 2015; 17 (1): 26-30.              

Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG, Predes D, Fonseca BF, Cerqueira DM, Reis AH, Dudenhoeffer AC, Borges HL, Mendes FA, Abreu JG., J Biol Chem. December 19, 2014; 289 (51): 35456-67.                  

PV.1 induced by FGF-Xbra functions as a repressor of neurogenesis in Xenopus embryos., Yoon J, Kim JH, Lee SY, Kim S, Park JB, Lee JY, Kim J., BMB Rep. December 1, 2014; 47 (12): 673-8.        

Genome-wide view of TGFβ/Foxh1 regulation of the early mesendoderm program., Chiu WT, Charney Le R, Blitz IL, Fish MB, Li Y, Biesinger J, Xie X, Cho KW., Development. December 1, 2014; 141 (23): 4537-47.                                  

Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development., Zhang S, Li J, Lea R, Vleminckx K, Vleminckx K, Amaya E., Development. December 1, 2014; 141 (24): 4794-805.                            

The conserved barH-like homeobox-2 gene barhl2 acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal forebrain signaling center induced by Sonic Hedgehog., Juraver-Geslin HA, Gómez-Skarmeta JL, Durand BC., Dev Biol. December 1, 2014; 396 (1): 107-20.                    

Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character., Fish MB, Nakayama T, Fisher M, Hirsch N, Cox A, Reeder R, Carruthers S, Hall A, Stemple DL, Grainger RM., Dev Biol. November 15, 2014; 395 (2): 317-330.                  

Developmental enhancers are marked independently of zygotic Nodal signals in Xenopus., Gupta R, Wills A, Ucar D, Baker J., Dev Biol. November 1, 2014; 395 (1): 38-49.            

Custos controls β-catenin to regulate head development during vertebrate embryogenesis., Komiya Y, Mandrekar N, Sato A, Dawid IB, Habas R., Proc Natl Acad Sci U S A. September 9, 2014; 111 (36): 13099-104.                                

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