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Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex. , Kundu LR, Kumata Y, Kakusho N, Watanabe S, Furukohri A, Waga S, Seki M, Masai H, Enomoto T, Tada S., Nucleic Acids Res. September 1, 2010; 38 (16): 5409-18.
GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication. , Balestrini A, Cosentino C, Errico A, Garner E, Costanzo V., Nat Cell Biol. May 1, 2010; 12 (5): 484-91.
Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding. , Pascreau G, Eckerdt F, Churchill ME, Maller JL ., Proc Natl Acad Sci U S A. February 16, 2010; 107 (7): 2932-7.
Treslin collaborates with TopBP1 in triggering the initiation of DNA replication. , Kumagai A , Shevchenko A, Shevchenko A, Dunphy WG ., Cell. February 5, 2010; 140 (3): 349-59.
A bifunctional regulatory element in human somatic Wee1 mediates cyclin A/ Cdk2 binding and Crm1-dependent nuclear export. , Li C, Andrake M, Dunbrack R, Enders GH., Mol Cell Biol. January 1, 2010; 30 (1): 116-30.
Identification of substrates for cyclin dependent kinases. , Errico A, Deshmukh K, Tanaka Y, Pozniakovsky A, Hunt T ., Adv Enzyme Regul. January 1, 2010; 50 (1): 375-99.
Replication initiation complex formation in the absence of nuclear function in Xenopus. , Krasinska L, Fisher D ., Nucleic Acids Res. April 1, 2009; 37 (7): 2238-48.
G2 acquisition by transcription-independent mechanism at the zebrafish midblastula transition. , Dalle Nogare DE, Pauerstein PT, Lane ME., Dev Biol. February 1, 2009; 326 (1): 131-42.
Cyclin E in centrosome duplication and reduplication in sea urchin zygotes. , Schnackenberg BJ, Marzluff WF, Sluder G., J Cell Physiol. December 1, 2008; 217 (3): 626-31.
Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation. , Ruiz EJ, Hunt T , Nebreda AR., Mol Cell. October 24, 2008; 32 (2): 210-20.
Cyclin E-dependent localization of MCM5 regulates centrosome duplication. , Ferguson RL, Maller JL ., J Cell Sci. October 1, 2008; 121 (Pt 19): 3224-32.
Selective chemical inhibition as a tool to study Cdk1 and Cdk2 functions in the cell cycle. , Krasinska L, Cot E, Fisher D ., Cell Cycle. June 15, 2008; 7 (12): 1702-8.
Chk1 is activated at the midblastula transition in Xenopus laevis embryos independently of DNA content and the cyclin E/ Cdk2 developmental timer. , Adjerid N, Wroble BN , Sible JC ., Cell Cycle. April 15, 2008; 7 (8): 1112-6.
Plx1 is required for chromosomal DNA replication under stressful conditions. , Trenz K, Errico A, Costanzo V., EMBO J. March 19, 2008; 27 (6): 876-85.
Negative regulation of cell-cycle progression by RINGO/ Speedy E. , Dinarina A, Ruiz EJ, O'Loghlen A, Mouron S, Perez L, Nebreda AR., Biochem J. March 15, 2008; 410 (3): 535-42.
Cdk1 and Cdk2 activity levels determine the efficiency of replication origin firing in Xenopus. , Krasinska L, Besnard E, Cot E, Dohet C, Méchali M, Lemaitre JM, Fisher D ., EMBO J. March 5, 2008; 27 (5): 758-69.
Wee1 kinase alters cyclin E/ Cdk2 and promotes apoptosis during the early embryonic development of Xenopus laevis. , Wroble BN , Finkielstein CV , Sible JC ., BMC Dev Biol. October 25, 2007; 7 119.
Anti-breast cancer activity of LFM-A13, a potent inhibitor of Polo-like kinase ( PLK). , Uckun FM, Dibirdik I, Qazi S, Vassilev A, Ma H, Mao C, Benyumov A, Emami KH., Bioorg Med Chem. January 15, 2007; 15 (2): 800-14.
Nucleocytoplasmic shuttling of bovine papillomavirus E1 helicase downregulates viral DNA replication in S phase. , Hsu CY, Mechali F, Bonne-Andrea C., J Virol. January 1, 2007; 81 (1): 384-94.
Metaphase arrest by cyclin E- Cdk2 requires the spindle-checkpoint kinase Mps1. , Grimison B, Liu J , Lewellyn AL, Maller JL ., Curr Biol. October 10, 2006; 16 (19): 1968-73.
Cyclin A1/ Cdk2 is sufficient but not required for the induction of apoptosis in early Xenopus laevis embryos. , Carter AD, Wroble BN , Sible JC ., Cell Cycle. October 1, 2006; 5 (19): 2230-6.
Meiotic regulation of the CDK activator RINGO/ Speedy by ubiquitin-proteasome-mediated processing and degradation. , Gutierrez GJ, Vögtlin A, Castro A, Ferby I, Salvagiotto G, Ronai Z, Lorca T, Nebreda AR., Nat Cell Biol. October 1, 2006; 8 (10): 1084-94.
Mechanistic studies of the mitotic activation of Mos. , Yue J, Ferrell JE ., Mol Cell Biol. July 1, 2006; 26 (14): 5300-9.
CDK activation by non-cyclin proteins. , Nebreda AR., Curr Opin Cell Biol. April 1, 2006; 18 (2): 192-8.
Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint. , Petersen P, Chou DM, You Z, Hunter T, Walter JC , Walter G., Mol Cell Biol. March 1, 2006; 26 (5): 1997-2011.
Ubiquitination of cyclin-dependent kinase inhibitor, Xic1, is mediated by the Xenopus F-box protein xSkp2. , Lin HR, Chuang LC, Boix-Perales H, Philpott A , Yew PR., Cell Cycle. February 1, 2006; 5 (3): 304-14.
ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha. , Dong Z, Tomkinson AE., Nucleic Acids Res. January 1, 2006; 34 (20): 5721-279.
Proliferating cell nuclear antigen recruits cyclin-dependent kinase inhibitor Xic1 to DNA and couples its proteolysis to DNA polymerase switching. , Chuang LC, Yew PR., J Biol Chem. October 21, 2005; 280 (42): 35299-309.
The C-terminal domain of the Xenopus cyclin-dependent kinase inhibitor, p27Xic1, is both necessary and sufficient for phosphorylation-independent proteolysis. , Chuang LC, Zhu XN, Herrera CR, Tseng HM, Pfleger CM, Block K, Yew PR., J Biol Chem. October 21, 2005; 280 (42): 35290-8.
Biochemical characterization of Cdk2- Speedy/ Ringo A2. , Cheng A, Gerry S, Kaldis P, Solomon MJ ., BMC Biochem. September 28, 2005; 6 19.
A novel Cdk2 interactor is phosphorylated by Cdc7 and associates with components of the replication complexes. , Grishina I, Lattes B., Cell Cycle. August 1, 2005; 4 (8): 1120-6.
Over-expression of Aurora-A targets cytoplasmic polyadenylation element binding protein and promotes mRNA polyadenylation of Cdk1 and cyclin B1. , Sasayama T, Marumoto T, Kunitoku N, Zhang D, Tamaki N, Kohmura E, Saya H, Hirota T., Genes Cells. July 1, 2005; 10 (7): 627-38.
Characterization of a new family of cyclin-dependent kinase activators. , Dinarina A, Perez LH, Davila A, Schwab M, Hunt T , Nebreda AR., Biochem J. March 1, 2005; 386 (Pt 2): 349-55.
Cdk2 activity is essential for the first to second meiosis transition in porcine oocytes. , Sugiura K, Naito K, Tojo H., J Reprod Dev. February 1, 2005; 51 (1): 143-9.
ATM and ATR check in on origins: a dynamic model for origin selection and activation. , Shechter D , Gautier J ., Cell Cycle. February 1, 2005; 4 (2): 235-8.
Identification and comparative analysis of multiple mammalian Speedy/ Ringo proteins. , Cheng A, Xiong W, Ferrell JE , Solomon MJ ., Cell Cycle. January 1, 2005; 4 (1): 155-65.
Methods for preparation of proteins and protein complexes that regulate the eukaryotic cell cycle for structural studies. , Welburn J, Endicott J., Methods Mol Biol. January 1, 2005; 296 219-35.
Identification of Xenopus cyclin-dependent kinase inhibitors, p16Xic2 and p17Xic3. , Daniels M, Dhokia V, Richard-Parpaillon L , Ohnuma S ., Gene. November 10, 2004; 342 (1): 41-7.
Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex. , Takahashi TS, Yiu P, Chou MF, Gygi S, Walter JC ., Nat Cell Biol. October 1, 2004; 6 (10): 991-6.
Chk1, but not Chk2, inhibits Cdc25 phosphatases by a novel common mechanism. , Uto K, Inoue D, Shimuta K, Nakajo N, Sagata N ., EMBO J. August 18, 2004; 23 (16): 3386-96.
ATR and ATM regulate the timing of DNA replication origin firing. , Shechter D , Costanzo V, Gautier J ., Nat Cell Biol. July 1, 2004; 6 (7): 648-55.
G1/S phase cyclin-dependent kinase overexpression perturbs early development and delays tissue-specific differentiation in Xenopus. , Richard-Parpaillon L , Cosgrove RA, Devine C, Vernon AE, Philpott A ., Development. June 1, 2004; 131 (11): 2577-86.
Cyclin A/ Cdk2 complexes regulate activation of Cdk1 and Cdc25 phosphatases in human cells. , Mitra J, Enders GH., Oncogene. April 22, 2004; 23 (19): 3361-7.
Inhibition of the cell cycle is required for convergent extension of the paraxial mesoderm during Xenopus neurulation. , Leise WF, Mueller PR ., Development. April 1, 2004; 131 (8): 1703-15.
When the checkpoints have gone: insights into Cdc25 functional activation. , Margolis SS, Kornbluth S ., Cell Cycle. April 1, 2004; 3 (4): 425-8.
Cdk1: unsung hero of S phase? , Pacek M, Prokhorova TA, Walter JC ., Cell Cycle. April 1, 2004; 3 (4): 401-3.
DNA replication of mitotic chromatin in Xenopus egg extracts. , Prokhorova TA, Mowrer K, Gilbert CH, Walter JC ., Proc Natl Acad Sci U S A. November 11, 2003; 100 (23): 13241-6.
PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation. , Margolis SS, Walsh S, Weiser DC, Yoshida M, Shenolikar S, Kornbluth S ., EMBO J. November 3, 2003; 22 (21): 5734-45.
Spy1 interacts with p27Kip1 to allow G1/S progression. , Porter LA, Kong-Beltran M, Donoghue DJ., Mol Biol Cell. September 1, 2003; 14 (9): 3664-74.
A kinetic model of the cyclin E/ Cdk2 developmental timer in Xenopus laevis embryos. , Ciliberto A, Petrus MJ, Tyson JJ, Sible JC ., Biophys Chem. July 1, 2003; 104 (3): 573-89.