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Summary Expression Phenotypes Gene Literature (83) GO Terms (3) Nucleotides (101) Proteins (44) Interactants (134) Wiki
XB--5842249

Papers associated with slc22a6



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Transport of the natural sweetener stevioside and its aglycone steviol by human organic anion transporter (hOAT1; SLC22A6) and hOAT3 (SLC22A8)., Srimaroeng C, Chatsudthipong V, Aslamkhan AG, Pritchard JB., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 621-8.

Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1)., Fujita T, Brown C, Carlson EJ, Taylor T, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Fujita K, Castro R, Chen CW, Lin ET, Brett CM, Burchard EG, Ferrin TE, Huang CC, Leabman MK, Giacomini KM., Pharmacogenet Genomics. April 1, 2005; 15 (4): 201-9.

Organic anion transporter 3 is involved in the brain-to-blood efflux transport of thiopurine nucleobase analogs., Mori S, Ohtsuki S, Takanaga H, Kikkawa T, Kang YS, Terasaki T., J Neurochem. August 1, 2004; 90 (4): 931-41.

Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney., Youngblood GL, Sweet DH., Am J Physiol Renal Physiol. August 1, 2004; 287 (2): F236-44.

Mutation of amino acid 475 of rat organic cation transporter 2 (rOCT2) impairs organic cation transport., Bahn A, Hagos Y, Rudolph T, Burckhardt G., Biochimie. February 1, 2004; 86 (2): 133-6.

Molecular evidence of organic ion transporters in the rat adrenal cortex with adrenocorticotropin-regulated zonal expression., Béery E, Middel P, Bahn A, Willenberg HS, Hagos Y, Koepsell H, Bornstein SR, Müller GA, Burckhardt G, Steffgen J., Endocrinology. October 1, 2003; 144 (10): 4519-26.

Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells., Aslamkhan A, Han YH, Walden R, Sweet DH, Pritchard JB., Am J Physiol Renal Physiol. October 1, 2003; 285 (4): F775-83.

Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient., Sweet DH, Chan LM, Walden R, Yang XP, Miller DS, Pritchard JB., Am J Physiol Renal Physiol. April 1, 2003; 284 (4): F763-9.

Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells., Aslamkhan AG, Han YH, Yang XP, Zalups RK, Pritchard JB., Mol Pharmacol. March 1, 2003; 63 (3): 590-6.

Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: transport by the renal organic anion transporter-1., Koh AS, Simmons-Willis TA, Pritchard JB, Grassl SM, Ballatori N., Mol Pharmacol. October 1, 2002; 62 (4): 921-6.

Rat renal organic anion transporter rOAT1 mediates transport of urinary-excreted cephalosporins, but not of biliary-excreted cefoperazone., Uwai Y, Saito H, Inui K., Drug Metab Pharmacokinet. January 1, 2002; 17 (2): 125-9.

Molecular characterization of the renal organic anion transporter 1., Burckhardt G, Wolff NA, Bahn A., Cell Biochem Biophys. January 1, 2002; 36 (2-3): 169-74.

Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1., Pombrio JM, Giangreco A, Li L, Wempe MF, Anders MW, Sweet DH, Pritchard JB, Ballatori N., Mol Pharmacol. November 1, 2001; 60 (5): 1091-9.

Functional characterization of rat organic anion transporter 2 in LLC-PK1 cells., Morita N, Kusuhara H, Sekine T, Endou H, Sugiyama Y., J Pharmacol Exp Ther. September 1, 2001; 298 (3): 1179-84.

Isolation of a family of organic anion transporters from human liver and kidney., Sun W, Wu RR, van Poelje PD, Erion MD., Biochem Biophys Res Commun. May 4, 2001; 283 (2): 417-22.

Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter., Uwai Y, Saito H, Inui K., Eur J Pharmacol. December 1, 2000; 409 (1): 31-6.

Interaction and transport of thiazide diuretics, loop diuretics, and acetazolamide via rat renal organic anion transporter rOAT1., Uwai Y, Saito H, Hashimoto Y, Inui KI., J Pharmacol Exp Ther. October 1, 2000; 295 (1): 261-5.

Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs., Wada S, Tsuda M, Sekine T, Cha SH, Kimura M, Kanai Y, Endou H., J Pharmacol Exp Ther. September 1, 2000; 294 (3): 844-9.

Inhibitory effect of anti-diabetic agents on rat organic anion transporter rOAT1., Uwai Y, Saito H, Hashimoto Y, Inui K., Eur J Pharmacol. June 16, 2000; 398 (2): 193-7.

Cloning and functional characterization of the bile acid-sensitive methotrexate carrier from rat liver cells., Honscha W, Dötsch KU, Thomsen N, Petzinger E., Hepatology. June 1, 2000; 31 (6): 1296-304.

Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct., Pavlova A, Sakurai H, Leclercq B, Beier DR, Yu AS, Nigam SK., Am J Physiol Renal Physiol. April 1, 2000; 278 (4): F635-43.

The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1., Jariyawat S, Sekine T, Takeda M, Apiwattanakul N, Kanai Y, Sophasan S, Endou H., J Pharmacol Exp Ther. August 1, 1999; 290 (2): 672-7.

Transport of ochratoxin A by renal multispecific organic anion transporter 1., Tsuda M, Sekine T, Takeda M, Cha SH, Kanai Y, Kimura M, Endou H., J Pharmacol Exp Ther. June 1, 1999; 289 (3): 1301-5.

Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain., Kusuhara H, Sekine T, Utsunomiya-Tate N, Tsuda M, Kojima R, Cha SH, Sugiyama Y, Kanai Y, Endou H., J Biol Chem. May 7, 1999; 274 (19): 13675-80.

Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes., Apiwattanakul N, Sekine T, Chairoungdua A, Kanai Y, Nakajima N, Sophasan S, Endou H., Mol Pharmacol. May 1, 1999; 55 (5): 847-54.

Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3)., Race JE, Grassl SM, Williams WJ, Holtzman EJ., Biochem Biophys Res Commun. February 16, 1999; 255 (2): 508-14.

Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney., Uwai Y, Okuda M, Takami K, Hashimoto Y, Inui K., FEBS Lett. November 6, 1998; 438 (3): 321-4.

Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta., Kekuda R, Prasad PD, Wu X, Wang H, Fei YJ, Leibach FH, Ganapathy V., J Biol Chem. June 26, 1998; 273 (26): 15971-9.

Identification of multispecific organic anion transporter 2 expressed predominantly in the liver., Sekine T, Cha SH, Tsuda M, Apiwattanakul N, Nakajima N, Kanai Y, Endou H., FEBS Lett. June 12, 1998; 429 (2): 179-82.

Expression cloning and characterization of ROAT1. The basolateral organic anion transporter in rat kidney., Sweet DH, Wolff NA, Pritchard JB., J Biol Chem. November 28, 1997; 272 (48): 30088-95.

Expression cloning and characterization of a renal organic anion transporter from winter flounder., Wolff NA, Werner A, Burkhardt S, Burckhardt G., FEBS Lett. November 17, 1997; 417 (3): 287-91.

Expression cloning and characterization of a novel multispecific organic anion transporter., Sekine T, Watanabe N, Hosoyamada M, Kanai Y, Endou H., J Biol Chem. July 25, 1997; 272 (30): 18526-9.

Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney., Lopez-Nieto CE, You G, Bush KT, Barros EJ, Beier DR, Nigam SK., J Biol Chem. March 7, 1997; 272 (10): 6471-8.

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