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Summary Expression Phenotypes Gene Literature (550) GO Terms (6) Nucleotides (309) Proteins (58) Interactants (2147) Wiki
XB--485219

Papers associated with otx2



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Patterning of the Vertebrate Head in Time and Space by BMP Signaling., Zhu K, Spaink HP, Durston AJ., J Dev Biol. July 3, 2023; 11 (3):         

The complete dorsal structure is formed from only the blastocoel roof of Xenopus blastula: insight into the gastrulation movement evolutionarily conserved among chordates., Sato Y, Narasaki I, Kunimoto T, Moriyama Y, Hashimoto C., Dev Genes Evol. June 1, 2023; 233 (1): 1-12.                

Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development., Cowell LM, King M, West H, Broadsmith M, Genever P, Pownall ME, Isaacs HV., PLoS One. January 1, 2023; 18 (10): e0286040.                                  

Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions., Johnson K, Freedman S, Braun R, LaBonne C., BMC Genomics. October 23, 2022; 23 (1): 723.                                  

Tissue Rotation of the Xenopus Anterior-Posterior Neural Axis Reveals Profound but Transient Plasticity at the Mid-Gastrula Stage., Bolkhovitinov L, Weselman BT, Shaw GA, Dong C, Giribhattanavar J, Saha MS., J Dev Biol. September 10, 2022; 10 (3):                           

Functions of block of proliferation 1 during anterior development in Xenopus laevis., Gärtner C, Meßmer A, Dietmann P, Kühl M, Kühl SJ., PLoS One. August 2, 2022; 17 (8): e0273507.                        

Xenopus Dusp6 modulates FGF signaling to precisely pattern pre-placodal ectoderm., Tsukano K, Yamamoto T, Watanabe T, Michiue T., Dev Biol. August 1, 2022; 488 81-90.                          

FGF/MAPK/Ets signaling in Xenopus ectoderm contributes to neural induction and patterning in an autonomous and paracrine manner, respectively., Hongo I, Okamoto H., Cells Dev. June 1, 2022; 170 203769.

Hif1α and Wnt are required for posterior gene expression during Xenopus tropicalis tail regeneration., Patel JH, Schattinger PA, Takayoshi EE, Wills AE., Dev Biol. March 1, 2022; 483 157-168.                  

Uncovering the mesendoderm gene regulatory network through multi-omic data integration., Jansen C, Paraiso KD, Zhou JJ, Blitz IL, Fish MB, Charney RM, Cho JS, Yasuoka Y, Sudou N, Bright AR, Wlizla M, Veenstra GJC, Taira M, Zorn AM, Mortazavi A, Cho KWY., Cell Rep. February 15, 2022; 38 (7): 110364.                            

Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development., Sun J, Yoon J, Lee M, Lee HK, Hwang YS, Daar IO., Cell Rep. February 1, 2022; 38 (5): 110312.                                          

Proteomic screen reveals diverse protein transport between connected neurons in the visual system., Schiapparelli LM, Sharma P, He HY, Li J, Shah SH, McClatchy DB, Ma Y, Liu HH, Goldberg JL, Yates JR, Cline HT., Cell Rep. January 25, 2022; 38 (4): 110287.                                  

Temporal and spatial transcriptomic dynamics across brain development in Xenopus laevis tadpoles., Ta AC, Huang LC, McKeown CR, Bestman JE, Van Keuren-Jensen K, Cline HT., G3 (Bethesda). January 4, 2022; 12 (1):               

Reduced Retinoic Acid Signaling During Gastrulation Induces Developmental Microcephaly., Gur M, Bendelac-Kapon L, Shabtai Y, Pillemer G, Fainsod A., Front Cell Dev Biol. January 1, 2022; 10 844619.                        

The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways., Schreiner C, Kernl B, Dietmann P, Riegger RJ, Kühl M, Kühl SJ., Front Cell Dev Biol. January 1, 2022; 10 777121.                        

Goosecoid Controls Neuroectoderm Specification via Dual Circuits of Direct Repression and Indirect Stimulation in Xenopus Embryos., Umair Z, Kumar V, Goutam RS, Kumar S, Kumar S, Lee U, Kim J., Mol Cells. October 31, 2021; 44 (10): 723-735.          

A systemic cell cycle block impacts stage-specific histone modification profiles during Xenopus embryogenesis., Pokrovsky D, Forné I, Straub T, Imhof A, Rupp RAW., PLoS Biol. September 1, 2021; 19 (9): e3001377.                        

Modeling human congenital disorders with neural crest developmental defects using patient-derived induced pluripotent stem cells., Okuno H, Okano H., Regen Ther. August 24, 2021; 18 275-280.      

Molecular mechanisms of hearing loss in Nager syndrome., Maharana SK, Saint-Jeannet JP., Dev Biol. August 1, 2021; 476 200-208.            

Temporal transcriptomic profiling reveals dynamic changes in gene expression of Xenopus animal cap upon activin treatment., Satou-Kobayashi Y, Kim JD, Fukamizu A, Asashima M., Sci Rep. July 15, 2021; 11 (1): 14537.          

Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification., Reis AH, Sokol SY., Sci Rep. June 28, 2021; 11 (1): 13433.            

The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus., Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y., Proc Natl Acad Sci U S A. May 18, 2021; 118 (20):           

Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., Bright AR, van Genesen S, Li Q, Grasso A, Frölich S, van der Sande M, van Heeringen SJ, Veenstra GJC., EMBO J. May 3, 2021; 40 (9): e104913.                        

A temporally resolved transcriptome for developing "Keller" explants of the Xenopus laevis dorsal marginal zone., Kakebeen AD, Huebner RJ, Shindo A, Kwon K, Kwon T, Wills AE, Wallingford JB., Dev Dyn. May 1, 2021; 250 (5): 717-731.              

Furry is required for cell movements during gastrulation and functionally interacts with NDR1., Cervino AS, Moretti B, Stuckenholz C, Grecco HE, Davidson LA, Davidson LA, Cirio MC., Sci Rep. March 23, 2021; 11 (1): 6607.                                  

Rab11fip5 regulates telencephalon development via ephrinB1 recycling., Yoon J, Garo J, Lee M, Sun J, Hwang YS, Daar IO., Development. February 2, 2021; 148 (3):                                                             

Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT, Willsey HR., Genesis. February 1, 2021; 59 (1-2): e23405.          

Establishing embryonic territories in the context of Wnt signaling., Velloso I, Maia LA, Amado NG, Reis AH, He X, Abreu JG., Int J Dev Biol. January 1, 2021; 65 (4-5-6): 227-233.      

The Secreted Protein Disulfide Isomerase Ag1 Lost by Ancestors of Poorly Regenerating Vertebrates Is Required for Xenopus laevis Tail Regeneration., Ivanova AS, Tereshina MB, Araslanova KR, Martynova NY, Zaraisky AG., Front Cell Dev Biol. January 1, 2021; 9 738940.                  

The tetraspanin Cd63 is required for eye morphogenesis in Xenopus., Kreis J, Bonß R, Vick P., MicroPubl Biol. November 27, 2020; 2020   

Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos., Umair Z, Kumar S, Rafiq K, Kumar V, Reman ZU, Lee SH, Kim S, Lee JY, Lee U, Kim J., Anim Cells Syst (Seoul). November 27, 2020; 24 (6): 359-370.            

Foxd4l1.1 negatively regulates transcription of neural repressor ventx1.1 during neuroectoderm formation in Xenopus embryos., Kumar S, Kumar S, Umair Z, Kumar V, Kumar S, Lee U, Kim J., Sci Rep. October 8, 2020; 10 (1): 16780.            

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           

Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network., Mukherjee S, Chaturvedi P, Rankin SA, Rankin SA, Fish MB, Wlizla M, Paraiso KD, MacDonald M, Chen X, Weirauch MT, Blitz IL, Cho KW, Zorn AM., Elife. September 7, 2020; 9                           

Interplay of TRIM2 E3 Ubiquitin Ligase and ALIX/ESCRT Complex: Control of Developmental Plasticity During Early Neurogenesis., Lokapally A, Neuhaus H, Herfurth J, Hollemann T., Cells. July 20, 2020; 9 (7):                                           

Dach1 regulates neural crest migration during embryonic development., Kim YK, Lee H, Ismail T, Kim Y, Lee HS., Biochem Biophys Res Commun. July 5, 2020; 527 (4): 896-901.        

Heparan sulfate proteoglycans regulate BMP signalling during neural crest induction., Pegge J, Tatsinkam AJ, Rider CC, Bell E., Dev Biol. April 15, 2020; 460 (2): 108-114.        

Six1 proteins with human branchio-oto-renal mutations differentially affect cranial gene expression and otic development., Shah AM, Krohn P, Baxi AB, Tavares ALP, Sullivan CH, Chillakuru YR, Majumdar HD, Neilson KM, Moody SA., Dis Model Mech. March 3, 2020; 13 (3):                                               

miR-199 plays both positive and negative regulatory roles in Xenopus eye development., Ritter RA, Ulrich CH, Brzezinska BN, Shah VV, Zamora MJ, Kelly LE, El-Hodiri HM, Sater AK., Genesis. March 1, 2020; 58 (3-4): e23354.                        

The regulatory proteins DSCR6 and Ezh2 oppositely regulate Stat3 transcriptional activity in mesoderm patterning during Xenopus development., Loreti M, Shi DL, Carron C., J Biol Chem. February 28, 2020; 295 (9): 2724-2735.                

The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C., Elife. January 14, 2020; 9                                                                                               

Modeling Bainbridge-Ropers Syndrome in Xenopus laevis Embryos., Lichtig H, Artamonov A, Polevoy H, Reid CD, Bielas SL, Frank D., Front Physiol. January 1, 2020; 11 75.                    

HCN2 Channel-Induced Rescue of Brain Teratogenesis via Local and Long-Range Bioelectric Repair., Pai VP, Cervera J, Mafe S, Willocq V, Lederer EK, Levin M., Front Cell Neurosci. January 1, 2020; 14 136.                      

MiR-9 and the Midbrain-Hindbrain Boundary: A Showcase for the Limited Functional Conservation and Regulatory Complexity of MicroRNAs., Alwin Prem Anand A, Alvarez-Bolado G, Wizenmann A., Front Cell Dev Biol. January 1, 2020; 8 586158.  

Preventing Ethanol-Induced Brain and Eye Morphology Defects Using Optogenetics., Pai VP, Adams DS., Bioelectricity. December 1, 2019; 1 (4): 260-272.

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Kuznetsov JN, Aguero TH, Owens DA, Kurtenbach S, Field MG, Durante MA, Rodriguez DA, King ML, Harbour JW., Sci Adv. September 18, 2019; 5 (9): eaax1738.        

Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome., Greenberg RS, Long HK, Swigut T, Wysocka J., Cell. September 5, 2019; 178 (6): 1421-1436.e24.                                

Microsyntenic Clusters Reveal Conservation of lncRNAs in Chordates Despite Absence of Sequence Conservation., Herrera-Úbeda C, Marín-Barba M, Navas-Pérez E, Gravemeyer J, Albuixech-Crespo B, Wheeler GN, Garcia-Fernàndez J., Biology (Basel). August 24, 2019; 8 (3):             

Evolution of cis-regulatory modules for the head organizer gene goosecoid in chordates: comparisons between Branchiostoma and Xenopus., Yasuoka Y, Tando Y, Kubokawa K, Taira M., Zoological Lett. August 2, 2019; 5 27.                

Cdc2-like kinase 2 (Clk2) promotes early neural development in Xenopus embryos., Virgirinia RP, Jahan N, Okada M, Takebayashi-Suzuki K, Yoshida H, Nakamura M, Akao H, Yoshimoto Y, Fatchiyah F, Ueno N, Suzuki A., Dev Growth Differ. August 1, 2019; 61 (6): 365-377.                              

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