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Summary Expression Phenotypes Gene Literature (250) GO Terms (9) Nucleotides (319) Proteins (48) Interactants (1056) Wiki
XB--1018192

Papers associated with smad1



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Calmodulin differentially modulates Smad1 and Smad2 signaling., Scherer A, Graff JM., J Biol Chem. December 29, 2000; 275 (52): 41430-8.

Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells., Wang W, Mariani FV, Harland RM, Luo K., Proc Natl Acad Sci U S A. December 19, 2000; 97 (26): 14394-9.          

The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning., Kazanskaya O, Glinka A, Niehrs C., Development. November 1, 2000; 127 (22): 4981-92.              

The bone morphogenetic protein 2 signaling mediator Smad1 participates predominantly in osteogenic and not in chondrogenic differentiation in mesenchymal progenitors C3H10T1/2., Ju W, Hoffmann A, Verschueren K, Tylzanowski P, Kaps C, Gross G, Huylebroeck D., J Bone Miner Res. October 1, 2000; 15 (10): 1889-99.

Structural basis for the functional difference between Smad2 and Smad3 in FAST-2 (forkhead activin signal transducer-2)-mediated transcription., Nagarajan RP, Chen Y., Biochem J. August 15, 2000; 350 Pt 1 253-9.

BMP signaling is required for heart formation in vertebrates., Shi Y, Shi Y, Katsev S, Cai C, Evans S., Dev Biol. August 15, 2000; 224 (2): 226-37.          

Smad1 and Smad4 are components of the bone morphogenetic protein-4 (BMP-4)-induced transcription complex of the Xvent-2B promoter., Henningfeld KA, Rastegar S, Adler G, Knöchel W., J Biol Chem. July 21, 2000; 275 (29): 21827-35.

A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction., Kim RH, Wang D, Tsang M, Martin J, Huff C, de Caestecker MP, Parks WT, Meng X, Lechleider RJ, Wang T, Roberts AB., Genes Dev. July 1, 2000; 14 (13): 1605-16.            

Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development., Faure S, Lee MA, Keller T, ten Dijke P, Whitman M., Development. July 1, 2000; 127 (13): 2917-31.      

Phenotypic effects in Xenopus and zebrafish suggest that one-eyed pinhead functions as antagonist of BMP signalling., Kiecker C, Müller F, Wu W, Glinka A, Strähle U, Niehrs C., Mech Dev. June 1, 2000; 94 (1-2): 37-46.          

Mouse smad8 phosphorylation downstream of BMP receptors ALK-2, ALK-3, and ALK-6 induces its association with Smad4 and transcriptional activity., Kawai S, Faucheu C, Gallea S, Spinella-Jaegle S, Atfi A, Baron R, Roman SR., Biochem Biophys Res Commun. May 19, 2000; 271 (3): 682-7.

FOG acts as a repressor of red blood cell development in Xenopus., Deconinck AE, Mead PE, Tevosian SG, Crispino JD, Katz SG, Zon LI, Orkin SH., Development. May 1, 2000; 127 (10): 2031-40.              

OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways., Hata A, Seoane J, Lagna G, Montalvo E, Hemmati-Brivanlou A, Massagué J., Cell. January 21, 2000; 100 (2): 229-40.      

Activation of Stat3 by cytokine receptor gp130 ventralizes Xenopus embryos independent of BMP-4., Nishinakamura R, Matsumoto Y, Matsuda T, Ariizumi T, Heike T, Asashima M, Yokota T., Dev Biol. December 15, 1999; 216 (2): 481-90.              

Cardiac looping and the vertebrate left-right axis: antagonism of left-sided Vg1 activity by a right-sided ALK2-dependent BMP pathway., Ramsdell AF, Yost HJ., Development. December 1, 1999; 126 (23): 5195-205.        

Characterization of zebrafish smad1, smad2 and smad5: the amino-terminus of smad1 and smad5 is required for specific function in the embryo., Müller F, Blader P, Rastegar S, Fischer N, Knöchel W, Strähle U., Mech Dev. October 1, 1999; 88 (1): 73-88.  

A role for the homeobox gene Xvex-1 as part of the BMP-4 ventral signaling pathway., Shapira E, Marom K, Yelin R, Levy A, Fainsod A., Mech Dev. August 1, 1999; 86 (1-2): 99-111.            

SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes., Verschueren K, Remacle JE, Collart C, Kraft H, Baker BS, Tylzanowski P, Nelles L, Wuytens G, Su MT, Bodmer R, Smith JC, Huylebroeck D., J Biol Chem. July 16, 1999; 274 (29): 20489-98.                

Functional analysis of human Smad1: role of the amino-terminal domain., Xu RH, Lechleider RJ, Shih HM, Hao CF, Sredni D, Roberts AB, Kung H., Biochem Biophys Res Commun. May 10, 1999; 258 (2): 366-73.      

Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals., Christian JL, Nakayama T., Bioessays. May 1, 1999; 21 (5): 382-90.

Identification of two Smad4 proteins in Xenopus. Their common and distinct properties., Masuyama N, Hanafusa H, Kusakabe M, Shibuya H, Nishida E., J Biol Chem. April 23, 1999; 274 (17): 12163-70.                

A molecular basis for Smad specificity., Lagna G, Hemmati-Brivanlou A., Dev Dyn. March 1, 1999; 214 (3): 269-77.

The embryonic expression of the tissue-specific transcription factor HNF1alpha in Xenopus: rapid activation by HNF4 and delayed induction by mesoderm inducers., Nastos A, Pogge von Strandmann E, Weber H, Ryffel GU., Nucleic Acids Res. December 15, 1998; 26 (24): 5602-8.

Mitogen-activated protein kinase and neural specification in Xenopus., Uzgare AR, Uzman JA, El-Hodiri HM, Sater AK., Proc Natl Acad Sci U S A. December 8, 1998; 95 (25): 14833-8.

A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis., Weisberg E, Winnier GE, Chen X, Farnsworth CL, Hogan BL, Whitman M., Mech Dev. December 1, 1998; 79 (1-2): 17-27.        

Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores., Chen RH, Shevchenko A, Mann M, Murray AW., J Cell Biol. October 19, 1998; 143 (2): 283-95.                    

Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2., Macías-Silva M, Hoodless PA, Tang SJ, Buchwald M, Wrana JL., J Biol Chem. October 2, 1998; 273 (40): 25628-36.

Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptors., Souchelnytskyi S, Nakayama T, Nakao A, Morén A, Heldin CH, Christian JL, ten Dijke P., J Biol Chem. September 25, 1998; 273 (39): 25364-70.        

Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins., Mead PE, Zhou Y, Lustig KD, Huber TL, Kirschner MW, Zon LI., Proc Natl Acad Sci U S A. September 15, 1998; 95 (19): 11251-6.              

Smad7 inhibits mesoderm formation and promotes neural cell fate in Xenopus embryos., Bhushan A, Chen Y, Vale W., Dev Biol. August 15, 1998; 200 (2): 260-8.              

Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes., Nguyen VH, Schmid B, Trout J, Connors SA, Ekker M, Mullins MC., Dev Biol. July 1, 1998; 199 (1): 93-110.

Smad6 functions as an intracellular antagonist of some TGF-beta family members during Xenopus embryogenesis., Nakayama T, Gardner H, Berg LK, Christian JL., Genes Cells. June 1, 1998; 3 (6): 387-94.                

Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer., Casellas R, Brivanlou AH., Dev Biol. June 1, 1998; 198 (1): 1-12.                

Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression., Crease DJ, Dyson S, Gurdon JB., Proc Natl Acad Sci U S A. April 14, 1998; 95 (8): 4398-403.

Xenopus Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning., Nakayama T, Snyder MA, Grewal SS, Tsuneizumi K, Tabata T, Christian JL., Development. March 1, 1998; 125 (5): 857-67.                  

Role of TAK1 and TAB1 in BMP signaling in early Xenopus development., Shibuya H, Iwata H, Masuyama N, Gotoh Y, Yamaguchi K, Irie K, Matsumoto K, Nishida E, Ueno N., EMBO J. February 16, 1998; 17 (4): 1019-28.

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor., Hata A, Lagna G, Massagué J, Hemmati-Brivanlou A., Genes Dev. January 15, 1998; 12 (2): 186-97.          

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes., Liu F, Pouponnot C, Massagué J., Genes Dev. December 1, 1997; 11 (23): 3157-67.

The homeobox gene PV.1 mediates specification of the prospective neural ectoderm in Xenopus embryos., Ault KT, Xu RH, Kung HF, Jamrich M., Dev Biol. December 1, 1997; 192 (1): 162-71.            

Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads., Candia AF, Watabe T, Hawley SH, Onichtchouk D, Zhang Y, Derynck R, Niehrs C, Cho KW., Development. November 1, 1997; 124 (22): 4467-80.

Xenopus FK 506-binding protein homolog induces a secondary axis in frog embryos, which is inhibited by coexisting BMP 4 signaling., Nishinakamura R, Matsumoto Y, Uochi T, Asashima M, Yokota T., Biochem Biophys Res Commun. October 20, 1997; 239 (2): 585-91.            

Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1., Wilson PA, Lagna G, Suzuki A, Hemmati-Brivanlou A., Development. August 1, 1997; 124 (16): 3177-84.

Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus., Dosch R, Gawantka V, Delius H, Blumenstock C, Niehrs C., Development. June 1, 1997; 124 (12): 2325-34.          

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function., Zhang Y, Musci T, Derynck R., Curr Biol. April 1, 1997; 7 (4): 270-6.

Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway., Nakao A, Röijer E, Imamura T, Souchelnytskyi S, Stenman G, Heldin CH, ten Dijke P., J Biol Chem. January 31, 1997; 272 (5): 2896-900.

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways., Lagna G, Hata A, Hemmati-Brivanlou A, Massagué J., Nature. October 31, 1996; 383 (6603): 832-6.

Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor., Thomsen GH., Development. August 1, 1996; 122 (8): 2359-66.              

A human Mad protein acting as a BMP-regulated transcriptional activator., Liu F, Hata A, Baker JC, Doody J, Cárcamo J, Harland RM, Massagué J., Nature. June 13, 1996; 381 (6583): 620-3.

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily., Graff JM, Bansal A, Melton DA., Cell. May 17, 1996; 85 (4): 479-87.

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