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Summary Expression Phenotypes Gene Literature (455) GO Terms (15) Nucleotides (103) Proteins (33) Interactants (2052) Wiki
XB--488038

Papers associated with shh



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WDR5 regulates left-right patterning via chromatin-dependent and -independent functions., Kulkarni SS, Khokha MK., Development. November 28, 2018; 145 (23):                 

Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development., Steimle JD, Rankin SA, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK, Kyba M, Jensen B, Zorn AM, Conlon FL, Moskowitz IP., Proc Natl Acad Sci U S A. November 6, 2018; 115 (45): E10615-E10624.                                  

The cytoskeletal protein Zyxin interacts with the zinc-finger transcription factor Zic1 and plays the role of a scaffold for Gli1 and Zic1 interactions during early development of Xenopus laevis., Martynova NY, Parshina EA, Ermolina LV, Zaraisky AG., Biochem Biophys Res Commun. September 26, 2018; 504 (1): 251-256.

Structural Basis of Smoothened Activation in Hedgehog Signaling., Huang P, Zheng S, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse AC, Salic A., Cell. July 12, 2018; 174 (2): 312-324.e16.

Coordinated d-cyclin/Foxd1 activation drives mitogenic activity of the Sonic Hedgehog signaling pathway., Fink DM, Sun MR, Heyne GW, Everson JL, Chung HM, Park S, Sheets MD, Lipinski RJ., Cell Signal. April 1, 2018; 44 1-9.

Divergent axial morphogenesis and early shh expression in vertebrate prospective floor plate., Kremnyov S, Henningfeld K, Viebahn C, Tsikolia N., Evodevo. January 31, 2018; 9 4.                    

Hyperinnervation improves Xenopus laevis limb regeneration., Mitogawa K, Makanae A, Satoh A., Dev Biol. January 15, 2018; 433 (2): 276-286.                    

Musashi and Plasticity of Xenopus and Axolotl Spinal Cord Ependymal Cells., Chernoff EAG, Sato K, Salfity HVN, Sarria DA, Belecky-Adams T., Front Cell Neurosci. January 1, 2018; 12 45.                          

Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways., Sigg MA, Menchen T, Lee C, Lee C, Johnson J, Jungnickel MK, Choksi SP, Garcia G, Busengdal H, Dougherty GW, Pennekamp P, Werner C, Rentzsch F, Florman HM, Krogan N, Wallingford JB, Omran H, Reiter JF., Dev Cell. December 18, 2017; 43 (6): 744-762.e11.      

Sonic hedgehog antagonists reduce size and alter patterning of the frog inner ear., Zarei S, Zarei K, Fritzsch B, Elliott KL., Dev Neurobiol. December 1, 2017; 77 (12): 1385-1400.                

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

SHH signaling directed by two oral epithelium-specific enhancers controls tooth and oral development., Sagai T, Amano T, Maeno A, Kiyonari H, Seo H, Cho SW, Shiroishi T., Sci Rep. October 11, 2017; 7 (1): 13004.          

hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus., Prager A, Hagenlocher C, Ott T, Schambony A, Feistel K., Dev Biol. October 1, 2017; 430 (1): 188-201.                      

Mouth development., Chen J, Jacox LA, Saldanha F, Sive H., Wiley Interdiscip Rev Dev Biol. September 1, 2017; 6 (5):               

Folate-dependent methylation of septins governs ciliogenesis during neural tube closure., Toriyama M, Toriyama M, Wallingford JB, Finnell RH., FASEB J. August 1, 2017; 31 (8): 3622-3635.                    

Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing., Popov IK, Kwon T, Crossman DK, Crowley MR, Wallingford JB, Chang C., Dev Biol. June 15, 2017; 426 (2): 429-441.                    

High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  

Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis., Pitcairn E, Harris H, Epiney J, Pai VP, Lemire JM, Ye B, Shi NQ, Levin M, McLaughlin KA., Commun Integr Biol. May 10, 2017; 10 (3): e1309488.                            

The Sox transcriptional factors: Functions during intestinal development in vertebrates., Fu L, Shi YB., Semin Cell Dev Biol. March 1, 2017; 63 58-67.        

A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse., Ulmer B, Tingler M, Kurz S, Maerker M, Andre P, Mönch D, Campione M, Deißler K, Lewandoski M, Thumberger T, Schweickert A, Fainsod A, Steinbeißer H, Blum M., Sci Rep. February 21, 2017; 7 43010.                  

Regulation of TRPP3 Channel Function by N-terminal Domain Palmitoylation and Phosphorylation., Zheng W, Yang J, Beauchamp E, Cai R, Hussein S, Hofmann L, Li Q, Flockerzi V, Berthiaume LG, Tang J, Chen XZ., J Biol Chem. December 2, 2016; 291 (49): 25678-25691.

Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling., Jin Z, Schwend T, Fu J, Bao Z, Liang J, Zhao H, Mei W, Yang J., Development. November 1, 2016; 143 (21): 3944-3955.                        

Genome evolution in the allotetraploid frog Xenopus laevis., Session AM, Uno Y, Kwon T, Chapman JA, Toyoda A, Takahashi S, Fukui A, Hikosaka A, Suzuki A, Kondo M, van Heeringen SJ, Quigley I, Heinz S, Ogino H, Ochi H, Hellsten U, Lyons JB, Simakov O, Putnam N, Stites J, Kuroki Y, Tanaka T, Michiue T, Watanabe M, Bogdanovic O, Lister R, Georgiou G, Paranjpe SS, van Kruijsbergen I, Shu S, Carlson J, Kinoshita T, Ohta Y, Mawaribuchi S, Jenkins J, Grimwood J, Schmutz J, Mitros T, Mozaffari SV, Suzuki Y, Haramoto Y, Yamamoto TS, Takagi C, Heald R, Miller K, Haudenschild C, Kitzman J, Nakayama T, Izutsu Y, Robert J, Fortriede J, Burns K, Lotay V, Karimi K, Yasuoka Y, Dichmann DS, Flajnik MF, Houston DW, Shendure J, DuPasquier L, Vize PD, Zorn AM, Ito M, Marcotte EM, Wallingford JB, Ito Y, Asashima M, Ueno N, Matsuda Y, Veenstra GJ, Fujiyama A, Harland RM, Taira M, Rokhsar DS., Nature. October 20, 2016; 538 (7625): 336-343.                              

An Evolutionarily Conserved Network Mediates Development of the zona limitans intrathalamica, a Sonic Hedgehog-Secreting Caudal Forebrain Signaling Center., Sena E, Feistel K, Durand BC., J Dev Biol. October 20, 2016; 4 (4):       

Hedgehog-dependent E3-ligase Midline1 regulates ubiquitin-mediated proteasomal degradation of Pax6 during visual system development., Pfirrmann T, Jandt E, Ranft S, Lokapally A, Neuhaus H, Perron M, Hollemann T., Proc Natl Acad Sci U S A. September 6, 2016; 113 (36): 10103-8.                    

IFT46 plays crucial roles in craniofacial and cilia development., Park I, Lee HK, Kim C, Ismail T, Kim YK, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Park MJ, Choi SC, Lee HS., Biochem Biophys Res Commun. August 26, 2016; 477 (3): 419-25.            

Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling., Huang P, Nedelcu D, Watanabe M, Jao C, Kim Y, Liu J, Salic A., Cell. August 25, 2016; 166 (5): 1176-1187.e14.

Insight from Frogs: Sonic Hedgehog Gene Expression and a Re-evaluation of the Vertebrate Odontogenic Band., Grieco TM, Hlusko LJ., Anat Rec (Hoboken). August 1, 2016; 299 (8): 1099-109.

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification., Rankin SA, Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM., Cell Rep. June 28, 2016; 16 (1): 66-78.                                              

The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery., Toriyama M, Lee C, Taylor SP, Duran I, Cohn DH, Bruel AL, Tabler JM, Drew K, Kelly MR, Kim S, Park TJ, Braun DA, Pierquin G, Biver A, Wagner K, Malfroot A, Panigrahi I, Franco B, Al-Lami HA, Yeung Y, Choi YJ, University of Washington Center for Mendelian Genomics, Duffourd Y, Faivre L, Rivière JB, Chen J, Liu KJ, Liu KJ, Marcotte EM, Hildebrandt F, Thauvin-Robinet C, Krakow D, Jackson PK, Wallingford JB., Nat Genet. June 1, 2016; 48 (6): 648-56.                              

Xenopus Limb bud morphogenesis., Keenan SR, Beck CW., Dev Dyn. March 1, 2016; 245 (3): 233-43.            

Frogs as integrative models for understanding digestive organ development and evolution., Womble M, Pickett M, Nascone-Yoder N., Semin Cell Dev Biol. March 1, 2016; 51 92-105.

Making muscle: Morphogenetic movements and molecular mechanisms of myogenesis in Xenopus laevis., Sabillo A, Ramirez J, Domingo CR., Semin Cell Dev Biol. March 1, 2016; 51 80-91.

Hedgehog inhibition causes complete loss of limb outgrowth and transformation of digit identity in Xenopus tropicalis., Stopper GF, Richards-Hrdlicka KL, Wagner GP., J Exp Zool B Mol Dev Evol. March 1, 2016; 326 (2): 110-24.

Localized JNK signaling regulates organ size during development., Willsey HR, Zheng X, Carlos Pastor-Pareja J, Willsey AJ, Beachy PA, Xu T., Elife. January 28, 2016; 5                       

Using Confocal Analysis of Xenopus laevis to Investigate Modulators of Wnt and Shh Morphogen Gradients., Fellgett SW, Ramsbottom SA, Maguire RJ, Cross S, O'Toole P, Pownall ME., J Vis Exp. December 14, 2015; (106): e53162.

Proteomics of Primary Cilia by Proximity Labeling., Mick DU, Rodrigues RB, Leib RD, Adams CM, Chien AS, Gygi SP, Nachury MV., Dev Cell. November 23, 2015; 35 (4): 497-512.

G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus., Miyagi A, Negishi T, Yamamoto TS, Ueno N., Dev Biol. November 1, 2015; 407 (1): 131-44.                                          

Gremlin1 induces anterior-posterior limb bifurcations in developing Xenopus limbs but does not enhance limb regeneration., Wang YH, Keenan SR, Lynn J, McEwan JC, Beck CW., Mech Dev. November 1, 2015; 138 Pt 3 256-67.                

Epigenetic modification maintains intrinsic limb-cell identity in Xenopus limb bud regeneration., Hayashi S, Kawaguchi A, Uchiyama I, Kawasumi-Kita A, Kobayashi T, Nishide H, Tsutsumi R, Tsuru K, Inoue T, Ogino H, Agata K, Tamura K, Yokoyama H., Dev Biol. October 15, 2015; 406 (2): 271-82.              

Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus., Thélie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, Borromeo MD, Kricha S, Lahaye F, Croce J, Cerda-Moya G, Ordoño Fernandez J, Bolle B, Lewis KE, Sander M, Pierani A, Schubert M, Johnson JE, Kintner CR, Pieler T, Van Lint C, Henningfeld KA, Bellefroid EJ, Van Campenhout C., Development. October 1, 2015; 142 (19): 3416-28.                                    

Noggin-Mediated Retinal Induction Reveals a Novel Interplay Between Bone Morphogenetic Protein Inhibition, Transforming Growth Factor β, and Sonic Hedgehog Signaling., Messina A, Lan L, Incitti T, Bozza A, Andreazzoli M, Vignali R, Cremisi F, Bozzi Y, Casarosa S., Stem Cells. August 1, 2015; 33 (8): 2496-508.

Evidence for an amphibian sixth digit., Hayashi S, Kobayashi T, Yano T, Kamiyama N, Egawa S, Seki R, Takizawa K, Okabe M, Yokoyama H, Tamura K., Zoological Lett. June 15, 2015; 1 17.                  

At new heights - endodermal lineages in development and disease., Ober EA, Grapin-Botton A., Development. June 1, 2015; 142 (11): 1912-1917.  

ATP4 and ciliation in the neuroectoderm and endoderm of Xenopus embryos and tadpoles., Walentek P, Hagenlocher C, Beyer T, Müller C, Feistel K, Schweickert A, Harland RM, Blum M., Data Brief. April 20, 2015; 4 22-31.            

Hematopoiesis: from start to immune reconstitution potential., Liang HC, Zúñiga-Pflücker JC., Stem Cell Res Ther. April 11, 2015; 6 52.        

Spatiotemporal integration of developmental cues in neural development., Borodinsky LN, Belgacem YH, Swapna I, Visina O, Balashova OA, Sequerra EB, Tu MK, Levin JB, Spencer KA, Castro PA, Hamilton AM, Shim S., Dev Neurobiol. April 1, 2015; 75 (4): 349-59.    

Inversion of Sonic hedgehog action on its canonical pathway by electrical activity., Belgacem YH, Borodinsky LN., Proc Natl Acad Sci U S A. March 31, 2015; 112 (13): 4140-5.                              

Dorsoventral patterning of the Xenopus eye involves differential temporal changes in the response of optic stalk and retinal progenitors to Hh signalling., Wang X, Lupo G, He R, Barsacchi G, Harris WA, Liu Y., Neural Dev. March 20, 2015; 10 7.              

Patterns of hypothalamic regionalization in amphibians and reptiles: common traits revealed by a genoarchitectonic approach., Domínguez L, González A, Moreno N., Front Neuroanat. February 3, 2015; 9 3.                

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