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Summary Expression Phenotypes Gene Literature (274) GO Terms (17) Nucleotides (1482) Proteins (65) Interactants (654) Wiki
XB--489467

Papers associated with ran



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Systematic screening for genes specifically expressed in the anterior neuroectoderm during early Xenopus development., Takahashi N, Tochimoto N, Ohmori SY, Mamada H, Itoh M, Inamori M, Shinga J, Osada S, Taira M., Int J Dev Biol. January 1, 2005; 49 (8): 939-51.                                    

Bipolarization and poleward flux correlate during Xenopus extract spindle assembly., Mitchison TJ, Maddox P, Groen A, Cameron L, Perlman Z, Ohi R, Desai A, Salmon ED, Kapoor TM., Mol Biol Cell. December 1, 2004; 15 (12): 5603-15.

Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts., Brunet S, Sardon T, Zimmerman T, Wittmann T, Pepperkok R, Karsenti E, Vernos I., Mol Biol Cell. December 1, 2004; 15 (12): 5318-28.

XRHAMM functions in ran-dependent microtubule nucleation and pole formation during anastral spindle assembly., Groen AC, Cameron LA, Coughlin M, Miyamoto DT, Mitchison TJ, Ohi R., Curr Biol. October 26, 2004; 14 (20): 1801-11.            

Mitosis-specific anchoring of gamma tubulin complexes by pericentrin controls spindle organization and mitotic entry., Zimmerman WC, Sillibourne J, Rosa J, Doxsey SJ., Mol Biol Cell. August 1, 2004; 15 (8): 3642-57.

The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly., Sampath SC, Ohi R, Leismann O, Salic A, Pozniakovski A, Funabiki H., Cell. July 23, 2004; 118 (2): 187-202.

Phosphorylation regulates the dynamic interaction of RCC1 with chromosomes during mitosis., Hutchins JR, Moore WJ, Hood FE, Wilson JS, Andrews PD, Swedlow JR, Clarke PR., Curr Biol. June 22, 2004; 14 (12): 1099-104.

Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells., Li HY, Zheng Y., Genes Dev. March 1, 2004; 18 (5): 512-27.

Nuclear export of microRNA precursors., Lund E, Güttinger S, Calado A, Dahlberg JE, Kutay U., Science. January 2, 2004; 303 (5654): 95-8.

Spatial and temporal control of nuclear envelope assembly by Ran GTPase., Clarke PR, Zhang C., Symp Soc Exp Biol. January 1, 2004; (56): 193-204.

Importin alpha/beta and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal., Ems-McClung SC, Zheng Y, Walczak CE., Mol Biol Cell. January 1, 2004; 15 (1): 46-57.

Regulation of Aurora-A kinase on the mitotic spindle., Kufer TA, Nigg EA, Silljé HH., Chromosoma. December 1, 2003; 112 (4): 159-63.

Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation., Trieselmann N, Armstrong S, Rauw J, Wilde A., J Cell Sci. December 1, 2003; 116 (Pt 23): 4791-8.

Ran in the spindle checkpoint: a new function for a versatile GTPase., Li HY, Cao K, Zheng Y., Trends Cell Biol. November 1, 2003; 13 (11): 553-7.

Importin beta negatively regulates nuclear membrane fusion and nuclear pore complex assembly., Harel A, Chan RC, Lachish-Zalait A, Zimmerman E, Elbaum M, Forbes DJ., Mol Biol Cell. November 1, 2003; 14 (11): 4387-96.

Aurora A on the mitotic spindle is activated by the way it holds its partner., Glover DM., Mol Cell. October 1, 2003; 12 (4): 797-9.  

Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity., Keryer G, Di Fiore B, Celati C, Lechtreck KF, Mogensen M, Delouvee A, Lavia P, Bornens M, Tassin AM., Mol Biol Cell. October 1, 2003; 14 (10): 4260-71.

Mammalian RanBP1 regulates centrosome cohesion during mitosis., Di Fiore B, Ciciarello M, Mangiacasale R, Palena A, Tassin AM, Cundari E, Lavia P., J Cell Sci. August 15, 2003; 116 (Pt 16): 3399-411.

The quest for the holy "G" of chromosomal passengers., Burke DJ, Stukenberg PT., Dev Cell. August 1, 2003; 5 (2): 187-8.

The Ran GTPase regulates kinetochore function., Arnaoutov A, Dasso M., Dev Cell. July 1, 2003; 5 (1): 99-111.

The condensin complex is required for proper spindle assembly and chromosome segregation in Xenopus egg extracts., Wignall SM, Deehan R, Maresca TJ, Heald R., J Cell Biol. June 23, 2003; 161 (6): 1041-51.              

Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates., Trotta CR, Lund E, Kahan L, Johnson AW, Dahlberg JE., EMBO J. June 2, 2003; 22 (11): 2841-51.

A role for Ran-GTP and Crm1 in blocking re-replication., Yamaguchi R, Newport J., Cell. April 4, 2003; 113 (1): 115-25.

A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo., Li HY, Wirtz D, Zheng Y., J Cell Biol. March 3, 2003; 160 (5): 635-44.          

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly., Tsai MY, Wiese C, Cao K, Martin O, Donovan P, Ruderman J, Prigent C, Zheng Y., Nat Cell Biol. March 1, 2003; 5 (3): 242-8.

Exportin-5 mediates nuclear export of minihelix-containing RNAs., Gwizdek C, Ossareh-Nazari B, Brownawell AM, Doglio A, Bertrand E, Macara IG, Dargemont C., J Biol Chem. February 21, 2003; 278 (8): 5505-8.

The strategy for coupling the RanGTP gradient to nuclear protein export., Becskei A, Mattaj IW., Proc Natl Acad Sci U S A. February 18, 2003; 100 (4): 1717-22.

N-Glycosylation at two sites critically alters thiazide binding and activity of the rat thiazide-sensitive Na(+):Cl(-) cotransporter., Hoover RS, Poch E, Monroy A, Vázquez N, Nishio T, Gamba G, Hebert SC., J Am Soc Nephrol. February 1, 2003; 14 (2): 271-82.

Nuclear RanGTP is not required for targeting small nucleolar RNAs to the nucleolus., Narayanan A, Eifert J, Marfatia KA, Macara IG, Corbett AH, Terns RM, Terns MP., J Cell Sci. January 1, 2003; 116 (Pt 1): 177-86.

Chromosomal association of Ran during meiotic and mitotic divisions., Hinkle B, Slepchenko B, Rolls MM, Walther TC, Stein PA, Mehlmann LM, Ellenberg J, Terasaki M., J Cell Sci. December 1, 2002; 115 (Pt 23): 4685-93.

Differences in apparent pore sizes of low and high voltage-activated Ca2+ channels., Cataldi M, Perez-Reyes E, Tsien RW., J Biol Chem. November 29, 2002; 277 (48): 45969-76.

Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly., Zhang C, Goldberg MW, Goldberg MW, Moore WJ, Allen TD, Clarke PR., Eur J Cell Biol. November 1, 2002; 81 (11): 623-33.

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells., Gruss OJ, Wittmann M, Yokoyama H, Pepperkok R, Kufer T, Silljé H, Karsenti E, Mattaj IW, Vernos I., Nat Cell Biol. November 1, 2002; 4 (11): 871-9.

Sensitization by extracellular Ca(2+) of rat P2X(5) receptor and its pharmacological properties compared with rat P2X(1)., Wildman SS, Brown SG, Rahman M, Noel CA, Churchill L, Burnstock G, Unwin RJ, King BF., Mol Pharmacol. October 1, 2002; 62 (4): 957-66.

Reconstitution of nuclear protein export in isolated nuclear envelopes., Siebrasse JP, Coutavas E, Peters R., J Cell Biol. September 2, 2002; 158 (5): 849-54.          

Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells., Moore W, Zhang C, Clarke PR., Curr Biol. August 20, 2002; 12 (16): 1442-7.

Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains., Kuersten S, Arts GJ, Walther TC, Englmeier L, Mattaj IW., Mol Cell Biol. August 1, 2002; 22 (16): 5708-20.

Ran binds to chromatin by two distinct mechanisms., Bilbao-Cortés D, Hetzer M, Längst G, Becker PB, Mattaj IW., Curr Biol. July 9, 2002; 12 (13): 1151-6.

The C-terminal extension of the small GTPase Ran is essential for defining the GDP-bound form., Nilsson J, Weis K, Kjems J., J Mol Biol. April 26, 2002; 318 (2): 583-93.

Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts., Kalab P, Weis K, Heald R., Science. March 29, 2002; 295 (5564): 2452-6.

The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo., Bamba C, Bobinnec Y, Fukuda M, Nishida E., Curr Biol. March 19, 2002; 12 (6): 503-7.

Role of importin-beta in the control of nuclear envelope assembly by Ran., Zhang C, Hutchins JR, Mühlhäusser P, Kutay U, Clarke PR., Curr Biol. March 19, 2002; 12 (6): 498-502.

Induction of maturation-promoting factor during Xenopus oocyte maturation uncouples Ca(2+) store depletion from store-operated Ca(2+) entry., Machaca K, Haun S., J Cell Biol. January 7, 2002; 156 (1): 75-85.                

Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly., Hetzer M, Meyer HH, Walther TC, Bilbao-Cortes D, Warren G, Mattaj IW., Nat Cell Biol. December 1, 2001; 3 (12): 1086-91.

Cytosolic import factor- and Ran-independent nuclear transport of ribosomal protein L5., Rudt F, Pieler T., Eur J Cell Biol. November 1, 2001; 80 (11): 661-8.

A light microscope study of the distribution of muscle in the frog esophagus and stomach., Yoshida M., J Smooth Muscle Res. August 1, 2001; 37 (3-4): 95-104.

XMog1, a nuclear ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe mog1p that co-operates with RanBP1 to control generation of Ran-GTP., Nicolás FJ, Moore WJ, Zhang C, Clarke PR., J Cell Sci. August 1, 2001; 114 (Pt 16): 3013-23.

Ran binding protein RanBP1 in zebrafish embryonic development., Mangos S, Vanderbeld B, Krawetz R, Sudol K, Kelly GM., Mol Reprod Dev. July 1, 2001; 59 (3): 235-48.

Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B., Nemergut ME, Mizzen CA, Stukenberg T, Allis CD, Macara IG., Science. May 25, 2001; 292 (5521): 1540-3.

Ran GTPase cycle: oOne mechanism -- two functions., Melchior F., Curr Biol. April 3, 2001; 11 (7): R257-60.

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