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Summary Expression Phenotypes Gene Literature (341) GO Terms (30) Nucleotides (200) Proteins (40) Interactants (1190) Wiki
XB--1017460

Papers associated with dvl2



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The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo., Bryja V, Andersson ER, Schambony A, Esner M, Bryjová L, Biris KK, Hall AC, Kraft B, Cajanek L, Yamaguchi TP, Buckingham M, Arenas E., Mol Biol Cell. February 1, 2009; 20 (3): 924-36.        


Fibroblast growth factor receptor-induced phosphorylation of ephrinB1 modulates its interaction with Dishevelled., Lee HS, Mood K, Battu G, Ji YJ, Singh A, Daar IO., Mol Biol Cell. January 1, 2009; 20 (1): 124-33.                    


Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1., Louie SH, Yang XY, Conrad WH, Muster J, Angers S, Moon RT, Cheyette BN., PLoS One. January 1, 2009; 4 (2): e4310.                    


Interactions between Casein kinase Iepsilon (CKIepsilon) and two substrates from disparate signaling pathways reveal mechanisms for substrate-kinase specificity., Dahlberg CL, Nguyen EZ, Goodlett D, Kimelman D., PLoS One. January 1, 2009; 4 (3): e4766.                  


Sulindac inhibits canonical Wnt signaling by blocking the PDZ domain of the protein Dishevelled., Lee HJ, Wang NX, Shi DL, Zheng JJ., Angew Chem Int Ed Engl. January 1, 2009; 48 (35): 6448-52.


Contact inhibition of locomotion in vivo controls neural crest directional migration., Carmona-Fontaine C, Matthews HK, Kuriyama S, Moreno M, Dunn GA, Parsons M, Stern CD, Mayor R., Nature. December 18, 2008; 456 (7224): 957-61.      


PTK7 recruits dsh to regulate neural crest migration., Shnitsar I, Borchers A., Development. December 1, 2008; 135 (24): 4015-24.            


Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways., Bryja V, Schambony A, Cajánek L, Dominguez I, Arenas E, Schulte G., EMBO Rep. December 1, 2008; 9 (12): 1244-50.


Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling., Li Y, Rankin SA, Rankin SA, Sinner D, Kenny AP, Krieg PA, Zorn AM., Genes Dev. November 1, 2008; 22 (21): 3050-63.                        


Dishevelled links basal body docking and orientation in ciliated epithelial cells., Vladar EK, Axelrod JD., Trends Cell Biol. November 1, 2008; 18 (11): 517-20.


Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements., Kim GH, Her JH, Han JK., J Cell Biol. September 22, 2008; 182 (6): 1073-82.          


Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation., Pan W, Choi SC, Wang H, Qin Y, Volpicelli-Daley L, Swan L, Lucast L, Khoo C, Zhang X, Li L, Abrams CS, Sokol SY, Wu D., Science. September 5, 2008; 321 (5894): 1350-3.


Nucleoredoxin regulates the Wnt/planar cell polarity pathway in Xenopus., Funato Y, Michiue T, Terabayashi T, Yukita A, Danno H, Asashima M, Miki H., Genes Cells. September 1, 2008; 13 (9): 965-75.            


Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells., Park TJ, Mitchell BJ, Abitua PB, Kintner C, Wallingford JB., Nat Genet. July 1, 2008; 40 (7): 871-9.      


Binding of sFRP-3 to EGF in the extra-cellular space affects proliferation, differentiation and morphogenetic events regulated by the two molecules., Scardigli R, Gargioli C, Tosoni D, Borello U, Sampaolesi M, Sciorati C, Cannata S, Clementi E, Brunelli S, Cossu G., PLoS One. June 18, 2008; 3 (6): e2471.                    


Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA., Matthews HK, Marchant L, Carmona-Fontaine C, Kuriyama S, Larraín J, Holt MR, Parsons M, Mayor R., Development. May 1, 2008; 135 (10): 1771-80.                    


Apical accumulation of Rho in the neural plate is important for neural plate cell shape change and neural tube formation., Kinoshita N, Sasai N, Misaki K, Yonemura S., Mol Biol Cell. May 1, 2008; 19 (5): 2289-99.  


The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling., Luyten A, Mortier E, Van Campenhout C, Taelman V, Degeest G, Wuytens G, Lambaerts K, David G, Bellefroid EJ, Zimmermann P., Mol Biol Cell. April 1, 2008; 19 (4): 1594-604.                  


WGEF activates Rho in the Wnt-PCP pathway and controls convergent extension in Xenopus gastrulation., Tanegashima K, Zhao H, Dawid IB., EMBO J. February 20, 2008; 27 (4): 606-17.


Coordination of cell polarity during Xenopus gastrulation., Shindo A, Yamamoto TS, Ueno N., PLoS One. February 6, 2008; 3 (2): e1600.              


Intracellular expression profiles measured by real-time PCR tomography in the Xenopus laevis oocyte., Sindelka R, Jonák J, Hands R, Bustin SA, Kubista M., Nucleic Acids Res. February 1, 2008; 36 (2): 387-92.        


Mechanism of activation of the Formin protein Daam1., Liu W, Sato A, Khadka D, Bharti R, Diaz H, Runnels LW, Habas R., Proc Natl Acad Sci U S A. January 8, 2008; 105 (1): 210-5.                


Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions., Zeng X, Huang H, Tamai K, Zhang X, Harada Y, Yokota C, Almeida K, Wang J, Doble B, Woodgett J, Wynshaw-Boris A, Hsieh JC, He X., Development. January 1, 2008; 135 (2): 367-75.


Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling., Piao S, Lee SH, Kim H, Yum S, Stamos JL, Xu Y, Xu Y, Lee SJ, Lee J, Lee J, Oh S, Han JK, Park BJ, Weis WI, Ha NC., PLoS One. January 1, 2008; 3 (12): e4046.          


Detection of planar polarity proteins in mammalian cochlea., Montcouquiol M, Jones JM, Sans N., Methods Mol Biol. January 1, 2008; 468 207-19.


Nitric oxide coordinates cell proliferation and cell movements during early development of Xenopus., Peunova N, Scheinker V, Ravi K, Enikolopov G., Cell Cycle. December 15, 2007; 6 (24): 3132-44.


Lrp6 is required for convergent extension during Xenopus gastrulation., Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E., Development. November 1, 2007; 134 (22): 4095-106.


XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathway., Lee RH, Iioka H, Ohashi M, Iemura S, Natsume T, Kinoshita N., EMBO J. August 8, 2007; 26 (15): 3592-606.


Wnt11 stimulation induces polarized accumulation of Dishevelled at apical adherens junctions through Frizzled7., Yamanaka H, Nishida E., Genes Cells. August 1, 2007; 12 (8): 961-7.


Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation., Haremaki T, Fraser ST, Kuo YM, Baron MH, Weinstein DC., Proc Natl Acad Sci U S A. July 17, 2007; 104 (29): 12029-34.                    


Retinoic acid-inducible G protein-coupled receptors bind to frizzled receptors and may activate non-canonical Wnt signaling., Harada Y, Yokota C, Habas R, Slusarski DC, He X., Biochem Biophys Res Commun. July 13, 2007; 358 (4): 968-75.        


Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly., Lu J, Meng W, Poy F, Maiti S, Goode BL, Eck MJ., J Mol Biol. June 22, 2007; 369 (5): 1258-69.


R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling., Wei Q, Yokota C, Semenov MV, Doble B, Woodgett J, He X., J Biol Chem. May 25, 2007; 282 (21): 15903-11.  


Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements., Kim GH, Han JK., EMBO J. May 16, 2007; 26 (10): 2513-26.


Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo., Bryja V, Gradl D, Schambony A, Arenas E, Schulte G., Proc Natl Acad Sci U S A. April 17, 2007; 104 (16): 6690-5.  


Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling., Yu A, Rual JF, Tamai K, Harada Y, Vidal M, He X, Kirchhausen T., Dev Cell. January 1, 2007; 12 (1): 129-41.


Neurotrophin receptor homolog (NRH1) proteins regulate mesoderm formation and apoptosis during early Xenopus development., Knapp D, Messenger N, Ahmed Rana A, Smith JC., Dev Biol. December 15, 2006; 300 (2): 554-69.                  


The emergence of pattern in embryogenesis: regulation of beta-catenin localization during early sea urchin development., Ettensohn CA., Sci STKE. November 14, 2006; 2006 (361): pe48.


Profilin is an effector for Daam1 in non-canonical Wnt signaling and is required for vertebrate gastrulation., Sato A, Khadka DK, Liu W, Bharti R, Runnels LW, Dawid IB, Habas R., Development. November 1, 2006; 133 (21): 4219-31.  


Frodo links Dishevelled to the p120-catenin/Kaiso pathway: distinct catenin subfamilies promote Wnt signals., Park JI, Ji H, Jun S, Gu D, Hikasa H, Li L, Sokol SY, McCrea PD., Dev Cell. November 1, 2006; 11 (5): 683-95.


Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos., Liao G, Tao Q, Tao Q, Kofron M, Chen JS, Schloemer A, Davis RJ, Hsieh JC, Wylie C, Heasman J, Kuan CY., Proc Natl Acad Sci U S A. October 31, 2006; 103 (44): 16313-8.                    


Site-specific casein kinase 1epsilon-dependent phosphorylation of Dishevelled modulates beta-catenin signaling., Klimowski LK, Garcia BA, Shabanowitz J, Hunt DF, Virshup DM., FEBS J. October 1, 2006; 273 (20): 4594-602.


Metastasis-associated kinase modulates Wnt signaling to regulate brain patterning and morphogenesis., Kibardin A, Ossipova O, Sokol SY., Development. August 1, 2006; 133 (15): 2845-54.                    


The C/EBP homologous protein CHOP (GADD153) is an inhibitor of Wnt/TCF signals., Horndasch M, Lienkamp S, Springer E, Schmitt A, Pavenstädt H, Walz G, Gloy J., Oncogene. June 8, 2006; 25 (24): 3397-407.


Syndecan-4 regulates non-canonical Wnt signalling and is essential for convergent and extension movements in Xenopus embryos., Muñoz R, Moreno M, Oliva C, Orbenes C, Larraín J., Nat Cell Biol. May 1, 2006; 8 (5): 492-500.


The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled., Funato Y, Michiue T, Asashima M, Miki H., Nat Cell Biol. May 1, 2006; 8 (5): 501-8.


Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation., Wang J, Hamblet NS, Mark S, Dickinson ME, Brinkman BC, Segil N, Fraser SE, Chen P, Wallingford JB, Wynshaw-Boris A., Development. May 1, 2006; 133 (9): 1767-78.


Role of PKA as a negative regulator of PCP signaling pathway during Xenopus gastrulation movements., Park E, Kim GH, Choi SC, Han JK., Dev Biol. April 15, 2006; 292 (2): 344-57.


PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle., Creyghton MP, Roël G, Eichhorn PJ, Vredeveld LC, Destrée O, Bernards R., Proc Natl Acad Sci U S A. April 4, 2006; 103 (14): 5397-402.        


The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation., Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT., Nat Cell Biol. April 1, 2006; 8 (4): 348-57.

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