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Summary Expression Phenotypes Gene Literature (197) GO Terms (5) Nucleotides (130) Proteins (44) Interactants (1264) Wiki
XB--481643

Papers associated with dkk1



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MesP1 drives vertebrate cardiovascular differentiation through Dkk-1-mediated blockade of Wnt-signalling., David R, Brenner C, Stieber J, Schwarz F, Brunner S, Vollmer M, Mentele E, Müller-Höcker J, Kitajima S, Lickert H, Rupp R, Franz WM., Nat Cell Biol. March 1, 2008; 10 (3): 338-45.


Context-dependent activation or inhibition of Wnt-beta-catenin signaling by Kremen., Cselenyi CS, Lee E, Lee E., Sci Signal. February 26, 2008; 1 (8): pe10.


Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction., Pinho S, Niehrs C., Differentiation. December 1, 2007; 75 (10): 957-67.            


Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling., Hassler C, Cruciat CM, Huang YL, Kuriyama S, Mayor R, Niehrs C., Development. December 1, 2007; 134 (23): 4255-63.      


Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal., Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM, De Robertis EM., Cell. November 30, 2007; 131 (5): 980-93.      


Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells., Sinner D, Kordich JJ, Spence JR, Opoka R, Rankin S, Rankin S, Lin SC, Jonatan D, Zorn AM, Wells JM., Mol Cell Biol. November 1, 2007; 27 (22): 7802-15.                


Neural crests are actively precluded from the anterior neural fold by a novel inhibitory mechanism dependent on Dickkopf1 secreted by the prechordal mesoderm., Carmona-Fontaine C, Acuña G, Ellwanger K, Niehrs C, Mayor R., Dev Biol. September 15, 2007; 309 (2): 208-21.              


Wnt/beta-catenin signaling has an essential role in the initiation of limb regeneration., Yokoyama H, Ogino H, Stoick-Cooper CL, Grainger RM, Moon RT., Dev Biol. June 1, 2007; 306 (1): 170-8.        


Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development., McLin VA, Rankin SA, Zorn AM., Development. June 1, 2007; 134 (12): 2207-17.            


R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling., Wei Q, Yokota C, Semenov MV, Doble B, Woodgett J, He X., J Biol Chem. May 25, 2007; 282 (21): 15903-11.  


Evolution of axis specification mechanisms in jawed vertebrates: insights from a chondrichthyan., Coolen M, Sauka-Spengler T, Nicolle D, Le-Mentec C, Lallemand Y, Da Silva C, Plouhinec JL, Robert B, Wincker P, Shi DL, Mazan S., PLoS One. April 18, 2007; 2 (4): e374.              


Wnt/beta-catenin signaling controls Mespo expression to regulate segmentation during Xenopus somitogenesis., Wang J, Li S, Chen Y, Chen Y, Ding X., Dev Biol. April 15, 2007; 304 (2): 836-47.                    


Multiple functions of Cerberus cooperate to induce heart downstream of Nodal., Foley AC, Korol O, Timmer AM, Mercola M., Dev Biol. March 1, 2007; 303 (1): 57-65.        


Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek., Caneparo L, Huang YL, Staudt N, Tada M, Ahrendt R, Kazanskaya O, Niehrs C, Houart C., Genes Dev. February 15, 2007; 21 (4): 465-80.


Wnt/beta-catenin signaling regulates vertebrate limb regeneration., Kawakami Y, Rodriguez Esteban C, Raya M, Kawakami H, Martí M, Dubova I, Izpisúa Belmonte JC., Genes Dev. December 1, 2006; 20 (23): 3232-7.    


Suppressing Wnt signaling by the hedgehog pathway through sFRP-1., He J, Sheng T, Stelter AA, Li C, Zhang X, Sinha M, Luxon BA, Xie J., J Biol Chem. November 24, 2006; 281 (47): 35598-602.


Characterization of myeloid cells derived from the anterior ventral mesoderm in the Xenopus laevis embryo., Tashiro S, Sedohara A, Asashima M, Izutsu Y, Maéno M., Dev Growth Differ. October 1, 2006; 48 (8): 499-512.                    


Embryonic heart induction., Foley AC, Gupta RW, Guzzo RM, Korol O, Mercola M., Ann N Y Acad Sci. October 1, 2006; 1080 85-96.


FGF is essential for both condensation and mesenchymal-epithelial transition stages of pronephric kidney tubule development., Urban AE, Zhou X, Zhou X, Ungos JM, Raible DW, Altmann CR, Vize PD., Dev Biol. September 1, 2006; 297 (1): 103-17.                    


Expression of Dickkopf genes is strongly reduced in malignant melanoma., Kuphal S, Lodermeyer S, Bataille F, Schuierer M, Hoang BH, Bosserhoff AK., Oncogene. August 17, 2006; 25 (36): 5027-36.


NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)., Yamada M, Ohnishi J, Ohkawara B, Iemura S, Satoh K, Hyodo-Miura J, Kawachi K, Natsume T, Shibuya H., J Biol Chem. July 28, 2006; 281 (30): 20749-20760.                    


Genomic analysis of Xenopus organizer function., Hufton AL, Vinayagam A, Suhai S, Baker JC., BMC Dev Biol. June 6, 2006; 6 27.                  


The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition., Cruciat CM, Hassler C, Niehrs C., J Biol Chem. May 5, 2006; 281 (18): 12986-93.                        


Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines., Pukrop T, Klemm F, Hagemann T, Gradl D, Schulz M, Siemes S, Trümper L, Binder C., Proc Natl Acad Sci U S A. April 4, 2006; 103 (14): 5454-9.


An ancient Wnt-Dickkopf antagonism in Hydra., Guder C, Pinho S, Nacak TG, Schmidt HA, Hobmayer B, Niehrs C, Holstein TW., Development. March 1, 2006; 133 (5): 901-11.


Role of crescent in convergent extension movements by modulating Wnt signaling in early Xenopus embryogenesis., Shibata M, Itoh M, Hikasa H, Taira S, Taira M., Mech Dev. December 1, 2005; 122 (12): 1322-39.                    


Xnr2 and Xnr5 unprocessed proteins inhibit Wnt signaling upstream of dishevelled., Onuma Y, Takahashi S, Haramoto Y, Tanegashima K, Yokota C, Whitman M, Asashima M., Dev Dyn. December 1, 2005; 234 (4): 900-10.          


Antagonistic interaction between IGF and Wnt/JNK signaling in convergent extension in Xenopus embryo., Carron C, Bourdelas A, Li HY, Boucaut JC, Shi DL., Mech Dev. November 1, 2005; 122 (11): 1234-47.                


Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling., Swain RK, Katoh M, Medina A, Steinbeisser H., Cell Commun Signal. October 19, 2005; 3 12.          


An essential role of Xenopus Foxi1a for ventral specification of the cephalic ectoderm during gastrulation., Matsuo-Takasaki M, Matsumura M, Sasai Y., Development. September 1, 2005; 132 (17): 3885-94.                      


Xenopus hairy2b specifies anterior prechordal mesoderm identity within Spemann's organizer., Yamaguti M, Cho KW, Hashimoto C., Dev Dyn. September 1, 2005; 234 (1): 102-13.          


The doublesex-related gene, XDmrt4, is required for neurogenesis in the olfactory system., Huang X, Hong CS, O'Donnell M, Saint-Jeannet JP., Proc Natl Acad Sci U S A. August 9, 2005; 102 (32): 11349-54.                        


Comparative genomics on Dkk1 orthologs., Katoh Y, Katoh M., Int J Oncol. July 1, 2005; 27 (1): 275-9.


Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex., Foley AC, Mercola M., Genes Dev. February 1, 2005; 19 (3): 387-96.            


Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF., Yamamoto A, Nagano T, Takehara S, Hibi M, Aizawa S., Cell. January 28, 2005; 120 (2): 223-35.                      


FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development., Chamorro MN, Schwartz DR, Vonica A, Brivanlou AH, Cho KR, Varmus HE., EMBO J. January 12, 2005; 24 (1): 73-84.


Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition., Delaune E, Lemaire P, Kodjabachian L., Development. January 1, 2005; 132 (2): 299-310.                    


New roles for FoxH1 in patterning the early embryo., Kofron M, Puck H, Standley H, Wylie C, Old R, Whitman M, Heasman J., Development. October 1, 2004; 131 (20): 5065-78.              


A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways., Zuzarte-Luís V, Montero JA, Rodriguez-León J, Merino R, Rodríguez-Rey JC, Hurlé JM., Dev Biol. August 1, 2004; 272 (1): 39-52.


Expression analysis of chick Wnt and frizzled genes and selected inhibitors in early chick patterning., Chapman SC, Brown R, Lees L, Schoenwolf GC, Lumsden A., Dev Dyn. March 1, 2004; 229 (3): 668-76.


PP2A:B56epsilon is required for Wnt/beta-catenin signaling during embryonic development., Yang J, Wu J, Tan C, Klein PS., Development. December 1, 2003; 130 (23): 5569-78.            


Dkk1 and noggin cooperate in mammalian head induction., del Barco Barrantes I, Davidson G, Gröne HJ, Westphal H, Niehrs C., Genes Dev. September 15, 2003; 17 (18): 2239-44.


Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions., Hiratani I, Yamamoto N, Mochizuki T, Ohmori SY, Taira M., Development. September 1, 2003; 130 (17): 4161-75.                    


Induction of cardiomyocytes by GATA4 in Xenopus ectodermal explants., Latinkić BV, Kotecha S, Mohun TJ., Development. August 1, 2003; 130 (16): 3865-76.              


Ogon/Secreted Frizzled functions as a negative feedback regulator of Bmp signaling., Yabe T, Shimizu T, Muraoka O, Bae YK, Hirata T, Nojima H, Kawakami A, Hirano T, Hibi M., Development. June 1, 2003; 130 (12): 2705-16.


Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling., Mao B, Niehrs C., Gene. January 2, 2003; 302 (1-2): 179-83.        


Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning., Davidson G, Mao B, del Barco Barrantes I, Niehrs C., Development. December 1, 2002; 129 (24): 5587-96.        


Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins., Brott BK, Sokol SY., Mol Cell Biol. September 1, 2002; 22 (17): 6100-10.


The promise and perils of Wnt signaling through beta-catenin., Moon RT, Bowerman B, Boutros M, Perrimon N., Science. May 31, 2002; 296 (5573): 1644-6.


Bmp, Fgf and Wnt signalling in programmed cell death and chondrogenesis during vertebrate limb development: the role of Dickkopf-1., Grotewold L, Rüther U., Int J Dev Biol. January 1, 2002; 46 (7): 943-7.

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