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Summary Expression Phenotypes Gene Literature (105) GO Terms (5) Nucleotides (93) Proteins (35) Interactants (862) Wiki
XB--6258962

Papers associated with lefty



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The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis., Gao Q, Zhang J, Wang X, Liu Y, He R, Liu X, Wang F, Feng J, Yang D, Wang Z, Meng A, Yan X., Nat Commun. June 7, 2017; 8 15279.              

Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis., Pitcairn E, Harris H, Epiney J, Pai VP, Lemire JM, Ye B, Shi NQ, Levin M, McLaughlin KA., Commun Integr Biol. May 10, 2017; 10 (3): e1309488.                            

Leftward Flow Determines Laterality in Conjoined Twins., Tisler M, Thumberger T, Schneider I, Schweickert A, Blum M., Curr Biol. February 20, 2017; 27 (4): 543-548.                

Nodal signalling in Xenopus: the role of Xnr5 in left/right asymmetry and heart development., Tadjuidje E, Kofron M, Mir A, Wylie C, Heasman J, Cha SW., Open Biol. August 1, 2016; 6 (8):             

Conserved roles for cytoskeletal components in determining laterality., McDowell GS, Lemire JM, Paré JF, Cammarata G, Lowery LA, Levin M., Integr Biol (Camb). March 14, 2016; 8 (3): 267-86.

The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left-right asymmetry., Endicott SJ, Basu B, Khokha M, Brueckner M., Development. December 1, 2015; 142 (23): 4068-79.                                  

Temporally coordinated signals progressively pattern the anteroposterior and dorsoventral body axes., Tuazon FB, Mullins MC., Semin Cell Dev Biol. June 1, 2015; 42 118-33.

E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation., Wills AE, Baker JC., Dev Cell. February 9, 2015; 32 (3): 345-57.                  

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism., Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M., Sci Rep. January 12, 2015; 5 11603.                                  

Initiation and maintenance of pluripotency gene expression in the absence of cohesin., Lavagnolli T, Gupta P, Hörmanseder E, Mira-Bontenbal H, Dharmalingam G, Carroll T, Gurdon JB, Fisher AG, Merkenschlager M., Genes Dev. January 1, 2015; 29 (1): 23-38.              

Genome-wide view of TGFβ/Foxh1 regulation of the early mesendoderm program., Chiu WT, Charney Le R, Blitz IL, Fish MB, Li Y, Biesinger J, Xie X, Cho KW., Development. December 1, 2014; 141 (23): 4537-47.                                  

Developmental enhancers are marked independently of zygotic Nodal signals in Xenopus., Gupta R, Wills A, Ucar D, Baker J., Dev Biol. November 1, 2014; 395 (1): 38-49.            

Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming., Jullien J, Miyamoto K, Pasque V, Allen GE, Bradshaw CR, Garrett NJ, Halley-Stott RP, Kimura H, Ohsumi K, Gurdon JB., Mol Cell. August 21, 2014; 55 (4): 524-36.              

The chicken left right organizer has nonmotile cilia which are lost in a stage-dependent manner in the talpid(3) ciliopathy., Stephen LA, Johnson EJ, Davis GM, McTeir L, Pinkham J, Jaberi N, Davey MG., Genesis. June 1, 2014; 52 (6): 600-13.            

The evolution and conservation of left-right patterning mechanisms., Blum M, Feistel K, Thumberger T, Schweickert A., Development. April 1, 2014; 141 (8): 1603-13.              

Wave pinning and spatial patterning in a mathematical model of Antivin/Lefty-Nodal signalling., Middleton AM, King JR, Loose M., J Math Biol. December 1, 2013; 67 (6-7): 1393-424.

The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins., Li HY, Grifone R, Saquet A, Carron C, Shi DL., Development. December 1, 2013; 140 (24): 4903-13.                                

Left-right asymmetry: lessons from Cancún., Burdine RD, Caspary T., Development. November 1, 2013; 140 (22): 4465-70.    

It's never too early to get it Right: A conserved role for the cytoskeleton in left-right asymmetry., Vandenberg LN, Lemire JM, Levin M., Commun Integr Biol. November 1, 2013; 6 (6): e27155.          

Dvr1 transfers left-right asymmetric signals from Kupffer's vesicle to lateral plate mesoderm in zebrafish., Peterson AG, Wang X, Yost HJ., Dev Biol. October 1, 2013; 382 (1): 198-208.    

Developmental mechanisms directing early anterior forebrain specification in vertebrates., Andoniadou CL, Martinez-Barbera JP., Cell Mol Life Sci. October 1, 2013; 70 (20): 3739-52.        

TBX3 Directs Cell-Fate Decision toward Mesendoderm., Weidgang CE, Russell R, Tata PR, Kühl SJ, Illing A, Müller M, Lin Q, Brunner C, Boeckers TM, Bauer K, Kartikasari AE, Guo Y, Radenz M, Bernemann C, Weiß M, Seufferlein T, Zenke M, Iacovino M, Kyba M, Schöler HR, Kühl M, Liebau S, Kleger A., Stem Cell Reports. August 29, 2013; 1 (3): 248-65.                

Serotonin has early, cilia-independent roles in Xenopus left-right patterning., Vandenberg LN, Lemire JM, Levin M., Dis Model Mech. January 1, 2013; 6 (1): 261-8.    

Self-regulation of the head-inducing properties of the Spemann organizer., Inui M, Montagner M, Ben-Zvi D, Martello G, Soligo S, Manfrin A, Aragona M, Enzo E, Zacchigna L, Zanconato F, Azzolin L, Dupont S, Cordenonsi M, Piccolo S., Proc Natl Acad Sci U S A. September 18, 2012; 109 (38): 15354-9.                            

RFX2 is broadly required for ciliogenesis during vertebrate development., Chung MI, Peyrot SM, LeBoeuf S, Park TJ, McGary KL, Marcotte EM, Wallingford JB., Dev Biol. March 1, 2012; 363 (1): 155-65.                                                          

BMP inhibition by DAN in Hensen's node is a critical step for the establishment of left-right asymmetry in the chick embryo., Katsu K, Tokumori D, Tatsumi N, Suzuki A, Yokouchi Y., Dev Biol. March 1, 2012; 363 (1): 15-26.

Linking early determinants and cilia-driven leftward flow in left-right axis specification of Xenopus laevis: a theoretical approach., Schweickert A, Walentek P, Thumberger T, Danilchik M., Differentiation. February 1, 2012; 83 (2): S67-77.      

Laterality defects are influenced by timing of treatments and animal model., Vandenberg LN., Differentiation. January 1, 2012; 83 (1): 26-37.          

Neurally Derived Tissues in Xenopus laevis Embryos Exhibit a Consistent Bioelectrical Left-Right Asymmetry., Pai VP, Vandenberg LN, Blackiston D, Levin M., Stem Cells Int. January 1, 2012; 2012 353491.          

HEB and E2A function as SMAD/FOXH1 cofactors., Yoon SJ, Wills AE, Chuong E, Gupta R, Baker JC., Genes Dev. August 1, 2011; 25 (15): 1654-61.            

Essential roles of fibronectin in the development of the left-right embryonic body plan., Pulina MV, Hou SY, Mittal A, Julich D, Whittaker CA, Holley SA, Hynes RO, Astrof S., Dev Biol. June 15, 2011; 354 (2): 208-20.

APOBEC2, a selective inhibitor of TGFβ signaling, regulates left-right axis specification during early embryogenesis., Vonica A, Rosa A, Arduini BL, Brivanlou AH., Dev Biol. February 1, 2011; 350 (1): 13-23.                

Rapid differential transport of Nodal and Lefty on sulfated proteoglycan-rich extracellular matrix regulates left-right asymmetry in Xenopus., Marjoram L, Wright C., Development. February 1, 2011; 138 (3): 475-85.            

Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway., Luxardi G, Marchal L, Thomé V, Kodjabachian L., Development. February 1, 2010; 137 (3): 417-26.          

The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection., Rosa A, Spagnoli FM, Brivanlou AH., Dev Cell. April 1, 2009; 16 (4): 517-27.    

Transcriptional response of Mexican axolotls to Ambystoma tigrinum virus (ATV) infection., Cotter JD, Storfer A, Page RB, Beachy CK, Voss SR., BMC Genomics. October 20, 2008; 9 493.      

Long-range action of Nodal requires interaction with GDF1., Tanaka C, Sakuma R, Nakamura T, Hamada H, Saijoh Y., Genes Dev. December 15, 2007; 21 (24): 3272-82.        

Xenopus Lefty requires proprotein cleavage but not N-linked glycosylation to inhibit nodal signaling., Westmoreland JJ, Takahashi S, Wright CV., Dev Dyn. August 1, 2007; 236 (8): 2050-61.        

Evolution of axis specification mechanisms in jawed vertebrates: insights from a chondrichthyan., Coolen M, Sauka-Spengler T, Nicolle D, Le-Mentec C, Lallemand Y, Da Silva C, Plouhinec JL, Robert B, Wincker P, Shi DL, Mazan S., PLoS One. April 18, 2007; 2 (4): e374.              

The left-right axis is regulated by the interplay of Coco, Xnr1 and derrière in Xenopus embryos., Vonica A, Brivanlou AH., Dev Biol. March 1, 2007; 303 (1): 281-94.              

Anteriorward shifting of asymmetric Xnr1 expression and contralateral communication in left-right specification in Xenopus., Ohi Y, Wright CV., Dev Biol. January 15, 2007; 301 (2): 447-63.

Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., Rana AA, Collart C, Gilchrist MJ, Smith JC., PLoS Genet. November 17, 2006; 2 (11): e193.                                    

Subtilisin-like proprotein convertase activity is necessary for left-right axis determination in Xenopus neurula embryos., Toyoizumi R, Takeuchi S, Mogi K., Dev Genes Evol. October 1, 2006; 216 (10): 607-22.

Inhibitor-resistant type I receptors reveal specific requirements for TGF-beta signaling in vivo., Ho DM, Chan J, Bayliss P, Whitman M., Dev Biol. July 15, 2006; 295 (2): 730-42.            

Nodal-related gene Xnr5 is amplified in the Xenopus genome., Takahashi S, Onuma Y, Yokota C, Westmoreland JJ, Asashima M, Wright CV., Genesis. July 1, 2006; 44 (7): 309-21.          

Formation of the ascidian epidermal sensory neurons: insights into the origin of the chordate peripheral nervous system., Pasini A, Amiel A, Rothbächer U, Roure A, Lemaire P, Darras S., PLoS Biol. July 1, 2006; 4 (7): e225.              

Cooperative non-cell and cell autonomous regulation of Nodal gene expression and signaling by Lefty/Antivin and Brachyury in Xenopus., Cha YR, Takahashi S, Wright CV., Dev Biol. February 15, 2006; 290 (2): 246-64.                        

The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo., Chen C, Ware SM, Sato A, Houston-Hawkins DE, Habas R, Matzuk MM, Shen MM, Brown CW., Development. January 1, 2006; 133 (2): 319-29.              

XCR2, one of three Xenopus EGF-CFC genes, has a distinct role in the regulation of left-right patterning., Onuma Y, Yeo CY, Whitman M., Development. January 1, 2006; 133 (2): 237-50.                                      

Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis., Bisgrove BW, Snarr BS, Emrazian A, Yost HJ., Dev Biol. November 15, 2005; 287 (2): 274-88.

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