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Summary Expression Phenotypes Gene Literature (192) GO Terms (6) Nucleotides (126) Proteins (56) Interactants (656) Wiki
XB--487965

Papers associated with nkx2-5



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Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs., Stevens ML, Chaturvedi P, Rankin SA, Rankin SA, Macdonald M, Jagannathan S, Yukawa M, Barski A, Zorn AM., Development. April 1, 2017; 144 (7): 1283-1295.                            

FoxD1 protein interacts with Wnt and BMP signaling to differentially pattern mesoderm and neural tissue., Polevoy H, Malyarova A, Fonar Y, Elias S, Frank D., Int J Dev Biol. January 1, 2017; 61 (3-4-5): 293-302.              

The splicing factor SRSF1 modulates pattern formation by inhibiting transcription of tissue specific genes during embryogenesis., Lee SH, Lee HK, Lee HK, Kim C, Kim YK, Ismail T, Jeong Y, Park K, Park JW, Kwon OS, Kang BS, Lee DS, Park MJ, Park DS, Lee HS, Lee HS., Biochem Biophys Res Commun. September 2, 2016; 477 (4): 1011-1016.                

CUG-BP, Elav-like family member 1 (CELF1) is required for normal myofibrillogenesis, morphogenesis, and contractile function in the embryonic heart., Blech-Hermoni Y, Sullivan CB, Jenkins MW, Wessely O, Ladd AN., Dev Dyn. August 1, 2016; 245 (8): 854-73.                      

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification., Rankin SA, Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM., Cell Rep. June 28, 2016; 16 (1): 66-78.                                              

Early ketamine exposure results in cardiac enlargement and heart dysfunction in Xenopus embryos., Guo R, Liu G, Du M, Shi Y, Shi Y, Jiang P, Liu X, Liu L, Liu J, Xu Y, Xu Y., BMC Anesthesiol. April 18, 2016; 16 23.              

pdzrn3 is required for pronephros morphogenesis in Xenopus laevis., Marracci S, Vangelisti A, Raffa V, Andreazzoli M, Dente L., Int J Dev Biol. January 1, 2016; 60 (1-3): 57-63.                  

Perfluoroheptanoic acid affects amphibian embryogenesis by inducing the phosphorylation of ERK and JNK., Kim M, Park MS, Son J, Park I, Lee HK, Kim C, Min BH, Ryoo J, Choi KS, Lee DS, Lee HS., Int J Mol Med. December 1, 2015; 36 (6): 1693-700.

Characterization of ticlopidine-induced developmental and teratogenic defects in Xenopus embryos and human endothelial cells., Park MS, Kim JW, Park I, Lee HK, Kim C, Jo C, Kim YK, Min BH, Ryoo J, Lee DS, Bae JS, Kim SH, Ye SK, Park MJ, Lee HS., Chem Biol Interact. October 5, 2015; 240 172-8.

Predicting Variabilities in Cardiac Gene Expression with a Boolean Network Incorporating Uncertainty., Grieb M, Burkovski A, Sträng JE, Kraus JM, Groß A, Palm G, Kühl M, Kestler HA., PLoS One. July 16, 2015; 10 (7): e0131832.        

Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity., Dorn T, Goedel A, Lam JT, Haas J, Tian Q, Herrmann F, Bundschu K, Dobreva G, Schiemann M, Dirschinger R, Guo Y, Kühl SJ, Sinnecker D, Lipp P, Laugwitz KL, Kühl M, Moretti A., Stem Cells. April 1, 2015; 33 (4): 1113-29.              

The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Acosta H, Iliev D, Grahn TH, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM., Development. March 15, 2015; 142 (6): 1146-58.                                    

Nkx2.5 is involved in myeloid cell differentiation at anterior ventral blood islands in the Xenopus embryo., Sakata H, Maéno M., Dev Growth Differ. October 1, 2014; 56 (8): 544-54.              

Diverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis., Rozario T, Mead PE, DeSimone DW., Mech Dev. August 1, 2014; 133 203-17.                

Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells., Liu Y, Kaneda R, Leja TW, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz RJ, Barahona M, Schneider MD., Stem Cells. June 1, 2014; 32 (6): 1515-26.              

Comparative analysis reveals distinct and overlapping functions of Mef2c and Mef2d during cardiogenesis in Xenopus laevis., Guo Y, Kühl SJ, Pfister AS, Cizelsky W, Denk S, Beer-Molz L, Kühl M., PLoS One. January 17, 2014; 9 (1): e87294.                

A genome-wide survey of maternal and embryonic transcripts during Xenopus tropicalis development., Paranjpe SS, Jacobi UG, van Heeringen SJ, Veenstra GJ., BMC Genomics. November 6, 2013; 14 762.              

In vivo evaluation and comparison of developmental toxicity and teratogenicity of perfluoroalkyl compounds using Xenopus embryos., Kim M, Son J, Park MS, Ji Y, Chae S, Jun C, Bae JS, Kwon TK, Choo YS, Yoon H, Yoon D, Ryoo J, Kim SH, Park MJ, Lee HS., Chemosphere. October 1, 2013; 93 (6): 1153-60.

Tcf21 regulates the specification and maturation of proepicardial cells., Tandon P, Miteva YV, Kuchenbrod LM, Cristea IM, Conlon FL., Development. June 1, 2013; 140 (11): 2409-21.                                

Developmental origins of a novel gut morphology in frogs., Bloom S, Ledon-Rettig C, Infante C, Everly A, Hanken J, Nascone-Yoder N., Evol Dev. May 1, 2013; 15 (3): 213-23.

Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut., Dush MK, Nascone-Yoder NM., Development. April 1, 2013; 140 (7): 1457-66.                      

Islet1-expressing cardiac progenitor cells: a comparison across species., Pandur P, Sirbu IO, Kühl SJ, Philipp M, Kühl M., Dev Genes Evol. March 1, 2013; 223 (1-2): 117-29.          

Regulation of primitive hematopoiesis by class I histone deacetylases., Shah RR, Koniski A, Shinde M, Blythe SA, Fass DM, Haggarty SJ, Palis J, Klein PS., Dev Dyn. February 1, 2013; 242 (2): 108-21.              

Prolonged FGF signaling is necessary for lung and liver induction in Xenopus., Shifley ET, Kenny AP, Rankin SA, Rankin SA, Zorn AM., BMC Dev Biol. September 18, 2012; 12 27.                      

Dissociation of cardiogenic and postnatal myocardial activities of GATA4., Gallagher JM, Komati H, Roy E, Nemer M, Latinkić BV., Mol Cell Biol. June 1, 2012; 32 (12): 2214-23.

Inhibition of heart formation by lithium is an indirect result of the disruption of tissue organization within the embryo., Martin LK, Bratoeva M, Mezentseva NV, Bernanke JM, Remond MC, Ramsdell AF, Eisenberg CA, Eisenberg LM., Dev Growth Differ. February 1, 2012; 54 (2): 153-66.                

Tbx5 overexpression favors a first heart field lineage in murine embryonic stem cells and in Xenopus laevis embryos., Herrmann F, Bundschu K, Kühl SJ, Kühl M., Dev Dyn. December 1, 2011; 240 (12): 2634-45.  

Canonical WNT signaling enhances stem cell expression in the developing heart without a corresponding inhibition of cardiogenic differentiation., Martin LK, Mezentseva NV, Bratoeva M, Ramsdell AF, Eisenberg CA, Eisenberg LM., Stem Cells Dev. November 1, 2011; 20 (11): 1973-83.

Focal adhesion kinase is essential for cardiac looping and multichamber heart formation., Doherty JT, Conlon FL, Mack CP, Taylor JM., Genesis. August 1, 2010; 48 (8): 492-504.                  

Examining the cardiac NK-2 genes in early heart development., Bartlett H, Veenstra GJ, Weeks DL., Pediatr Cardiol. April 1, 2010; 31 (3): 335-41.

FoxO genes are dispensable during gastrulation but required for late embryogenesis in Xenopus laevis., Schuff M, Siegel D, Bardine N, Oswald F, Donow C, Knöchel W., Dev Biol. January 15, 2010; 337 (2): 259-73.                  

Neural ectoderm-secreted FGF initiates the expression of Nkx2.5 in cardiac progenitors via a p38 MAPK/CREB pathway., Keren-Politansky A, Keren A, Bengal E., Dev Biol. November 15, 2009; 335 (2): 374-84.            

Early activation of FGF and nodal pathways mediates cardiac specification independently of Wnt/beta-catenin signaling., Samuel LJ, Latinkić BV., PLoS One. October 28, 2009; 4 (10): e7650.                

Retinoic acid regulates anterior-posterior patterning within the lateral plate mesoderm of Xenopus., Deimling SJ, Drysdale TA., Mech Dev. October 1, 2009; 126 (10): 913-23.                        

NFAT directly regulates Nkx2-5 transcription during cardiac cell differentiation., Chen Y, Chen Y, Cao X., Biol Cell. June 1, 2009; 101 (6): 335-49.

The role of the visceral mesoderm in the development of the gastrointestinal tract., McLin VA, Henning SJ, Jamrich M., Gastroenterology. June 1, 2009; 136 (7): 2074-91.

Mitochondria and calcium signaling in embryonic development., Cao X, Chen Y., Semin Cell Dev Biol. May 1, 2009; 20 (3): 337-45.    

Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5., Espinoza-Lewis RA, Yu L, He F, Liu H, Tang R, Shi J, Sun X, Martin JF, Wang D, Yang J, Chen Y., Dev Biol. March 15, 2009; 327 (2): 376-85.      

Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling., Li Y, Rankin SA, Rankin SA, Sinner D, Kenny AP, Krieg PA, Zorn AM., Genes Dev. November 1, 2008; 22 (21): 3050-63.                        

Cardiac differentiation in Xenopus requires the cyclin-dependent kinase inhibitor, p27Xic1., Movassagh M, Philpott A., Cardiovasc Res. August 1, 2008; 79 (3): 436-47.                                

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis., Zhu W, Shiojima I, Ito Y, Li Z, Ikeda H, Yoshida M, Naito AT, Nishi J, Ueno H, Umezawa A, Minamino T, Nagai T, Kikuchi A, Asashima M, Komuro I., Nature. July 17, 2008; 454 (7202): 345-9.                        

XHAPLN3 plays a key role in cardiogenesis by maintaining the hyaluronan matrix around heart anlage., Ito Y, Seno S, Nakamura H, Fukui A, Asashima M., Dev Biol. July 1, 2008; 319 (1): 34-45.                          

A crucial role of a high mobility group protein HMGA2 in cardiogenesis., Monzen K, Ito Y, Naito AT, Kasai H, Hiroi Y, Hayashi D, Shiojima I, Yamazaki T, Miyazono K, Asashima M, Nagai R, Komuro I., Nat Cell Biol. May 1, 2008; 10 (5): 567-74.                  

HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus., Nagao K, Taniyama Y, Kietzmann T, Doi T, Komuro I, Morishita R., J Biol Chem. April 25, 2008; 283 (17): 11841-9.                        

The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm., Spagnoli FM, Brivanlou AH., Development. February 1, 2008; 135 (3): 451-61.                                                    

Lessons from the lily pad: Using Xenopus to understand heart disease., Bartlett HL, Weeks DL., Drug Discov Today Dis Models. January 1, 2008; 5 (3): 141-146.

Redundancy and evolution of GATA factor requirements in development of the myocardium., Peterkin T, Gibson A, Patient R., Dev Biol. November 15, 2007; 311 (2): 623-35.          

The mitochondrial respiratory chain controls intracellular calcium signaling and NFAT activity essential for heart formation in Xenopus laevis., Chen Y, Yuen WH, Fu J, Huang G, Melendez AJ, Ibrahim FB, Lu H, Cao X., Mol Cell Biol. September 1, 2007; 27 (18): 6420-32.

Transient early embryonic expression of Nkx2-5 mutations linked to congenital heart defects in human causes heart defects in Xenopus laevis., Bartlett HL, Sutherland L, Kolker SJ, Welp C, Tajchman U, Desmarais V, Weeks DL., Dev Dyn. September 1, 2007; 236 (9): 2475-84.    

Left-sided embryonic expression of the BCL-6 corepressor, BCOR, is required for vertebrate laterality determination., Hilton EN, Manson FD, Urquhart JE, Johnston JJ, Slavotinek AM, Hedera P, Stattin EL, Nordgren A, Biesecker LG, Black GC., Hum Mol Genet. July 15, 2007; 16 (14): 1773-82.              

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