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Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis. , Ohkawara B, Glinka A , Niehrs C ., Dev Cell. March 15, 2011; 20 (3): 303-14.
SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos. , Wu MY, Ramel MC, Howell M, Hill CS ., PLoS Biol. February 15, 2011; 9 (2): e1000593.
Wnt/beta-catenin signaling is involved in the induction and maintenance of primitive hematopoiesis in the vertebrate embryo. , Tran HT, Sekkali B, Van Imschoot G, Janssens S , Vleminckx K , Vleminckx K ., Proc Natl Acad Sci U S A. September 14, 2010; 107 (37): 16160-5.
Mesodermal Wnt signaling organizes the neural plate via Meis3. , Elkouby YM, Elias S, Casey ES , Blythe SA , Tsabar N, Klein PS , Root H, Liu KJ , Liu KJ , Frank D ., Development. May 1, 2010; 137 (9): 1531-41.
Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos. , Karaulanov E, Böttcher RT, Stannek P, Wu W, Rau M, Ogata S, Cho KW , Niehrs C ., PLoS One. May 29, 2009; 4 (5): e5742.
The Wnt antagonists Frzb-1 and Crescent locally regulate basement membrane dissolution in the developing primary mouth. , Dickinson AJ , Sive HL ., Development. April 1, 2009; 136 (7): 1071-81.
Differential requirements of BMP and Wnt signalling during gastrulation and neurulation define two steps in neural crest induction. , Steventon B , Araya C, Linker C, Kuriyama S , Mayor R ., Development. March 1, 2009; 136 (5): 771-9.
Fgf8a induces neural crest indirectly through the activation of Wnt8 in the paraxial mesoderm. , Hong CS , Park BY, Saint-Jeannet JP ., Development. December 1, 2008; 135 (23): 3903-10.
The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development. , Kazanskaya O, Ohkawara B, Heroult M, Wu W, Maltry N, Augustin HG, Niehrs C ., Development. November 1, 2008; 135 (22): 3655-64.
Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction. , Pinho S, Niehrs C ., Differentiation. December 1, 2007; 75 (10): 957-67.
Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling. , Hassler C, Cruciat CM, Huang YL, Kuriyama S , Mayor R , Niehrs C ., Development. December 1, 2007; 134 (23): 4255-63.
Integrating patterning signals: Wnt/ GSK3 regulates the duration of the BMP/ Smad1 signal. , Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H , Pera EM , De Robertis EM ., Cell. November 30, 2007; 131 (5): 980-93.
Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development. , McLin VA , Rankin SA , Zorn AM ., Development. June 1, 2007; 134 (12): 2207-17.
Multiple functions of Cerberus cooperate to induce heart downstream of Nodal. , Foley AC , Korol O, Timmer AM, Mercola M ., Dev Biol. March 1, 2007; 303 (1): 57-65.
Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/ beta catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek. , Caneparo L, Huang YL, Staudt N, Tada M , Ahrendt R, Kazanskaya O, Niehrs C , Houart C., Genes Dev. February 15, 2007; 21 (4): 465-80.
FGF is essential for both condensation and mesenchymal-epithelial transition stages of pronephric kidney tubule development. , Urban AE , Zhou X , Zhou X , Ungos JM, Raible DW, Altmann CR , Vize PD ., Dev Biol. September 1, 2006; 297 (1): 103-17.
NARF, an nemo-like kinase ( NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF). , Yamada M, Ohnishi J, Ohkawara B, Iemura S, Satoh K, Hyodo-Miura J, Kawachi K, Natsume T, Shibuya H ., J Biol Chem. July 28, 2006; 281 (30): 20749-20760.
The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition. , Cruciat CM, Hassler C, Niehrs C ., J Biol Chem. May 5, 2006; 281 (18): 12986-93.
Role of crescent in convergent extension movements by modulating Wnt signaling in early Xenopus embryogenesis. , Shibata M , Itoh M, Hikasa H, Taira S , Taira M ., Mech Dev. December 1, 2005; 122 (12): 1322-39.
Antagonistic interaction between IGF and Wnt/ JNK signaling in convergent extension in Xenopus embryo. , Carron C, Bourdelas A, Li HY, Boucaut JC , Shi DL ., Mech Dev. November 1, 2005; 122 (11): 1234-47.
Xenopus hairy2b specifies anterior prechordal mesoderm identity within Spemann's organizer. , Yamaguti M, Cho KW , Hashimoto C., Dev Dyn. September 1, 2005; 234 (1): 102-13.
Xenopus hairy2b specifies anterior prechordal mesoderm identity within Spemann's organizer. , Yamaguti M, Cho KW , Hashimoto C., Dev Dyn. September 1, 2005; 234 (1): 102-13.
The doublesex-related gene, XDmrt4, is required for neurogenesis in the olfactory system. , Huang X , Hong CS , O'Donnell M, Saint-Jeannet JP ., Proc Natl Acad Sci U S A. August 9, 2005; 102 (32): 11349-54.
Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex. , Foley AC , Mercola M ., Genes Dev. February 1, 2005; 19 (3): 387-96.
PP2A:B56epsilon is required for Wnt/beta-catenin signaling during embryonic development. , Yang J , Wu J , Tan C, Klein PS ., Development. December 1, 2003; 130 (23): 5569-78.
Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning. , Davidson G, Mao B , del Barco Barrantes I, Niehrs C ., Development. December 1, 2002; 129 (24): 5587-96.