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Summary Expression Phenotypes Gene Literature (274) GO Terms (17) Nucleotides (1482) Proteins (65) Interactants (654) Wiki
XB--489467

Papers associated with ran



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Reconstitution of the augmin complex provides insights into its architecture and function., Hsia KC, Wilson-Kubalek EM, Dottore A, Hao Q, Tsai KL, Forth S, Shimamoto Y, Milligan RA, Kapoor TM., Nat Cell Biol. September 1, 2014; 16 (9): 852-63.

cPKC regulates interphase nuclear size during Xenopus development., Edens LJ, Levy DL., J Cell Biol. August 18, 2014; 206 (4): 473-83.          

TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts., Helmke KJ, Heald R., J Cell Biol. August 4, 2014; 206 (3): 385-93.          

Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters., Johnson ZL, Lee JH, Lee K, Lee M, Kwon DY, Hong J, Lee SY., Elife. July 31, 2014; 3 e03604.                        

Deep proteomics of the Xenopus laevis egg using an mRNA-derived reference database., Wühr M, Freeman RM, Presler M, Horb ME, Peshkin L, Gygi S, Kirschner MW., Curr Biol. July 7, 2014; 24 (13): 1467-1475.          

Nucleosomal regulation of chromatin composition and nuclear assembly revealed by histone depletion., Zierhut C, Jenness C, Kimura H, Funabiki H., Nat Struct Mol Biol. July 1, 2014; 21 (7): 617-25.

The Virtual Xenbase: transitioning an online bioinformatics resource to a private cloud., Karimi K, Vize PD., Database (Oxford). April 4, 2014; 2014     

Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration., Bernis C, Swift-Taylor B, Nord M, Carmona S, Chook YM, Forbes DJ., Mol Biol Cell. April 1, 2014; 25 (7): 992-1009.                  

p54nrb/NonO and PSF promote U snRNA nuclear export by accelerating its export complex assembly., Izumi H, McCloskey A, Shinmyozu K, Ohno M., Nucleic Acids Res. April 1, 2014; 42 (6): 3998-4007.          

The nucleoporin MEL-28 promotes RanGTP-dependent γ-tubulin recruitment and microtubule nucleation in mitotic spindle formation., Yokoyama H, Koch B, Walczak R, Ciray-Duygu F, González-Sánchez JC, Devos DP, Mattaj IW, Gruss OJ., Nat Commun. January 1, 2014; 5 3270.

Glycogen-supplemented mitotic cytosol for analyzing Xenopus egg microtubule organization., Groen AC, Ngyuen PA, Field CM, Ishihara K, Mitchison TJ., Methods Enzymol. January 1, 2014; 540 417-33.

CHD4 is a RanGTP-dependent MAP that stabilizes microtubules and regulates bipolar spindle formation., Yokoyama H, Nakos K, Santarella-Mellwig R, Rybina S, Krijgsveld J, Koffa MD, Mattaj IW., Curr Biol. December 16, 2013; 23 (24): 2443-51.                      

Promiscuous activation of transient receptor potential vanilloid 1 (TRPV1) channels by negatively charged intracellular lipids: the key role of endogenous phosphoinositides in maintaining channel activity., Lukacs V, Rives JM, Sun X, Zakharian E, Rohacs T., J Biol Chem. December 6, 2013; 288 (49): 35003-13.

Par3 controls neural crest migration by promoting microtubule catastrophe during contact inhibition of locomotion., Moore R, Theveneau E, Pozzi S, Alexandre P, Richardson J, Merks A, Parsons M, Kashef J, Linker C, Mayor R., Development. December 1, 2013; 140 (23): 4763-75.                                  

Engineering spatial gradients of signaling proteins using magnetic nanoparticles., Bonnemay L, Hostachy S, Hoffmann C, Gautier J, Gueroui Z., Nano Lett. November 13, 2013; 13 (11): 5147-52.

Blm10 facilitates nuclear import of proteasome core particles., Weberruss MH, Savulescu AF, Jando J, Bissinger T, Harel A, Glickman MH, Enenkel C., EMBO J. October 16, 2013; 32 (20): 2697-707.

The Prp19 complex directly functions in mitotic spindle assembly., Hofmann JC, Tegha-Dunghu J, Dräger S, Will CL, Lührmann R, Gruss OJ., PLoS One. September 3, 2013; 8 (9): e74851.          

Intranuclear DNA density affects chromosome condensation in metazoans., Hara Y, Iwabuchi M, Ohsumi K, Kimura A., Mol Biol Cell. August 1, 2013; 24 (15): 2442-53.            

The MRN-CtIP pathway is required for metaphase chromosome alignment., Rozier L, Guo Y, Peterson S, Sato M, Baer R, Gautier J, Mao Y., Mol Cell. March 28, 2013; 49 (6): 1097-107.

Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2., Petry S, Groen AC, Ishihara K, Mitchison TJ, Vale RD., Cell. February 14, 2013; 152 (4): 768-77.              

The role of NEDD1 phosphorylation by Aurora A in chromosomal microtubule nucleation and spindle function., Pinyol R, Scrofani J, Vernos I., Curr Biol. January 21, 2013; 23 (2): 143-9.                

Chromosomal gain promotes formation of a steep RanGTP gradient that drives mitosis in aneuploid cells., Hasegawa K, Ryu SJ, Kaláb P., J Cell Biol. January 21, 2013; 200 (2): 151-61.      

Mcm10 self-association is mediated by an N-terminal coiled-coil domain., Du W, Josephrajan A, Adhikary S, Bowles T, Bielinsky AK, Eichman BF., PLoS One. January 1, 2013; 8 (7): e70518.            

Chromatin-bound NLS proteins recruit membrane vesicles and nucleoporins for nuclear envelope assembly via importin-α/β., Lu Q, Lu Z, Liu Q, Guo L, Ren H, Fu J, Jiang Q, Clarke PR, Zhang C., Cell Res. November 1, 2012; 22 (11): 1562-75.

Molecular mechanism for depolarization-induced modulation of Kv channel closure., Labro AJ, Lacroix JJ, Villalba-Galea CA, Snyders DJ, Bezanilla F., J Gen Physiol. November 1, 2012; 140 (5): 481-93.                  

Mitotic spindle assembly around RCC1-coated beads in Xenopus egg extracts., Halpin D, Kalab P, Wang J, Weis K, Heald R., PLoS Biol. December 1, 2011; 9 (12): e1001225.        

RanGTP is required for meiotic spindle organization and the initiation of embryonic development in Drosophila., Cesario J, McKim KS., J Cell Sci. November 15, 2011; 124 (Pt 22): 3797-810.

Deficient induction response in a Xenopus nucleocytoplasmic hybrid., Narbonne P, Simpson DE, Gurdon JB., PLoS Biol. November 1, 2011; 9 (11): e1001197.              

Microtubule assembly in meiotic extract requires glycogen., Groen AC, Coughlin M, Mitchison TJ., Mol Biol Cell. September 1, 2011; 22 (17): 3139-51.            

Importazole, a small molecule inhibitor of the transport receptor importin-β., Soderholm JF, Bird SL, Kalab P, Sampathkumar Y, Hasegawa K, Uehara-Bingen M, Weis K, Heald R., ACS Chem Biol. July 15, 2011; 6 (7): 700-8.

Nuclear import of an intact preassembled proteasome particle., Savulescu AF, Shorer H, Kleifeld O, Cohen I, Gruber R, Glickman MH, Harel A., Mol Biol Cell. March 15, 2011; 22 (6): 880-91.                

Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK., Cross MK, Powers MA., Mol Biol Cell. March 1, 2011; 22 (5): 661-72.            

The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein., Zyłkiewicz E, Kijańska M, Choi WC, Derewenda U, Derewenda ZS, Stukenberg PT., J Cell Biol. February 7, 2011; 192 (3): 433-45.            

The role of RanGTP gradient in vertebrate oocyte maturation., Kaláb P, Solc P, Motlík J., Results Probl Cell Differ. January 1, 2011; 53 235-67.

Clathrin recruits phosphorylated TACC3 to spindle poles for bipolar spindle assembly and chromosome alignment., Fu W, Tao W, Zheng P, Fu J, Bian M, Jiang Q, Clarke PR, Zhang C., J Cell Sci. November 1, 2010; 123 (Pt 21): 3645-51.

Nuclear size is regulated by importin α and Ntf2 in Xenopus., Levy DL, Heald R., Cell. October 15, 2010; 143 (2): 288-98.          

Structure of RCC1 chromatin factor bound to the nucleosome core particle., Makde RD, England JR, Yennawar HP, Tan S., Nature. September 30, 2010; 467 (7315): 562-6.        

Expression of targeting protein for Xenopus kinesin-like protein 2 is associated with progression of human malignant astrocytoma., Li B, Qi XQ, Chen X, Huang X, Liu GY, Chen HR, Huang CG, Luo C, Lu YC., Dev Biol. September 17, 2010; 1352 200-7.

Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosis., Bompard G, Rabeharivelo G, Frank M, Cau J, Delsert C, Morin N., J Cell Biol. September 6, 2010; 190 (5): 807-22.                    

A novel mouse c-fos intronic promoter that responds to CREB and AP-1 is developmentally regulated in vivo., Coulon V, Chebli K, Cavelier P, Blanchard JM., PLoS One. June 21, 2010; 5 (6): e11235.            

Functional comparison of H1 histones in Xenopus reveals isoform-specific regulation by Cdk1 and RanGTP., Freedman BS, Heald R., Curr Biol. June 8, 2010; 20 (11): 1048-52.

Novel binding of the mitotic regulator TPX2 (target protein for Xenopus kinesin-like protein 2) to importin-alpha., Giesecke A, Stewart M., J Biol Chem. June 4, 2010; 285 (23): 17628-35.            

Microtubule assembly by the Apc protein is regulated by importin-beta--RanGTP., Dikovskaya D, Li Z, Newton IP, Davidson I, Hutchins JR, Kalab P, Clarke PR, Näthke IS., J Cell Sci. March 1, 2010; 123 (Pt 5): 736-46.

The Nup107-160 complex and gamma-TuRC regulate microtubule polymerization at kinetochores., Mishra RK, Chakraborty P, Arnaoutov A, Fontoura BM, Dasso M., Nat Cell Biol. February 1, 2010; 12 (2): 164-9.        

Transplantation of Xenopus laevis ears reveals the ability to form afferent and efferent connections with the spinal cord., Elliott KL, Fritzsch B., Int J Dev Biol. January 1, 2010; 54 (10): 1443-51.          

ISWI is a RanGTP-dependent MAP required for chromosome segregation., Yokoyama H, Rybina S, Santarella-Mellwig R, Mattaj IW, Karsenti E., J Cell Biol. December 14, 2009; 187 (6): 813-29.                    

EF hands at the N-lobe of calmodulin are required for both SK channel gating and stable SK-calmodulin interaction., Li W, Halling DB, Hall AW, Aldrich RW., J Gen Physiol. October 1, 2009; 134 (4): 281-93.            

Importin beta regulates the seeding of chromatin with initiation sites for nuclear pore assembly., Rotem A, Gruber R, Shorer H, Shaulov L, Klein E, Harel A., Mol Biol Cell. September 1, 2009; 20 (18): 4031-42.

Spindle assembly in the absence of a RanGTP gradient requires localized CPC activity., Maresca TJ, Groen AC, Gatlin JC, Ohi R, Mitchison TJ, Salmon ED., Curr Biol. July 28, 2009; 19 (14): 1210-5.

A fraction of Crm1 locates at centrosomes by its CRIME domain and regulates the centrosomal localization of pericentrin., Liu Q, Jiang Q, Zhang C., Biochem Biophys Res Commun. July 3, 2009; 384 (3): 383-8.        

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