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Summary Expression Phenotypes Gene Literature (550) GO Terms (6) Nucleotides (309) Proteins (58) Interactants (2147) Wiki
XB--485219

Papers associated with otx2



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Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites., Kim YJ, Bahn M, Kim YH, Shin JY, Cheong SW, Ju BG, Kim WS, Yeo CY., Dev Biol. January 1, 2015; 397 (1): 129-39.                                          


Temporal and spatial expression analysis of peripheral myelin protein 22 (Pmp22) in developing Xenopus., Tae HJ, Rahman MM, Park BY., Gene Expr Patterns. January 1, 2015; 17 (1): 26-30.              


Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG, Predes D, Fonseca BF, Cerqueira DM, Reis AH, Dudenhoeffer AC, Borges HL, Mendes FA, Abreu JG., J Biol Chem. December 19, 2014; 289 (51): 35456-67.                  


PV.1 induced by FGF-Xbra functions as a repressor of neurogenesis in Xenopus embryos., Yoon J, Kim JH, Lee SY, Kim S, Park JB, Lee JY, Kim J., BMB Rep. December 1, 2014; 47 (12): 673-8.        


Genome-wide view of TGFβ/Foxh1 regulation of the early mesendoderm program., Chiu WT, Charney Le R, Blitz IL, Fish MB, Li Y, Biesinger J, Xie X, Cho KW., Development. December 1, 2014; 141 (23): 4537-47.                                  


Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development., Zhang S, Li J, Lea R, Vleminckx K, Vleminckx K, Amaya E., Development. December 1, 2014; 141 (24): 4794-805.                            


The conserved barH-like homeobox-2 gene barhl2 acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal forebrain signaling center induced by Sonic Hedgehog., Juraver-Geslin HA, Gómez-Skarmeta JL, Durand BC., Dev Biol. December 1, 2014; 396 (1): 107-20.                    


Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character., Fish MB, Nakayama T, Fisher M, Hirsch N, Cox A, Reeder R, Carruthers S, Hall A, Stemple DL, Grainger RM., Dev Biol. November 15, 2014; 395 (2): 317-330.                  


Developmental enhancers are marked independently of zygotic Nodal signals in Xenopus., Gupta R, Wills A, Ucar D, Baker J., Dev Biol. November 1, 2014; 395 (1): 38-49.            


Custos controls β-catenin to regulate head development during vertebrate embryogenesis., Komiya Y, Mandrekar N, Sato A, Dawid IB, Habas R., Proc Natl Acad Sci U S A. September 9, 2014; 111 (36): 13099-104.                                


Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification., Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M., Nat Commun. July 9, 2014; 5 4322.        


Fgfr signaling is required as the early eye field forms to promote later patterning and morphogenesis of the eye., Atkinson-Leadbeater K, Hehr CL, McFarlane S., Dev Dyn. May 1, 2014; .              


Setting appropriate boundaries: fate, patterning and competence at the neural plate border., Groves AK, LaBonne C., Dev Biol. May 1, 2014; 389 (1): 2-12.    


Sp8 regulates inner ear development., Chung HA, Medina-Ruiz S, Harland RM., Proc Natl Acad Sci U S A. April 29, 2014; 111 (17): 6329-34.                                                    


Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus., Young JJ, Kjolby RA, Kong NR, Monica SD, Harland RM., Development. April 1, 2014; 141 (8): 1683-93.                                                                


Ras-dva1 small GTPase regulates telencephalon development in Xenopus laevis embryos by controlling Fgf8 and Agr signaling at the anterior border of the neural plate., Tereshina MB, Ermakova GV, Ivanova AS, Zaraisky AG., Biol Open. March 15, 2014; 3 (3): 192-203.                        


Wiring the retinal circuits activated by light during early development., Bertolesi GE, Hehr CL, McFarlane S., Neural Dev. February 13, 2014; 9 3.              


An essential role for LPA signalling in telencephalon development., Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L., Development. February 1, 2014; 141 (4): 940-9.                            


Inference of the Xenopus tropicalis embryonic regulatory network and spatial gene expression patterns., Zheng Z, Christley S, Chiu WT, Blitz IL, Xie X, Cho KW, Nie Q., BMC Syst Biol. January 8, 2014; 8 3.                  


FoxA4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos., Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL., PLoS One. January 1, 2014; 9 (10): e110559.                              


Zygotic expression of Exostosin1 (Ext1) is required for BMP signaling and establishment of dorsal-ventral pattern in Xenopus., Shieh YE, Wells DE, Sater AK., Int J Dev Biol. January 1, 2014; 58 (1): 27-34.          


The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins., Li HY, Grifone R, Saquet A, Carron C, Shi DL., Development. December 1, 2013; 140 (24): 4903-13.                                


Role of Sp5 as an essential early regulator of neural crest specification in xenopus., Park DS, Seo JH, Hong M, Bang W, Han JK, Choi SC., Dev Dyn. December 1, 2013; 242 (12): 1382-94.                


Expression and functional characterization of Xhmg-at-hook genes in Xenopus laevis., Macrì S, Sgarra R, Ros G, Maurizio E, Zammitti S, Milani O, Onorati M, Vignali R, Manfioletti G., PLoS One. July 1, 2013; 8 (7): e69866.              


sox4 and sox11 function during Xenopus laevis eye development., Cizelsky W, Hempel A, Metzig M, Tao S, Hollemann T, Kühl M, Kühl SJ., PLoS One. July 1, 2013; 8 (7): e69372.              


Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head., Cases O, Perea-Gomez A, Aguiar DP, Nykjaer A, Amsellem S, Chandellier J, Umbhauer M, Cereghini S, Madsen M, Collignon J, Verroust P, Riou JF, Creuzet SE, Kozyraki R., J Biol Chem. June 7, 2013; 288 (23): 16655-16670.    


Scaling of dorsal-ventral patterning by embryo size-dependent degradation of Spemann's organizer signals., Inomata H, Shibata T, Haraguchi T, Sasai Y., Cell. June 6, 2013; 153 (6): 1296-311.                      


BMP signal attenuates FGF pathway in anteroposterior neural patterning., Cho GS, Choi SC, Han JK., Biochem Biophys Res Commun. May 10, 2013; 434 (3): 509-15.        


Regulation of primitive hematopoiesis by class I histone deacetylases., Shah RR, Koniski A, Shinde M, Blythe SA, Fass DM, Haggarty SJ, Palis J, Klein PS., Dev Dyn. February 1, 2013; 242 (2): 108-21.              


The Xenopus doublesex-related gene Dmrt5 is required for olfactory placode neurogenesis., Parlier D, Moers V, Van Campenhout C, Preillon J, Leclère L, Saulnier A, Sirakov M, Busengdal H, Kricha S, Marine JC, Rentzsch F, Bellefroid EJ., Dev Biol. January 1, 2013; 373 (1): 39-52.                              


An intact brachyury function is necessary to prevent spurious axial development in Xenopus laevis., Aguirre CE, Murgan S, Carrasco AE, López SL., PLoS One. January 1, 2013; 8 (1): e54777.                                      


Suv4-20h histone methyltransferases promote neuroectodermal differentiation by silencing the pluripotency-associated Oct-25 gene., Nicetto D, Hahn M, Jung J, Schneider TD, Straub T, David R, Schotta G, Rupp RA., PLoS Genet. January 1, 2013; 9 (1): e1003188.                                                                


Xnr3 affects brain patterning via cell migration in the neural-epidermal tissue boundary during early Xenopus embryogenesis., Morita M, Yamashita S, Matsukawa S, Haramoto Y, Takahashi S, Asashima M, Michiue T., Int J Dev Biol. January 1, 2013; 57 (9-10): 779-86.          


Identification and evolution of molecular domains involved in differentiating the cement gland-promoting activity of Otx proteins in Xenopus laevis., Mancini P, Castelli M, Vignali R., Mech Dev. January 1, 2013; 130 (11-12): 628-39.          


Signaling and transcriptional regulation in neural crest specification and migration: lessons from xenopus embryos., Pegoraro C, Monsoro-Burq AH., Wiley Interdiscip Rev Dev Biol. January 1, 2013; 2 (2): 247-59.      


AP-1(c-Jun/FosB) mediates xFoxD5b expression in Xenopus early developmental neurogenesis., Yoon J, Kim JH, Lee OJ, Lee SY, Lee SH, Park JB, Lee JY, Kim SC, Kim J., Int J Dev Biol. January 1, 2013; 57 (11-12): 865-72.        


Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development., Xu Y, Xu Y, Xu C, Kato A, Tempel W, Abreu JG, Bian C, Hu Y, Hu D, Zhao B, Cerovina T, Diao J, Wu F, He HH, Cui Q, Clark E, Ma C, Barbara A, Veenstra GJ, Xu G, Kaiser UB, Liu XS, Sugrue SP, He X, Min J, Kato Y, Shi YG., Cell. December 7, 2012; 151 (6): 1200-13.                


Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning., Steventon B, Mayor R, Streit A., Dev Biol. July 1, 2012; 367 (1): 55-65.                


A developmental requirement for HIRA-dependent H3.3 deposition revealed at gastrulation in Xenopus., Szenker E, Lacoste N, Almouzni G., Cell Rep. June 28, 2012; 1 (6): 730-40.                                      


Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation., Zhang X, Abreu JG, Yokota C, MacDonald BT, Singh S, Coburn KL, Cheong SM, Zhang MM, Ye QZ, Hang HC, Steen H, He X., Cell. June 22, 2012; 149 (7): 1565-77.                      


Plasma membrane cholesterol depletion disrupts prechordal plate and affects early forebrain patterning., Reis AH, Almeida-Coburn KL, Louza MP, Cerqueira DM, Aguiar DP, Silva-Cardoso L, Mendes FA, Andrade LR, Einicker-Lamas M, Atella GC, Brito JM, Abreu JG., Dev Biol. May 15, 2012; 365 (2): 350-62.                    


Dynamic in vivo binding of transcription factors to cis-regulatory modules of cer and gsc in the stepwise formation of the Spemann-Mangold organizer., Sudou N, Yamamoto S, Ogino H, Taira M., Development. May 1, 2012; 139 (9): 1651-61.                  


The cytoplasmic tyrosine kinase Arg regulates gastrulation via control of actin organization., Bonacci G, Fletcher J, Devani M, Dwivedi H, Keller R, Chang C., Dev Biol. April 1, 2012; 364 (1): 42-55.                                        


TAK1 promotes BMP4/Smad1 signaling via inhibition of erk MAPK: a new link in the FGF/BMP regulatory network., Liu C, Goswami M, Talley J, Chesser-Martinez PL, Lou CH, Sater AK., Differentiation. April 1, 2012; 83 (4): 210-9.                  


Short chain dehydrogenase/reductase rdhe2 is a novel retinol dehydrogenase essential for frog embryonic development., Belyaeva OV, Lee SA, Adams MK, Chang C, Kedishvili NY., J Biol Chem. March 16, 2012; 287 (12): 9061-71.              


The RNA-binding protein XSeb4R regulates maternal Sox3 at the posttranscriptional level during maternal-zygotic transition in Xenopus., Bentaya S, Ghogomu SM, Vanhomwegen J, Van Campenhout C, Thelie A, Dhainaut M, Bellefroid EJ, Souopgui J., Dev Biol. March 15, 2012; 363 (2): 362-72.                      


Transcription factors involved in lens development from the preplacodal ectoderm., Ogino H, Ochi H, Reza HM, Yasuda K., Dev Biol. March 15, 2012; 363 (2): 333-47.      


Roles of ADAM13-regulated Wnt activity in early Xenopus eye development., Wei S, Xu G, Bridges LC, Williams P, Nakayama T, Shah A, Grainger RM, White JM, DeSimone DW., Dev Biol. March 1, 2012; 363 (1): 147-54.                          


Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis., Pai VP, Aw S, Shomrat T, Lemire JM, Levin M., Development. January 1, 2012; 139 (2): 313-23.                


Maternal xNorrin, a canonical Wnt signaling agonist and TGF-β antagonist, controls early neuroectoderm specification in Xenopus., Xu S, Cheng F, Liang J, Wu W, Zhang J., PLoS Biol. January 1, 2012; 10 (3): e1001286.                                    

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