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Summary Expression Phenotypes Gene Literature (197) GO Terms (5) Nucleotides (130) Proteins (44) Interactants (1264) Wiki
XB--481643

Papers associated with dkk1



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Pinhead signaling regulates mesoderm heterogeneity via FGF receptor-dependent pathway., Ossipova O, Itoh K, Radu A, Ezan J, Sokol SY., Development. January 1, 2020;                                       

ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia., Haas M, Gómez Vázquez JL, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Vleminckx K, Walentek P., Cell Rep. September 24, 2019; 28 (13): 3338-3352.e6.                              

Integration of Wnt and FGF signaling in the Xenopus gastrula at TCF and Ets binding sites shows the importance of short-range repression by TCF in patterning the marginal zone., Kjolby RAS, Truchado-Garcia M, Iruvanti S, Harland RM., Development. August 9, 2019; 146 (15):                           

Mechanistic insights from the LHX1-driven molecular network in building the embryonic head., McMahon R, Sibbritt T, Salehin N, Osteil P, Tam PPL., Dev Growth Differ. June 1, 2019; 61 (5): 327-336.

The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis., Guo Y, Dorn T, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M., Dev Biol. May 1, 2019; 449 (1): 1-13.                                  

Leukemia inhibitory factor signaling in Xenopus embryo: Insights from gain of function analysis and dominant negative mutant of the receptor., Jalvy S, Veschambre P, Fédou S, Rezvani HR, Thézé N, Thiébaud P., Dev Biol. March 15, 2019; 447 (2): 200-213.                                  

Nucleotide receptor P2RY4 is required for head formation via induction and maintenance of head organizer in Xenopus laevis., Harata A, Hirakawa M, Sakuma T, Yamamoto T, Hashimoto C., Dev Growth Differ. February 1, 2019; 61 (2): 186-197.                                

Liver Specification in the Absence of Cardiac Differentiation Revealed by Differential Sensitivity to Wnt/β Catenin Pathway Activation., Haworth K, Samuel L, Black S, Kirilenko P, Latinkic B., Front Physiol. January 1, 2019; 10 155.              

WDR5 regulates left-right patterning via chromatin-dependent and -independent functions., Kulkarni SS, Khokha MK., Development. November 28, 2018; 145 (23):                 

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Ding Y, Colozza G, Sosa EA, Moriyama Y, Rundle S, Salwinski L, De Robertis EM., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.                    

Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner., Devotta A, Hong CS, Saint-Jeannet JP., Elife. July 23, 2018; 7                             

SATB1 downregulation induced by oxidative stress participates in trophoblast invasion by regulating β-catenin., Rao H, Bai Y, Li Q, Zhuang B, Yuan Y, Liu Y, Peng W, Baker PN, Tong C, Luo X, Qi H., Biol Reprod. June 1, 2018; 98 (6): 810-820.

Roles of Xenopus chemokine ligand CXCLh (XCXCLh) in early embryogenesis., Goto T, Ito Y, Michiue T., Dev Growth Differ. May 1, 2018; 60 (4): 226-238.              

Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis., Rankin SA, Rankin SA, McCracken KW, Luedeke DM, Han L, Wells JM, Shannon JM, Zorn AM., Dev Biol. February 1, 2018; 434 (1): 121-132.          

Using Zebrafish to Study Collective Cell Migration in Development and Disease., Olson HM, Nechiporuk AV., Front Cell Dev Biol. January 1, 2018; 6 83.            

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.                                

Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing., Zhang Z, Zhang Z, Jones AE, Wu W, Kim J, Kang Y, Bi X, Gu Y, Popov IK, Renfrow MB, Vassylyeva MN, Vassylyev DG, Giles KE, Chen D, Kumar A, Fan Y, Tong Y, Liu CF, An W, Chang C, Luo J, Chow LT, Wang H., Proc Natl Acad Sci U S A. September 19, 2017; 114 (38): E7949-E7958.                          

Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors., Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, Jin K, Nguyen DM, Sands LR, Marchetti F, Abreu MT, Cobb MH, Capobianco AJ, Lee E, Robbins DJ., Sci Signal. June 27, 2017; 10 (485):


Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula., Ding Y, Colozza G, Zhang K, Moriyama Y, Ploper D, Sosa EA, Benitez MDJ, De Robertis EM., Dev Biol. June 15, 2017; 426 (2): 176-187.                                  

Genome-wide identification of Wnt/β-catenin transcriptional targets during Xenopus gastrulation., Kjolby RAS, Harland RM., Dev Biol. June 15, 2017; 426 (2): 165-175.                                    

The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning., Rauschenberger V, Bernkopf DB, Krenn S, Jalal K, Heller J, Behrens J, Gentzel M, Schambony A., Development. June 15, 2017; 144 (12): 2234-2247.                                      

Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis., Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.                        

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis., Nalesso G, Thomas BL, Sherwood JC, Yu J, Addimanda O, Eldridge SE, Thorup AS, Dale L, Schett G, Zwerina J, Eltawil N, Pitzalis C, Dell'Accio F., Ann Rheum Dis. January 1, 2017; 76 (1): 218-226.              

FoxD1 protein interacts with Wnt and BMP signaling to differentially pattern mesoderm and neural tissue., Polevoy H, Malyarova A, Fonar Y, Elias S, Frank D., Int J Dev Biol. January 1, 2017; 61 (3-4-5): 293-302.              

Apolipoprotein C-I mediates Wnt/Ctnnb1 signaling during neural border formation and is required for neural crest development., Yokota C, Åstrand C, Takahashi S, Hagey DW, Stenman JM., Int J Dev Biol. January 1, 2017; 61 (6-7): 415-425.                      

Cholesterol-rich membrane microdomains modulate Wnt/β-catenin morphogen gradient during Xenopus development., Reis AH, Moreno MM, Maia LA, Oliveira FP, Santos AS, Abreu JG., Mech Dev. November 1, 2016; 142 30-39.                        

Lens regeneration from the cornea requires suppression of Wnt/β-catenin signaling., Hamilton PW, Sun Y, Henry JJ., Exp Eye Res. April 1, 2016; 145 206-215.          

Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling., Zhao Y, Shi J, Winey M, Klymkowsky MW., Dev Biol. March 15, 2016; 411 (2): 257-265.                      

Ventricular cell fate can be specified until the onset of myocardial differentiation., Caporilli S, Latinkic BV., Mech Dev. February 1, 2016; 139 31-41.                        

Specification of anteroposterior axis by combinatorial signaling during Xenopus development., Carron C, Shi DL., Wiley Interdiscip Rev Dev Biol. January 1, 2016; 5 (2): 150-68.            

ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia., Walentek P, Beyer T, Hagenlocher C, Müller C, Feistel K, Schweickert A, Harland RM, Blum M., Dev Biol. December 15, 2015; 408 (2): 292-304.                                

Kruppel-like factor family genes are expressed during Xenopus embryogenesis and involved in germ layer formation and body axis patterning., Gao Y, Cao Q, Lu L, Zhang X, Zhang Z, Zhang Z, Dong X, Jia W, Cao Y, Cao Y., Dev Dyn. October 1, 2015; 244 (10): 1328-46.                                    

JmjC Domain-containing Protein 6 (Jmjd6) Derepresses the Transcriptional Repressor Transcription Factor 7-like 1 (Tcf7l1) and Is Required for Body Axis Patterning during Xenopus Embryogenesis., Zhang X, Gao Y, Lu L, Zhang Z, Zhang Z, Gan S, Xu L, Lei A, Cao Y, Cao Y., J Biol Chem. August 14, 2015; 290 (33): 20273-83.                      

Predicting Variabilities in Cardiac Gene Expression with a Boolean Network Incorporating Uncertainty., Grieb M, Burkovski A, Sträng JE, Kraus JM, Groß A, Palm G, Kühl M, Kestler HA., PLoS One. July 16, 2015; 10 (7): e0131832.        

Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation., Zhang X, Cheong SM, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X., Dev Cell. March 23, 2015; 32 (6): 719-30.                                  

The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Acosta H, Iliev D, Grahn TH, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM., Development. March 15, 2015; 142 (6): 1146-58.                                    

The requirement of histone modification by PRDM12 and Kdm4a for the development of pre-placodal ectoderm and neural crest in Xenopus., Matsukawa S, Miwata K, Asashima M, Michiue T., Dev Biol. March 1, 2015; 399 (1): 164-176.                    

Pax8 and Pax2 are specifically required at different steps of Xenopus pronephros development., Buisson I, Le Bouffant R, Futel M, Riou JF, Umbhauer M., Dev Biol. January 15, 2015; 397 (2): 175-90.                            

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism., Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M., Sci Rep. January 12, 2015; 5 11603.                                  

Transcriptional regulators in the Hippo signaling pathway control organ growth in Xenopus tadpole tail regeneration., Hayashi S, Ochi H, Ogino H, Kawasumi A, Kamei Y, Tamura K, Tamura K, Yokoyama H., Dev Biol. December 1, 2014; 396 (1): 31-41.                      

Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression., Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW., Dev Biol. November 15, 2014; 395 (2): 287-98.                    

Nkx2.5 is involved in myeloid cell differentiation at anterior ventral blood islands in the Xenopus embryo., Sakata H, Maéno M., Dev Growth Differ. October 1, 2014; 56 (8): 544-54.              

Specific induction of cranial placode cells from Xenopus ectoderm by modulating the levels of BMP, Wnt and FGF signaling., Watanabe T, Kanai Y, Matsukawa S, Michiue T., Genesis. October 1, 2014; .

Gene regulatory networks governing lung specification., Rankin SA, Rankin SA, Zorn AM., J Cell Biochem. August 1, 2014; 115 (8): 1343-50.

Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification., Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M., Nat Commun. July 9, 2014; 5 4322.        

Sp8 regulates inner ear development., Chung HA, Medina-Ruiz S, Harland RM., Proc Natl Acad Sci U S A. April 29, 2014; 111 (17): 6329-34.                                                    

Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus., Young JJ, Kjolby RA, Kong NR, Monica SD, Harland RM., Development. April 1, 2014; 141 (8): 1683-93.                                                                

The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength., de Lau W, Peng WC, Gros P, Clevers H., Genes Dev. February 15, 2014; 28 (4): 305-16.          

[New Development in Osteoporosis Treatment. Anti-Dickkopf1 (Dkk1) antibody as a bone anabolic agent for the treatment of osteoporosis]., Tai N, Inoue D., Clin Calcium. January 1, 2014; 24 (1): 75-83.

Circadian genes, xBmal1 and xNocturnin, modulate the timing and differentiation of somites in Xenopus laevis., Curran KL, Allen L, Porter BB, Dodge J, Lope C, Willadsen G, Fisher R, Johnson N, Campbell E, VonBergen B, Winfrey D, Hadley M, Kerndt T., PLoS One. January 1, 2014; 9 (9): e108266.                            

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