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Summary Expression Phenotypes Gene Literature (274) GO Terms (17) Nucleotides (1482) Proteins (65) Interactants (654) Wiki
XB--489467

Papers associated with ran



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The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo., Bamba C, Bobinnec Y, Fukuda M, Nishida E., Curr Biol. March 19, 2002; 12 (6): 503-7.

Role of importin-beta in the control of nuclear envelope assembly by Ran., Zhang C, Hutchins JR, Mühlhäusser P, Kutay U, Clarke PR., Curr Biol. March 19, 2002; 12 (6): 498-502.

Induction of maturation-promoting factor during Xenopus oocyte maturation uncouples Ca(2+) store depletion from store-operated Ca(2+) entry., Machaca K, Haun S., J Cell Biol. January 7, 2002; 156 (1): 75-85.                

Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly., Hetzer M, Meyer HH, Walther TC, Bilbao-Cortes D, Warren G, Mattaj IW., Nat Cell Biol. December 1, 2001; 3 (12): 1086-91.

Cytosolic import factor- and Ran-independent nuclear transport of ribosomal protein L5., Rudt F, Pieler T., Eur J Cell Biol. November 1, 2001; 80 (11): 661-8.

A light microscope study of the distribution of muscle in the frog esophagus and stomach., Yoshida M., J Smooth Muscle Res. August 1, 2001; 37 (3-4): 95-104.

XMog1, a nuclear ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe mog1p that co-operates with RanBP1 to control generation of Ran-GTP., Nicolás FJ, Moore WJ, Zhang C, Clarke PR., J Cell Sci. August 1, 2001; 114 (Pt 16): 3013-23.

Ran binding protein RanBP1 in zebrafish embryonic development., Mangos S, Vanderbeld B, Krawetz R, Sudol K, Kelly GM., Mol Reprod Dev. July 1, 2001; 59 (3): 235-48.

Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B., Nemergut ME, Mizzen CA, Stukenberg T, Allis CD, Macara IG., Science. May 25, 2001; 292 (5521): 1540-3.

Ran GTPase cycle: oOne mechanism -- two functions., Melchior F., Curr Biol. April 3, 2001; 11 (7): R257-60.

Ran hits the ground running., Walczak CE., Nat Cell Biol. March 1, 2001; 3 (3): E69-70.

Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly., Carazo-Salas RE, Gruss OJ, Mattaj IW, Karsenti E., Nat Cell Biol. March 1, 2001; 3 (3): 228-34.

Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities., Wilde A, Lizarraga SB, Zhang L, Wiese C, Gliksman NR, Walczak CE, Zheng Y., Nat Cell Biol. March 1, 2001; 3 (3): 221-7.

Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system., Zhang C, Clarke PR., Curr Biol. February 6, 2001; 11 (3): 208-12.

Role of importin-beta in coupling Ran to downstream targets in microtubule assembly., Wiese C, Wilde A, Moore MS, Adam SA, Merdes A, Zheng Y., Science. January 26, 2001; 291 (5504): 653-6.

Importin beta is a mitotic target of the small GTPase Ran in spindle assembly., Nachury MV, Maresca TJ, Salmon WC, Waterman-Storer CM, Heald R, Weis K., Cell. January 12, 2001; 104 (1): 95-106.

Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity., Gruss OJ, Carazo-Salas RE, Schatz CA, Guarguaglini G, Kast J, Wilm M, Le Bot N, Vernos I, Karsenti E, Mattaj IW., Cell. January 12, 2001; 104 (1): 83-93.

CRM1- and Ran-independent nuclear export of beta-catenin., Wiechens N, Fagotto F., Curr Biol. January 9, 2001; 11 (1): 18-27.

A Ran-independent pathway for export of spliced mRNA., Clouse KN, Luo MJ, Zhou Z, Reed R., Nat Cell Biol. January 1, 2001; 3 (1): 97-9.

Purification of the vertebrate nuclear pore complex by biochemical criteria., Miller BR, Forbes DJ., Traffic. December 1, 2000; 1 (12): 941-51.

Regulated Ran-binding protein 1 activity is required for organization and function of the mitotic spindle in mammalian cells in vivo., Guarguaglini G, Renzi L, D'Ottavio F, Di Fiore B, Casenghi M, Cundari E, Lavia P., Cell Growth Differ. August 1, 2000; 11 (8): 455-65.

Ran alters nuclear pore complex conformation., Goldberg MW, Goldberg MW, Rutherford SA, Hughes M, Cotter LA, Bagley S, Kiseleva E, Allen TD, Clarke PR., J Mol Biol. July 14, 2000; 300 (3): 519-29.

Structure and expression of Xenopus karyopherin-beta3: definition of a novel synexpression group related to ribosome biogenesis., Wischnewski J, Sölter M, Chen Y, Chen Y, Hollemann T, Pieler T., Mech Dev. July 1, 2000; 95 (1-2): 245-8.                            

RanGTP-binding protein NXT1 facilitates nuclear export of different classes of RNA in vitro., Ossareh-Nazari B, Maison C, Black BE, Lévesque L, Paschal BM, Dargemont C., Mol Cell Biol. July 1, 2000; 20 (13): 4562-71.

Expression of the Xenopus GTP-binding protein gene Ran during embryogenesis., Onuma Y, Nishihara R, Takahashi S, Tanegashima K, Fukui A, Asashima M., Dev Genes Evol. June 1, 2000; 210 (6): 325-7.

Nuclear transport of histone 2b in mammalian cells is signal- and energy-dependent and different from the importin alpha/beta-mediated process., Langer T., Histochem Cell Biol. June 1, 2000; 113 (6): 455-65.

GTP hydrolysis by Ran is required for nuclear envelope assembly., Hetzer M, Bilbao-Cortés D, Walther TC, Gruss OJ, Mattaj IW., Mol Cell. June 1, 2000; 5 (6): 1013-24.

Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts., Zhang C, Clarke PR., Science. May 26, 2000; 288 (5470): 1429-32.

The nuclear import of RCC1 requires a specific nuclear localization sequence receptor, karyopherin alpha3/Qip., Talcott B, Moore MS., J Biol Chem. April 7, 2000; 275 (14): 10099-104.

The targeting of Xcat2 mRNA to the germinal granules depends on a cis-acting germinal granule localization element within the 3'UTR., Kloc M, Bilinski S, Pui-Yee Chan A, Etkin LD., Dev Biol. January 15, 2000; 217 (2): 221-9.          

The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates., Bachi A, Braun IC, Rodrigues JP, Panté N, Ribbeck K, von Kobbe C, Kutay U, Wilm M, Görlich D, Carmo-Fonseca M, Izaurralde E., RNA. January 1, 2000; 6 (1): 136-58.

Rev-mediated nuclear export of RNA is dominant over nuclear retention and is coupled to the Ran-GTPase cycle., Fischer U, Pollard VW, Lührmann R, Teufel M, Michael MW, Dreyfuss G, Malim MH., Nucleic Acids Res. November 1, 1999; 27 (21): 4128-34.

Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer., Adachi M, Fukuda M, Nishida E., EMBO J. October 1, 1999; 18 (19): 5347-58.

Microtubule cytoskeleton: No longer an also Ran., Desai A, Hyman A., Curr Biol. September 23, 1999; 9 (18): R704-7.

Beyond nuclear transport. Ran-GTP as a determinant of spindle assembly., Kahana JA, Cleveland DW., J Cell Biol. September 20, 1999; 146 (6): 1205-10.    

A new role of ran GTPase., Nishimoto T., Biochem Biophys Res Commun. September 7, 1999; 262 (3): 571-4.

Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation., Carazo-Salas RE, Guarguaglini G, Gruss OJ, Segref A, Karsenti E, Mattaj IW., Nature. July 8, 1999; 400 (6740): 178-81.

Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts., Zhang C, Hughes M, Clarke PR., J Cell Sci. July 1, 1999; 112 ( Pt 14) 2453-61.

Efficiency of importin alpha/beta-mediated nuclear localization sequence recognition and nuclear import. Differential role of NTF2., Hu W, Jans DA., J Biol Chem. May 28, 1999; 274 (22): 15820-7.

Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran., Wilde A, Zheng Y., Science. May 21, 1999; 284 (5418): 1359-62.

Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran., Ohba T, Nakamura M, Nishitani H, Nishimoto T., Science. May 21, 1999; 284 (5418): 1356-8.

The ran GTPase regulates mitotic spindle assembly., Kalab P, Pu RT, Dasso M., Curr Biol. May 6, 1999; 9 (9): 481-4.

The importin beta/importin 7 heterodimer is a functional nuclear import receptor for histone H1., Jäkel S, Albig W, Kutay U, Bischoff FR, Schwamborn K, Doenecke D, Görlich D., EMBO J. May 4, 1999; 18 (9): 2411-23.

CRM1-mediated recycling of snurportin 1 to the cytoplasm., Paraskeva E, Izaurralde E, Bischoff FR, Huber J, Kutay U, Hartmann E, Lührmann R, Görlich D., J Cell Biol. April 19, 1999; 145 (2): 255-64.              

The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2)., Stewart M, Kent HM, McCoy AJ., J Mol Biol. December 18, 1998; 284 (5): 1517-27.

The role of exportin-t in selective nuclear export of mature tRNAs., Arts GJ, Kuersten S, Romby P, Ehresmann B, Mattaj IW., EMBO J. December 15, 1998; 17 (24): 7430-41.

Proofreading and aminoacylation of tRNAs before export from the nucleus., Lund E, Dahlberg JE., Science. December 11, 1998; 282 (5396): 2082-5.

Separate nuclear import pathways converge on the nucleoporin Nup153 and can be dissected with dominant-negative inhibitors., Shah S, Forbes DJ., Curr Biol. December 1, 1998; 8 (25): 1376-86.

The role of the ran GTPase in nuclear assembly and DNA replication: characterisation of the effects of Ran mutants., Hughes M, Zhang C, Avis JM, Hutchison CJ, Clarke PR., J Cell Sci. October 1, 1998; 111 ( Pt 20) 3017-26.

Xgrip109: a gamma tubulin-associated protein with an essential role in gamma tubulin ring complex (gammaTuRC) assembly and centrosome function., Martin OC, Gunawardane RN, Iwamatsu A, Zheng Y., J Cell Biol. May 4, 1998; 141 (3): 675-87.                

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