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Summary Expression Phenotypes Gene Literature (234) GO Terms (11) Nucleotides (370) Proteins (50) Interactants (1557) Wiki
XB--484285

Papers associated with tp53



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Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads., Cordenonsi M, Dupont S, Maretto S, Insinga A, Imbriano C, Piccolo S., Cell. May 2, 2003; 113 (3): 301-14.  

p53 and TGF-beta in development: prelude to tumor suppression?, Whitman M, McKeon F., Cell. May 2, 2003; 113 (3): 275-6.

Change of conformation of the DNA-binding domain of p53 is the only key element for binding of and interference with p73., Bensaad K, Le Bras M, Unsal K, Strano S, Blandino G, Tominaga O, Rouillard D, Soussi T., J Biol Chem. March 21, 2003; 278 (12): 10546-55.

Deregulation of Cdc2 kinase induces caspase-3 activation and apoptosis., Gu L, Zheng H, Murray SA, Ying H, Jim Xiao ZX., Biochem Biophys Res Commun. March 7, 2003; 302 (2): 384-91.          

REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species., Ellisen LW, Ramsayer KD, Johannessen CM, Yang A, Beppu H, Minda K, Oliner JD, McKeon F, Haber DA., Mol Cell. November 1, 2002; 10 (5): 995-1005.

Having it both ways: transcription factors that bind DNA and RNA., Cassiday LA, Maher LJ., Nucleic Acids Res. October 1, 2002; 30 (19): 4118-26.

Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast., Blanchard F, Rusiniak ME, Sharma K, Sun X, Todorov I, Castellano MM, Gutierrez C, Baumann H, Burhans WC., Mol Biol Cell. May 1, 2002; 13 (5): 1536-49.

c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis., Furstoss O, Dorey K, Simon V, Barilà D, Superti-Furga G, Roche S., EMBO J. February 15, 2002; 21 (4): 514-24.

Monoclonal antibodies raised against Xenopus p53 interact with human p73., Le Bras M, Delattre V, Bensaad K, Blandino G, Soussi T., Oncogene. February 14, 2002; 21 (8): 1304-8.

cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA., Hanas JS, Hocker JR, Cheng YG, Lerner MR, Brackett DJ, Lightfoot SA, Hanas RJ, Madhusudhan KT, Moreland RJ., Gene. January 9, 2002; 282 (1-2): 43-52.

Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells., Ohta T, Essner R, Ryu JH, Palazzo RE, Uetake Y, Kuriyama R., J Cell Biol. January 7, 2002; 156 (1): 87-99.                      

QSAR: hydropathic analysis of inhibitors of the p53-mdm2 interaction., Galatin PS, Abraham DJ., Proteins. November 15, 2001; 45 (3): 169-75.

Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells., Kanovsky M, Raffo A, Drew L, Rosal R, Do T, Friedman FK, Rubinstein P, Visser J, Robinson R, Brandt-Rauf PW, Michl J, Fine RL, Pincus MR., Proc Natl Acad Sci U S A. October 23, 2001; 98 (22): 12438-43.

Regulation of the cell cycle by p53 after DNA damage in an amphibian cell line., Bensaad K, Rouillard D, Soussi T., Oncogene. June 28, 2001; 20 (29): 3766-75.

Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein., Liu J, Stevens J, Rote CA, Yost HJ, Hu Y, Neufeld KL, White RL, Matsunami N., Mol Cell. May 1, 2001; 7 (5): 927-36.

Loss of the maintenance methyltransferase, xDnmt1, induces apoptosis in Xenopus embryos., Stancheva I, Hensey C, Meehan RR., EMBO J. April 17, 2001; 20 (8): 1963-73.

Xenopus p63 expression in early ectoderm and neurectoderm., Lu P, Barad M, Vize PD., Mech Dev. April 1, 2001; 102 (1-2): 275-8.              

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage., Anderson L, Henderson C, Adachi Y., Mol Cell Biol. March 1, 2001; 21 (5): 1719-29.

A Xenopus homolog of a human p53-activated gene, PA26, is specifically expressed in the notochord., Hikasa H, Taira M., Mech Dev. February 1, 2001; 100 (2): 309-12.  

Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1., Xia Z, Morales JC, Dunphy WG, Carpenter PB., J Biol Chem. January 26, 2001; 276 (4): 2708-18.

Xrel3 is required for head development in Xenopus laevis., Lake BB, Ford R, Kao KR., Development. January 1, 2001; 128 (2): 263-73.

Critical residues of epitopes recognized by several anti-p53 monoclonal antibodies correspond to key residues of p53 involved in interactions with the mdm2 protein., Portefaix JM, Thebault S, Bourgain-Guglielmetti F, Del Rio M, Granier C, Mani JC, Navarro-Teulon I, Nicolas M, Soussi T, Pau B., J Immunol Methods. October 20, 2000; 244 (1-2): 17-28.

The Mdm2 gene of zebrafish (Danio rerio): preferential expression during development of neural and muscular tissues, and absence of tumor formation after overexpression of its cDNA during early embryogenesis., Thisse C, Neel H, Thisse B, Daujat S, Piette J., Differentiation. October 1, 2000; 66 (2-3): 61-70.

Cell-cycle regulation of the p53-inducible gene B99., Collavin L, Monte M, Verardo R, Pfleger C, Schneider C., FEBS Lett. September 8, 2000; 481 (1): 57-62.

Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage., Costanzo V, Robertson K, Ying CY, Kim E, Avvedimento E, Gottesman M, Grieco D, Gautier J., Mol Cell. September 1, 2000; 6 (3): 649-59.

Form of human p53 protein during nuclear transport in Xenopus laevis embryos., Hara T, Arai K, Koike K., Exp Cell Res. July 10, 2000; 258 (1): 152-61.

A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction., Kim RH, Wang D, Tsang M, Martin J, Huff C, de Caestecker MP, Parks WT, Meng X, Lechleider RJ, Wang T, Roberts AB., Genes Dev. July 1, 2000; 14 (13): 1605-16.            

The amyloid beta peptide abeta (25-35) induces apoptosis independent of p53., Blasko I, Wagner M, Whitaker N, Grubeck-Loebenstein B, Jansen-Dürr P., FEBS Lett. March 24, 2000; 470 (2): 221-5.

T-antigen interactions with chromatin and p53 during the cell cycle in extracts from xenopus eggs., Vassetzky YS, Tchang F, Fanning E, Méchali M., J Cell Biochem. November 1, 1999; 75 (2): 288-99.

Nuclear import of p53 during Xenopus laevis early development in relation to DNA replication and DNA repair., Tchang F, Méchali M., Exp Cell Res. August 25, 1999; 251 (1): 46-56.

Influence of the N-terminal region on the oligomerisation between human and Xenopus laevis p53., Chène P., J Mol Biol. May 21, 1999; 288 (5): 883-90.

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking., Stommel JM, Marchenko ND, Jimenez GS, Moll UM, Hope TJ, Wahl GM., EMBO J. March 15, 1999; 18 (6): 1660-72.

Ras and p53 intracellular targeting with recombinant single-chain Fv (scFv) fragments: a novel approach for cancer therapy?, Cochet O, Gruel N, Fridman WH, Teillaud JL., Cancer Detect Prev. January 1, 1999; 23 (6): 506-10.

Production of a polyclonal antibody raised against recombinant flounder p53 protein., Cachot J, Galgani F, Vincent F., Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. October 1, 1998; 120 (3): 351-6.

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities., Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dötsch V, Andrews NC, Caput D, McKeon F., Mol Cell. September 1, 1998; 2 (3): 305-16.

Overexpression of a novel Xenopus rel mRNA gene induces tumors in early embryos., Yang S, Lockwood A, Hollett P, Ford R, Kao K., J Biol Chem. May 29, 1998; 273 (22): 13746-52.                

Regulation of the specific DNA binding activity of Xenopus laevis p53: evidence for conserved regulation through the carboxy-terminus of the protein., Bessard AC, Garay E, Lacronique V, Legros Y, Demarquay C, Houque A, Portefaix JM, Granier C, Soussi T., Oncogene. February 19, 1998; 16 (7): 883-90.

[A large T-antigen of SV40 virus: involvement in replication of cellular DNA and interactions with nuclear proteins]., Vasetskiĭ ES, Meshali M., Ontogenez. January 1, 1998; 29 (3): 170-7.

A functional analysis of p53 during early development of Xenopus laevis., Amariglio F, Tchang F, Prioleau MN, Soussi T, Cibert C, Méchali M., Oncogene. October 1, 1997; 15 (18): 2191-9.

p53 activity is essential for normal development in Xenopus., Wallingford JB, Seufert DW, Virta VC, Vize PD., Curr Biol. October 1, 1997; 7 (10): 747-57.            

p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases., Saha P, Eichbaum Q, Silberman ED, Mayer BJ, Dutta A., Mol Cell Biol. August 1, 1997; 17 (8): 4338-45.

Cloning of the p53 tumor suppressor gene from the Japanese medaka (Oryzias latipes) and evaluation of mutational hotspots in MNNG-exposed fish., Krause MK, Rhodes LD, Van Beneden RJ., Gene. April 11, 1997; 189 (1): 101-6.

Conservation of structural domains and biochemical activities of the MDM2 protein from Xenopus laevis., Marechal V, Elenbaas B, Taneyhill L, Piette J, Mechali M, Nicolas JC, Levine AJ, Moreau J., Oncogene. March 27, 1997; 14 (12): 1427-33.

B-Myb, a repressed trans-activating protein., Ansieau S, Kowenz-Leutz E, Dechend R, Leutz A., J Mol Med (Berl). January 1, 1997; 75 (11-12): 815-9.

Biochemical properties of Xenopus laevis p53., Hoever M, Herrmann C, Montenarh M., Int J Oncol. January 1, 1997; 10 (1): 195-203.

Tumour suppressor gene p53 in the horse: identification, cloning, sequencing and a possible role in the pathogenesis of equine sarcoid., Bucher K, Szalai G, Marti E, Griot-Wenk ME, Lazary S, Pauli U., Res Vet Sci. September 1, 1996; 61 (2): 114-9.

Cyclin-binding motifs are essential for the function of p21CIP1., Chen J, Saha P, Kornbluth S, Dynlacht BD, Dutta A., Mol Cell Biol. September 1, 1996; 16 (9): 4673-82.

The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a "gain of function" phenotype., Levine AJ, Wu MC, Chang A, Silver A, Attiyeh EF, Lin J, Epstein CB., Ann N Y Acad Sci. September 30, 1995; 768 111-28.

A direct effect of activated human p53 on nuclear DNA replication., Cox LS, Hupp T, Midgley CA, Lane DP., EMBO J. May 1, 1995; 14 (9): 2099-105.

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA., Chen J, Jackson PK, Kirschner MW, Dutta A., Nature. March 23, 1995; 374 (6520): 386-8.

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