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Summary Expression Phenotypes Gene Literature (550) GO Terms (6) Nucleotides (309) Proteins (58) Interactants (2147) Wiki
XB--485219

Papers associated with otx2



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138 ???displayGene.morpholinoPapers???

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The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C., Elife. January 14, 2020; 9                                                                                               

Modeling Bainbridge-Ropers Syndrome in Xenopus laevis Embryos., Lichtig H, Artamonov A, Polevoy H, Reid CD, Bielas SL, Frank D., Front Physiol. January 1, 2020; 11 75.                    

HCN2 Channel-Induced Rescue of Brain Teratogenesis via Local and Long-Range Bioelectric Repair., Pai VP, Cervera J, Mafe S, Willocq V, Lederer EK, Levin M., Front Cell Neurosci. January 1, 2020; 14 136.                      

MiR-9 and the Midbrain-Hindbrain Boundary: A Showcase for the Limited Functional Conservation and Regulatory Complexity of MicroRNAs., Alwin Prem Anand A, Alvarez-Bolado G, Wizenmann A., Front Cell Dev Biol. January 1, 2020; 8 586158.  

Preventing Ethanol-Induced Brain and Eye Morphology Defects Using Optogenetics., Pai VP, Adams DS., Bioelectricity. December 1, 2019; 1 (4): 260-272.

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Kuznetsov JN, Aguero TH, Owens DA, Kurtenbach S, Field MG, Durante MA, Rodriguez DA, King ML, Harbour JW., Sci Adv. September 18, 2019; 5 (9): eaax1738.        

Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome., Greenberg RS, Long HK, Swigut T, Wysocka J., Cell. September 5, 2019; 178 (6): 1421-1436.e24.                                

Microsyntenic Clusters Reveal Conservation of lncRNAs in Chordates Despite Absence of Sequence Conservation., Herrera-Úbeda C, Marín-Barba M, Navas-Pérez E, Gravemeyer J, Albuixech-Crespo B, Wheeler GN, Garcia-Fernàndez J., Biology (Basel). August 24, 2019; 8 (3):             

Evolution of cis-regulatory modules for the head organizer gene goosecoid in chordates: comparisons between Branchiostoma and Xenopus., Yasuoka Y, Tando Y, Kubokawa K, Taira M., Zoological Lett. August 2, 2019; 5 27.                

Cdc2-like kinase 2 (Clk2) promotes early neural development in Xenopus embryos., Virgirinia RP, Jahan N, Okada M, Takebayashi-Suzuki K, Yoshida H, Nakamura M, Akao H, Yoshimoto Y, Fatchiyah F, Ueno N, Suzuki A., Dev Growth Differ. August 1, 2019; 61 (6): 365-377.                              

Jmjd6a regulates GSK3β RNA splicing in Xenopus laevis eye development., Shin JY, Son J, Kim WS, Gwak J, Ju BG., PLoS One. July 30, 2019; 14 (7): e0219800.                      

What are the roles of retinoids, other morphogens, and Hox genes in setting up the vertebrate body axis?, Durston AJ., Genesis. July 1, 2019; 57 (7-8): e23296.            

Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation., Paraiso KD, Blitz IL, Coley M, Cheung J, Sudou N, Taira M, Cho KWY., Cell Rep. June 4, 2019; 27 (10): 2962-2977.e5.                          

Mechanistic insights from the LHX1-driven molecular network in building the embryonic head., McMahon R, Sibbritt T, Salehin N, Osteil P, Tam PPL., Dev Growth Differ. June 1, 2019; 61 (5): 327-336.

Barhl2 maintains T cell factors as repressors and thereby switches off the Wnt/β-Catenin response driving Spemann organizer formation., Sena E, Rocques N, Borday C, Muhamad Amin HS, Parain K, Sitbon D, Chesneau A, Durand BC., Development. May 22, 2019; 146 (10):                                             

Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis., Paraiso KD, Blitz IL, Zhou JJ, Cho KWY., Dev Cell. May 20, 2019; 49 (4): 643-650.e3.        

Leukemia inhibitory factor signaling in Xenopus embryo: Insights from gain of function analysis and dominant negative mutant of the receptor., Jalvy S, Veschambre P, Fédou S, Rezvani HR, Thézé N, Thiébaud P., Dev Biol. March 15, 2019; 447 (2): 200-213.                                  

The C-terminus of the retinal homeobox (rax) gene product modulates transcription in a context-dependent manner., Buescher JL, El-Hodiri HM., Mol Vis. February 23, 2019; 25 165-173.      

Nucleotide receptor P2RY4 is required for head formation via induction and maintenance of head organizer in Xenopus laevis., Harata A, Hirakawa M, Sakuma T, Yamamoto T, Hashimoto C., Dev Growth Differ. February 1, 2019; 61 (2): 186-197.                                

Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development., Kim Y, Jeong Y, Kwon K, Ismail T, Lee HK, Kim C, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Kwon T, Lee HS., Epigenetics Chromatin. December 6, 2018; 11 (1): 72.                

AKT signaling displays multifaceted functions in neural crest development., Sittewelle M, Monsoro-Burq AH., Dev Biol. December 1, 2018; 444 Suppl 1 S144-S155.

WDR5 regulates left-right patterning via chromatin-dependent and -independent functions., Kulkarni SS, Khokha MK., Development. November 28, 2018; 145 (23):                 

Assembly of protein complexes restricts diffusion of Wnt3a proteins., Takada R, Mii Y, Krayukhina E, Maruyama Y, Mio K, Sasaki Y, Shinkawa T, Pack CG, Sako Y, Sato C, Uchiyama S, Takada S., Commun Biol. October 10, 2018; 1 165.              

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Ding Y, Colozza G, Sosa EA, Moriyama Y, Rundle S, Salwinski L, De Robertis EM., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.                    

Serine Threonine Kinase Receptor-Associated Protein Deficiency Impairs Mouse Embryonic Stem Cells Lineage Commitment Through CYP26A1-Mediated Retinoic Acid Homeostasis., Jin L, Chang C, Pawlik KM, Datta A, Johnson LM, Vu T, Napoli JL, Datta PK., Stem Cells. September 1, 2018; 36 (9): 1368-1379.                      

Nosip functions during vertebrate eye and cranial cartilage development., Flach H, Krieg J, Hoffmeister M, Dietmann P, Reusch A, Wischmann L, Kernl B, Riegger R, Oess S, Kühl SJ., Dev Dyn. September 1, 2018; 247 (9): 1070-1082.                

Xbra and Smad-1 cooperate to activate the transcription of neural repressor ventx1.1 in Xenopus embryos., Kumar S, Kumar S, Umair Z, Yoon J, Lee U, Kim SC, Park JB, Lee JY, Kim J., Sci Rep. July 30, 2018; 8 (1): 11391.                

Roles of Xenopus chemokine ligand CXCLh (XCXCLh) in early embryogenesis., Goto T, Ito Y, Michiue T., Dev Growth Differ. May 1, 2018; 60 (4): 226-238.              

Head formation requires Dishevelled degradation that is mediated by March2 in concert with Dapper1., Lee H, Lee H, Cheong SM, Han W, Koo Y, Jo SB, Cho GS, Yang JS, Kim S, Han JK., Development. April 10, 2018; 145 (7):               

Retinoic acid promotes stem cell differentiation and embryonic development by transcriptionally activating CFTR., Li X, Fok KL, Guo J, Wang Y, Liu Z, Chen Z, Wang C, Ruan YC, Yu SS, Zhao H, Wu J, Jiang X, Chan HC., Biochim Biophys Acta Mol Cell Res. April 1, 2018; 1865 (4): 605-615.

Coordinated regulation of the dorsal-ventral and anterior-posterior patterning of Xenopus embryos by the BTB/POZ zinc finger protein Zbtb14., Takebayashi-Suzuki K, Konishi H, Miyamoto T, Nagata T, Uchida M, Suzuki A., Dev Growth Differ. April 1, 2018; 60 (3): 158-173.          

Phosphorylation states change Otx2 activity for cell proliferation and patterning in the Xenopus embryo., Satou Y, Minami K, Hosono E, Okada H, Yasuoka Y, Shibano T, Tanaka T, Taira M., Development. March 12, 2018; 145 (5):                             

HCN2 Rescues brain defects by enforcing endogenous voltage pre-patterns., Pai VP, Pietak A, Willocq V, Ye B, Shi NQ, Levin M., Nat Commun. March 8, 2018; 9 (1): 998.                        

RAPGEF5 Regulates Nuclear Translocation of β-Catenin., Griffin JN, Del Viso F, Duncan AR, Robson A, Hwang W, Kulkarni S, Liu KJ, Liu KJ, Khokha MK., Dev Cell. January 22, 2018; 44 (2): 248-260.e4.                                                

Cloning and spatiotemporal expression of Xenopus laevis Apolipoprotein CI., Sridharan J, Haremaki T, Weinstein DC., PLoS One. January 18, 2018; 13 (1): e0191470.                

HMG-box factor SoxD/Sox15 and homeodomain-containing factor Xanf1/Hesx1 directly interact and regulate the expression of Xanf1/Hesx1 during early forebrain development in Xenopus laevis., Martynova NY, Eroshkin FM, Оrlov EE, Zaraisky AG., Gene. January 5, 2018; 638 52-59.      

Roles for Xenopus aquaporin-3b (aqp3.L) during gastrulation: Fibrillar fibronectin and tissue boundary establishment in the dorsal margin., Forecki J, Van Antwerp DJ, Lujan SM, Merzdorf CS., Dev Biol. January 1, 2018; 433 (1): 3-16.                      

An atlas of Wnt activity during embryogenesis in Xenopus tropicalis., Borday C, Parain K, Thi Tran H, Vleminckx K, Vleminckx K, Perron M, Monsoro-Burq AH., PLoS One. January 1, 2018; 13 (4): e0193606.                

PFKFB4 control of AKT signaling is essential for premigratory and migratory neural crest formation., Figueiredo AL, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, Monsoro-Burq AH., Development. November 15, 2017; 144 (22): 4183-4194.                                

Maternal Gdf3 is an obligatory cofactor in Nodal signaling for embryonic axis formation in zebrafish., Bisgrove BW, Su YC, Yost HJ., Elife. November 15, 2017; 6                 

A Nonredundant Role for the TRPM6 Channel in Neural Tube Closure., Komiya Y, Bai Z, Cai N, Lou L, Al-Saadi N, Mezzacappa C, Habas R, Runnels LW., Sci Rep. November 15, 2017; 7 (1): 15623.                    

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

Vestigial-like 3 is a novel Ets1 interacting partner and regulates trigeminal nerve formation and cranial neural crest migration., Simon E, Thézé N, Fédou S, Thiébaud P, Faucheux C., Biol Open. October 15, 2017; 6 (10): 1528-1540.                                  

The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus., Zhu X, Xing R, Tan R, Dai R, Tao Q, Tao Q., Mech Dev. October 1, 2017; 147 28-36.              

Mouth development., Chen J, Jacox LA, Saldanha F, Sive H., Wiley Interdiscip Rev Dev Biol. September 1, 2017; 6 (5):               

Nodal/Activin Pathway is a Conserved Neural Induction Signal in Chordates., Le Petillon Y, Luxardi G, Scerbo P, Cibois M, Leon A, Subirana L, Irimia M, Kodjabachian L, Escriva H, Bertrand S., Nat Ecol Evol. August 1, 2017; 1 (8): 1192-1200.                                

Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula., Ding Y, Colozza G, Zhang K, Moriyama Y, Ploper D, Sosa EA, Benitez MDJ, De Robertis EM., Dev Biol. June 15, 2017; 426 (2): 176-187.                                  

Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing., Popov IK, Kwon T, Crossman DK, Crowley MR, Wallingford JB, Chang C., Dev Biol. June 15, 2017; 426 (2): 429-441.                    

Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis., Watanabe M, Yasuoka Y, Mawaribuchi S, Kuretani A, Ito M, Kondo M, Ochi H, Ogino H, Fukui A, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 301-324.                          

The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning., Rauschenberger V, Bernkopf DB, Krenn S, Jalal K, Heller J, Behrens J, Gentzel M, Schambony A., Development. June 15, 2017; 144 (12): 2234-2247.                                      

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