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Summary Expression Phenotypes Gene Literature (172) GO Terms (8) Nucleotides (126) Proteins (59) Interactants (895) Wiki
XB--487097

Papers associated with gsk3b



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Inhibition of heart formation by lithium is an indirect result of the disruption of tissue organization within the embryo., Martin LK, Bratoeva M, Mezentseva NV, Bernanke JM, Remond MC, Ramsdell AF, Eisenberg CA, Eisenberg LM., Dev Growth Differ. February 1, 2012; 54 (2): 153-66.                

Cortical rotation and messenger RNA localization in Xenopus axis formation., Houston DW., Wiley Interdiscip Rev Dev Biol. January 1, 2012; 1 (3): 371-88.        

Canonical WNT signaling enhances stem cell expression in the developing heart without a corresponding inhibition of cardiogenic differentiation., Martin LK, Mezentseva NV, Bratoeva M, Ramsdell AF, Eisenberg CA, Eisenberg LM., Stem Cells Dev. November 1, 2011; 20 (11): 1973-83.

A novel mechanism for the transcriptional regulation of Wnt signaling in development., Vacik T, Stubbs JL, Lemke G., Genes Dev. September 1, 2011; 25 (17): 1783-95.      

Notch destabilises maternal beta-catenin and restricts dorsal-anterior development in Xenopus., Acosta H, López SL, Revinski DR, Carrasco AE., Development. June 1, 2011; 138 (12): 2567-79.                          

PKB/SGK-resistant GSK3 enhances phosphaturia and calciuria., Föller M, Kempe DS, Boini KM, Pathare G, Siraskar B, Capuano P, Alesutan I, Sopjani M, Stange G, Mohebbi N, Bhandaru M, Ackermann TF, Judenhofer MS, Pichler BJ, Biber J, Wagner CA, Lang F., J Am Soc Nephrol. May 1, 2011; 22 (5): 873-80.

Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2., Hikasa H, Sokol SY., J Biol Chem. April 8, 2011; 286 (14): 12093-100.

Network based transcription factor analysis of regenerating axolotl limbs., Jhamb D, Rao N, Milner DJ, Song F, Cameron JA, Stocum DL, Palakal MJ., BMC Bioinformatics. March 18, 2011; 12 80.              

Different requirement for Wnt/β-catenin signaling in limb regeneration of larval and adult Xenopus., Yokoyama H, Maruoka T, Ochi H, Aruga A, Ohgo S, Ogino H, Tamura K, Tamura K., PLoS One. January 1, 2011; 6 (7): e21721.                

Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes., Taelman VF, Dobrowolski R, Plouhinec JL, Fuentealba LC, Vorwald PP, Gumper I, Sabatini DD, De Robertis EM., Cell. December 23, 2010; 143 (7): 1136-48.        

A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription., Ewan K, Pajak B, Stubbs M, Todd H, Barbeau O, Quevedo C, Botfield H, Young R, Ruddle R, Samuel L, Battersby A, Raynaud F, Allen N, Wilson S, Latinkic B, Workman P, McDonald E, Blagg J, Aherne W, Dale T., Cancer Res. July 15, 2010; 70 (14): 5963-73.

Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity., Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E., Sci Signal. May 11, 2010; 3 (121): ra37.

Systematic discovery of nonobvious human disease models through orthologous phenotypes., McGary KL, Park TJ, Woods JO, Cha HJ, Wallingford JB, Marcotte EM., Proc Natl Acad Sci U S A. April 6, 2010; 107 (14): 6544-9.                                    

p63 antagonizes Wnt-induced transcription., Drewelus I, Göpfert C, Hippel C, Dickmanns A, Damianitsch K, Pieler T, Dobbelstein M., Cell Cycle. February 1, 2010; 9 (3): 580-87.

Stimulation of electrogenic glucose transport by glycogen synthase kinase 3., Rexhepaj R, Dërmaku-Sopjani M, Gehring EM, Sopjani M, Kempe DS, Föller M, Lang F., Cell Physiol Biochem. January 1, 2010; 26 (4-5): 641-6.

Evidence that fold-change, and not absolute level, of beta-catenin dictates Wnt signaling., Goentoro L, Kirschner MW., Mol Cell. December 11, 2009; 36 (5): 872-84.                                      

Threonine 393 of beta-catenin regulates interaction with Axin., Wu H, Symes K, Seldin DC, Dominguez I., J Cell Biochem. September 1, 2009; 108 (1): 52-63.

Early requirement of Hyaluronan for tail regeneration in Xenopus tadpoles., Contreras EG, Gaete M, Sánchez N, Carrasco H, Larraín J., Development. September 1, 2009; 136 (17): 2987-96.                    

Mad is required for wingless signaling in wing development and segment patterning in Drosophila., Eivers E, Fuentealba LC, Sander V, Clemens JC, Hartnett L, De Robertis EM., PLoS One. August 6, 2009; 4 (8): e6543.                    

Wnt/beta-catenin signaling: components, mechanisms, and diseases., MacDonald BT, Tamai K, He X., Dev Cell. July 1, 2009; 17 (1): 9-26.          

Identification of targets of the Wnt pathway destruction complex in addition to beta-catenin., Kim NG, Xu C, Gumbiner BM., Proc Natl Acad Sci U S A. March 31, 2009; 106 (13): 5165-70.

Differential requirements of BMP and Wnt signalling during gastrulation and neurulation define two steps in neural crest induction., Steventon B, Araya C, Linker C, Kuriyama S, Mayor R., Development. March 1, 2009; 136 (5): 771-9.        

Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6., Wu G, Huang H, Garcia Abreu J, He X., PLoS One. January 1, 2009; 4 (3): e4926.              

Integrating positional information at the level of Smad1/5/8., Eivers E, Fuentealba LC, De Robertis EM., Curr Opin Genet Dev. August 1, 2008; 18 (4): 304-10.

Antibody microarray analyses of signal transduction protein expression and phosphorylation during porcine oocyte maturation., Pelech S, Jelinkova L, Susor A, Zhang H, Shi X, Pavlok A, Kubelka M, Kovarova H., J Proteome Res. July 1, 2008; 7 (7): 2860-71.

Possible involvement of phosphatidylinositol 3-kinase, but not protein kinase B or glycogen synthase kinase 3beta, in progesterone-induced oocyte maturation in the Japanese brown frog, Rana japonica., Ota R, Suwa K, Kotani T, Mita K, Yamashita M., Zoolog Sci. July 1, 2008; 25 (7): 773-81.

LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin., Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E, Lee E., Proc Natl Acad Sci U S A. June 10, 2008; 105 (23): 8032-7.        

Silencing of Smed-betacatenin1 generates radial-like hypercephalized planarians., Iglesias M, Gomez-Skarmeta JL, Saló E, Adell T., Development. April 1, 2008; 135 (7): 1215-21.  

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions., Zeng X, Huang H, Tamai K, Zhang X, Harada Y, Yokota C, Almeida K, Wang J, Doble B, Woodgett J, Wynshaw-Boris A, Hsieh JC, He X., Development. January 1, 2008; 135 (2): 367-75.

Unexpected activities of Smad7 in Xenopus mesodermal and neural induction., de Almeida I, Rolo A, Batut J, Hill C, Stern CD, Linker C., Mech Dev. January 1, 2008; 125 (5-6): 421-31.              

Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling., Piao S, Lee SH, Kim H, Yum S, Stamos JL, Xu Y, Xu Y, Lee SJ, Lee J, Lee J, Oh S, Han JK, Park BJ, Weis WI, Ha NC., PLoS One. January 1, 2008; 3 (12): e4046.          

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal., Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM, De Robertis EM., Cell. November 30, 2007; 131 (5): 980-93.      

Phosphorylation and functions of inhibitor-2 family of proteins., Li M, Satinover DL, Brautigan DL., Biochemistry. March 6, 2007; 46 (9): 2380-9.

Nuclear localization signals of the E-cadherin transcriptional repressor Snail., Ko H, Kim HS, Kim NH, Lee SH, Kim KH, Hong SH, Yook JI., Cells Tissues Organs. January 1, 2007; 185 (1-3): 66-72.

Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos., Nagano T, Takehara S, Takahashi M, Aizawa S, Yamamoto A., Development. December 1, 2006; 133 (23): 4643-54.                  

FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A., Hagen T, Cross DA, Culbert AA, West A, Frame S, Morrice N, Reith AD., J Biol Chem. November 17, 2006; 281 (46): 35021-9.

Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos., Liao G, Tao Q, Tao Q, Kofron M, Chen JS, Schloemer A, Davis RJ, Hsieh JC, Wylie C, Heasman J, Kuan CY., Proc Natl Acad Sci U S A. October 31, 2006; 103 (44): 16313-8.                    

The endocrine-disrupting compound, nonylphenol, inhibits neurotrophin-dependent neurite outgrowth., Bevan CL, Porter DM, Schumann CR, Bryleva EY, Hendershot TJ, Liu H, Howard MJ, Henderson LP., Endocrinology. September 1, 2006; 147 (9): 4192-204.

[Molecular mechanism of axon guidance]., Goshima Y., Nihon Shinkei Seishin Yakurigaku Zasshi. June 1, 2006; 26 (3): 135-40.

The zic1 gene is an activator of Wnt signaling., Merzdorf CS, Sive HL., Int J Dev Biol. January 1, 2006; 50 (7): 611-7.              

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation., Zeng X, Tamai K, Doble B, Li S, Huang H, Habas R, Okamura H, Woodgett J, He X., Nature. December 8, 2005; 438 (7069): 873-7.

Early steps in neural crest specification., Barembaum M, Bronner-Fraser M., Semin Cell Dev Biol. December 1, 2005; 16 (6): 642-6.      

beta-Catenin controls cell sorting at the notochord-somite boundary independently of cadherin-mediated adhesion., Reintsch WE, Habring-Mueller A, Wang RW, Schohl A, Fagotto F., J Cell Biol. August 15, 2005; 170 (4): 675-86.              

Re-evaluating the role of Frat in Wnt-signal transduction., van Amerongen R, Berns A., Cell Cycle. August 1, 2005; 4 (8): 1065-72.

Wnt-dependent regulation of the E-cadherin repressor snail., Yook JI, Li XY, Ota I, Fearon ER, Weiss SJ., J Biol Chem. March 25, 2005; 280 (12): 11740-8.

Frat is dispensable for canonical Wnt signaling in mammals., van Amerongen R, Nawijn M, Franca-Koh J, Zevenhoven J, van der Gulden H, Jonkers J, Berns A., Genes Dev. February 15, 2005; 19 (4): 425-30.

Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction., Monsoro-Burq AH, Wang E, Harland R., Dev Cell. February 1, 2005; 8 (2): 167-78.            

Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex., Foley AC, Mercola M., Genes Dev. February 1, 2005; 19 (3): 387-96.            

PR72, a novel regulator of Wnt signaling required for Naked cuticle function., Creyghton MP, Roël G, Eichhorn PJ, Hijmans EM, Maurer I, Destrée O, Bernards R., Genes Dev. February 1, 2005; 19 (3): 376-86.            

Cross-regulation of Wnt signaling and cell adhesion., Schambony A, Kunz M, Gradl D., Differentiation. September 1, 2004; 72 (7): 307-18.

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