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Summary Expression Phenotypes Gene Literature (234) GO Terms (11) Nucleotides (370) Proteins (50) Interactants (1557) Wiki
XB--484285

Papers associated with tp53



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RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis., Naert T, Dimitrakopoulou D, Tulkens D, Demuynck S, Carron M, Noelanders R, Eeckhout L, Van Isterdael G, Deforce D, Vanhove C, Van Dorpe J, Creytens D, Vleminckx K, Vleminckx K., Oncogene. March 1, 2020; 39 (13): 2692-2706.          

Dehydration stress alters the mitogen-activated-protein kinase signaling and chaperone stress response in Xenopus laevis., Wu CW, Tessier SN, Storey KB., Comp Biochem Physiol B Biochem Mol Biol. January 1, 2020; 246-247 110461.

Repression of Inappropriate Gene Expression in the Vertebrate Embryonic Ectoderm., Reich S, Weinstein DC., Genes (Basel). November 6, 2019; 10 (11):         

NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress., Han D, Schomacher L, Schüle KM, Mallick M, Musheev MU, Karaulanov E, Krebs L, von Seggern A, Niehrs C., Elife. September 30, 2019; 8                                     

Characteristics of in Vivo Model Systems for Ovarian Cancer Studies., Tudrej P, Kujawa KA, Cortez AJ, Lisowska KM., Diagnostics (Basel). September 14, 2019; 9 (3):         

Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis., Paraiso KD, Blitz IL, Zhou JJ, Cho KWY., Dev Cell. May 20, 2019; 49 (4): 643-650.e3.        

X-linked α-thalassemia with mental retardation is downstream of protein kinase A in the meiotic cell cycle signaling cascade in Xenopus oocytes and is dynamically regulated in response to DNA damage†., O'Shea LC, Fair T, Hensey C., Biol Reprod. May 1, 2019; 100 (5): 1238-1249.

Dissociation Process of a MDM2/p53 Complex Investigated by Parallel Cascade Selection Molecular Dynamics and the Markov State Model., Tran DP, Kitao A., J Phys Chem B. March 21, 2019; 123 (11): 2469-2478.

DNp73-induced degradation of tyrosinase links depigmentation with EMT-driven melanoma progression., Fürst K, Steder M, Logotheti S, Angerilli A, Spitschak A, Marquardt S, Schumacher T, Engelmann D, Herchenröder O, Rupp RAW, Pützer BM., Cancer Lett. February 1, 2019; 442 299-309.

Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M, Zhang H, Zhang G, Zhong A, Ma Q, Kai J, Tong Y, Xie S, Wang Y, Zheng H, Guo L, Lu R., Biochem Biophys Res Commun. December 9, 2018; 507 (1-4): 74-82.          

AKT signaling displays multifaceted functions in neural crest development., Sittewelle M, Monsoro-Burq AH., Dev Biol. December 1, 2018; 444 Suppl 1 S144-S155.

TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT., Zou Z, Zheng B, Li J, Lv X, Zhang H, Yu F, Kong L, Li Y, Yu M, Fang L, Liang B., Biomed Pharmacother. November 1, 2018; 107 1286-1293.

Characterization of a Protein Phosphatase Type-1 and a Kinase Anchoring Protein in Plasmodium falciparum., Lenne A, De Witte C, Tellier G, Hollin T, Aliouat EM, Martoriati A, Cailliau K, Saliou JM, Khalife J, Pierrot C., Front Microbiol. October 31, 2018; 9 2617.              

Photoactivation of MDM2 Inhibitors: Controlling Protein-Protein Interaction with Light., Hansen MJ, Feringa FM, Kobauri P, Szymanski W, Medema RH, Feringa BL., J Am Chem Soc. October 17, 2018; 140 (41): 13136-13141.

Xenopus SOX5 enhances myogenic transcription indirectly through transrepression., Della Gaspera B, Chesneau A, Weill L, Charbonnier F, Chanoine C., Dev Biol. October 15, 2018; 442 (2): 262-275.                    

Identification of Drivers of Aneuploidy in Breast Tumors., Pfister K, Pipka JL, Chiang C, Liu Y, Clark RA, Keller R, Skoglund P, Guertin MJ, Hall IM, Stukenberg PT., Cell Rep. May 29, 2018; 23 (9): 2758-2769.                          

Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus., Gentsch GE, Spruce T, Monteiro RS, Owens NDL, Martin SR, Smith JC., Dev Cell. March 12, 2018; 44 (5): 597-610.e10.                                            

TPX2-p53-GLIPR1 regulatory circuitry in cell proliferation, invasion, and tumor growth of bladder cancer., Yan L, Li Q, Yang J, Qiao B., J Cell Biochem. February 1, 2018; 119 (2): 1791-1803.

Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders., Calo E, Gu B, Bowen ME, Aryan F, Zalc A, Liang J, Flynn RA, Swigut T, Chang HY, Attardi LD, Wysocka J., Nature. February 1, 2018; 554 (7690): 112-117.

Targeted Base Editing via RNA-Guided Cytidine Deaminases in Xenopus laevis Embryos., Park DS, Yoon M, Kweon J, Jang AH, Kim Y, Choi SC., Mol Cells. November 30, 2017; 40 (11): 823-827.    

Regulatory remodeling in the allo-tetraploid frog Xenopus laevis., Elurbe DM, Paranjpe SS, Georgiou G, van Kruijsbergen I, Bogdanovic O, Gibeaux R, Heald R, Lister R, Huynen MA, van Heeringen SJ, Veenstra GJC., Genome Biol. October 24, 2017; 18 (1): 198.              

Two-Element Transcriptional Regulation in the Canonical Wnt Pathway., Kim K, Cho J, Hilzinger TS, Nunns H, Liu A, Ryba BE, Goentoro L., Curr Biol. August 7, 2017; 27 (15): 2357-2364.e5.                

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z, Lei A, Xu L, Chen L, Chen Y, Chen Y, Zhang X, Gao Y, Yang X, Zhang M, Cao Y, Cao Y., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.        

Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2., Scerbo P, Marchal L, Kodjabachian L., Elife. June 27, 2017; 6                               

High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  

The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis., Gao Q, Zhang J, Wang X, Liu Y, He R, Liu X, Wang F, Feng J, Yang D, Wang Z, Meng A, Yan X., Nat Commun. June 7, 2017; 8 15279.              

The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis., Potapova T, Gorbsky GJ., Biology (Basel). February 8, 2017; 6 (1):                 

Shaping Chromatin in the Nucleus: The Bricks and the Architects., Sitbon D, Podsypanina K, Yadav T, Almouzni G., Cold Spring Harb Symp Quant Biol. January 1, 2017; 82 1-14.            

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors., Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Müller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS., Nat Cell Biol. December 1, 2016; 18 (12): 1269-1280.                  

Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2., Dankert JF, Rona G, Clijsters L, Geter P, Skaar JR, Bermudez-Hernandez K, Sassani E, Fenyö D, Ueberheide B, Schneider R, Pagano M., Mol Cell. November 3, 2016; 64 (3): 507-519.

Lethal and sublethal effects of phthalate diesters in Silurana tropicalis larvae., Mathieu-Denoncourt J, Martyniuk CJ, Loughery JR, Yargeau V, de Solla SR, Langlois VS., Environ Toxicol Chem. October 1, 2016; 35 (10): 2511-2522.

Overexpressed targeting protein for Xklp2 (TPX2) serves as a promising prognostic marker and therapeutic target for gastric cancer., Liang B, Zheng W, Fang L, Wu L, Zhou F, Yin X, Yu X, Zou Z., Cancer Biol Ther. August 2, 2016; 17 (8): 824-32.

Alterations in gene expression levels provide early indicators of chemical stress during Xenopus laevis embryo development: A case study with perfluorooctane sulfonate (PFOS)., San-Segundo L, Guimarães L, Fernández Torija C, Beltrán EM, Guilhermino L, Pablos MV., Ecotoxicol Environ Saf. May 1, 2016; 127 51-60.

Recovery capabilities of Xenopus laevis after exposure to Cadmium and Zinc., Mouchet F, Teaniniuraitemoana V, Baudrimont M, Daffe G, Gauthier L, Gonzalez P., Chemosphere. November 1, 2015; 139 117-25.

Cell-fate determination by ubiquitin-dependent regulation of translation., Werner A, Iwasaki S, McGourty CA, Medina-Ruiz S, Teerikorpi N, Fedrigo I, Ingolia NT, Rape M., Nature. September 24, 2015; 525 (7570): 523-7.                            

YAP controls retinal stem cell DNA replication timing and genomic stability., Cabochette P, Vega-Lopez G, Bitard J, Parain K, Chemouny R, Masson C, Borday C, Hedderich M, Henningfeld KA, Locker M, Bronchain O, Perron M., Elife. September 22, 2015; 4 e08488.                                    

The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus., Griffin JN, Sondalle SB, Del Viso F, Baserga SJ, Khokha MK., PLoS Genet. March 10, 2015; 11 (3): e1005018.                              

Evolution of p53 transactivation specificity through the lens of a yeast-based functional assay., Lion M, Raimondi I, Donati S, Jousson O, Ciribilli Y, Inga A., PLoS One. February 10, 2015; 10 (2): e0116177.            

The centrosome and its duplication cycle., Fu J, Hagan IM, Glover DM., Cold Spring Harb Perspect Biol. February 2, 2015; 7 (2): a015800.

Early development of the neural plate: new roles for apoptosis and for one of its main effectors caspase-3., Juraver-Geslin HA, Durand BC., Genesis. February 1, 2015; 53 (2): 203-24.          

Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos., Chernet BT, Fields C, Levin M., Front Physiol. January 19, 2015; 5 519.                

Initiation and maintenance of pluripotency gene expression in the absence of cohesin., Lavagnolli T, Gupta P, Hörmanseder E, Mira-Bontenbal H, Dharmalingam G, Carroll T, Gurdon JB, Fisher AG, Merkenschlager M., Genes Dev. January 1, 2015; 29 (1): 23-38.              

Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish., Pauli A, Montague TG, Lennox KA, Behlke MA, Schier AF., PLoS One. January 1, 2015; 10 (10): e0139504.        

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy., Raymond A, Liu B, Liang H, Wei C, Guindani M, Lu Y, Liang S, St John LS, Molldrem J, Nagarajan L., Oncotarget. December 30, 2014; 5 (24): 12675-93.              

Small ubiquitin-like modifier (SUMO)-mediated repression of the Xenopus Oocyte 5 S rRNA genes., Malik MQ, Bertke MM, Huber PW., J Biol Chem. December 19, 2014; 289 (51): 35468-81.                

The PDZ domain protein Mcc is a novel effector of non-canonical Wnt signaling during convergence and extension in zebrafish., Young T, Poobalan Y, Tan EK, Tao S, Ong S, Wehner P, Schwenty-Lara J, Lim CY, Sadasivam A, Lovatt M, Wang ST, Ali Y, Borchers A, Sampath K, Dunn NR., Development. September 1, 2014; 141 (18): 3505-16.        

Sirtuin inhibitor Ex-527 causes neural tube defects, ventral edema formations, and gastrointestinal malformations in Xenopus laevis embryos., Ohata Y, Matsukawa S, Moriyama Y, Michiue T, Morimoto K, Sato Y, Kuroda H., Dev Growth Differ. August 1, 2014; 56 (6): 460-8.          

TPX2 overexpression in medullary thyroid carcinoma mediates TT cell proliferation., Yang X, Liu G, Xiao H, Yu F, Xiang X, Lu Y, Li W, Liu X, Li S, Shi Y., Pathol Oncol Res. July 1, 2014; 20 (3): 641-8.

Transmembrane voltage potential of somatic cells controls oncogene-mediated tumorigenesis at long-range., Chernet BT, Levin M., Oncotarget. May 30, 2014; 5 (10): 3287-306.              

What's that gene (or protein)? Online resources for exploring functions of genes, transcripts, and proteins., Hutchins JR., Mol Biol Cell. April 1, 2014; 25 (8): 1187-201.    

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