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Summary Expression Phenotypes Gene Literature (550) GO Terms (6) Nucleotides (309) Proteins (58) Interactants (2147) Wiki
XB--485219

Papers associated with otx2 (and morpholino)



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The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins., Li HY, Grifone R, Saquet A, Carron C, Shi DL., Development. December 1, 2013; 140 (24): 4903-13.                                


sox4 and sox11 function during Xenopus laevis eye development., Cizelsky W, Hempel A, Metzig M, Tao S, Hollemann T, Kühl M, Kühl SJ., PLoS One. July 1, 2013; 8 (7): e69372.              


sox4 and sox11 function during Xenopus laevis eye development., Cizelsky W, Hempel A, Metzig M, Tao S, Hollemann T, Kühl M, Kühl SJ., PLoS One. July 1, 2013; 8 (7): e69372.              


Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head., Cases O, Perea-Gomez A, Aguiar DP, Nykjaer A, Amsellem S, Chandellier J, Umbhauer M, Cereghini S, Madsen M, Collignon J, Verroust P, Riou JF, Creuzet SE, Kozyraki R., J Biol Chem. June 7, 2013; 288 (23): 16655-16670.    


The Xenopus doublesex-related gene Dmrt5 is required for olfactory placode neurogenesis., Parlier D, Moers V, Van Campenhout C, Preillon J, Leclère L, Saulnier A, Sirakov M, Busengdal H, Kricha S, Marine JC, Rentzsch F, Bellefroid EJ., Dev Biol. January 1, 2013; 373 (1): 39-52.                              


The Xenopus doublesex-related gene Dmrt5 is required for olfactory placode neurogenesis., Parlier D, Moers V, Van Campenhout C, Preillon J, Leclère L, Saulnier A, Sirakov M, Busengdal H, Kricha S, Marine JC, Rentzsch F, Bellefroid EJ., Dev Biol. January 1, 2013; 373 (1): 39-52.                              


AP-1(c-Jun/FosB) mediates xFoxD5b expression in Xenopus early developmental neurogenesis., Yoon J, Kim JH, Lee OJ, Lee SY, Lee SH, Park JB, Lee JY, Kim SC, Kim J., Int J Dev Biol. January 1, 2013; 57 (11-12): 865-72.        


Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning., Steventon B, Mayor R, Streit A., Dev Biol. July 1, 2012; 367 (1): 55-65.                


Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning., Steventon B, Mayor R, Streit A., Dev Biol. July 1, 2012; 367 (1): 55-65.                


A developmental requirement for HIRA-dependent H3.3 deposition revealed at gastrulation in Xenopus., Szenker E, Lacoste N, Almouzni G., Cell Rep. June 28, 2012; 1 (6): 730-40.                                      


A developmental requirement for HIRA-dependent H3.3 deposition revealed at gastrulation in Xenopus., Szenker E, Lacoste N, Almouzni G., Cell Rep. June 28, 2012; 1 (6): 730-40.                                      


The cytoplasmic tyrosine kinase Arg regulates gastrulation via control of actin organization., Bonacci G, Fletcher J, Devani M, Dwivedi H, Keller R, Chang C., Dev Biol. April 1, 2012; 364 (1): 42-55.                                        


Short chain dehydrogenase/reductase rdhe2 is a novel retinol dehydrogenase essential for frog embryonic development., Belyaeva OV, Lee SA, Adams MK, Chang C, Kedishvili NY., J Biol Chem. March 16, 2012; 287 (12): 9061-71.              


Short chain dehydrogenase/reductase rdhe2 is a novel retinol dehydrogenase essential for frog embryonic development., Belyaeva OV, Lee SA, Adams MK, Chang C, Kedishvili NY., J Biol Chem. March 16, 2012; 287 (12): 9061-71.              


The RNA-binding protein XSeb4R regulates maternal Sox3 at the posttranscriptional level during maternal-zygotic transition in Xenopus., Bentaya S, Ghogomu SM, Vanhomwegen J, Van Campenhout C, Thelie A, Dhainaut M, Bellefroid EJ, Souopgui J., Dev Biol. March 15, 2012; 363 (2): 362-72.                      


Roles of ADAM13-regulated Wnt activity in early Xenopus eye development., Wei S, Xu G, Bridges LC, Williams P, Nakayama T, Shah A, Grainger RM, White JM, DeSimone DW., Dev Biol. March 1, 2012; 363 (1): 147-54.                          


Roles of ADAM13-regulated Wnt activity in early Xenopus eye development., Wei S, Xu G, Bridges LC, Williams P, Nakayama T, Shah A, Grainger RM, White JM, DeSimone DW., Dev Biol. March 1, 2012; 363 (1): 147-54.                          


Maternal xNorrin, a canonical Wnt signaling agonist and TGF-β antagonist, controls early neuroectoderm specification in Xenopus., Xu S, Cheng F, Liang J, Wu W, Zhang J., PLoS Biol. January 1, 2012; 10 (3): e1001286.                                    


A homolog of Subtilisin-like Proprotein Convertase 7 is essential to anterior neural development in Xenopus., Senturker S, Thomas JT, Mateshaytis J, Moos M., PLoS One. January 1, 2012; 7 (6): e39380.                


A homolog of Subtilisin-like Proprotein Convertase 7 is essential to anterior neural development in Xenopus., Senturker S, Thomas JT, Mateshaytis J, Moos M., PLoS One. January 1, 2012; 7 (6): e39380.                


The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo., Min TH, Kriebel M, Hou S, Pera EM., Dev Biol. October 1, 2011; 358 (1): 262-76.                            


The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo., Min TH, Kriebel M, Hou S, Pera EM., Dev Biol. October 1, 2011; 358 (1): 262-76.                            


A novel mechanism for the transcriptional regulation of Wnt signaling in development., Vacik T, Stubbs JL, Lemke G., Genes Dev. September 1, 2011; 25 (17): 1783-95.      


A novel mechanism for the transcriptional regulation of Wnt signaling in development., Vacik T, Stubbs JL, Lemke G., Genes Dev. September 1, 2011; 25 (17): 1783-95.      


Focal adhesion kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate., Fonar Y, Gutkovich YE, Root H, Malyarova A, Aamar E, Golubovskaya VM, Elias S, Elkouby YM, Frank D., Mol Biol Cell. July 1, 2011; 22 (13): 2409-21.                  


Xenopus laevis insulin receptor substrate IRS-1 is important for eye development., Bugner V, Aurhammer T, Kühl M., Dev Dyn. July 1, 2011; 240 (7): 1705-15.            


Xenopus laevis insulin receptor substrate IRS-1 is important for eye development., Bugner V, Aurhammer T, Kühl M., Dev Dyn. July 1, 2011; 240 (7): 1705-15.            


Rab3d is required for Xenopus anterior neurulation by regulating Noggin secretion., Kim H, Han JK., Dev Dyn. June 1, 2011; 240 (6): 1430-9.              


Rab3d is required for Xenopus anterior neurulation by regulating Noggin secretion., Kim H, Han JK., Dev Dyn. June 1, 2011; 240 (6): 1430-9.              


Notch destabilises maternal beta-catenin and restricts dorsal-anterior development in Xenopus., Acosta H, López SL, Revinski DR, Carrasco AE., Development. June 1, 2011; 138 (12): 2567-79.                          


A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer., Rankin SA, Rankin SA, Kormish J, Kofron M, Jegga A, Zorn AM., Dev Biol. March 15, 2011; 351 (2): 297-310.                            


A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer., Rankin SA, Rankin SA, Kormish J, Kofron M, Jegga A, Zorn AM., Dev Biol. March 15, 2011; 351 (2): 297-310.                            


Use of fully modified 2'-O-methyl antisense oligos for loss-of-function studies in vertebrate embryos., Schneider PN, Olthoff JT, Matthews AJ, Houston DW., Genesis. March 1, 2011; 49 (3): 117-23.        


SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos., Wu MY, Ramel MC, Howell M, Hill CS., PLoS Biol. February 15, 2011; 9 (2): e1000593.                              


Polypyrimidine tract-binding protein is required for the repression of gene expression by all-trans retinoic acid., Tamanoue Y, Yamagishi M, Hongo I, Okamoto H., Dev Growth Differ. June 1, 2010; 52 (5): 469-79.                    


Neural crest migration requires the activity of the extracellular sulphatases XtSulf1 and XtSulf2., Guiral EC, Faas L, Pownall ME., Dev Biol. May 15, 2010; 341 (2): 375-88.                              


Neural crest migration requires the activity of the extracellular sulphatases XtSulf1 and XtSulf2., Guiral EC, Faas L, Pownall ME., Dev Biol. May 15, 2010; 341 (2): 375-88.                              


Mesodermal Wnt signaling organizes the neural plate via Meis3., Elkouby YM, Elias S, Casey ES, Blythe SA, Tsabar N, Klein PS, Root H, Liu KJ, Liu KJ, Frank D., Development. May 1, 2010; 137 (9): 1531-41.        


The Pax3 and Pax7 paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos., Maczkowiak F, Matéos S, Wang E, Roche D, Harland R, Monsoro-Burq AH., Dev Biol. April 15, 2010; 340 (2): 381-96.                                                    


The Pax3 and Pax7 paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos., Maczkowiak F, Matéos S, Wang E, Roche D, Harland R, Monsoro-Burq AH., Dev Biol. April 15, 2010; 340 (2): 381-96.                                                    


Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction., Wang Y, Fu Y, Gao L, Zhu G, Liang J, Gao C, Huang B, Fenger U, Niehrs C, Chen YG, Chen YG, Wu W., J Biol Chem. April 2, 2010; 285 (14): 10890-901.                            


Long-term consequences of Sox9 depletion on inner ear development., Park BY, Saint-Jeannet JP., Dev Dyn. April 1, 2010; 239 (4): 1102-12.          


Long-term consequences of Sox9 depletion on inner ear development., Park BY, Saint-Jeannet JP., Dev Dyn. April 1, 2010; 239 (4): 1102-12.          


Secreted factor FAM3C (ILEI) is involved in retinal laminar formation., Katahira T, Nakagiri S, Terada K, Furukawa T., Biochem Biophys Res Commun. February 12, 2010; 392 (3): 301-6.          


FoxO genes are dispensable during gastrulation but required for late embryogenesis in Xenopus laevis., Schuff M, Siegel D, Bardine N, Oswald F, Donow C, Knöchel W., Dev Biol. January 15, 2010; 337 (2): 259-73.                  


FoxO genes are dispensable during gastrulation but required for late embryogenesis in Xenopus laevis., Schuff M, Siegel D, Bardine N, Oswald F, Donow C, Knöchel W., Dev Biol. January 15, 2010; 337 (2): 259-73.                  


BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus., Wills AE, Choi VM, Bennett MJ, Khokha MK, Harland RM., Dev Biol. January 15, 2010; 337 (2): 335-50.                  


BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus., Wills AE, Choi VM, Bennett MJ, Khokha MK, Harland RM., Dev Biol. January 15, 2010; 337 (2): 335-50.                  


Cell cycle control of wnt receptor activation., Davidson G, Shen J, Huang YL, Su Y, Karaulanov E, Bartscherer K, Hassler C, Stannek P, Boutros M, Niehrs C., Dev Cell. December 1, 2009; 17 (6): 788-99.    


The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction., Li B, Kuriyama S, Moreno M, Mayor R., Development. October 1, 2009; 136 (19): 3267-78.            


The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction., Li B, Kuriyama S, Moreno M, Mayor R., Development. October 1, 2009; 136 (19): 3267-78.            


Xmc mediates Xctr1-independent morphogenesis in Xenopus laevis., Haremaki T, Weinstein DC., Dev Dyn. September 1, 2009; 238 (9): 2382-7.            


Mad is required for wingless signaling in wing development and segment patterning in Drosophila., Eivers E, Fuentealba LC, Sander V, Clemens JC, Hartnett L, De Robertis EM., PLoS One. August 6, 2009; 4 (8): e6543.                    


Mad is required for wingless signaling in wing development and segment patterning in Drosophila., Eivers E, Fuentealba LC, Sander V, Clemens JC, Hartnett L, De Robertis EM., PLoS One. August 6, 2009; 4 (8): e6543.                    


Xenopus SMOC-1 Inhibits bone morphogenetic protein signaling downstream of receptor binding and is essential for postgastrulation development in Xenopus., Thomas JT, Canelos P, Luyten FP, Moos M., J Biol Chem. July 10, 2009; 284 (28): 18994-9005.                    


Xenopus SMOC-1 Inhibits bone morphogenetic protein signaling downstream of receptor binding and is essential for postgastrulation development in Xenopus., Thomas JT, Canelos P, Luyten FP, Moos M., J Biol Chem. July 10, 2009; 284 (28): 18994-9005.                    


The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx., Rodríguez-Seguel E, Alarcón P, Gómez-Skarmeta JL., Dev Biol. May 15, 2009; 329 (2): 258-68.                


The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx., Rodríguez-Seguel E, Alarcón P, Gómez-Skarmeta JL., Dev Biol. May 15, 2009; 329 (2): 258-68.                


Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal., Rhinn M, Lun K, Ahrendt R, Geffarth M, Brand M., Neural Dev. April 2, 2009; 4 12.              


A role for Syndecan-4 in neural induction involving ERK- and PKC-dependent pathways., Kuriyama S, Mayor R., Development. February 1, 2009; 136 (4): 575-84.                    


FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination., Dupont S, Mamidi A, Cordenonsi M, Montagner M, Zacchigna L, Adorno M, Martello G, Stinchfield MJ, Soligo S, Morsut L, Inui M, Moro S, Modena N, Argenton F, Newfeld SJ, Piccolo S., Cell. January 9, 2009; 136 (1): 123-35.  


FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination., Dupont S, Mamidi A, Cordenonsi M, Montagner M, Zacchigna L, Adorno M, Martello G, Stinchfield MJ, Soligo S, Morsut L, Inui M, Moro S, Modena N, Argenton F, Newfeld SJ, Piccolo S., Cell. January 9, 2009; 136 (1): 123-35.  


xArx2: an aristaless homolog that regulates brain regionalization during development in Xenopus laevis., Wolanski M, Khosrowshahian F, Kelly LE, El-Hodiri HM, Crawford MJ., Genesis. January 1, 2009; 47 (1): 19-31.              


Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1., Louie SH, Yang XY, Conrad WH, Muster J, Angers S, Moon RT, Cheyette BN., PLoS One. January 1, 2009; 4 (2): e4310.                    


Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1., Louie SH, Yang XY, Conrad WH, Muster J, Angers S, Moon RT, Cheyette BN., PLoS One. January 1, 2009; 4 (2): e4310.                    


Developmental expression and regulation of the chemokine CXCL14 in Xenopus., Park BY, Hong CS, Sohail FA, Saint-Jeannet JP., Int J Dev Biol. January 1, 2009; 53 (4): 535-40.                    


Developmental expression and regulation of the chemokine CXCL14 in Xenopus., Park BY, Hong CS, Sohail FA, Saint-Jeannet JP., Int J Dev Biol. January 1, 2009; 53 (4): 535-40.                    


Hindbrain-derived Wnt and Fgf signals cooperate to specify the otic placode in Xenopus., Park BY, Saint-Jeannet JP., Dev Biol. December 1, 2008; 324 (1): 108-21.      


Hindbrain-derived Wnt and Fgf signals cooperate to specify the otic placode in Xenopus., Park BY, Saint-Jeannet JP., Dev Biol. December 1, 2008; 324 (1): 108-21.      


Hairy2-Id3 interactions play an essential role in Xenopus neural crest progenitor specification., Nichane M, de Crozé N, Ren X, Souopgui J, Monsoro-Burq AH, Bellefroid EJ., Dev Biol. October 15, 2008; 322 (2): 355-67.                          


Hairy2-Id3 interactions play an essential role in Xenopus neural crest progenitor specification., Nichane M, de Crozé N, Ren X, Souopgui J, Monsoro-Burq AH, Bellefroid EJ., Dev Biol. October 15, 2008; 322 (2): 355-67.                          


Extracellular regulation of developmental cell signaling by XtSulf1., Freeman SD, Moore WM, Guiral EC, Holme AD, Turnbull JE, Pownall ME., Dev Biol. August 15, 2008; 320 (2): 436-45.            


Extracellular regulation of developmental cell signaling by XtSulf1., Freeman SD, Moore WM, Guiral EC, Holme AD, Turnbull JE, Pownall ME., Dev Biol. August 15, 2008; 320 (2): 436-45.            


Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning., Ambrosio AL, Taelman VF, Lee HX, Lee HX, Metzinger CA, Coffinier C, De Robertis EM., Dev Cell. August 1, 2008; 15 (2): 248-60.                            


Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning., Ambrosio AL, Taelman VF, Lee HX, Lee HX, Metzinger CA, Coffinier C, De Robertis EM., Dev Cell. August 1, 2008; 15 (2): 248-60.                            


Regulation of TGF-(beta) signalling by N-acetylgalactosaminyltransferase-like 1., Herr P, Korniychuk G, Yamamoto Y, Grubisic K, Oelgeschläger M., Development. May 1, 2008; 135 (10): 1813-22.                    


Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos., Ishibashi H, Matsumura N, Hanafusa H, Matsumoto K, De Robertis EM, Kuroda H., Mech Dev. January 1, 2008; 125 (1-2): 58-66.              


Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos., Ishibashi H, Matsumura N, Hanafusa H, Matsumoto K, De Robertis EM, Kuroda H., Mech Dev. January 1, 2008; 125 (1-2): 58-66.              


Dicer inactivation causes heterochronic retinogenesis in Xenopus laevis., Decembrini S, Andreazzoli M, Barsacchi G, Cremisi F., Int J Dev Biol. January 1, 2008; 52 (8): 1099-103.                


Dicer inactivation causes heterochronic retinogenesis in Xenopus laevis., Decembrini S, Andreazzoli M, Barsacchi G, Cremisi F., Int J Dev Biol. January 1, 2008; 52 (8): 1099-103.                

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