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Summary Expression Phenotypes Gene Literature (204) GO Terms (4) Nucleotides (291) Proteins (56) Interactants (824) Wiki
XB--1001989

Papers associated with cdk2



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Cyclin E-dependent localization of MCM5 regulates centrosome duplication., Ferguson RL, Maller JL., J Cell Sci. October 1, 2008; 121 (Pt 19): 3224-32.

Selective chemical inhibition as a tool to study Cdk1 and Cdk2 functions in the cell cycle., Krasinska L, Cot E, Fisher D., Cell Cycle. June 15, 2008; 7 (12): 1702-8.

Chk1 is activated at the midblastula transition in Xenopus laevis embryos independently of DNA content and the cyclin E/Cdk2 developmental timer., Adjerid N, Wroble BN, Sible JC., Cell Cycle. April 15, 2008; 7 (8): 1112-6.

Plx1 is required for chromosomal DNA replication under stressful conditions., Trenz K, Errico A, Costanzo V., EMBO J. March 19, 2008; 27 (6): 876-85.              

Negative regulation of cell-cycle progression by RINGO/Speedy E., Dinarina A, Ruiz EJ, O'Loghlen A, Mouron S, Perez L, Nebreda AR., Biochem J. March 15, 2008; 410 (3): 535-42.

Cdk1 and Cdk2 activity levels determine the efficiency of replication origin firing in Xenopus., Krasinska L, Besnard E, Cot E, Dohet C, Méchali M, Lemaitre JM, Fisher D., EMBO J. March 5, 2008; 27 (5): 758-69.

Wee1 kinase alters cyclin E/Cdk2 and promotes apoptosis during the early embryonic development of Xenopus laevis., Wroble BN, Finkielstein CV, Sible JC., BMC Dev Biol. October 25, 2007; 7 119.          

Anti-breast cancer activity of LFM-A13, a potent inhibitor of Polo-like kinase (PLK)., Uckun FM, Dibirdik I, Qazi S, Vassilev A, Ma H, Mao C, Benyumov A, Emami KH., Bioorg Med Chem. January 15, 2007; 15 (2): 800-14.

Nucleocytoplasmic shuttling of bovine papillomavirus E1 helicase downregulates viral DNA replication in S phase., Hsu CY, Mechali F, Bonne-Andrea C., J Virol. January 1, 2007; 81 (1): 384-94.

Metaphase arrest by cyclin E-Cdk2 requires the spindle-checkpoint kinase Mps1., Grimison B, Liu J, Lewellyn AL, Maller JL., Curr Biol. October 10, 2006; 16 (19): 1968-73.

Cyclin A1/Cdk2 is sufficient but not required for the induction of apoptosis in early Xenopus laevis embryos., Carter AD, Wroble BN, Sible JC., Cell Cycle. October 1, 2006; 5 (19): 2230-6.

Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation., Gutierrez GJ, Vögtlin A, Castro A, Ferby I, Salvagiotto G, Ronai Z, Lorca T, Nebreda AR., Nat Cell Biol. October 1, 2006; 8 (10): 1084-94.

Mechanistic studies of the mitotic activation of Mos., Yue J, Ferrell JE., Mol Cell Biol. July 1, 2006; 26 (14): 5300-9.              

CDK activation by non-cyclin proteins., Nebreda AR., Curr Opin Cell Biol. April 1, 2006; 18 (2): 192-8.

Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint., Petersen P, Chou DM, You Z, Hunter T, Walter JC, Walter G., Mol Cell Biol. March 1, 2006; 26 (5): 1997-2011.

Ubiquitination of cyclin-dependent kinase inhibitor, Xic1, is mediated by the Xenopus F-box protein xSkp2., Lin HR, Chuang LC, Boix-Perales H, Philpott A, Yew PR., Cell Cycle. February 1, 2006; 5 (3): 304-14.

ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha., Dong Z, Tomkinson AE., Nucleic Acids Res. January 1, 2006; 34 (20): 5721-279.              

Proliferating cell nuclear antigen recruits cyclin-dependent kinase inhibitor Xic1 to DNA and couples its proteolysis to DNA polymerase switching., Chuang LC, Yew PR., J Biol Chem. October 21, 2005; 280 (42): 35299-309.

The C-terminal domain of the Xenopus cyclin-dependent kinase inhibitor, p27Xic1, is both necessary and sufficient for phosphorylation-independent proteolysis., Chuang LC, Zhu XN, Herrera CR, Tseng HM, Pfleger CM, Block K, Yew PR., J Biol Chem. October 21, 2005; 280 (42): 35290-8.

Biochemical characterization of Cdk2-Speedy/Ringo A2., Cheng A, Gerry S, Kaldis P, Solomon MJ., BMC Biochem. September 28, 2005; 6 19.              

A novel Cdk2 interactor is phosphorylated by Cdc7 and associates with components of the replication complexes., Grishina I, Lattes B., Cell Cycle. August 1, 2005; 4 (8): 1120-6.

Over-expression of Aurora-A targets cytoplasmic polyadenylation element binding protein and promotes mRNA polyadenylation of Cdk1 and cyclin B1., Sasayama T, Marumoto T, Kunitoku N, Zhang D, Tamaki N, Kohmura E, Saya H, Hirota T., Genes Cells. July 1, 2005; 10 (7): 627-38.          

Characterization of a new family of cyclin-dependent kinase activators., Dinarina A, Perez LH, Davila A, Schwab M, Hunt T, Nebreda AR., Biochem J. March 1, 2005; 386 (Pt 2): 349-55.

Cdk2 activity is essential for the first to second meiosis transition in porcine oocytes., Sugiura K, Naito K, Tojo H., J Reprod Dev. February 1, 2005; 51 (1): 143-9.

ATM and ATR check in on origins: a dynamic model for origin selection and activation., Shechter D, Gautier J., Cell Cycle. February 1, 2005; 4 (2): 235-8.

Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins., Cheng A, Xiong W, Ferrell JE, Solomon MJ., Cell Cycle. January 1, 2005; 4 (1): 155-65.

Methods for preparation of proteins and protein complexes that regulate the eukaryotic cell cycle for structural studies., Welburn J, Endicott J., Methods Mol Biol. January 1, 2005; 296 219-35.

Identification of Xenopus cyclin-dependent kinase inhibitors, p16Xic2 and p17Xic3., Daniels M, Dhokia V, Richard-Parpaillon L, Ohnuma S., Gene. November 10, 2004; 342 (1): 41-7.                

Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex., Takahashi TS, Yiu P, Chou MF, Gygi S, Walter JC., Nat Cell Biol. October 1, 2004; 6 (10): 991-6.

Chk1, but not Chk2, inhibits Cdc25 phosphatases by a novel common mechanism., Uto K, Inoue D, Shimuta K, Nakajo N, Sagata N., EMBO J. August 18, 2004; 23 (16): 3386-96.

ATR and ATM regulate the timing of DNA replication origin firing., Shechter D, Costanzo V, Gautier J., Nat Cell Biol. July 1, 2004; 6 (7): 648-55.

G1/S phase cyclin-dependent kinase overexpression perturbs early development and delays tissue-specific differentiation in Xenopus., Richard-Parpaillon L, Cosgrove RA, Devine C, Vernon AE, Philpott A., Development. June 1, 2004; 131 (11): 2577-86.              

Cyclin A/Cdk2 complexes regulate activation of Cdk1 and Cdc25 phosphatases in human cells., Mitra J, Enders GH., Oncogene. April 22, 2004; 23 (19): 3361-7.

Inhibition of the cell cycle is required for convergent extension of the paraxial mesoderm during Xenopus neurulation., Leise WF, Mueller PR., Development. April 1, 2004; 131 (8): 1703-15.              

When the checkpoints have gone: insights into Cdc25 functional activation., Margolis SS, Kornbluth S., Cell Cycle. April 1, 2004; 3 (4): 425-8.

Cdk1: unsung hero of S phase?, Pacek M, Prokhorova TA, Walter JC., Cell Cycle. April 1, 2004; 3 (4): 401-3.

DNA replication of mitotic chromatin in Xenopus egg extracts., Prokhorova TA, Mowrer K, Gilbert CH, Walter JC., Proc Natl Acad Sci U S A. November 11, 2003; 100 (23): 13241-6.

PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation., Margolis SS, Walsh S, Weiser DC, Yoshida M, Shenolikar S, Kornbluth S., EMBO J. November 3, 2003; 22 (21): 5734-45.

Spy1 interacts with p27Kip1 to allow G1/S progression., Porter LA, Kong-Beltran M, Donoghue DJ., Mol Biol Cell. September 1, 2003; 14 (9): 3664-74.

A kinetic model of the cyclin E/Cdk2 developmental timer in Xenopus laevis embryos., Ciliberto A, Petrus MJ, Tyson JJ, Sible JC., Biophys Chem. July 1, 2003; 104 (3): 573-89.

The developmental expression of cell cycle regulators in Xenopus laevis., Vernon AE, Philpott A., Gene Expr Patterns. May 1, 2003; 3 (2): 179-92.                  

Expression of cell-cycle regulators during Xenopus oogenesis., Furuno N, Kawasaki A, Sagata N., Gene Expr Patterns. May 1, 2003; 3 (2): 165-8.        

A role for Ran-GTP and Crm1 in blocking re-replication., Yamaguchi R, Newport J., Cell. April 4, 2003; 113 (1): 115-25.

Cyclin-dependent kinases and S phase control in mammalian cells., Woo RA, Poon RY., Cell Cycle. January 1, 2003; 2 (4): 316-24.

Xrx1 controls proliferation and multipotency of retinal progenitors., Casarosa S, Amato MA, Andreazzoli M, Gestri G, Barsacchi G, Cremisi F., Mol Cell Neurosci. January 1, 2003; 22 (1): 25-36.

Identification of the nuclear localization signal in Xenopus cyclin E and analysis of its role in replication and mitosis., Moore JD, Kornbluth S, Hunt T., Mol Biol Cell. December 1, 2002; 13 (12): 4388-400.

Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex., Chou DM, Petersen P, Walter JC, Walter G., J Biol Chem. October 25, 2002; 277 (43): 40520-7.

A role for G1/S cyclin-dependent protein kinases in the apoptotic response to ionizing radiation., Finkielstein CV, Chen LG, Maller JL., J Biol Chem. October 11, 2002; 277 (41): 38476-85.

MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts., Edwards MC, Tutter AV, Cvetic C, Gilbert CH, Prokhorova TA, Walter JC., J Biol Chem. September 6, 2002; 277 (36): 33049-57.

Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition., Shimuta K, Nakajo N, Uto K, Hayano Y, Okazaki K, Sagata N., EMBO J. July 15, 2002; 21 (14): 3694-703.

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