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Summary Expression Phenotypes Gene Literature (136) GO Terms (2) Nucleotides (360) Proteins (46) Interactants (950) Wiki
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Spatial and temporal analysis of PCP protein dynamics during neural tube closure., Butler MT, Wallingford JB., Elife. August 6, 2018; 7                                         

Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels., Zheng W, Yang X, Hu R, Cai R, Hofmann L, Wang Z, Hu Q, Liu X, Bulkley D, Yu Y, Tang J, Flockerzi V, Cao Y, Cao E, Chen XZ., Nat Commun. June 13, 2018; 9 (1): 2302.            

Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2., Zheng W, Cai R, Hofmann L, Nesin V, Hu Q, Long W, Fatehi M, Liu X, Hussein S, Kong T, Li J, Light PE, Tang J, Flockerzi V, Tsiokas L, Chen XZ., Cell Rep. February 6, 2018; 22 (6): 1560-1573.          

Embryonic lethality is not sufficient to explain hourglass-like conservation of vertebrate embryos., Uchida Y, Uesaka M, Yamamoto T, Takeda H, Irie N., Evodevo. January 31, 2018; 9 7.    

Hyperinnervation improves Xenopus laevis limb regeneration., Mitogawa K, Makanae A, Satoh A., Dev Biol. January 15, 2018; 433 (2): 276-286.                    

A novel role for sox7 in Xenopus early primordial germ cell development: mining the PGC transcriptome., Butler AM, Owens DA, Wang L, King ML., Development. January 8, 2018; 145 (1):                                                 

The brain is required for normal muscle and nerve patterning during early Xenopus development., Herrera-Rincon C, Pai VP, Moran KM, Lemire JM, Levin M., Nat Commun. September 25, 2017; 8 (1): 587.              

The role of nitric oxide during embryonic epidermis development of Xenopus laevis., Tomankova S, Abaffy P, Sindelka R., Biol Open. June 15, 2017; 6 (6): 862-871.                        

The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma., Ignatius MS, Hayes MN, Lobbardi R, Chen EY, McCarthy KM, Sreenivas P, Motala Z, Durbin AD, Molodtsov A, Reeder S, Jin A, Sindiri S, Beleyea BC, Bhere D, Alexander MS, Shah K, Keller C, Linardic CM, Nielsen PG, Malkin D, Khan J, Langenau DM., Cell Rep. June 13, 2017; 19 (11): 2304-2318.            

Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis., Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.                        

Human amniotic fluid contaminants alter thyroid hormone signalling and early brain development in Xenopus embryos., Fini JB, Mughal BB, Le Mével S, Leemans M, Lettmann M, Spirhanzlova P, Affaticati P, Jenett A, Demeneix BA., Sci Rep. March 7, 2017; 7 43786.        

Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1., Alver RC, Chadha GS, Gillespie PJ, Blow JJ., Cell Rep. March 7, 2017; 18 (10): 2508-2520.                

Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development., Neilson KM, Abbruzzesse G, Kenyon K, Bartolo V, Krohn P, Alfandari D, Alfandari D, Moody SA., Dev Biol. January 15, 2017; 421 (2): 171-182.                    

High-throughput analysis reveals novel maternal germline RNAs crucial for primordial germ cell preservation and proper migration., Owens DA, Butler AM, Aguero TH, Newman KM, Van Booven D, King ML., Development. January 15, 2017; 144 (2): 292-304.                                                                                        

Persistent fibrosis, hypertrophy and sarcomere disorganisation after endoscopy-guided heart resection in adult Xenopus., Marshall L, Vivien C, Girardot F, Péricard L, Demeneix BA, Coen L, Chai N., PLoS One. January 1, 2017; 12 (3): e0173418.                

Chronic activation of the D156A point mutant of Channelrhodopsin-2 signals apoptotic cell death: the good and the bad., Perny M, Muri L, Dawson H, Kleinlogel S., Cell Death Dis. November 3, 2016; 7 (11): e2447.              

The MLL/Setd1b methyltransferase is required for the Spemann's organizer gene activation in Xenopus., Lin H, Min Z, Tao Q, Tao Q., Mech Dev. November 1, 2016; 142 1-9.              

Hedgehog-dependent E3-ligase Midline1 regulates ubiquitin-mediated proteasomal degradation of Pax6 during visual system development., Pfirrmann T, Jandt E, Ranft S, Lokapally A, Neuhaus H, Perron M, Hollemann T., Proc Natl Acad Sci U S A. September 6, 2016; 113 (36): 10103-8.                    

The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis., Villa M, Crotta S, Dingwell KS, Hirst EM, Gialitakis M, Ahlfors H, Smith JC, Stockinger B, Wack A., Nat Commun. August 24, 2016; 7 12652.            

Pharmacological profile of Ascaris suum ACR-16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissues., Abongwa M, Buxton SK, Courtot E, Charvet CL, Neveu C, McCoy CJ, Verma S, Robertson AP, Martin RJ., Br J Pharmacol. August 1, 2016; 173 (16): 2463-77.                

FACT Assists Base Excision Repair by Boosting the Remodeling Activity of RSC., Charles Richard JL, Shukla MS, Menoni H, Ouararhni K, Lone IN, Roulland Y, Papin C, Ben Simon E, Kundu T, Hamiche A, Angelov D, Dimitrov S., PLoS Genet. July 28, 2016; 12 (7): e1006221.            

HDAC3 But not HDAC2 Mediates Visual Experience-Dependent Radial Glia Proliferation in the Developing Xenopus Tectum., Gao J, Ruan H, Qi X, Tao Y, Guo X, Shen W., Front Cell Neurosci. May 6, 2016; 10 221.              

Measuring Absolute RNA Copy Numbers at High Temporal Resolution Reveals Transcriptome Kinetics in Development., Owens ND, Blitz IL, Lane MA, Patrushev I, Overton JD, Gilchrist MJ, Cho KW, Khokha MK., Cell Rep. January 26, 2016; 14 (3): 632-47.                                                  

Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer., Puvirajesinghe TM, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, Sebbagh M, Lopez M, Brech A, Finetti P, Charafe-Jauffret E, Chaffanet M, Castellano R, Restouin A, Marchetto S, Collette Y, Gonçalvès A, Macara I, Birnbaum D, Kodjabachian L, Johansen T, Borg JP., Nat Commun. January 12, 2016; 7 10318.                                  

CPEB and miR-15/16 Co-Regulate Translation of Cyclin E1 mRNA during Xenopus Oocyte Maturation., Wilczynska A, Git A, Argasinska J, Belloc E, Standart N., PLoS One. January 1, 2016; 11 (2): e0146792.            

The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway., Martinez S, Scerbo P, Giordano M, Daulat AM, Lhoumeau AC, Thomé V, Kodjabachian L, Borg JP., J Biol Chem. December 18, 2015; 290 (51): 30562-72.                        

Dual processing of sulfated steroids in the olfactory system of an anuran amphibian., Sansone A, Hassenklöver T, Offner T, Fu X, Holy TE, Manzini I., Front Cell Neurosci. September 23, 2015; 9 373.            

The Human Acid-Sensing Ion Channel ASIC1a: Evidence for a Homotetrameric Assembly State at the Cell Surface., van Bemmelen MX, Huser D, Gautschi I, Schild L., PLoS One. August 4, 2015; 10 (8): e0135191.              

Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin., Lu L, Gao Y, Zhang Z, Cao Q, Zhang X, Zou J, Cao Y., Dev Cell. June 22, 2015; 33 (6): 660-74.                                  

HDAC1 Regulates the Proliferation of Radial Glial Cells in the Developing Xenopus Tectum., Tao Y, Ruan H, Guo X, Li L, Shen W., PLoS One. March 16, 2015; 10 (3): e0120118.                

Endogenous gradients of resting potential instructively pattern embryonic neural tissue via Notch signaling and regulation of proliferation., Pai VP, Lemire JM, Paré JF, Lin G, Chen Y, Levin M., J Neurosci. March 11, 2015; 35 (10): 4366-85.                    

DNA interstrand cross-link repair requires replication-fork convergence., Zhang J, Dewar JM, Budzowska M, Motnenko A, Cohn MA, Walter JC., Nat Struct Mol Biol. March 1, 2015; 22 (3): 242-7.      

Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones., Piper M, Lee AC, van Horck FP, McNeilly H, Lu TB, Harris WA, Holt CE., Neural Dev. February 25, 2015; 10 3.            

Microarray identification of novel genes downstream of Six1, a critical factor in cranial placode, somite, and kidney development., Yan B, Neilson KM, Ranganathan R, Maynard T, Streit A, Moody SA., Dev Dyn. February 1, 2015; 244 (2): 181-210.                          

A novel PKD2L1 C-terminal domain critical for trimerization and channel function., Zheng W, Hussein S, Yang J, Huang J, Zhang F, Hernandez-Anzaldo S, Fernandez-Patron C, Cao Y, Cao Y, Zeng H, Tang J, Chen XZ., Sci Rep. January 12, 2015; 5 9460.              

FMRP regulates neurogenesis in vivo in Xenopus laevis tadpoles., Faulkner RL, Wishard TJ, Thompson CK, Liu HH, Cline HT., eNeuro. January 1, 2015; 2 (1): e0055.                

Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion., Jones LA, Villemant C, Starborg T, Salter A, Goddard G, Ruane P, Woodman PG, Papalopulu N, Woolner S, Allan VJ., J Cell Biol. November 24, 2014; 207 (4): 499-516.                  

Variable combinations of specific ephrin ligand/Eph receptor pairs control embryonic tissue separation., Rohani N, Parmeggiani A, Winklbauer R, Fagotto F., PLoS Biol. September 23, 2014; 12 (9): e1001955.              

A novel missense mutation in CCDC88C activates the JNK pathway and causes a dominant form of spinocerebellar ataxia., Tsoi H, Yu AC, Chen ZS, Ng NK, Chan AY, Yuen LY, Abrigo JM, Tsang SY, Tsui SK, Tong TM, Lo IF, Lam ST, Mok VC, Wong LK, Ngo JC, Lau KF, Chan TF, Chan HY., J Med Genet. September 1, 2014; .    

NEDD4L regulates convergent extension movements in Xenopus embryos via Disheveled-mediated non-canonical Wnt signaling., Zhang Y, Ding Y, Chen YG, Chen YG, Tao Q, Tao Q., Dev Biol. August 1, 2014; 392 (1): 15-25.                              

miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110., Song R, Walentek P, Sponer N, Klimke A, Lee JS, Dixon G, Harland R, Wan Y, Lishko P, Lize M, Kessel M, He L., Nature. June 5, 2014; 510 (7503): 115-20.                                

Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniates., Yajima H, Suzuki M, Ochi H, Ikeda K, Sato S, Yamamura K, Ogino H, Ueno N, Kawakami K., BMC Biol. May 29, 2014; 12 40.                        

Phospholipase C and diacylglycerol mediate olfactory responses to amino acids in the main olfactory epithelium of an amphibian., Sansone A, Hassenklöver T, Syed AS, Korsching SI, Manzini I., PLoS One. January 17, 2014; 9 (1): e87721.          

FoxA4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos., Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL., PLoS One. January 1, 2014; 9 (10): e110559.                              

Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence., Rodríguez-Seguel E, Mah N, Naumann H, Pongrac IM, Cerdá-Esteban N, Fontaine JF, Wang Y, Chen W, Andrade-Navarro MA, Spagnoli FM., Genes Dev. September 1, 2013; 27 (17): 1932-46.    

The centriolar satellite protein SSX2IP promotes centrosome maturation., Bärenz F, Inoue D, Yokoyama H, Tegha-Dunghu J, Freiss S, Draeger S, Mayilo D, Cado I, Merker S, Klinger M, Hoeckendorf B, Pilz S, Hupfeld K, Steinbeisser H, Lorenz H, Ruppert T, Wittbrodt J, Gruss OJ., J Cell Biol. July 8, 2013; 202 (1): 81-95.              

Inositol kinase and its product accelerate wound healing by modulating calcium levels, Rho GTPases, and F-actin assembly., Soto X, Li J, Lea R, Dubaissi E, Papalopulu N, Amaya E., Proc Natl Acad Sci U S A. July 2, 2013; 110 (27): 11029-34.                                      

The hypoxia factor Hif-1α controls neural crest chemotaxis and epithelial to mesenchymal transition., Barriga EH, Maxwell PH, Reyes AE, Mayor R., J Cell Biol. May 27, 2013; 201 (5): 759-76.                  

Proteolysis of Xenopus Cip-type CDK inhibitor, p16Xic2, is regulated by PCNA binding and CDK2 phosphorylation., Zhu XN, Kim DH, Lin HR, Budhavarapu VN, Rosenbaum HB, Mueller PR, Yew PR., Cell Div. April 22, 2013; 8 (1): 5.              

Suv4-20h histone methyltransferases promote neuroectodermal differentiation by silencing the pluripotency-associated Oct-25 gene., Nicetto D, Hahn M, Jung J, Schneider TD, Straub T, David R, Schotta G, Rupp RA., PLoS Genet. January 1, 2013; 9 (1): e1003188.                                                                

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