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Summary Expression Phenotypes Gene Literature (274) GO Terms (17) Nucleotides (1482) Proteins (65) Interactants (654) Wiki
XB--489467

Papers associated with ran



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The condensin complex is required for proper spindle assembly and chromosome segregation in Xenopus egg extracts., Wignall SM, Deehan R, Maresca TJ, Heald R., J Cell Biol. June 23, 2003; 161 (6): 1041-51.              

Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates., Trotta CR, Lund E, Kahan L, Johnson AW, Dahlberg JE., EMBO J. June 2, 2003; 22 (11): 2841-51.

A role for Ran-GTP and Crm1 in blocking re-replication., Yamaguchi R, Newport J., Cell. April 4, 2003; 113 (1): 115-25.

A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo., Li HY, Wirtz D, Zheng Y., J Cell Biol. March 3, 2003; 160 (5): 635-44.          

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly., Tsai MY, Wiese C, Cao K, Martin O, Donovan P, Ruderman J, Prigent C, Zheng Y., Nat Cell Biol. March 1, 2003; 5 (3): 242-8.

Exportin-5 mediates nuclear export of minihelix-containing RNAs., Gwizdek C, Ossareh-Nazari B, Brownawell AM, Doglio A, Bertrand E, Macara IG, Dargemont C., J Biol Chem. February 21, 2003; 278 (8): 5505-8.

The strategy for coupling the RanGTP gradient to nuclear protein export., Becskei A, Mattaj IW., Proc Natl Acad Sci U S A. February 18, 2003; 100 (4): 1717-22.

N-Glycosylation at two sites critically alters thiazide binding and activity of the rat thiazide-sensitive Na(+):Cl(-) cotransporter., Hoover RS, Poch E, Monroy A, Vázquez N, Nishio T, Gamba G, Hebert SC., J Am Soc Nephrol. February 1, 2003; 14 (2): 271-82.

Nuclear RanGTP is not required for targeting small nucleolar RNAs to the nucleolus., Narayanan A, Eifert J, Marfatia KA, Macara IG, Corbett AH, Terns RM, Terns MP., J Cell Sci. January 1, 2003; 116 (Pt 1): 177-86.

Chromosomal association of Ran during meiotic and mitotic divisions., Hinkle B, Slepchenko B, Rolls MM, Walther TC, Stein PA, Mehlmann LM, Ellenberg J, Terasaki M., J Cell Sci. December 1, 2002; 115 (Pt 23): 4685-93.

Differences in apparent pore sizes of low and high voltage-activated Ca2+ channels., Cataldi M, Perez-Reyes E, Tsien RW., J Biol Chem. November 29, 2002; 277 (48): 45969-76.

Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly., Zhang C, Goldberg MW, Goldberg MW, Moore WJ, Allen TD, Clarke PR., Eur J Cell Biol. November 1, 2002; 81 (11): 623-33.

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells., Gruss OJ, Wittmann M, Yokoyama H, Pepperkok R, Kufer T, Silljé H, Karsenti E, Mattaj IW, Vernos I., Nat Cell Biol. November 1, 2002; 4 (11): 871-9.

Sensitization by extracellular Ca(2+) of rat P2X(5) receptor and its pharmacological properties compared with rat P2X(1)., Wildman SS, Brown SG, Rahman M, Noel CA, Churchill L, Burnstock G, Unwin RJ, King BF., Mol Pharmacol. October 1, 2002; 62 (4): 957-66.

Reconstitution of nuclear protein export in isolated nuclear envelopes., Siebrasse JP, Coutavas E, Peters R., J Cell Biol. September 2, 2002; 158 (5): 849-54.          

Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells., Moore W, Zhang C, Clarke PR., Curr Biol. August 20, 2002; 12 (16): 1442-7.

Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains., Kuersten S, Arts GJ, Walther TC, Englmeier L, Mattaj IW., Mol Cell Biol. August 1, 2002; 22 (16): 5708-20.

Ran binds to chromatin by two distinct mechanisms., Bilbao-Cortés D, Hetzer M, Längst G, Becker PB, Mattaj IW., Curr Biol. July 9, 2002; 12 (13): 1151-6.

The C-terminal extension of the small GTPase Ran is essential for defining the GDP-bound form., Nilsson J, Weis K, Kjems J., J Mol Biol. April 26, 2002; 318 (2): 583-93.

Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts., Kalab P, Weis K, Heald R., Science. March 29, 2002; 295 (5564): 2452-6.

The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo., Bamba C, Bobinnec Y, Fukuda M, Nishida E., Curr Biol. March 19, 2002; 12 (6): 503-7.

Role of importin-beta in the control of nuclear envelope assembly by Ran., Zhang C, Hutchins JR, Mühlhäusser P, Kutay U, Clarke PR., Curr Biol. March 19, 2002; 12 (6): 498-502.

Induction of maturation-promoting factor during Xenopus oocyte maturation uncouples Ca(2+) store depletion from store-operated Ca(2+) entry., Machaca K, Haun S., J Cell Biol. January 7, 2002; 156 (1): 75-85.                

Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly., Hetzer M, Meyer HH, Walther TC, Bilbao-Cortes D, Warren G, Mattaj IW., Nat Cell Biol. December 1, 2001; 3 (12): 1086-91.

Cytosolic import factor- and Ran-independent nuclear transport of ribosomal protein L5., Rudt F, Pieler T., Eur J Cell Biol. November 1, 2001; 80 (11): 661-8.

A light microscope study of the distribution of muscle in the frog esophagus and stomach., Yoshida M., J Smooth Muscle Res. August 1, 2001; 37 (3-4): 95-104.

XMog1, a nuclear ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe mog1p that co-operates with RanBP1 to control generation of Ran-GTP., Nicolás FJ, Moore WJ, Zhang C, Clarke PR., J Cell Sci. August 1, 2001; 114 (Pt 16): 3013-23.

Ran binding protein RanBP1 in zebrafish embryonic development., Mangos S, Vanderbeld B, Krawetz R, Sudol K, Kelly GM., Mol Reprod Dev. July 1, 2001; 59 (3): 235-48.

Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B., Nemergut ME, Mizzen CA, Stukenberg T, Allis CD, Macara IG., Science. May 25, 2001; 292 (5521): 1540-3.

Ran GTPase cycle: oOne mechanism -- two functions., Melchior F., Curr Biol. April 3, 2001; 11 (7): R257-60.

Ran hits the ground running., Walczak CE., Nat Cell Biol. March 1, 2001; 3 (3): E69-70.

Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly., Carazo-Salas RE, Gruss OJ, Mattaj IW, Karsenti E., Nat Cell Biol. March 1, 2001; 3 (3): 228-34.

Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities., Wilde A, Lizarraga SB, Zhang L, Wiese C, Gliksman NR, Walczak CE, Zheng Y., Nat Cell Biol. March 1, 2001; 3 (3): 221-7.

Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system., Zhang C, Clarke PR., Curr Biol. February 6, 2001; 11 (3): 208-12.

Role of importin-beta in coupling Ran to downstream targets in microtubule assembly., Wiese C, Wilde A, Moore MS, Adam SA, Merdes A, Zheng Y., Science. January 26, 2001; 291 (5504): 653-6.

Importin beta is a mitotic target of the small GTPase Ran in spindle assembly., Nachury MV, Maresca TJ, Salmon WC, Waterman-Storer CM, Heald R, Weis K., Cell. January 12, 2001; 104 (1): 95-106.

Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity., Gruss OJ, Carazo-Salas RE, Schatz CA, Guarguaglini G, Kast J, Wilm M, Le Bot N, Vernos I, Karsenti E, Mattaj IW., Cell. January 12, 2001; 104 (1): 83-93.

CRM1- and Ran-independent nuclear export of beta-catenin., Wiechens N, Fagotto F., Curr Biol. January 9, 2001; 11 (1): 18-27.

A Ran-independent pathway for export of spliced mRNA., Clouse KN, Luo MJ, Zhou Z, Reed R., Nat Cell Biol. January 1, 2001; 3 (1): 97-9.

Purification of the vertebrate nuclear pore complex by biochemical criteria., Miller BR, Forbes DJ., Traffic. December 1, 2000; 1 (12): 941-51.

Regulated Ran-binding protein 1 activity is required for organization and function of the mitotic spindle in mammalian cells in vivo., Guarguaglini G, Renzi L, D'Ottavio F, Di Fiore B, Casenghi M, Cundari E, Lavia P., Cell Growth Differ. August 1, 2000; 11 (8): 455-65.

Ran alters nuclear pore complex conformation., Goldberg MW, Goldberg MW, Rutherford SA, Hughes M, Cotter LA, Bagley S, Kiseleva E, Allen TD, Clarke PR., J Mol Biol. July 14, 2000; 300 (3): 519-29.

Structure and expression of Xenopus karyopherin-beta3: definition of a novel synexpression group related to ribosome biogenesis., Wischnewski J, Sölter M, Chen Y, Chen Y, Hollemann T, Pieler T., Mech Dev. July 1, 2000; 95 (1-2): 245-8.                            

RanGTP-binding protein NXT1 facilitates nuclear export of different classes of RNA in vitro., Ossareh-Nazari B, Maison C, Black BE, Lévesque L, Paschal BM, Dargemont C., Mol Cell Biol. July 1, 2000; 20 (13): 4562-71.

Expression of the Xenopus GTP-binding protein gene Ran during embryogenesis., Onuma Y, Nishihara R, Takahashi S, Tanegashima K, Fukui A, Asashima M., Dev Genes Evol. June 1, 2000; 210 (6): 325-7.

Nuclear transport of histone 2b in mammalian cells is signal- and energy-dependent and different from the importin alpha/beta-mediated process., Langer T., Histochem Cell Biol. June 1, 2000; 113 (6): 455-65.

GTP hydrolysis by Ran is required for nuclear envelope assembly., Hetzer M, Bilbao-Cortés D, Walther TC, Gruss OJ, Mattaj IW., Mol Cell. June 1, 2000; 5 (6): 1013-24.

Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts., Zhang C, Clarke PR., Science. May 26, 2000; 288 (5470): 1429-32.

The nuclear import of RCC1 requires a specific nuclear localization sequence receptor, karyopherin alpha3/Qip., Talcott B, Moore MS., J Biol Chem. April 7, 2000; 275 (14): 10099-104.

The targeting of Xcat2 mRNA to the germinal granules depends on a cis-acting germinal granule localization element within the 3'UTR., Kloc M, Bilinski S, Pui-Yee Chan A, Etkin LD., Dev Biol. January 15, 2000; 217 (2): 221-9.          

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