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Summary Expression Phenotypes Gene Literature (242) GO Terms (8) Nucleotides (225) Proteins (62) Interactants (1337) Wiki
XB--482929

Papers associated with smad2



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Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski., Takeda M, Mizuide M, Oka M, Watabe T, Inoue H, Suzuki H, Fujita T, Imamura T, Miyazono K, Miyazawa K., Mol Biol Cell. March 1, 2004; 15 (3): 963-72.                

Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors., Cheng SK, Olale F, Brivanlou AH, Schier AF., PLoS Biol. February 1, 2004; 2 (2): E30.                  

Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirects the neural fate of embryonic stem cells., Parisi S, D'Andrea D, Lago CT, Adamson ED, Persico MG, Minchiotti G., J Cell Biol. October 27, 2003; 163 (2): 303-14.                    

[The role of Smads and related transcription factors in the signal transduction of bone morphogenetic protein inducing bone formation]., Xu XL, Dai KR, Tang TT., Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. September 1, 2003; 17 (5): 359-62.

Evidence for antagonism of BMP-4 signals by MAP kinase during Xenopus axis determination and neural specification., Sater AK, El-Hodiri HM, Goswami M, Alexander TB, Al-Sheikh O, Etkin LD, Akif Uzman J., Differentiation. September 1, 2003; 71 (7): 434-44.                

Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads., Cordenonsi M, Dupont S, Maretto S, Insinga A, Imbriano C, Piccolo S., Cell. May 2, 2003; 113 (3): 301-14.  

Regulation of the rat follicle-stimulating hormone beta-subunit promoter by activin., Suszko MI, Lo DJ, Suh H, Camper SA, Woodruff TK., Mol Endocrinol. March 1, 2003; 17 (3): 318-32.

Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein., Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R., Int J Dev Biol. February 1, 2003; 47 (1): 15-29.                  

Stoichiometry of active smad-transcription factor complexes on DNA., Inman GJ, Hill CS., J Biol Chem. December 27, 2002; 277 (52): 51008-16.

Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis., Crump D, Werry K, Veldhoen N, Van Aggelen G, Helbing CC., Environ Health Perspect. December 1, 2002; 110 (12): 1199-205.

The nodal target gene Xmenf is a component of an FGF-independent pathway of ventral mesoderm induction in Xenopus., Kumano G, Smith WC., Mech Dev. October 1, 2002; 118 (1-2): 45-56.    

Molecular regulation of vertebrate early endoderm development., Shivdasani RA., Dev Biol. September 15, 2002; 249 (2): 191-203.      

The roles of three signaling pathways in the formation and function of the Spemann Organizer., Xanthos JB, Kofron M, Tao Q, Tao Q, Schaible K, Wylie C, Heasman J., Development. September 1, 2002; 129 (17): 4027-43.                  

A component of the ARC/Mediator complex required for TGF beta/Nodal signalling., Kato Y, Habas R, Katsuyama Y, Näär AM, He X., Nature. August 8, 2002; 418 (6898): 641-6.

Nuclear exclusion of Smad2 is a mechanism leading to loss of competence., Grimm OH, Gurdon JB., Nat Cell Biol. July 1, 2002; 4 (7): 519-22.

Phosphorylation regulation of the interaction between Smad7 and activin type I receptor., Liu X, Nagarajan RP, Vale W, Chen Y., FEBS Lett. May 22, 2002; 519 (1-3): 93-8.

A changing morphogen gradient is interpreted by continuous transduction flow., Bourillot PY, Garrett N, Gurdon JB., Development. May 1, 2002; 129 (9): 2167-80.

The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling., Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW., Genes Dev. April 1, 2002; 16 (7): 820-35.    

Action range of BMP is defined by its N-terminal basic amino acid core., Ohkawara B, Iemura S, ten Dijke P, Ueno N., Curr Biol. February 5, 2002; 12 (3): 205-9.          

Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif., Randall RA, Germain S, Inman GJ, Bates PA, Hill CS., EMBO J. January 15, 2002; 21 (1-2): 145-56.

Beta-catenin, MAPK and Smad signaling during early Xenopus development., Schohl A, Fagotto F., Development. January 1, 2002; 129 (1): 37-52.                                                                                                      

Loss of Smad4 function in pancreatic tumors: C-terminal truncation leads to decreased stability., Maurice D, Pierreux CE, Howell M, Wilentz RE, Owen MJ, Hill CS., J Biol Chem. November 16, 2001; 276 (46): 43175-81.

Expression cloning of Xenopus Os4, an evolutionarily conserved gene, which induces mesoderm and dorsal axis., Zohn IE, Brivanlou AH., Dev Biol. November 1, 2001; 239 (1): 118-31.                    

TGF-beta signalling pathways in early Xenopus development., Hill CS., Curr Opin Genet Dev. October 1, 2001; 11 (5): 533-40.    

Timing of endogenous activin-like signals and regional specification of the Xenopus embryo., Lee MA, Heasman J, Whitman M., Development. August 1, 2001; 128 (15): 2939-52.            

Xenopus Smad3 is specifically expressed in the chordoneural hinge, notochord and in the endocardium of the developing heart., Howell M, Mohun TJ, Hill CS., Mech Dev. June 1, 2001; 104 (1-2): 147-50.    

Swift is a novel BRCT domain coactivator of Smad2 in transforming growth factor beta signaling., Shimizu K, Bourillot PY, Nielsen SJ, Zorn AM, Gurdon JB., Mol Cell Biol. June 1, 2001; 21 (12): 3901-12.

Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms., Yeo C, Whitman M., Mol Cell. May 1, 2001; 7 (5): 949-57.

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase., Zhang Y, Zhang Y, Chang C, Gehling DJ, Hemmati-Brivanlou A, Derynck R., Proc Natl Acad Sci U S A. January 30, 2001; 98 (3): 974-9.        

Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads., Kumar A, Novoselov V, Celeste AJ, Wolfman NM, ten Dijke P, Kuehn MR., J Biol Chem. January 5, 2001; 276 (1): 656-61.

Calmodulin differentially modulates Smad1 and Smad2 signaling., Scherer A, Graff JM., J Biol Chem. December 29, 2000; 275 (52): 41430-8.

Recombinant expression and purification of smad proteins., Funaba M, Mathews LS., Protein Expr Purif. December 1, 2000; 20 (3): 507-13.

Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus., Pierreux CE, Nicolás FJ, Hill CS., Mol Cell Biol. December 1, 2000; 20 (23): 9041-54.

Vertebrate development: the fast track to nodal signalling., Stemple DL., Curr Biol. November 16, 2000; 10 (22): R843-6.

Mesendoderm induction and reversal of left-right pattern by mouse Gdf1, a Vg1-related gene., Wall NA, Craig EJ, Labosky PA, Kessler DS., Dev Biol. November 15, 2000; 227 (2): 495-509.              

Identification and characterization of constitutively active Smad2 mutants: evaluation of formation of Smad complex and subcellular distribution., Funaba M, Mathews LS., Mol Endocrinol. October 1, 2000; 14 (10): 1583-91.

Expression regulation of hyaluronan synthase in corneal endothelial cells., Usui T, Amano S, Oshika T, Suzuki K, Miyata K, Araie M, Heldin P, Yamashita H., Invest Ophthalmol Vis Sci. October 1, 2000; 41 (11): 3261-7.

Gli2 functions in FGF signaling during antero-posterior patterning., Brewster R, Mullor JL, Ruiz i Altaba A., Development. October 1, 2000; 127 (20): 4395-405.            

Fast1 is required for the development of dorsal axial structures in zebrafish., Sirotkin HI, Gates MA, Kelly PD, Schier AF, Talbot WS., Curr Biol. September 7, 2000; 10 (17): 1051-4.

Structural basis for the functional difference between Smad2 and Smad3 in FAST-2 (forkhead activin signal transducer-2)-mediated transcription., Nagarajan RP, Chen Y., Biochem J. August 15, 2000; 350 Pt 1 253-9.

A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction., Kim RH, Wang D, Tsang M, Martin J, Huff C, de Caestecker MP, Parks WT, Meng X, Lechleider RJ, Wang T, Roberts AB., Genes Dev. July 1, 2000; 14 (13): 1605-16.            

Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development., Faure S, Lee MA, Keller T, ten Dijke P, Whitman M., Development. July 1, 2000; 127 (13): 2917-31.      

Repression of transforming-growth-factor-beta-mediated transcription by nuclear factor kappaB., Nagarajan RP, Chen F, Li W, Vig E, Harrington MA, Nakshatri H, Chen Y., Biochem J. June 15, 2000; 348 Pt 3 591-6.

Activin A signaling directly activates Xenopus winged helix factors XFD-4/4', the orthologues to mammalian MFH-1., Köster M, Dillinger K, Knöchel W., Dev Genes Evol. June 1, 2000; 210 (6): 320-4.

Heterogeneities in the biological and biochemical functions of Smad2 and Smad4 mutants naturally occurring in human lung cancers., Yanagisawa K, Uchida K, Nagatake M, Masuda A, Sugiyama M, Saito T, Yamaki K, Takahashi T, Osada H., Oncogene. May 4, 2000; 19 (19): 2305-11.

Cloning and characterization of zebrafish smad2, smad3 and smad4., Dick A, Mayr T, Bauer H, Meier A, Hammerschmidt M., Gene. April 4, 2000; 246 (1-2): 69-80.

Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif., Germain S, Howell M, Esslemont GM, Hill CS., Genes Dev. February 15, 2000; 14 (4): 435-51.                

Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2., Saijoh Y, Adachi H, Sakuma R, Yeo CY, Yashiro K, Watanabe M, Hashiguchi H, Mochida K, Ohishi S, Kawabata M, Miyazono K, Whitman M, Hamada H., Mol Cell. January 1, 2000; 5 (1): 35-47.    

Activation of Stat3 by cytokine receptor gp130 ventralizes Xenopus embryos independent of BMP-4., Nishinakamura R, Matsumoto Y, Matsuda T, Ariizumi T, Heike T, Asashima M, Yokota T., Dev Biol. December 15, 1999; 216 (2): 481-90.              

FAST-1 is a key maternal effector of mesoderm inducers in the early Xenopus embryo., Watanabe M, Whitman M., Development. December 1, 1999; 126 (24): 5621-34.

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