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Summary Expression Phenotypes Gene Literature (106) GO Terms (4) Nucleotides (57) Proteins (33) Interactants (107) Wiki
XB--1010661

Papers associated with kcna1



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Jingzhaotoxin-IX, a novel gating modifier of both sodium and potassium channels from Chinese tarantula Chilobrachys jingzhao., Deng M, Kuang F, Sun Z, Tao H, Cai T, Zhong L, Chen Z, Xiao Y, Liang S., Neuropharmacology. August 1, 2009; 57 (2): 77-87.

Syntaxin modulates Kv1.1 through dual action on channel surface expression and conductance., Feinshreiber L, Chikvashvili D, Michaelevski I, Lotan I., Biochemistry. May 19, 2009; 48 (19): 4109-14.

Contribution of the central hydrophobic residue in the PXP motif of voltage-dependent K+ channels to S6 flexibility and gating properties., Imbrici P, Grottesi A, D'Adamo MC, Mannucci R, Tucker SJ, Pessia M., Channels (Austin). January 1, 2009; 3 (1): 39-45.

A novel KCNA1 mutation identified in an Italian family affected by episodic ataxia type 1., Imbrici P, Gualandi F, D'Adamo MC, Masieri MT, Cudia P, De Grandis D, Mannucci R, Nicoletti I, Tucker SJ, Ferlini A, Pessia M., Neuroscience. December 2, 2008; 157 (3): 577-87.

A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes., Abbas N, Belghazi M, Abdel-Mottaleb Y, Tytgat J, Bougis PE, Martin-Eauclaire MF., Biochem Biophys Res Commun. November 21, 2008; 376 (3): 525-30.

Hemitoxin, the first potassium channel toxin from the venom of the Iranian scorpion Hemiscorpius lepturus., Srairi-Abid N, Shahbazzadeh D, Chatti I, Mlayah-Bellalouna S, Mejdoub H, Borchani L, Benkhalifa R, Akbari A, El Ayeb M., FEBS J. September 1, 2008; 275 (18): 4641-50.

OdK2, a Kv1.3 channel-selective toxin from the venom of the Iranian scorpion Odonthobuthus doriae., Abdel-Mottaleb Y, Vandendriessche T, Clynen E, Landuyt B, Jalali A, Vatanpour H, Schoofs L, Tytgat J., Toxicon. June 15, 2008; 51 (8): 1424-30.

Functional coupling between the Kv1.1 channel and aldoketoreductase Kvbeta1., Pan Y, Weng J, Cao Y, Bhosle RC, Zhou M., J Biol Chem. March 28, 2008; 283 (13): 8634-42.

Peripheral nerve hyperexcitability due to dominant-negative KCNQ2 mutations., Wuttke TV, Jurkat-Rott K, Paulus W, Garncarek M, Lehmann-Horn F, Lerche H., Neurology. November 27, 2007; 69 (22): 2045-53.

Interaction of syntaxin with a single Kv1.1 channel: a possible mechanism for modulating neuronal excitability., Michaelevski I, Korngreen A, Lotan I., Pflugers Arch. June 1, 2007; 454 (3): 477-94.

Functional analysis of a novel potassium channel (KCNA1) mutation in hereditary myokymia., Chen H, von Hehn C, Kaczmarek LK, Ment LR, Pober BR, Hisama FM., Neurogenetics. April 1, 2007; 8 (2): 131-5.      

Episodic ataxia type 1 mutation F184C alters Zn2+-induced modulation of the human K+ channel Kv1.4-Kv1.1/Kvbeta1.1., Imbrici P, D'Adamo MC, Cusimano A, Pessia M., Am J Physiol Cell Physiol. February 1, 2007; 292 (2): C778-87.

Episodic ataxia type 1 mutations in the KCNA1 gene impair the fast inactivation properties of the human potassium channels Kv1.4-1.1/Kvbeta1.1 and Kv1.4-1.1/Kvbeta1.2., Imbrici P, D'Adamo MC, Kullmann DM, Pessia M., Eur J Neurosci. December 1, 2006; 24 (11): 3073-83.

A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction., Persson AS, Klement G, Almgren M, Sahlholm K, Nilsson J, Petersson S, Arhem P, Schalling M, Lavebratt C., BMC Neurosci. November 23, 2005; 6 65.          

Stichodactyla helianthus peptide, a pharmacological tool for studying Kv3.2 channels., Yan L, Herrington J, Goldberg E, Dulski PM, Bugianesi RM, Slaughter RS, Banerjee P, Brochu RM, Priest BT, Kaczorowski GJ, Rudy B, Garcia ML., Mol Pharmacol. May 1, 2005; 67 (5): 1513-21.

Functional coupling of intracellular calcium and inactivation of voltage-gated Kv1.1/Kvbeta1.1 A-type K+ channels., Jow F, Zhang ZH, Kopsco DC, Carroll KC, Wang K., Proc Natl Acad Sci U S A. October 26, 2004; 101 (43): 15535-40.

An episodic ataxia type-1 mutation in the S1 segment sensitises the hKv1.1 potassium channel to extracellular Zn2+., Cusimano A, Cristina D'Adamo M, Pessia M., FEBS Lett. October 8, 2004; 576 (1-2): 237-44.

Molecular cloning and expression of a Kv1.1-like potassium channel from the electric organ of Electrophorus electricus., Thornhill WB, Watanabe I, Sutachan JJ, Wu MB, Wu X, Zhu J, Recio-Pinto E., J Membr Biol. November 1, 2003; 196 (1): 1-8.

KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels., Grunnet M, Rasmussen HB, Hay-Schmidt A, Rosenstierne M, Klaerke DA, Olesen SP, Jespersen T., Biophys J. September 1, 2003; 85 (3): 1525-37.

Synthesis and characterization of Pi4, a scorpion toxin from Pandinus imperator that acts on K+ channels., M'Barek S, Mosbah A, Sandoz G, Fajloun Z, Olamendi-Portugal T, Rochat H, Sampieri F, Guijarro JI, Mansuelle P, Delepierre M, De Waard M, Sabatier JM., Eur J Biochem. September 1, 2003; 270 (17): 3583-92.

Local anesthetic block of Kv channels: role of the S6 helix and the S5-S6 linker for bupivacaine action., Nilsson J, Madeja M, Arhem P., Mol Pharmacol. June 1, 2003; 63 (6): 1417-29.

Early embryonic expression of ion channels and pumps in chick and Xenopus development., Rutenberg J, Cheng SM, Levin M., Dev Dyn. December 1, 2002; 225 (4): 469-84.                            

Modulation of a brain voltage-gated K+ channel by syntaxin 1A requires the physical interaction of Gbetagamma with the channel., Michaelevski I, Chikvashvili D, Tsuk S, Fili O, Lohse MJ, Singer-Lahat D, Lotan I., J Biol Chem. September 20, 2002; 277 (38): 34909-17.

Episodic ataxia type 1 mutations in the human Kv1.1 potassium channel alter hKvbeta 1-induced N-type inactivation., Maylie B, Bissonnette E, Virk M, Adelman JP, Maylie JG., J Neurosci. June 15, 2002; 22 (12): 4786-93.

Characteristics of brain Kv1 channels tailored to mimic native counterparts by tandem linkage of alpha subunits: implications for K+ channelopathies., Akhtar S, Shamotienko O, Papakosta M, Ali F, Dolly JO., J Biol Chem. May 10, 2002; 277 (19): 16376-82.

Genetic analysis of the mammalian K+ channel beta subunit Kvbeta 2 (Kcnab2)., McCormack K, Connor JX, Zhou L, Ho LL, Ganetzky B, Chiu SY, Messing A., J Biol Chem. April 12, 2002; 277 (15): 13219-28.

Variable K(+) channel subunit dysfunction in inherited mutations of KCNA1., Rea R, Spauschus A, Eunson LH, Hanna MG, Kullmann DM., J Physiol. January 1, 2002; 538 (Pt 1): 5-23.

Functional and molecular expression of a voltage-dependent K(+) channel (Kv1.1) in interstitial cells of Cajal., Hatton WJ, Mason HS, Carl A, Doherty P, Latten MJ, Kenyon JL, Sanders KM, Horowitz B., J Physiol. June 1, 2001; 533 (Pt 2): 315-27.

Gallamine triethiodide selectively blocks voltage-gated potassium channels in Ranvier nodes., Hinck D, Wulff H, Koppenhöfer E., Gen Physiol Biophys. March 1, 2001; 20 (1): 83-95.

Expression cloning of KCRF, a potassium channel regulatory factor., Keren-Raifman T, Ivanina T, Bismuth Y, Dascal N., Biochem Biophys Res Commun. August 11, 2000; 274 (3): 852-8.

Chemical synthesis and characterization of Pi1, a scorpion toxin from Pandinus imperator active on K+ channels., Fajloun Z, Carlier E, Lecomte C, Geib S, Di Luccio E, Bichet D, Mabrouk K, Rochat H, De Waard M, Sabatier JM., Eur J Biochem. August 1, 2000; 267 (16): 5149-55.

Maurotoxin and the Kv1.1 channel: voltage-dependent binding upon enantiomerization of the scorpion toxin disulfide bridge Cys31-Cys34., Lecomte C, Ben Khalifa R, Martin-Eauclaire MF, Kharrat R, El Ayeb M, Darbon H, Rochat H, Crest M, Sabatier JM., J Pept Res. March 1, 2000; 55 (3): 246-54.

A functional spliced-variant of beta 2 subunit of Kv1 channels in C6 glioma cells and reactive astrocytes from rat lesioned cerebellum., Akhtar S, McIntosh P, Bryan-Sisneros A, Barratt L, Robertson B, Dolly JO., Biochemistry. December 21, 1999; 38 (51): 16984-92.

Mapping the functional anatomy of BgK on Kv1.1, Kv1.2, and Kv1.3. Clues to design analogs with enhanced selectivity., Alessandri-Haber N, Lecoq A, Gasparini S, Grangier-Macmath G, Jacquet G, Harvey AL, de Medeiros C, Rowan EG, Gola M, Ménez A, Crest M., J Biol Chem. December 10, 1999; 274 (50): 35653-61.

NMR structure and functional characteristics of the hydrophilic N terminus of the potassium channel beta-subunit Kvbeta1.1., Wissmann R, Baukrowitz T, Kalbacher H, Kalbitzer HR, Ruppersberg JP, Pongs O, Antz C, Fakler B., J Biol Chem. December 10, 1999; 274 (50): 35521-5.

Modal behavior of the Kv1.1 channel conferred by the Kvbeta1.1 subunit and its regulation by dephosphorylation of Kv1.1., Singer-Lahat D, Dascal N, Lotan I., Pflugers Arch. December 1, 1999; 439 (1-2): 18-26.

Inhibition of neuronal KV potassium currents by the antidepressant drug, fluoxetine., Yeung SY, Millar JA, Mathie A., Br J Pharmacol. December 1, 1999; 128 (7): 1609-15.

Distribution in rat brain of binding sites of kaliotoxin, a blocker of Kv1.1 and Kv1.3 alpha-subunits., Mourre C, Chernova MN, Martin-Eauclaire MF, Bessone R, Jacquet G, Gola M, Alper SL, Crest M., J Pharmacol Exp Ther. December 1, 1999; 291 (3): 943-52.

Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin., Pennington MW, Lanigan MD, Kalman K, Mahnir VM, Rauer H, McVaugh CT, Behm D, Donaldson D, Chandy KG, Kem WR, Norton RS., Biochemistry. November 2, 1999; 38 (44): 14549-58.

Voltage sensitivity and gating charge in Shaker and Shab family potassium channels., Islas LD, Sigworth FJ., J Gen Physiol. November 1, 1999; 114 (5): 723-42.                      

Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K(+) channel function., D'Adamo MC, Imbrici P, Sponcichetti F, Pessia M., FASEB J. August 1, 1999; 13 (11): 1335-45.

Identification of residues in dendrotoxin K responsible for its discrimination between neuronal K+ channels containing Kv1.1 and 1.2 alpha subunits., Wang FC, Bell N, Reid P, Smith LA, McIntosh P, Robertson B, Dolly JO., Eur J Biochem. July 1, 1999; 263 (1): 222-9.

Protein kinase C inhibits Kv1.1 potassium channel function., Boland LM, Jackson KA., Am J Physiol. July 1, 1999; 277 (1): C100-10.

Functional characterization of a novel mutation in KCNA1 in episodic ataxia type 1 associated with epilepsy., Spauschus A, Eunson L, Hanna MG, Kullmann DM., Ann N Y Acad Sci. April 30, 1999; 868 442-6.

Ile-177 and Ser-180 in the S1 segment are critically important in Kv1.1 channel function., Mathur R, Zhou J, Babila T, Koren G., J Biol Chem. April 23, 1999; 274 (17): 11487-93.

Fast inactivation of a brain K+ channel composed of Kv1.1 and Kvbeta1.1 subunits modulated by G protein beta gamma subunits., Jing J, Chikvashvili D, Singer-Lahat D, Thornhill WB, Reuveny E, Lotan I., EMBO J. March 1, 1999; 18 (5): 1245-56.

Transplanting the N-terminus from Kv1.4 to Kv1.1 generates an inwardly rectifying K+ channel., Chanda B, Tiwari JK, Varshney A, Mathew MK., Neuroreport. February 5, 1999; 10 (2): 237-41.

Open channel block and open channel destabilization: contrasting effects of phenol, TEA+ and local anaesthetics on Kv1.1 K+ channels., Elliott AA, Harrold JA, Newman JP, Elliott JR., Toxicol Lett. November 23, 1998; 100-101 277-85.

Selective peptide antagonist of the class E calcium channel from the venom of the tarantula Hysterocrates gigas., Newcomb R, Szoke B, Palma A, Wang G, Chen X, Hopkins W, Cong R, Miller J, Urge L, Tarczy-Hornoch K, Loo JA, Dooley DJ, Nadasdi L, Tsien RW, Lemos J, Miljanich G., Biochemistry. November 3, 1998; 37 (44): 15353-62.

A snake toxin inhibitor of inward rectifier potassium channel ROMK1., Imredy JP, Chen C, MacKinnon R., Biochemistry. October 20, 1998; 37 (42): 14867-74.

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