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Summary Expression Phenotypes Gene Literature (128) GO Terms (15) Nucleotides (130) Proteins (52) Interactants (858) Wiki
XB--487158

Papers associated with hhex



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The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification., Spagnoli FM, Brivanlou AH., Dev Biol. April 15, 2006; 292 (2): 442-56.                      

Conserved roles for Oct4 homologues in maintaining multipotency during early vertebrate development., Morrison GM, Brickman JM., Development. May 1, 2006; 133 (10): 2011-22.                

Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue., Afelik S, Chen Y, Pieler T., Genes Dev. June 1, 2006; 20 (11): 1441-6.                        

Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal., Zamparini AL, Watts T, Gardner CE, Tomlinson SR, Johnston GI, Brickman JM., Development. September 1, 2006; 133 (18): 3709-22.                                    

A role for GATA factors in Xenopus gastrulation movements., Fletcher G, Jones GE, Patient R, Snape A., Mech Dev. October 1, 2006; 123 (10): 730-45.    

Embryonic heart induction., Foley AC, Gupta RW, Guzzo RM, Korol O, Mercola M., Ann N Y Acad Sci. October 1, 2006; 1080 85-96.

Multiple functions of Cerberus cooperate to induce heart downstream of Nodal., Foley AC, Korol O, Timmer AM, Mercola M., Dev Biol. March 1, 2007; 303 (1): 57-65.        

Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas., Jarikji ZH, Vanamala S, Beck CW, Wright CV, Leach SD, Horb ME., Dev Biol. April 15, 2007; 304 (2): 786-99.                

Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development., McLin VA, Rankin SA, Zorn AM., Development. June 1, 2007; 134 (12): 2207-17.            

Enzymatic suppression of the membrane conductance associated with the glutamine transporter SNAT3 expressed in Xenopus oocytes by carbonic anhydrase II., Weise A, Becker HM, Deitmer JW., J Gen Physiol. August 1, 2007; 130 (2): 203-15.              

Retinoic acid-mediated patterning of the pre-pancreatic endoderm in Xenopus operates via direct and indirect mechanisms., Pan FC, Chen Y, Chen Y, Bayha E, Pieler T., Mech Dev. August 1, 2007; 124 (7-8): 518-31.      

A role of D domain-related proteins in differentiation and migration of embryonic cells in Xenopus laevis., Shibata T, Takahashi Y, Tasaki J, Saito Y, Izutsu Y, Maéno M., Mech Dev. January 1, 2008; 125 (3-4): 284-98.                            

The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm., Spagnoli FM, Brivanlou AH., Development. February 1, 2008; 135 (3): 451-61.                                                    

A crucial role of a high mobility group protein HMGA2 in cardiogenesis., Monzen K, Ito Y, Naito AT, Kasai H, Hiroi Y, Hayashi D, Shiojima I, Yamazaki T, Miyazono K, Asashima M, Nagai R, Komuro I., Nat Cell Biol. May 1, 2008; 10 (5): 567-74.                  

XHAPLN3 plays a key role in cardiogenesis by maintaining the hyaluronan matrix around heart anlage., Ito Y, Seno S, Nakamura H, Fukui A, Asashima M., Dev Biol. July 1, 2008; 319 (1): 34-45.                          

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis., Zhu W, Shiojima I, Ito Y, Li Z, Ikeda H, Yoshida M, Naito AT, Nishi J, Ueno H, Umezawa A, Minamino T, Nagai T, Kikuchi A, Asashima M, Komuro I., Nature. July 17, 2008; 454 (7202): 345-9.                        

GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos., Haworth KE, Kotecha S, Mohun TJ, Latinkic BV., BMC Dev Biol. July 28, 2008; 8 74.                        

Bmp signaling is necessary and sufficient for ventrolateral endoderm specification in Xenopus., Wills A, Dickinson K, Khokha M, Baker JC., Dev Dyn. August 1, 2008; 237 (8): 2177-86.      

Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling., Li Y, Rankin SA, Rankin SA, Sinner D, Kenny AP, Krieg PA, Zorn AM., Genes Dev. November 1, 2008; 22 (21): 3050-63.                        

The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds., Jarikji Z, Horb LD, Shariff F, Mandato CA, Cho KW, Horb ME., Development. June 1, 2009; 136 (11): 1791-800.                  

Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity., Tao H, Suzuki M, Kiyonari H, Abe T, Sasaoka T, Ueno N., Proc Natl Acad Sci U S A. August 25, 2009; 106 (34): 14426-31.      

Xenopus insm1 is essential for gastrointestinal and pancreatic endocrine cell development., Horb LD, Jarkji ZH, Horb ME., Dev Dyn. October 1, 2009; 238 (10): 2505-10.                

Early activation of FGF and nodal pathways mediates cardiac specification independently of Wnt/beta-catenin signaling., Samuel LJ, Latinkić BV., PLoS One. October 28, 2009; 4 (10): e7650.                

Identification and expression of ventrally associated leucine-zipper (VAL) in Xenopus embryo., Saito Y, Takahashi Y, Izutsu Y, Maeno M., Int J Dev Biol. January 1, 2010; 54 (1): 203-8.                

Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells., Wen L, Yang Y, Yang Y, Wang Y, Xu A, Wu D, Chen Y, Chen Y., Dev Dyn. August 1, 2010; 239 (8): 2198-207.                                          

Wnt/beta-catenin signaling is involved in the induction and maintenance of primitive hematopoiesis in the vertebrate embryo., Tran HT, Sekkali B, Van Imschoot G, Janssens S, Vleminckx K, Vleminckx K., Proc Natl Acad Sci U S A. September 14, 2010; 107 (37): 16160-5.                                                

BrunoL1 regulates endoderm proliferation through translational enhancement of cyclin A2 mRNA., Horb LD, Horb ME., Dev Biol. September 15, 2010; 345 (2): 156-69.                

Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo., Lim JW, Hummert P, Mills JC, Kroll KL., Development. January 1, 2011; 138 (1): 33-44.                    

Retinoic acid is a key regulatory switch determining the difference between lung and thyroid fates in Xenopus laevis., Wang JH, Deimling SJ, D'Alessandro NE, Zhao L, Possmayer F, Drysdale TA., BMC Dev Biol. January 26, 2011; 11 75.                            

Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes., Pearl EJ, Jarikji Z, Horb ME., Dev Biol. March 1, 2011; 351 (1): 135-45.                    

A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer., Rankin SA, Rankin SA, Kormish J, Kofron M, Jegga A, Zorn AM., Dev Biol. March 15, 2011; 351 (2): 297-310.                            

Ventx factors function as Nanog-like guardians of developmental potential in Xenopus., Scerbo P, Girardot F, Vivien C, Markov GV, Luxardi G, Demeneix B, Kodjabachian L, Coen L., PLoS One. January 1, 2012; 7 (5): e36855.              

Identification of new agonists and antagonists of the insect odorant receptor co-receptor subunit., Chen S, Luetje CW., PLoS One. January 1, 2012; 7 (5): e36784.          

Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells., Oropeza D, Horb M., Genesis. March 1, 2012; 50 (3): 271-85.                        

Xenopus staufen2 is required for anterior endodermal organ formation., Bilogan CK, Horb ME., Genesis. March 1, 2012; 50 (3): 251-9.                      

Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos., Zhao H, Han D, Dawid IB, Pieler T, Chen Y, Chen Y., Proc Natl Acad Sci U S A. May 29, 2012; 109 (22): 8594-9.                              

Sizzled-tolloid interactions maintain foregut progenitors by regulating fibronectin-dependent BMP signaling., Kenny AP, Rankin SA, Rankin SA, Allbee AW, Prewitt AR, Zhang Z, Tabangin ME, Shifley ET, Louza MP, Zorn AM., Dev Cell. August 14, 2012; 23 (2): 292-304.                                

Prolonged FGF signaling is necessary for lung and liver induction in Xenopus., Shifley ET, Kenny AP, Rankin SA, Rankin SA, Zorn AM., BMC Dev Biol. September 18, 2012; 12 27.                      

β-hexosaminidase from Xenopus laevis eggs and oocytes: from gene to immunochemical characterization., Morales ES, Krapf D, Botta PE, Cabada MO, Arranz SE., J Cell Biochem. December 1, 2012; 113 (12): 3709-20.

Optimal histone H3 to linker histone H1 chromatin ratio is vital for mesodermal competence in Xenopus., Lim CY, Reversade B, Knowles BB, Solter D., Development. February 1, 2013; 140 (4): 853-60.                                              

Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut., Dush MK, Nascone-Yoder NM., Development. April 1, 2013; 140 (7): 1457-66.                      

Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells., Zhang Z, Rankin SA, Zorn AM., Dev Biol. June 1, 2013; 378 (1): 1-12.                              

VEGFA-dependent and -independent pathways synergise to drive Scl expression and initiate programming of the blood stem cell lineage in Xenopus., Ciau-Uitz A, Pinheiro P, Kirmizitas A, Zuo J, Patient R., Development. June 1, 2013; 140 (12): 2632-42.                                                                                                                            

TBX3 Directs Cell-Fate Decision toward Mesendoderm., Weidgang CE, Russell R, Tata PR, Kühl SJ, Illing A, Müller M, Lin Q, Brunner C, Boeckers TM, Bauer K, Kartikasari AE, Guo Y, Radenz M, Bernemann C, Weiß M, Seufferlein T, Zenke M, Iacovino M, Kyba M, Schöler HR, Kühl M, Liebau S, Kleger A., Stem Cell Reports. August 29, 2013; 1 (3): 248-65.                

Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence., Rodríguez-Seguel E, Mah N, Naumann H, Pongrac IM, Cerdá-Esteban N, Fontaine JF, Wang Y, Chen W, Andrade-Navarro MA, Spagnoli FM., Genes Dev. September 1, 2013; 27 (17): 1932-46.    

Discovery of novel ligands for mouse olfactory receptor MOR42-3 using an in silico screening approach and in vitro validation., Bavan S, Sherman B, Luetje CW, Abaffy T., PLoS One. January 1, 2014; 9 (3): e92064.            

Inference of the Xenopus tropicalis embryonic regulatory network and spatial gene expression patterns., Zheng Z, Christley S, Chiu WT, Blitz IL, Xie X, Cho KW, Nie Q., BMC Syst Biol. January 8, 2014; 8 3.                  

Efficient RNA/Cas9-mediated genome editing in Xenopus tropicalis., Guo X, Zhang T, Hu Z, Zhang Y, Zhang Y, Shi Z, Wang Q, Cui Y, Wang F, Zhao H, Chen Y, Chen Y., Development. February 1, 2014; 141 (3): 707-14.              

Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements., Rutledge CE, Lau HT, Mangan H, Hardy LL, Sunnotel O, Guo F, MacNicol AM, Walsh CP, Lees-Murdock DJ., PLoS One. February 19, 2014; 9 (2): e88385.        

Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells., Liu Y, Kaneda R, Leja TW, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz RJ, Barahona M, Schneider MD., Stem Cells. June 1, 2014; 32 (6): 1515-26.              

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