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Summary Expression Phenotypes Gene Literature (456) GO Terms (15) Nucleotides (103) Proteins (33) Interactants (2052) Wiki
XB--488038

Papers associated with shh



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Neural tube closure requires Dishevelled-dependent convergent extension of the midline., Wallingford JB, Harland RM., Development. December 1, 2002; 129 (24): 5815-25.        

Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity., Persson M, Stamataki D, te Welscher P, Andersson E, Böse J, Rüther U, Ericson J, Briscoe J., Genes Dev. November 15, 2002; 16 (22): 2865-78.

A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord., Wijgerde M, McMahon JA, Rule M, McMahon AP., Genes Dev. November 15, 2002; 16 (22): 2849-64.

Mouse GLI3 regulates Fgf8 expression and apoptosis in the developing neural tube, face, and limb bud., Aoto K, Nishimura T, Eto K, Motoyama J., Dev Biol. November 15, 2002; 251 (2): 320-32.

Anteroposterior axis formation in Xenopus limb bud recombinants: a model of pattern formation during limb regeneration., Yokoyama H, Tamura K, Tamura K, Ide H., Dev Dyn. November 1, 2002; 225 (3): 277-88.          

Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney., Yu J, Carroll TJ, McMahon AP., Development. November 1, 2002; 129 (22): 5301-12.

Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning., Levin M, Thorlin T, Robinson KR, Nogi T, Mercola M., Cell. October 4, 2002; 111 (1): 77-89.              

Dual origin of the floor plate in the avian embryo., Charrier JB, Lapointe F, Le Douarin NM, Teillet MA., Development. October 1, 2002; 129 (20): 4785-96.          

Sonic hedgehog rescues cranial neural crest from cell death induced by ethanol exposure., Ahlgren SC, Thakur V, Bronner-Fraser M., Proc Natl Acad Sci U S A. August 6, 2002; 99 (16): 10476-81.

Conserved expression control and shared activity between cognate T-box genes Tbx2 and Tbx3 in connection with Sonic hedgehog signaling during Xenopus eye development., Takabatake Y, Takabatake T, Sasagawa S, Takeshima K., Dev Growth Differ. August 1, 2002; 44 (4): 257-71.              

GLI3 is not mutated commonly in sporadic medulloblastomas., Erez A, Ilan T, Amariglio N, Muler I, Brok-Simoni F, Rechavi G, Izraeli S., Cancer. July 1, 2002; 95 (1): 28-31.

Axes establishment during eye morphogenesis in Xenopus by coordinate and antagonistic actions of BMP4, Shh, and RA., Sasagawa S, Takabatake T, Takabatake Y, Muramatsu T, Takeshima K., Genesis. June 1, 2002; 33 (2): 86-96.                      

A novel Xenopus Smad-interacting forkhead transcription factor (XFast-3) cooperates with XFast-1 in regulating gastrulation movements., Howell M, Inman GJ, Hill CS., Development. June 1, 2002; 129 (12): 2823-34.    

Sonic hedgehog and the molecular regulation of mouse neural tube closure., Ybot-Gonzalez P, Cogram P, Gerrelli D, Copp AJ., Development. May 1, 2002; 129 (10): 2507-17.

Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus., Jia J, Amanai K, Wang G, Tang J, Wang B, Jiang J., Nature. April 4, 2002; 416 (6880): 548-52.

Overexpression of the secreted factor Mig30 expressed in the Spemann organizer impairs morphogenetic movements during Xenopus gastrulation., Hayata T, Tanegashima K, Takahashi S, Sogame A, Asashima M., Mech Dev. March 1, 2002; 112 (1-2): 37-51.                

Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling., te Welscher P, Fernandez-Teran M, Ros MA, Zeller R., Genes Dev. February 15, 2002; 16 (4): 421-6.

Hedgehog signaling in gastrointestinal development and disease., Harmon EB, Ko AH, Kim SK., Curr Mol Med. February 1, 2002; 2 (1): 67-82.

Developmental basis of limb evolution., Hinchliffe JR., Int J Dev Biol. January 1, 2002; 46 (7): 835-45.

Limb development in a "nonmodel" vertebrate, the direct-developing frog Eleutherodactylus coqui., Hanken J, Carl TF, Richardson MK, Olsson L, Schlosser G, Osabutey CK, Klymkowsky MW., J Exp Zool. December 15, 2001; 291 (4): 375-88.

Thyroid hormone-induced expression of sonic hedgehog correlates with adult epithelial development during remodeling of the Xenopus stomach and intestine., Ishizuya-Oka A, Ueda S, Inokuchi T, Amano T, Damjanovski S, Stolow M, Shi YB, Shi YB., Differentiation. December 1, 2001; 69 (1): 27-37.                

Gli1 can rescue the in vivo function of Gli2., Bai CB, Joyner AL., Development. December 1, 2001; 128 (24): 5161-72.

The Alzheimer-related gene presenilin-1 facilitates sonic hedgehog expression in Xenopus primary neurogenesis., Paganelli AR, Ocaña OH, Prat MI, Franco PG, López SL, Morelli L, Adamo AM, Riccomagno MM, Matsubara E, Shoji M, Affranchino JL, Castaño EM, Carrasco AE., Mech Dev. September 1, 2001; 107 (1-2): 119-31.      

Anorectal malformations caused by defects in sonic hedgehog signaling., Mo R, Kim JH, Zhang J, Chiang C, Hui CC, Kim PC., Am J Pathol. August 1, 2001; 159 (2): 765-74.

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node., Zhang XM, Ramalho-Santos M, McMahon AP., Cell. July 27, 2001; 106 (2): 781-92.

Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains., Dann CE, Hsieh JC, Rattner A, Sharma D, Nathans J, Leahy DJ., Nature. July 5, 2001; 412 (6842): 86-90.

Laser-mediated microdissection of paraffin sections from Xenopus embryos allows detection of tissue-specific expressed mRNAs., Imamichi Y, Lahr G, Wedlich D., Dev Genes Evol. July 1, 2001; 211 (7): 361-6.

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node., Zhang XM, Ramalho-Santos M, McMahon AP., Cell. June 15, 2001; 105 (6): 781-92.

Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1., Lewis PM, Dunn MP, McMahon JA, Logan M, Martin JF, St-Jacques B, McMahon AP., Cell. June 1, 2001; 105 (5): 599-612.

Notochord patterning of the endoderm., Cleaver O, Krieg PA., Dev Biol. June 1, 2001; 234 (1): 1-12.      

Patched1 interacts with cyclin B1 to regulate cell cycle progression., Barnes EA, Kong M, Ollendorff V, Donoghue DJ., EMBO J. May 1, 2001; 20 (9): 2214-23.

FGF-10 stimulates limb regeneration ability in Xenopus laevis., Yokoyama H, Ide H, Tamura K, Tamura K., Dev Biol. May 1, 2001; 233 (1): 72-9.      

In synergy with noggin and follistatin, Xenopus nodal-related gene induces sonic hedgehog on notochord and floor plate., Ito Y, Kuhara S, Tashiro K., Biochem Biophys Res Commun. March 2, 2001; 281 (3): 714-9.      

Molecular cloning and expression analysis of the Hedgehog receptors XPtc1 and XSmo in Xenopus laevis., Koebernick K, Hollemann T, Pieler T., Mech Dev. February 1, 2001; 100 (2): 303-8.  

Foregut endoderm is required at head process stages for anteriormost neural patterning in chick., Withington S, Beddington R, Cooke J., Development. February 1, 2001; 128 (3): 309-20.

Molecular aspects of healing in stabilized and non-stabilized fractures., Le AX, Miclau T, Hu D, Helms JA., J Orthop Res. January 1, 2001; 19 (1): 78-84.

Molecular mechanisms of cell-cell signaling by the Spemann-Mangold organizer., De Robertis EM, Wessely O, Oelgeschläger M, Brizuela B, Pera E, Larraín J, Abreu J, Bachiller D., Int J Dev Biol. January 1, 2001; 45 (1): 189-97.        

Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus., Zhang J, Rosenthal A, de Sauvage FJ, Shivdasani RA., Dev Biol. January 1, 2001; 229 (1): 188-202.                  

Xrel3 is required for head development in Xenopus laevis., Lake BB, Ford R, Kao KR., Development. January 1, 2001; 128 (2): 263-73.

Involvement of frizzled-10 in Wnt-7a signaling during chick limb development., Kawakami Y, Wada N, Nishimatsu S, Nohno T., Dev Growth Differ. December 1, 2000; 42 (6): 561-9.  

Hexokinase I is a Gli2-responsive gene expressed in the embryonic CNS., Brewster R, Ruiz i Altaba A., Mech Dev. December 1, 2000; 99 (1-2): 159-62.  

Different activities of the frizzled-related proteins frzb2 and sizzled2 during Xenopus anteroposterior patterning., Bradley L, Sun B, Collins-Racie L, LaVallie E, McCoy J, Sive H., Dev Biol. November 1, 2000; 227 (1): 118-32.                    

Similar expression and regulation of Gli2 and Gli3 in the chick limb bud., Schweitzer R, Vogan KJ, Tabin CJ., Mech Dev. November 1, 2000; 98 (1-2): 171-4.

Distinct expression of two types of Xenopus Patched genes during early embryogenesis and hindlimb development., Takabatake T, Takahashi TC, Takabatake Y, Yamada K, Ogawa M, Takeshima K., Mech Dev. November 1, 2000; 98 (1-2): 99-104.            

The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning., Kazanskaya O, Glinka A, Niehrs C., Development. November 1, 2000; 127 (22): 4981-92.              

The sonic hedgehog-patched-gli pathway in human development and disease., Villavicencio EH, Walterhouse DO, Iannaccone PM., Am J Hum Genet. November 1, 2000; 67 (5): 1047-54.

Multiple stage-dependent roles for histone deacetylases during amphibian embryogenesis: implications for the involvement of extracellular matrix remodeling., Damjanovski S, Sachs LM, Shi YB, Shi YB., Int J Dev Biol. October 1, 2000; 44 (7): 769-76.                    

Regulation of gli activity by all-trans retinoic acid in mouse keratinocytes., Goyette P, Allan D, Peschard P, Chen CF, Wang W, Lohnes D., Cancer Res. October 1, 2000; 60 (19): 5386-9.

Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3., Litingtung Y, Chiang C., Nat Neurosci. October 1, 2000; 3 (10): 979-85.

Gli2 functions in FGF signaling during antero-posterior patterning., Brewster R, Mullor JL, Ruiz i Altaba A., Development. October 1, 2000; 127 (20): 4395-405.            

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