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Summary Expression Phenotypes Gene Literature (100) GO Terms (2) Nucleotides (331) Proteins (82) Interactants (125) Wiki
XB--948121

Papers associated with arfgap1



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Location and orientation of minK within the I(Ks) potassium channel complex., Tapper AR, George AL., J Biol Chem. October 12, 2001; 276 (41): 38249-54.


Properties and function of KCNQ1 K+ channels isolated from the rectal gland of Squalus acanthias., Kerst G, Beschorner U, Unsöld B, von Hahn T, Schreiber R, Greger R, Gerlach U, Lang HJ, Kunzelmann K, Bleich M., Pflugers Arch. October 1, 2001; 443 (1): 146-54.


A novel long-QT 5 gene mutation in the C-terminus (V109I) is associated with a mild phenotype., Schulze-Bahr E, Schwarz M, Hauenschild S, Wedekind H, Funke H, Haverkamp W, Breithardt G, Pongs O, Isbrandt D, Hoffman S., J Mol Med (Berl). September 1, 2001; 79 (9): 504-9.


Chromanol 293B, a blocker of the slow delayed rectifier K+ current (IKs), inhibits the CFTR Cl- current., Bachmann A, Quast U, Russ U., Naunyn Schmiedebergs Arch Pharmacol. June 1, 2001; 363 (6): 590-6.


Short- and long-term effects of amiodarone on the two components of cardiac delayed rectifier K(+) current., Kamiya K, Nishiyama A, Yasui K, Hojo M, Sanguinetti MC, Kodama I., Circulation. March 6, 2001; 103 (9): 1317-24.


Cloning and function of the rat colonic epithelial K+ channel KVLQT1., Kunzelmann K, Hübner M, Schreiber R, Levy-Holzman R, Garty H, Bleich M, Warth R, Slavik M, von Hahn T, Greger R., J Membr Biol. January 15, 2001; 179 (2): 155-64.


Expression and function of colonic epithelial KvLQT1 K+ channels., Kunzelmann K, Bleich M, Warth R, Levy-Holzman R, Garty H, Schreiber R., Clin Exp Pharmacol Physiol. January 1, 2001; 28 (1-2): 79-83.


KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel., Tinel N, Diochot S, Borsotto M, Lazdunski M, Barhanin J., EMBO J. December 1, 2000; 19 (23): 6326-30.


Mechanisms of I(Ks) suppression in LQT1 mutants., Bianchi L, Priori SG, Napolitano C, Surewicz KA, Dennis AT, Memmi M, Schwartz PJ, Brown AM., Am J Physiol Heart Circ Physiol. December 1, 2000; 279 (6): H3003-11.


A structural basis for drug-induced long QT syndrome., Mitcheson JS, Chen J, Lin M, Culberson C, Sanguinetti MC., Proc Natl Acad Sci U S A. October 24, 2000; 97 (22): 12329-33.


MinK endows the I(Ks) potassium channel pore with sensitivity to internal tetraethylammonium., Sesti F, Tai KK, Goldstein SA., Biophys J. September 1, 2000; 79 (3): 1369-78.


MinK subdomains that mediate modulation of and association with KvLQT1., Tapper AR, George AL., J Gen Physiol. September 1, 2000; 116 (3): 379-90.          


Functional coupling of human beta 3-adrenoreceptors to the KvLQT1/MinK potassium channel., Kathöfer S, Zhang W, Karle C, Thomas D, Schoels W, Kiehn J., J Biol Chem. September 1, 2000; 275 (35): 26743-7.


Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias., Napolitano C, Schwartz PJ, Brown AM, Ronchetti E, Bianchi L, Pinnavaia A, Acquaro G, Priori SG., J Cardiovasc Electrophysiol. June 1, 2000; 11 (6): 691-6.


Molecular basis for differential sensitivity of KCNQ and I(Ks) channels to the cognitive enhancer XE991., Wang HS, Brown BS, McKinnon D, Cohen IS., Mol Pharmacol. June 1, 2000; 57 (6): 1218-23.


KChAP as a chaperone for specific K(+) channels., Kuryshev YA, Gudz TI, Brown AM, Wible BA., Am J Physiol Cell Physiol. May 1, 2000; 278 (5): C931-41.


A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly., Schmitt N, Schwarz M, Peretz A, Abitbol I, Attali B, Pongs O., EMBO J. February 1, 2000; 19 (3): 332-40.


A constitutively open potassium channel formed by KCNQ1 and KCNE3., Schroeder BC, Waldegger S, Fehr S, Bleich M, Warth R, Greger R, Jentsch TJ., Nature. January 13, 2000; 403 (6766): 196-9.


Analysis of the human KCNH2(HERG) gene: identification and characterization of a novel mutation Y667X associated with long QT syndrome and a non-pathological 9 bp insertion., Paulussen A, Yang P, Pangalos M, Verhasselt P, Marrannes R, Verfaille C, Vandenberk I, Crabbe R, Konings F, Luyten W, Armstrong M., Hum Mutat. January 1, 2000; 15 (5): 483.


Molecular and functional characterization of the small Ca(2+)-regulated K+ channel (rSK4) of colonic crypts., Warth R, Hamm K, Bleich M, Kunzelmann K, von Hahn T, Schreiber R, Ullrich E, Mengel M, Trautmann N, Kindle P, Schwab A, Greger R., Pflugers Arch. September 1, 1999; 438 (4): 437-44.


Stilbenes and fenamates rescue the loss of I(KS) channel function induced by an LQT5 mutation and other IsK mutants., Abitbol I, Peretz A, Lerche C, Busch AE, Attali B., EMBO J. August 2, 1999; 18 (15): 4137-48.


Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome., Bianchi L, Shen Z, Dennis AT, Priori SG, Napolitano C, Ronchetti E, Bryskin R, Schwartz PJ, Brown AM., Hum Mol Genet. August 1, 1999; 8 (8): 1499-507.


Long QT syndrome-associated mutations in the S4-S5 linker of KvLQT1 potassium channels modify gating and interaction with minK subunits., Franqueza L, Lin M, Shen J, Splawski I, Keating MT, Sanguinetti MC., J Biol Chem. July 23, 1999; 274 (30): 21063-70.


Functional effects of mutations in KvLQT1 that cause long QT syndrome., Wang Z, Tristani-Firouzi M, Xu Q, Lin M, Keating MT, Sanguinetti MC., J Cardiovasc Electrophysiol. June 1, 1999; 10 (6): 817-26.


Modulation of HERG potassium channels by extracellular magnesium and quinidine., Po SS, Wang DW, Yang IC, Johnson JP, Nie L, Bennett PB., J Cardiovasc Pharmacol. February 1, 1999; 33 (2): 181-5.


Single-channel properties of IKs potassium channels., Yang Y, Sigworth FJ., J Gen Physiol. December 1, 1998; 112 (6): 665-78.                  


Single-channel characteristics of wild-type IKs channels and channels formed with two minK mutants that cause long QT syndrome., Sesti F, Goldstein SA., J Gen Physiol. December 1, 1998; 112 (6): 651-63.                    


Increase of the single-channel conductance of KvLQT1 potassium channels induced by the association with minK., Pusch M., Pflugers Arch. December 1, 1998; 437 (1): 172-4.


Independent and exclusive modulation of cardiac delayed rectifying K+ current by protein kinase C and protein kinase A., Lo CF, Numann R., Circ Res. November 16, 1998; 83 (10): 995-1002.


Divalent cations inhibit IsK/KvLQT1 channels in excised membrane patches of strial marginal cells., Shen Z, Marcus DC., Hear Res. September 1, 1998; 123 (1-2): 157-67.


Activation and inactivation of homomeric KvLQT1 potassium channels., Pusch M, Magrassi R, Wollnik B, Conti F., Biophys J. August 1, 1998; 75 (2): 785-92.


Functional expression of two KvLQT1-related potassium channels responsible for an inherited idiopathic epilepsy., Yang WP, Levesque PC, Little WA, Conder ML, Ramakrishnan P, Neubauer MG, Blanar MA., J Biol Chem. July 31, 1998; 273 (31): 19419-23.


A novel benzodiazepine that activates cardiac slow delayed rectifier K+ currents., Salata JJ, Jurkiewicz NK, Wang J, Evans BE, Orme HT, Sanguinetti MC., Mol Pharmacol. July 1, 1998; 54 (1): 220-30.


Voltage-dependent inactivation of the human K+ channel KvLQT1 is eliminated by association with minimal K+ channel (minK) subunits., Tristani-Firouzi M, Sanguinetti MC., J Physiol. July 1, 1998; 510 ( Pt 1) 37-45.


A recessive variant of the Romano-Ward long-QT syndrome?, Priori SG, Schwartz PJ, Napolitano C, Bianchi L, Dennis A, De Fusco M, Brown AM, Casari G., Circulation. June 23, 1998; 97 (24): 2420-5.


Gating of I(sK) channels expressed in Xenopus oocytes., Tzounopoulos T, Maylie J, Adelman JP., Biophys J. May 1, 1998; 74 (5): 2299-305.


KQT2, a new putative potassium channel family produced by alternative splicing. Isolation, genomic structure, and alternative splicing of the putative potassium channels., Nakamura M, Watanabe H, Kubo Y, Yokoyama M, Matsumoto T, Sasai H, Nishi Y., Recept Channels. January 1, 1998; 5 (5): 255-71.


Mutations in the hminK gene cause long QT syndrome and suppress IKs function., Splawski I, Tristani-Firouzi M, Lehmann MH, Sanguinetti MC, Keating MT., Nat Genet. November 1, 1997; 17 (3): 338-40.


Suppression of slow delayed rectifier current by a truncated isoform of KvLQT1 cloned from normal human heart., Jiang M, Tseng-Crank J, Tseng GN., J Biol Chem. September 26, 1997; 272 (39): 24109-12.


Dominant-negative KvLQT1 mutations underlie the LQT1 form of long QT syndrome., Shalaby FY, Levesque PC, Yang WP, Little WA, Conder ML, Jenkins-West T, Blanar MA., Circulation. September 16, 1997; 96 (6): 1733-6.


The role of the IsK protein in the specific pharmacological properties of the IKs channel complex., Busch AE, Busch GL, Ford E, Suessbrich H, Lang HJ, Greger R, Kunzelmann K, Attali B, Stühmer W., Br J Pharmacol. September 1, 1997; 122 (2): 187-9.


Block by propofol and thiopentone of the min K current (IsK) expressed in Xenopus oocytes., Heath BM, Terrar DA., Naunyn Schmiedebergs Arch Pharmacol. September 1, 1997; 356 (3): 404-9.


A minK-HERG complex regulates the cardiac potassium current I(Kr)., McDonald TV, Yu Z, Ming Z, Palma E, Meyers MB, Wang KW, Goldstein SA, Fishman GI., Nature. July 17, 1997; 388 (6639): 289-92.


Properties and regulation of the minK potassium channel protein., Kaczmarek LK, Blumenthal EM., Physiol Rev. July 1, 1997; 77 (3): 627-41.


KvLQT1, a voltage-gated potassium channel responsible for human cardiac arrhythmias., Yang WP, Levesque PC, Little WA, Conder ML, Shalaby FY, Blanar MA., Proc Natl Acad Sci U S A. April 15, 1997; 94 (8): 4017-21.


Role of the ISK protein in the IminK channel complex., Busch AE, Suessbrich H., Trends Pharmacol Sci. January 1, 1997; 18 (1): 26-9.


Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel., Sanguinetti MC, Curran ME, Zou A, Shen J, Spector PS, Atkinson DL, Keating MT., Nature. November 7, 1996; 384 (6604): 80-3.


K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current., Barhanin J, Lesage F, Guillemare E, Fink M, Lazdunski M, Romey G., Nature. November 7, 1996; 384 (6604): 78-80.


Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia., Sanguinetti MC, Curran ME, Spector PS, Keating MT., Proc Natl Acad Sci U S A. March 5, 1996; 93 (5): 2208-12.


A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel., Sanguinetti MC, Jiang C, Curran ME, Keating MT., Cell. April 21, 1995; 81 (2): 299-307.

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