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Summary Expression Phenotypes Gene Literature (550) GO Terms (6) Nucleotides (309) Proteins (58) Interactants (2147) Wiki
XB--485219

Papers associated with otx2



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Hmga2 is required for neural crest cell specification in Xenopus laevis., Macrì S, Simula L, Pellarin I, Pegoraro S, Onorati M, Sgarra R, Manfioletti G, Vignali R., Dev Biol. March 1, 2016; 411 (1): 25-37.                                        

Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis., Eroshkin FM, Nesterenko AM, Borodulin AV, Martynova NY, Ermakova GV, Gyoeva FK, Orlov EE, Belogurov AA, Lukyanov KA, Bayramov AV, Zaraisky AG., Sci Rep. January 22, 2016; 6 23049.                                                            

Specification of anteroposterior axis by combinatorial signaling during Xenopus development., Carron C, Shi DL., Wiley Interdiscip Rev Dev Biol. January 1, 2016; 5 (2): 150-68.            

Identification of microRNAs and microRNA targets in Xenopus gastrulae: The role of miR-26 in the regulation of Smad1., Liu C, Lou CH, Shah V, Ritter R, Talley J, Soibam B, Benham A, Zhu H, Perez E, Shieh YE, Gunaratne PH, Sater AK., Dev Biol. January 1, 2016; 409 (1): 26-38.                

G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus., Miyagi A, Negishi T, Yamamoto TS, Ueno N., Dev Biol. November 1, 2015; 407 (1): 131-44.                                          

Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus., Thélie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, Borromeo MD, Kricha S, Lahaye F, Croce J, Cerda-Moya G, Ordoño Fernandez J, Bolle B, Lewis KE, Sander M, Pierani A, Schubert M, Johnson JE, Kintner CR, Pieler T, Van Lint C, Henningfeld KA, Bellefroid EJ, Van Campenhout C., Development. October 1, 2015; 142 (19): 3416-28.                                    

The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway., Luehders K, Sasai N, Davaapil H, Kurosawa-Yoshida M, Hiura H, Brah T, Ohnuma S., Development. October 1, 2015; 142 (19): 3351-61.                              

JmjC Domain-containing Protein 6 (Jmjd6) Derepresses the Transcriptional Repressor Transcription Factor 7-like 1 (Tcf7l1) and Is Required for Body Axis Patterning during Xenopus Embryogenesis., Zhang X, Gao Y, Lu L, Zhang Z, Zhang Z, Gan S, Xu L, Lei A, Cao Y, Cao Y., J Biol Chem. August 14, 2015; 290 (33): 20273-83.                      

Xenopus Pkdcc1 and Pkdcc2 Are Two New Tyrosine Kinases Involved in the Regulation of JNK Dependent Wnt/PCP Signaling Pathway., Vitorino M, Silva AC, Inácio JM, Ramalho JS, Gur M, Fainsod A, Steinbeisser H, Belo JA., PLoS One. August 13, 2015; 10 (8): e0135504.                                    

Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin., Lu L, Gao Y, Zhang Z, Cao Q, Zhang X, Zou J, Cao Y., Dev Cell. June 22, 2015; 33 (6): 660-74.                                  

A time space translation hypothesis for vertebrate axial patterning., Durston AJ, Zhu K., Semin Cell Dev Biol. June 1, 2015; 42 86-93.  

Early neural ectodermal genes are activated by Siamois and Twin during blastula stages., Klein SL, Moody SA., Genesis. May 1, 2015; 53 (5): 308-20.          

cnrip1 is a regulator of eye and neural development in Xenopus laevis., Zheng X, Suzuki T, Takahashi C, Nishida E, Kusakabe M., Genes Cells. April 1, 2015; 20 (4): 324-39.                          

Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation., Zhang X, Cheong SM, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X., Dev Cell. March 23, 2015; 32 (6): 719-30.                                  

The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Acosta H, Iliev D, Grahn TH, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM., Development. March 15, 2015; 142 (6): 1146-58.                                    

Endogenous gradients of resting potential instructively pattern embryonic neural tissue via Notch signaling and regulation of proliferation., Pai VP, Lemire JM, Paré JF, Lin G, Chen Y, Levin M., J Neurosci. March 11, 2015; 35 (10): 4366-85.                    

Efficient retina formation requires suppression of both Activin and BMP signaling pathways in pluripotent cells., Wong KA, Trembley M, Abd Wahab S, Viczian AS., Biol Open. March 6, 2015; 4 (4): 573-83.                

E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation., Wills AE, Baker JC., Dev Cell. February 9, 2015; 32 (3): 345-57.                  

COUP-TFs and eye development., Tang K, Tsai SY, Tsai MJ., Biochim Biophys Acta. February 1, 2015; 1849 (2): 201-9.    

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism., Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M., Sci Rep. January 12, 2015; 5 11603.                                  

Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites., Kim YJ, Bahn M, Kim YH, Shin JY, Cheong SW, Ju BG, Kim WS, Yeo CY., Dev Biol. January 1, 2015; 397 (1): 129-39.                                          

Temporal and spatial expression analysis of peripheral myelin protein 22 (Pmp22) in developing Xenopus., Tae HJ, Rahman MM, Park BY., Gene Expr Patterns. January 1, 2015; 17 (1): 26-30.              

Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG, Predes D, Fonseca BF, Cerqueira DM, Reis AH, Dudenhoeffer AC, Borges HL, Mendes FA, Abreu JG., J Biol Chem. December 19, 2014; 289 (51): 35456-67.                  

PV.1 induced by FGF-Xbra functions as a repressor of neurogenesis in Xenopus embryos., Yoon J, Kim JH, Lee SY, Kim S, Park JB, Lee JY, Kim J., BMB Rep. December 1, 2014; 47 (12): 673-8.        

Genome-wide view of TGFβ/Foxh1 regulation of the early mesendoderm program., Chiu WT, Charney Le R, Blitz IL, Fish MB, Li Y, Biesinger J, Xie X, Cho KW., Development. December 1, 2014; 141 (23): 4537-47.                                  

Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development., Zhang S, Li J, Lea R, Vleminckx K, Vleminckx K, Amaya E., Development. December 1, 2014; 141 (24): 4794-805.                            

The conserved barH-like homeobox-2 gene barhl2 acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal forebrain signaling center induced by Sonic Hedgehog., Juraver-Geslin HA, Gómez-Skarmeta JL, Durand BC., Dev Biol. December 1, 2014; 396 (1): 107-20.                    

Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character., Fish MB, Nakayama T, Fisher M, Hirsch N, Cox A, Reeder R, Carruthers S, Hall A, Stemple DL, Grainger RM., Dev Biol. November 15, 2014; 395 (2): 317-330.                  

Developmental enhancers are marked independently of zygotic Nodal signals in Xenopus., Gupta R, Wills A, Ucar D, Baker J., Dev Biol. November 1, 2014; 395 (1): 38-49.            

Custos controls β-catenin to regulate head development during vertebrate embryogenesis., Komiya Y, Mandrekar N, Sato A, Dawid IB, Habas R., Proc Natl Acad Sci U S A. September 9, 2014; 111 (36): 13099-104.                                

Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification., Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M., Nat Commun. July 9, 2014; 5 4322.        

Fgfr signaling is required as the early eye field forms to promote later patterning and morphogenesis of the eye., Atkinson-Leadbeater K, Hehr CL, McFarlane S., Dev Dyn. May 1, 2014; .              

Setting appropriate boundaries: fate, patterning and competence at the neural plate border., Groves AK, LaBonne C., Dev Biol. May 1, 2014; 389 (1): 2-12.    

Sp8 regulates inner ear development., Chung HA, Medina-Ruiz S, Harland RM., Proc Natl Acad Sci U S A. April 29, 2014; 111 (17): 6329-34.                                                    

Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus., Young JJ, Kjolby RA, Kong NR, Monica SD, Harland RM., Development. April 1, 2014; 141 (8): 1683-93.                                                                

Ras-dva1 small GTPase regulates telencephalon development in Xenopus laevis embryos by controlling Fgf8 and Agr signaling at the anterior border of the neural plate., Tereshina MB, Ermakova GV, Ivanova AS, Zaraisky AG., Biol Open. March 15, 2014; 3 (3): 192-203.                        

Wiring the retinal circuits activated by light during early development., Bertolesi GE, Hehr CL, McFarlane S., Neural Dev. February 13, 2014; 9 3.              

An essential role for LPA signalling in telencephalon development., Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L., Development. February 1, 2014; 141 (4): 940-9.                            

Inference of the Xenopus tropicalis embryonic regulatory network and spatial gene expression patterns., Zheng Z, Christley S, Chiu WT, Blitz IL, Xie X, Cho KW, Nie Q., BMC Syst Biol. January 8, 2014; 8 3.                  

FoxA4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos., Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL., PLoS One. January 1, 2014; 9 (10): e110559.                              

Zygotic expression of Exostosin1 (Ext1) is required for BMP signaling and establishment of dorsal-ventral pattern in Xenopus., Shieh YE, Wells DE, Sater AK., Int J Dev Biol. January 1, 2014; 58 (1): 27-34.          

The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins., Li HY, Grifone R, Saquet A, Carron C, Shi DL., Development. December 1, 2013; 140 (24): 4903-13.                                

Role of Sp5 as an essential early regulator of neural crest specification in xenopus., Park DS, Seo JH, Hong M, Bang W, Han JK, Choi SC., Dev Dyn. December 1, 2013; 242 (12): 1382-94.                

Expression and functional characterization of Xhmg-at-hook genes in Xenopus laevis., Macrì S, Sgarra R, Ros G, Maurizio E, Zammitti S, Milani O, Onorati M, Vignali R, Manfioletti G., PLoS One. July 1, 2013; 8 (7): e69866.              

sox4 and sox11 function during Xenopus laevis eye development., Cizelsky W, Hempel A, Metzig M, Tao S, Hollemann T, Kühl M, Kühl SJ., PLoS One. July 1, 2013; 8 (7): e69372.              

Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head., Cases O, Perea-Gomez A, Aguiar DP, Nykjaer A, Amsellem S, Chandellier J, Umbhauer M, Cereghini S, Madsen M, Collignon J, Verroust P, Riou JF, Creuzet SE, Kozyraki R., J Biol Chem. June 7, 2013; 288 (23): 16655-16670.    

Scaling of dorsal-ventral patterning by embryo size-dependent degradation of Spemann's organizer signals., Inomata H, Shibata T, Haraguchi T, Sasai Y., Cell. June 6, 2013; 153 (6): 1296-311.                      

BMP signal attenuates FGF pathway in anteroposterior neural patterning., Cho GS, Choi SC, Han JK., Biochem Biophys Res Commun. May 10, 2013; 434 (3): 509-15.        

Regulation of primitive hematopoiesis by class I histone deacetylases., Shah RR, Koniski A, Shinde M, Blythe SA, Fass DM, Haggarty SJ, Palis J, Klein PS., Dev Dyn. February 1, 2013; 242 (2): 108-21.              

The Xenopus doublesex-related gene Dmrt5 is required for olfactory placode neurogenesis., Parlier D, Moers V, Van Campenhout C, Preillon J, Leclère L, Saulnier A, Sirakov M, Busengdal H, Kricha S, Marine JC, Rentzsch F, Bellefroid EJ., Dev Biol. January 1, 2013; 373 (1): 39-52.                              

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