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4-hydroxy-1,2,5-oxadiazol-3-yl moiety as bioisoster of the carboxy function. Synthesis, ionization constants, and molecular pharmacological characterization at ionotropic glutamate receptors of compounds related to glutamate and its homologues. , Lolli ML, Giordano C, Pickering DS, Rolando B, Hansen KB, Foti A, Contreras-Sanz A, Amir A, Fruttero R, Gasco A, Nielsen B, Johansen TN., J Med Chem. May 27, 2010; 53 (10): 4110-8.
B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo. , Okuda Y, Ogura E, Kondoh H, Kamachi Y., PLoS Genet. May 6, 2010; 6 (5): e1000936.
The nodal inhibitor Coco is a critical target of leftward flow in Xenopus. , Schweickert A , Vick P , Getwan M , Weber T , Schneider I, Eberhardt M, Beyer T, Pachur A, Blum M ., Curr Biol. April 27, 2010; 20 (8): 738-43.
BCL6 canalizes Notch-dependent transcription, excluding Mastermind-like1 from selected target genes during left- right patterning. , Sakano D, Kato A, Parikh N, McKnight K, Terry D, Stefanovic B, Kato Y ., Dev Cell. March 16, 2010; 18 (3): 450-62.
Structural determinants of D-cycloserine efficacy at the NR1/ NR2C NMDA receptors. , Dravid SM, Burger PB, Prakash A, Geballe MT, Yadav R, Le P, Vellano K, Snyder JP, Traynelis SF., J Neurosci. February 17, 2010; 30 (7): 2741-54.
Planar cell polarity enables posterior localization of nodal cilia and left- right axis determination during mouse and Xenopus embryogenesis. , Antic D, Stubbs JL, Suyama K, Kintner C , Scott MP, Axelrod JD., PLoS One. February 2, 2010; 5 (2): e8999.
Tissue- Tissue Interaction-Triggered Calcium Elevation Is Required for Cell Polarization during Xenopus Gastrulation. , Shindo A, Hara Y, Yamamoto TS , Ohkura M, Nakai J, Ueno N ., PLoS One. February 2, 2010; 5 (2): e8897.
Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway. , Luxardi G , Marchal L, Thomé V, Kodjabachian L ., Development. February 1, 2010; 137 (3): 417-26.
Repression of zygotic gene expression in the Xenopus germline. , Venkatarama T, Lai F , Luo X, Zhou Y, Newman K, King ML ., Development. February 1, 2010; 137 (4): 651-60.
A protocadherin-cadherin- FLRT3 complex controls cell adhesion and morphogenesis. , Chen X, Koh E, Yoder M , Gumbiner BM ., PLoS One. December 22, 2009; 4 (12): e8411.
Early activation of FGF and nodal pathways mediates cardiac specification independently of Wnt/beta-catenin signaling. , Samuel LJ, Latinkić BV., PLoS One. October 28, 2009; 4 (10): e7650.
Molecular and functional characterization of Xenopus laevis N-methyl-d-aspartate receptors. , Schmidt C, Hollmann M., Mol Cell Neurosci. October 1, 2009; 42 (2): 116-27.
Membrane trauma and Na+ leak from Nav1.6 channels. , Wang JA , Lin W, Morris T, Banderali U, Juranka PF, Morris CE., Am J Physiol Cell Physiol. October 1, 2009; 297 (4): C823-34.
Molecular insights into evolution of the vertebrate gut: focus on stomach and parietal cells in the marsupial, Macropus eugenii. , Kwek J, De Iongh R, Nicholas K, Familari M., J Exp Zool B Mol Dev Evol. September 15, 2009; 312 (6): 613-24.
Cloning and Phylogenetic Analysis of NMDA Receptor Subunits NR1, NR2A and NR2B in Xenopus laevis Tadpoles. , Ewald RC, Cline HT ., Front Mol Neurosci. September 11, 2009; 2 4.
Bistability in a model of mesoderm and anterior mesendoderm specification in Xenopus laevis. , Middleton AM, King JR, Loose M., J Theor Biol. September 7, 2009; 260 (1): 41-55.
Rab5-mediated endocytosis of activin is not required for gene activation or long-range signalling in Xenopus. , Hagemann AI, Xu X, Nentwich O, Hyvonen M, Smith JC ., Development. August 1, 2009; 136 (16): 2803-13.
Unexpected functional redundancy between Twist and Slug ( Snail2) and their feedback regulation of NF-kappaB via Nodal and Cerberus. , Zhang C, Klymkowsky MW ., Dev Biol. July 15, 2009; 331 (2): 340-9.
Flow on the right side of the gastrocoel roof plate is dispensable for symmetry breakage in the frog Xenopus laevis. , Vick P , Schweickert A , Weber T , Eberhardt M, Mencl S, Shcherbakov D, Beyer T, Blum M ., Dev Biol. July 15, 2009; 331 (2): 281-91.
Tumor necrosis factor-receptor-associated factor-4 is a positive regulator of transforming growth factor-beta signaling that affects neural crest formation. , Kalkan T, Iwasaki Y , Park CY, Thomsen GH ., Mol Biol Cell. July 1, 2009; 20 (14): 3436-50.
Riding shotgun: a dual role for the epidermal growth factor- Cripto/ FRL-1/Cryptic protein Cripto in Nodal trafficking. , Constam DB., Traffic. July 1, 2009; 10 (7): 783-91.
Identification of a novel negative regulator of activin/ nodal signaling in mesendodermal formation of Xenopus embryos. , Cheong SM, Kim H , Han JK ., J Biol Chem. June 19, 2009; 284 (25): 17052-60.
Xenopus, an ideal model system to study vertebrate left- right asymmetry. , Blum M , Beyer T, Weber T, Vick P , Andre P, Bitzer E, Schweickert A ., Dev Dyn. June 1, 2009; 238 (6): 1215-25.
Chromatin immunoprecipitation in early Xenopus laevis embryos. , Blythe SA , Reid CD, Kessler DS , Klein PS ., Dev Dyn. June 1, 2009; 238 (6): 1422-32.
Evolution of leftward flow. , Blum M , Weber T, Beyer T, Vick P ., Semin Cell Dev Biol. June 1, 2009; 20 (4): 464-71.
Effects of NR1 splicing on NR1/NR3B-type excitatory glycine receptors. , Cavara NA, Orth A, Hollmann M., BMC Neurosci. April 6, 2009; 10 32.
The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection. , Rosa A, Spagnoli FM , Brivanlou AH ., Dev Cell. April 1, 2009; 16 (4): 517-27.
Pharmacological characterization of recombinant NR1/ NR2A NMDA receptors with truncated and deleted carboxy termini expressed in Xenopus laevis oocytes. , Puddifoot CA, Chen PE, Schoepfer R, Wyllie DJ., Br J Pharmacol. February 1, 2009; 156 (3): 509-18.
R-spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis Kazanskaya O, Glinka A, del BarcoBarrantes I, Stannek P, Niehrs C, Wu W, Division of Molecular Embryology, Deutsches Krebsforschungszentrum, Heidelberg, Germany. , Koeneman KS., Urol Oncol. January 1, 2009; 27 (1):
GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses. , Levine AJ, Levine ZJ, Brivanlou AH ., Dev Biol. January 1, 2009; 325 (1): 43-8.
Molecular determinants of multiple effects of nickel on NMDA receptor channels. , Gavazzo P, Guida P, Zanardi I, Marchetti C., Neurotox Res. January 1, 2009; 15 (1): 38-48.
Oct25 represses transcription of nodal/activin target genes by interaction with signal transducers during Xenopus gastrulation. , Cao Y , Siegel D , Oswald F, Knöchel W ., J Biol Chem. December 5, 2008; 283 (49): 34168-77.
Left-asymmetric expression of Galanin in the linear heart tube of the mouse embryo is independent of the nodal co-receptor gene cryptic. , Schweickert A , Deissler K, Britsch S, Albrecht M, Ehmann H, Mauch V, Gaio U, Blum M ., Dev Dyn. December 1, 2008; 237 (12): 3557-64.
Maternal Tgif1 regulates nodal gene expression in Xenopus. , Kerr TC, Cuykendall TN , Luettjohann LC, Houston DW ., Dev Dyn. October 1, 2008; 237 (10): 2862-73.
Different structural requirements for functional ion pore transplantation suggest different gating mechanisms of NMDA and kainate receptors. , Villmann C, Hoffmann J, Werner M, Kott S, Strutz-Seebohm N, Nilsson T, Hollmann M., J Neurochem. October 1, 2008; 107 (2): 453-65.
NIP6;1 is a boric acid channel for preferential transport of boron to growing shoot tissues in Arabidopsis. , Tanaka M, Wallace IS, Takano J, Roberts DM, Fujiwara T., Plant Cell. October 1, 2008; 20 (10): 2860-75.
Rules of engagement for NMDA receptor subunits. , Ulbrich MH, Isacoff EY., Proc Natl Acad Sci U S A. September 16, 2008; 105 (37): 14163-8.
Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/ Nodal signalling. , Batut J, Schmierer B, Cao J, Raftery LA, Hill CS , Howell M., Development. September 1, 2008; 135 (17): 2927-37.
Supralinear potentiation of NR1/ NR3A excitatory glycine receptors by Zn2+ and NR1 antagonist. , Madry C, Betz H, Geiger JR, Laube B., Proc Natl Acad Sci U S A. August 26, 2008; 105 (34): 12563-8.
The NR1 M3 domain mediates allosteric coupling in the N-methyl-D-aspartate receptor. , Blanke ML, VanDongen AM., Mol Pharmacol. August 1, 2008; 74 (2): 454-65.
The pro-domain of the zebrafish Nodal-related protein Cyclops regulates its signaling activities. , Tian J , Andrée B, Jones CM , Sampath K ., Development. August 1, 2008; 135 (15): 2649-58.
Constitutive activation of the N-methyl-D-aspartate receptor via cleft-spanning disulfide bonds. , Blanke ML, VanDongen AM., J Biol Chem. August 1, 2008; 283 (31): 21519-29.
Differential effects of linear and cyclic polyamines on NMDA receptor activities. , Masuko T, Miyake M, Kusama-Eguchi K, Koike T, Kimura E, Kizawa Y, Kashiwagi K , Igarashi K, Kusama T., Neurochem Int. July 1, 2008; 53 (1-2): 38-44.
Regulation of activin/ nodal signaling by Rap2-directed receptor trafficking. , Choi SC, Kim GH , Lee SJ, Park E, Yeo CY, Han JK ., Dev Cell. July 1, 2008; 15 (1): 49-61.
Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3. , Maretto S, Müller PS, Aricescu AR, Cho KW , Bikoff EK, Robertson EJ., Dev Biol. June 1, 2008; 318 (1): 184-93.
Molecular determinants of the anticonvulsant felbamate binding site in the N-methyl-D-aspartate receptor. , Chang HR, Kuo CC., J Med Chem. March 27, 2008; 51 (6): 1534-45.
Long- and short-range signals control the dynamic expression of an animal hemisphere-specific gene in Xenopus. , Mir A, Kofron M , Heasman J , Mogle M, Lang S, Birsoy B, Wylie C ., Dev Biol. March 1, 2008; 315 (1): 161-72.
Activin/ nodal signaling modulates XPAPC expression during Xenopus gastrulation. , Lou X, Li S, Wang J , Ding X., Dev Dyn. March 1, 2008; 237 (3): 683-91.
A perchlorate sensitive iodide transporter in frogs. , Carr DL, Carr JA, Willis RE, Pressley TA., Gen Comp Endocrinol. March 1, 2008; 156 (1): 9-14.
Apparent homomeric NR1 currents observed in Xenopus oocytes are caused by an endogenous NR2 subunit. , Schmidt C, Hollmann M., J Mol Biol. February 22, 2008; 376 (3): 658-70.