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Summary Expression Phenotypes Gene Literature (182) GO Terms (1) Nucleotides (210) Proteins (55) Interactants (1420) Wiki
XB--478517

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The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C., Elife. January 14, 2020; 9                                                                                               

Modeling Bainbridge-Ropers Syndrome in Xenopus laevis Embryos., Lichtig H, Artamonov A, Polevoy H, Reid CD, Bielas SL, Frank D., Front Physiol. January 1, 2020; 11 75.                    

A unique role of thyroid hormone receptor β in regulating notochord resorption during Xenopus metamorphosis., Nakajima K, Tazawa I, Shi YB., Gen Comp Endocrinol. June 1, 2019; 277 66-72.            

AKT signaling displays multifaceted functions in neural crest development., Sittewelle M, Monsoro-Burq AH., Dev Biol. December 1, 2018; 444 Suppl 1 S144-S155.

Shared evolutionary origin of vertebrate neural crest and cranial placodes., Horie R, Hazbun A, Chen K, Cao C, Levine M, Horie T., Nature. August 1, 2018; 560 (7717): 228-232.      

Transcriptomics of dorso-ventral axis determination in Xenopus tropicalis., Monteiro RS, Gentsch GE, Smith JC., Dev Biol. July 15, 2018; 439 (2): 69-79.                                    

Head formation requires Dishevelled degradation that is mediated by March2 in concert with Dapper1., Lee H, Lee H, Cheong SM, Han W, Koo Y, Jo SB, Cho GS, Yang JS, Kim S, Han JK., Development. April 10, 2018; 145 (7):               

Intracellular calcium signal at the leading edge regulates mesodermal sheet migration during Xenopus gastrulation., Hayashi K, Yamamoto TS, Ueno N., Sci Rep. February 5, 2018; 8 (1): 2433.              

RAPGEF5 Regulates Nuclear Translocation of β-Catenin., Griffin JN, Del Viso F, Duncan AR, Robson A, Hwang W, Kulkarni S, Liu KJ, Liu KJ, Khokha MK., Dev Cell. January 22, 2018; 44 (2): 248-260.e4.                                                

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.                                

hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus., Prager A, Hagenlocher C, Ott T, Schambony A, Feistel K., Dev Biol. October 1, 2017; 430 (1): 188-201.                      

interleukin-11 induces and maintains progenitors of different cell lineages during Xenopus tadpole tail regeneration., Tsujioka H, Kunieda T, Katou Y, Shirahige K, Fukazawa T, Kubo T., Nat Commun. September 8, 2017; 8 (1): 495.                                

Nodal/Activin Pathway is a Conserved Neural Induction Signal in Chordates., Le Petillon Y, Luxardi G, Scerbo P, Cibois M, Leon A, Subirana L, Irimia M, Kodjabachian L, Escriva H, Bertrand S., Nat Ecol Evol. August 1, 2017; 1 (8): 1192-1200.                                

A catalog of Xenopus tropicalis transcription factors and their regional expression in the early gastrula stage embryo., Blitz IL, Paraiso KD, Patrushev I, Chiu WTY, Cho KWY, Gilchrist MJ., Dev Biol. June 15, 2017; 426 (2): 409-417.        

RARβ2 is required for vertebrate somitogenesis., Janesick A, Tang W, Nguyen TTL, Blumberg B., Development. June 1, 2017; 144 (11): 1997-2008.                                              

sall1 and sall4 repress pou5f3 family expression to allow neural patterning, differentiation, and morphogenesis in Xenopus laevis., Exner CRT, Kim AY, Mardjuki SM, Harland RM., Dev Biol. May 1, 2017; 425 (1): 33-43.                                    

FoxD1 protein interacts with Wnt and BMP signaling to differentially pattern mesoderm and neural tissue., Polevoy H, Malyarova A, Fonar Y, Elias S, Frank D., Int J Dev Biol. January 1, 2017; 61 (3-4-5): 293-302.              

Activation of a T-box-Otx2-Gsc gene network independent of TBP and TBP-related factors., Gazdag E, Jacobi UG, van Kruijsbergen I, Weeks DL, Veenstra GJ., Development. April 15, 2016; 143 (8): 1340-50.                    

PLD1 regulates Xenopus convergent extension movements by mediating Frizzled7 endocytosis for Wnt/PCP signal activation., Lee H, Lee SJ, Kim GH, Yeo I, Han JK., Dev Biol. March 1, 2016; 411 (1): 38-49.                          

Specification of anteroposterior axis by combinatorial signaling during Xenopus development., Carron C, Shi DL., Wiley Interdiscip Rev Dev Biol. January 1, 2016; 5 (2): 150-68.            

Identification of microRNAs and microRNA targets in Xenopus gastrulae: The role of miR-26 in the regulation of Smad1., Liu C, Lou CH, Shah V, Ritter R, Talley J, Soibam B, Benham A, Zhu H, Perez E, Shieh YE, Gunaratne PH, Sater AK., Dev Biol. January 1, 2016; 409 (1): 26-38.                

Xenopus CAF1 requires NOT1-mediated interaction with 4E-T to repress translation in vivo., Waghray S, Williams C, Coon JJ, Wickens M., RNA. July 1, 2015; 21 (7): 1335-45.

Early neural ectodermal genes are activated by Siamois and Twin during blastula stages., Klein SL, Moody SA., Genesis. May 1, 2015; 53 (5): 308-20.          

Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation., Zhang X, Cheong SM, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X., Dev Cell. March 23, 2015; 32 (6): 719-30.                                  

The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus., Griffin JN, Sondalle SB, Del Viso F, Baserga SJ, Khokha MK., PLoS Genet. March 10, 2015; 11 (3): e1005018.                              

Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression., Nelson AC, Cutty SJ, Niini M, Stemple DL, Flicek P, Houart C, Bruce AE, Wardle FC., BMC Biol. October 3, 2014; 12 81.            

Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification., Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M., Nat Commun. July 9, 2014; 5 4322.        

Active repression by RARγ signaling is required for vertebrate axial elongation., Janesick A, Nguyen TT, Aisaki K, Igarashi K, Kitajima S, Chandraratna RA, Kanno J, Blumberg B., Development. June 1, 2014; 141 (11): 2260-70.                    

High-resolution analysis of gene activity during the Xenopus mid-blastula transition., Collart C, Owens ND, Bhaw-Rosun L, Cooper B, De Domenico E, Patrushev I, Sesay AK, Smith JN, Smith JC, Gilchrist MJ., Development. May 1, 2014; 141 (9): 1927-39.                  

Zygotic expression of Exostosin1 (Ext1) is required for BMP signaling and establishment of dorsal-ventral pattern in Xenopus., Shieh YE, Wells DE, Sater AK., Int J Dev Biol. January 1, 2014; 58 (1): 27-34.          

Left-right patterning in Xenopus conjoined twin embryos requires serotonin signaling and gap junctions., Vandenberg LN, Blackiston DJ, Rea AC, Dore TM, Levin M., Int J Dev Biol. January 1, 2014; 58 (10-12): 799-809.                

A conserved Oct4/POUV-dependent network links adhesion and migration to progenitor maintenance., Livigni A, Peradziryi H, Sharov AA, Chia G, Hammachi F, Migueles RP, Sukparangsi W, Pernagallo S, Bradley M, Nichols J, Ko MSH, Brickman JM., Curr Biol. November 18, 2013; 23 (22): 2233-2244.                                    

Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterning., Kam RK, Shi W, Chan SO, Chen Y, Xu G, Lau CB, Fung KP, Chan WY, Zhao H., J Biol Chem. November 1, 2013; 288 (44): 31477-87.                    

Directional migration of leading-edge mesoderm generates physical forces: Implication in Xenopus notochord formation during gastrulation., Hara Y, Nagayama K, Yamamoto TS, Matsumoto T, Suzuki M, Ueno N., Dev Biol. October 15, 2013; 382 (2): 482-95.                  

The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F, Hu W, Xian J, Ohnuma S, Brenton JD., Dev Biol. July 1, 2013; 379 (1): 16-27.                            

β-Arrestin 1 mediates non-canonical Wnt pathway to regulate convergent extension movements., Kim GH, Park EC, Lee H, Lee H, Na HJ, Choi SC, Han JK., Biochem Biophys Res Commun. May 31, 2013; 435 (2): 182-7.                  

An intact brachyury function is necessary to prevent spurious axial development in Xenopus laevis., Aguirre CE, Murgan S, Carrasco AE, López SL., PLoS One. January 1, 2013; 8 (1): e54777.                                      

Essential role of AWP1 in neural crest specification in Xenopus., Seo JH, Park DS, Hong M, Chang EJ, Choi SC., Int J Dev Biol. January 1, 2013; 57 (11-12): 829-36.                  

Gastrulation and pre-gastrulation morphogenesis, inductions, and gene expression: similarities and dissimilarities between urodelean and anuran embryos., Kaneda T, Motoki JY., Dev Biol. September 1, 2012; 369 (1): 1-18.          

Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation., Zhang X, Abreu JG, Yokota C, MacDonald BT, Singh S, Coburn KL, Cheong SM, Zhang MM, Ye QZ, Hang HC, Steen H, He X., Cell. June 22, 2012; 149 (7): 1565-77.                      

TAK1 promotes BMP4/Smad1 signaling via inhibition of erk MAPK: a new link in the FGF/BMP regulatory network., Liu C, Goswami M, Talley J, Chesser-Martinez PL, Lou CH, Sater AK., Differentiation. April 1, 2012; 83 (4): 210-9.                  

Xenopus Zic3 controls notochord and organizer development through suppression of the Wnt/β-catenin signaling pathway., Fujimi TJ, Hatayama M, Aruga J., Dev Biol. January 15, 2012; 361 (2): 220-31.                          

A revised model of Xenopus dorsal midline development: differential and separable requirements for Notch and Shh signaling., Peyrot SM, Wallingford JB, Harland RM., Dev Biol. April 15, 2011; 352 (2): 254-66.                              

SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos., Wu MY, Ramel MC, Howell M, Hill CS., PLoS Biol. February 15, 2011; 9 (2): e1000593.                              

Yes-associated protein 65 (YAP) expands neural progenitors and regulates Pax3 expression in the neural plate border zone., Gee ST, Milgram SL, Kramer KL, Conlon FL, Moody SA., PLoS One. January 1, 2011; 6 (6): e20309.                  

Long-distance signals are required for morphogenesis of the regenerating Xenopus tadpole tail, as shown by femtosecond-laser ablation., Mondia JP, Levin M, Omenetto FG, Orendorff RD, Branch MR, Adams DS., PLoS One. January 1, 2011; 6 (9): e24953.            

Xenopus furry contributes to release of microRNA gene silencing., Goto T, Fukui A, Shibuya H, Keller R, Asashima M., Proc Natl Acad Sci U S A. November 9, 2010; 107 (45): 19344-9.                        

Anterior neural development requires Del1, a matrix-associated protein that attenuates canonical Wnt signaling via the Ror2 pathway., Takai A, Inomata H, Arakawa A, Yakura R, Matsuo-Takasaki M, Sasai Y., Development. October 1, 2010; 137 (19): 3293-302.            

Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor., Buechling T, Bartscherer K, Ohkawara B, Chaudhary V, Spirohn K, Niehrs C, Boutros M., Curr Biol. July 27, 2010; 20 (14): 1263-8.  

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