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Summary Expression Phenotypes Gene Literature (274) GO Terms (17) Nucleotides (1482) Proteins (65) Interactants (654) Wiki
XB--489467

Papers associated with ran



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Regulated Ran-binding protein 1 activity is required for organization and function of the mitotic spindle in mammalian cells in vivo., Guarguaglini G, Renzi L, D'Ottavio F, Di Fiore B, Casenghi M, Cundari E, Lavia P., Cell Growth Differ. August 1, 2000; 11 (8): 455-65.

Ran alters nuclear pore complex conformation., Goldberg MW, Goldberg MW, Rutherford SA, Hughes M, Cotter LA, Bagley S, Kiseleva E, Allen TD, Clarke PR., J Mol Biol. July 14, 2000; 300 (3): 519-29.

Structure and expression of Xenopus karyopherin-beta3: definition of a novel synexpression group related to ribosome biogenesis., Wischnewski J, Sölter M, Chen Y, Chen Y, Hollemann T, Pieler T., Mech Dev. July 1, 2000; 95 (1-2): 245-8.                            

RanGTP-binding protein NXT1 facilitates nuclear export of different classes of RNA in vitro., Ossareh-Nazari B, Maison C, Black BE, Lévesque L, Paschal BM, Dargemont C., Mol Cell Biol. July 1, 2000; 20 (13): 4562-71.

Expression of the Xenopus GTP-binding protein gene Ran during embryogenesis., Onuma Y, Nishihara R, Takahashi S, Tanegashima K, Fukui A, Asashima M., Dev Genes Evol. June 1, 2000; 210 (6): 325-7.

Nuclear transport of histone 2b in mammalian cells is signal- and energy-dependent and different from the importin alpha/beta-mediated process., Langer T., Histochem Cell Biol. June 1, 2000; 113 (6): 455-65.

GTP hydrolysis by Ran is required for nuclear envelope assembly., Hetzer M, Bilbao-Cortés D, Walther TC, Gruss OJ, Mattaj IW., Mol Cell. June 1, 2000; 5 (6): 1013-24.

Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts., Zhang C, Clarke PR., Science. May 26, 2000; 288 (5470): 1429-32.

The nuclear import of RCC1 requires a specific nuclear localization sequence receptor, karyopherin alpha3/Qip., Talcott B, Moore MS., J Biol Chem. April 7, 2000; 275 (14): 10099-104.

The targeting of Xcat2 mRNA to the germinal granules depends on a cis-acting germinal granule localization element within the 3'UTR., Kloc M, Bilinski S, Pui-Yee Chan A, Etkin LD., Dev Biol. January 15, 2000; 217 (2): 221-9.          

The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates., Bachi A, Braun IC, Rodrigues JP, Panté N, Ribbeck K, von Kobbe C, Kutay U, Wilm M, Görlich D, Carmo-Fonseca M, Izaurralde E., RNA. January 1, 2000; 6 (1): 136-58.

Rev-mediated nuclear export of RNA is dominant over nuclear retention and is coupled to the Ran-GTPase cycle., Fischer U, Pollard VW, Lührmann R, Teufel M, Michael MW, Dreyfuss G, Malim MH., Nucleic Acids Res. November 1, 1999; 27 (21): 4128-34.

Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer., Adachi M, Fukuda M, Nishida E., EMBO J. October 1, 1999; 18 (19): 5347-58.

Microtubule cytoskeleton: No longer an also Ran., Desai A, Hyman A., Curr Biol. September 23, 1999; 9 (18): R704-7.

Beyond nuclear transport. Ran-GTP as a determinant of spindle assembly., Kahana JA, Cleveland DW., J Cell Biol. September 20, 1999; 146 (6): 1205-10.    

A new role of ran GTPase., Nishimoto T., Biochem Biophys Res Commun. September 7, 1999; 262 (3): 571-4.

Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation., Carazo-Salas RE, Guarguaglini G, Gruss OJ, Segref A, Karsenti E, Mattaj IW., Nature. July 8, 1999; 400 (6740): 178-81.

Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts., Zhang C, Hughes M, Clarke PR., J Cell Sci. July 1, 1999; 112 ( Pt 14) 2453-61.

Efficiency of importin alpha/beta-mediated nuclear localization sequence recognition and nuclear import. Differential role of NTF2., Hu W, Jans DA., J Biol Chem. May 28, 1999; 274 (22): 15820-7.

Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran., Wilde A, Zheng Y., Science. May 21, 1999; 284 (5418): 1359-62.

Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran., Ohba T, Nakamura M, Nishitani H, Nishimoto T., Science. May 21, 1999; 284 (5418): 1356-8.

The ran GTPase regulates mitotic spindle assembly., Kalab P, Pu RT, Dasso M., Curr Biol. May 6, 1999; 9 (9): 481-4.

The importin beta/importin 7 heterodimer is a functional nuclear import receptor for histone H1., Jäkel S, Albig W, Kutay U, Bischoff FR, Schwamborn K, Doenecke D, Görlich D., EMBO J. May 4, 1999; 18 (9): 2411-23.

CRM1-mediated recycling of snurportin 1 to the cytoplasm., Paraskeva E, Izaurralde E, Bischoff FR, Huber J, Kutay U, Hartmann E, Lührmann R, Görlich D., J Cell Biol. April 19, 1999; 145 (2): 255-64.              

The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2)., Stewart M, Kent HM, McCoy AJ., J Mol Biol. December 18, 1998; 284 (5): 1517-27.

The role of exportin-t in selective nuclear export of mature tRNAs., Arts GJ, Kuersten S, Romby P, Ehresmann B, Mattaj IW., EMBO J. December 15, 1998; 17 (24): 7430-41.

Proofreading and aminoacylation of tRNAs before export from the nucleus., Lund E, Dahlberg JE., Science. December 11, 1998; 282 (5396): 2082-5.

Separate nuclear import pathways converge on the nucleoporin Nup153 and can be dissected with dominant-negative inhibitors., Shah S, Forbes DJ., Curr Biol. December 1, 1998; 8 (25): 1376-86.

The role of the ran GTPase in nuclear assembly and DNA replication: characterisation of the effects of Ran mutants., Hughes M, Zhang C, Avis JM, Hutchison CJ, Clarke PR., J Cell Sci. October 1, 1998; 111 ( Pt 20) 3017-26.

Xgrip109: a gamma tubulin-associated protein with an essential role in gamma tubulin ring complex (gammaTuRC) assembly and centrosome function., Martin OC, Gunawardane RN, Iwamatsu A, Zheng Y., J Cell Biol. May 4, 1998; 141 (3): 675-87.                

Modification of Ran GTPase-activating protein by the small ubiquitin-related modifier SUMO-1 requires Ubc9, an E2-type ubiquitin-conjugating enzyme homologue., Lee GW, Melchior F, Matunis MJ, Mahajan R, Tian Q, Anderson P., J Biol Chem. March 13, 1998; 273 (11): 6503-7.

Identification of a nuclear export receptor for tRNA., Arts GJ, Fornerod M, Mattaj IW., Curr Biol. March 12, 1998; 8 (6): 305-14.

Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin., Fagotto F, Glück U, Gumbiner BM., Curr Biol. February 12, 1998; 8 (4): 181-90.

Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2., Saitoh H, Sparrow DB, Shiomi T, Pu RT, Nishimoto T, Mohun TJ, Dasso M., Curr Biol. January 15, 1998; 8 (2): 121-4.

Inhibition of mRNA export in vertebrate cells by nuclear export signal conjugates., Pasquinelli AE, Powers MA, Lund E, Forbes D, Dahlberg JE., Proc Natl Acad Sci U S A. December 23, 1997; 94 (26): 14394-9.

Xenopus Ran-binding protein 1: molecular interactions and effects on nuclear assembly in Xenopus egg extracts., Nicolás FJ, Zhang C, Hughes M, Goldberg MW, Watton SJ, Clarke PR., J Cell Sci. December 1, 1997; 110 ( Pt 24) 3019-30.

The balance of RanBP1 and RCC1 is critical for nuclear assembly and nuclear transport., Pu RT, Dasso M., Mol Biol Cell. October 1, 1997; 8 (10): 1955-70.

Selection and nuclear immobilization of exportable RNAs., Grimm C, Lund E, Dahlberg JE., Proc Natl Acad Sci U S A. September 16, 1997; 94 (19): 10122-7.

The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export., Saavedra C, Felber B, Izaurralde E., Curr Biol. September 1, 1997; 7 (9): 619-28.

A novel class of RanGTP binding proteins., Görlich D, Dabrowski M, Bischoff FR, Kutay U, Bork P, Hartmann E, Prehn S, Izaurralde E., J Cell Biol. July 14, 1997; 138 (1): 65-80.                    

Inhibition of Ran guanosine triphosphatase-dependent nuclear transport by the matrix protein of vesicular stomatitis virus., Her LS, Lund E, Dahlberg JE., Science. June 20, 1997; 276 (5320): 1845-8.

RanBP2 associates with Ubc9p and a modified form of RanGAP1., Saitoh H, Pu R, Cavenagh M, Dasso M., Proc Natl Acad Sci U S A. April 15, 1997; 94 (8): 3736-41.

Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex., Kutay U, Izaurralde E, Bischoff FR, Mattaj IW, Görlich D., EMBO J. March 17, 1997; 16 (6): 1153-63.

Molecular mechanisms of nuclear protein transport., Moroianu J., Crit Rev Eukaryot Gene Expr. January 1, 1997; 7 (1-2): 61-72.

Properties of cloned ATP-sensitive K+ currents expressed in Xenopus oocytes., Gribble FM, Ashfield R, Ammälä C, Ashcroft FM., J Physiol. January 1, 1997; 498 ( Pt 1) 87-98.

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex., Matunis MJ, Coutavas E, Blobel G., J Cell Biol. December 1, 1996; 135 (6 Pt 1): 1457-70.

Identification of different roles for RanGDP and RanGTP in nuclear protein import., Görlich D, Panté N, Kutay U, Aebi U, Bischoff FR., EMBO J. October 15, 1996; 15 (20): 5584-94.

Direct and indirect association of the small GTPase ran with nuclear pore proteins and soluble transport factors: studies in Xenopus laevis egg extracts., Saitoh H, Cooke CA, Burgess WH, Earnshaw WC, Dasso M., Mol Biol Cell. September 1, 1996; 7 (9): 1319-34.

Protein import into the nucleus., Schlenstedt G., FEBS Lett. June 24, 1996; 389 (1): 75-9.

RAN/TC4 mutants identify a common requirement for snRNP and protein import into the nucleus., Palacios I, Weis K, Klebe C, Mattaj IW, Dingwall C., J Cell Biol. May 1, 1996; 133 (3): 485-94.

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