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Summary Expression Phenotypes Gene Literature (227) GO Terms (8) Nucleotides (258) Proteins (48) Interactants (1248) Wiki
XB--491120

Papers associated with tubb2b



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An oncologist׳s friend: How Xenopus contributes to cancer research., Hardwick LJ, Philpott A., Dev Biol. December 15, 2015; 408 (2): 180-7.  

Heritable CRISPR/Cas9-mediated targeted integration in Xenopus tropicalis., Shi Z, Wang F, Cui Y, Liu Z, Guo X, Zhang Y, Deng Y, Zhao H, Chen Y, Chen Y., FASEB J. December 1, 2015; 29 (12): 4914-23.

CDC174, a novel component of the exon junction complex whose mutation underlies a syndrome of hypotonia and psychomotor developmental delay., Volodarsky M, Lichtig H, Leibson T, Sadaka Y, Kadir R, Perez Y, Liani-Leibson K, Gradstein L, Shaco-Levy R, Shorer Z, Frank D, Birk OS., Hum Mol Genet. November 15, 2015; 24 (22): 6485-91.

Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus., Thélie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, Borromeo MD, Kricha S, Lahaye F, Croce J, Cerda-Moya G, Ordoño Fernandez J, Bolle B, Lewis KE, Sander M, Pierani A, Schubert M, Johnson JE, Kintner CR, Pieler T, Van Lint C, Henningfeld KA, Bellefroid EJ, Van Campenhout C., Development. October 1, 2015; 142 (19): 3416-28.                                    

Expression of the cyp19a1 gene in the adult brain of Xenopus is neuronal and not sexually dimorphic., Coumailleau P, Kah O., Gen Comp Endocrinol. September 15, 2015; 221 203-12.        

Kcnip1 a Ca²⁺-dependent transcriptional repressor regulates the size of the neural plate in Xenopus., Néant I, Mellström B, Gonzalez P, Naranjo JR, Moreau M, Leclerc C., Biochim Biophys Acta. September 1, 2015; 1853 (9): 2077-85.  

Multi-site phosphorylation regulates NeuroD4 activity during primary neurogenesis: a conserved mechanism amongst proneural proteins., Hardwick LJ, Philpott A., Neural Dev. June 18, 2015; 10 15.                  

Microtubule-associated protein tau promotes neuronal class II β-tubulin microtubule formation and axon elongation in embryonic Xenopus laevis., Liu Y, Wang C, Wang C, Destin G, Szaro BG., Eur J Neurosci. May 1, 2015; 41 (10): 1263-75.            

Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma., Wylie LA, Hardwick LJ, Papkovskaia TD, Thiele CJ, Philpott A., Dis Model Mech. May 1, 2015; 8 (5): 429-41.                

Expression of a novel serine/threonine kinase gene, Ulk4, in neural progenitors during Xenopus laevis forebrain development., Domínguez L, Schlosser G, Shen S., Neuroscience. April 2, 2015; 290 61-79.  

Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation., Zhang X, Cheong SM, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X., Dev Cell. March 23, 2015; 32 (6): 719-30.                                  

The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Acosta H, Iliev D, Grahn TH, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM., Development. March 15, 2015; 142 (6): 1146-58.                                    

Regulation of ECM degradation and axon guidance by growth cone invadosomes., Santiago-Medina M, Gregus KA, Nichol RH, O'Toole SM, Gomez TM., Development. February 1, 2015; 142 (3): 486-96.                        

aPKC phosphorylates p27Xic1, providing a mechanistic link between apicobasal polarity and cell-cycle control., Sabherwal N, Thuret R, Lea R, Stanley P, Papalopulu N., Dev Cell. December 8, 2014; 31 (5): 559-71.                          

Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development., Zhang S, Li J, Lea R, Vleminckx K, Vleminckx K, Amaya E., Development. December 1, 2014; 141 (24): 4794-805.                            

Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression., Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW., Dev Biol. November 15, 2014; 395 (2): 287-98.                    

Phosphorylation in intrinsically disordered regions regulates the activity of Neurogenin2., McDowell GS, Hindley CJ, Lippens G, Landrieu I, Philpott A., BMC Biochem. November 6, 2014; 15 24.        

The splicing factor PQBP1 regulates mesodermal and neural development through FGF signaling., Iwasaki Y, Thomsen GH., Development. October 1, 2014; 141 (19): 3740-51.                                          

Complex domain interactions regulate stability and activity of closely related proneural transcription factors., McDowell GS, Hardwick LJ, Philpott A., Biochem Biophys Res Commun. August 8, 2014; 450 (4): 1283-90.        

Sp8 regulates inner ear development., Chung HA, Medina-Ruiz S, Harland RM., Proc Natl Acad Sci U S A. April 29, 2014; 111 (17): 6329-34.                                                    

Ascl1 as a novel player in the Ptf1a transcriptional network for GABAergic cell specification in the retina., Mazurier N, Parain K, Parlier D, Pretto S, Hamdache J, Vernier P, Locker M, Bellefroid E, Perron M., PLoS One. March 18, 2014; 9 (3): e92113.                        

The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube., Hanotel J, Bessodes N, Thélie A, Hedderich M, Parain K, Van Driessche B, Brandão Kde O, Kricha S, Jorgensen MC, Grapin-Botton A, Serup P, Van Lint C, Perron M, Pieler T, Henningfeld KA, Bellefroid EJ., Dev Biol. February 15, 2014; 386 (2): 340-57.                                                                    

FoxA4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos., Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL., PLoS One. January 1, 2014; 9 (10): e110559.                              

Maturin is a novel protein required for differentiation during primary neurogenesis., Martinez-De Luna RI, Ku RY, Lyou Y, Zuber ME., Dev Biol. December 1, 2013; 384 (1): 26-40.                        

Regulation of neurogenesis by Fgf8a requires Cdc42 signaling and a novel Cdc42 effector protein., Hulstrand AM, Houston DW., Dev Biol. October 15, 2013; 382 (2): 385-99.                              

NumbL is essential for Xenopus primary neurogenesis., Nieber F, Hedderich M, Jahn O, Pieler T, Henningfeld KA., BMC Dev Biol. October 14, 2013; 13 36.                          

In vivo T-box transcription factor profiling reveals joint regulation of embryonic neuromesodermal bipotency., Gentsch GE, Owens ND, Martin SR, Piccinelli P, Faial T, Trotter MW, Gilchrist MJ, Smith JC., Cell Rep. September 26, 2013; 4 (6): 1185-96.                              

Xenopus laevis nucleotide binding protein 1 (xNubp1) is important for convergent extension movements and controls ciliogenesis via regulation of the actin cytoskeleton., Ioannou A, Santama N, Skourides PA., Dev Biol. August 15, 2013; 380 (2): 243-58.                                  

MRAS GTPase is a novel stemness marker that impacts mouse embryonic stem cell plasticity and Xenopus embryonic cell fate., Mathieu ME, Faucheux C, Saucourt C, Soulet F, Gauthereau X, Fédou S, Trouillas M, Thézé N, Thiébaud P, Boeuf H., Development. August 1, 2013; 140 (16): 3311-22.              

ERF and ETV3L are retinoic acid-inducible repressors required for primary neurogenesis., Janesick A, Abbey R, Chung C, Liu S, Taketani M, Blumberg B., Development. August 1, 2013; 140 (15): 3095-106.                                                              

Neurogenesis is required for behavioral recovery after injury in the visual system of Xenopus laevis., McKeown CR, Sharma P, Sharipov HE, Shen W, Cline HT., J Comp Neurol. July 1, 2013; 521 (10): 2262-78.              

The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F, Hu W, Xian J, Ohnuma S, Brenton JD., Dev Biol. July 1, 2013; 379 (1): 16-27.                            

Mitotic spindle scaling during Xenopus development by kif2a and importin α., Wilbur JD, Heald R., Elife. February 19, 2013; 2 e00290.                  

The Xenopus doublesex-related gene Dmrt5 is required for olfactory placode neurogenesis., Parlier D, Moers V, Van Campenhout C, Preillon J, Leclère L, Saulnier A, Sirakov M, Busengdal H, Kricha S, Marine JC, Rentzsch F, Bellefroid EJ., Dev Biol. January 1, 2013; 373 (1): 39-52.                              

Suv4-20h histone methyltransferases promote neuroectodermal differentiation by silencing the pluripotency-associated Oct-25 gene., Nicetto D, Hahn M, Jung J, Schneider TD, Straub T, David R, Schotta G, Rupp RA., PLoS Genet. January 1, 2013; 9 (1): e1003188.                                                                

AP-1(c-Jun/FosB) mediates xFoxD5b expression in Xenopus early developmental neurogenesis., Yoon J, Kim JH, Lee OJ, Lee SY, Lee SH, Park JB, Lee JY, Kim SC, Kim J., Int J Dev Biol. January 1, 2013; 57 (11-12): 865-72.        

Complex regulation controls Neurogenin3 proteolysis., Roark R, Itzhaki L, Philpott A., Biol Open. December 15, 2012; 1 (12): 1264-72.              

Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development., Xu Y, Xu Y, Xu C, Kato A, Tempel W, Abreu JG, Bian C, Hu Y, Hu D, Zhao B, Cerovina T, Diao J, Wu F, He HH, Cui Q, Clark E, Ma C, Barbara A, Veenstra GJ, Xu G, Kaiser UB, Liu XS, Sugrue SP, He X, Min J, Kato Y, Shi YG., Cell. December 7, 2012; 151 (6): 1200-13.                

Involvement of XZFP36L1, an RNA-binding protein, in Xenopus neural development., Xia YJ, Zhao SH, Mao BY., Dongwuxue Yanjiu. December 1, 2012; 33 (E5-6): E82-8.                

Transgenic analysis of signaling pathways required for Xenopus tadpole spinal cord and muscle regeneration., Lin G, Chen Y, Chen Y, Slack JM., Anat Rec (Hoboken). October 1, 2012; 295 (10): 1532-40.

Thyroid hormone signaling in the Xenopus laevis embryo is functional and susceptible to endocrine disruption., Fini JB, Le Mével S, Palmier K, Darras VM, Punzon I, Richardson SJ, Clerget-Froidevaux MS, Demeneix BA., Endocrinology. October 1, 2012; 153 (10): 5068-81.

Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation., Hindley C, Ali F, McDowell G, Cheng K, Jones A, Guillemot F, Philpott A., Development. May 1, 2012; 139 (10): 1718-23.      

Differential distribution of competence for panplacodal and neural crest induction to non-neural and neural ectoderm., Pieper M, Ahrens K, Rink E, Peter A, Schlosser G., Development. March 1, 2012; 139 (6): 1175-87.                    

Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus., Park BY, Hong CS, Weaver JR, Rosocha EM, Saint-Jeannet JP., Dev Biol. February 1, 2012; 362 (1): 65-75.                

Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells., Evans AL, Faial T, Gilchrist MJ, Down T, Vallier L, Pedersen RA, Wardle FC, Smith JC., PLoS One. January 1, 2012; 7 (3): e33346.              

Identification and characterization of ADAM41, a novel ADAM metalloproteinase in Xenopus., Xu G, Wei S, White JM, DeSimone DW., Int J Dev Biol. January 1, 2012; 56 (5): 333-9.          

pTransgenesis: a cross-species, modular transgenesis resource., Love NR, Thuret R, Chen Y, Ishibashi S, Sabherwal N, Paredes R, Alves-Silva J, Dorey K, Noble AM, Guille MJ, Sasai Y, Papalopulu N, Amaya E., Development. December 1, 2011; 138 (24): 5451-8.              

The homeobox leucine zipper gene Homez plays a role in Xenopus laevis neurogenesis., Ghimouz R, Bar I, Hanotel J, Minela B, Keruzore M, Thelie A, Bellefroid EJ., Biochem Biophys Res Commun. November 11, 2011; 415 (1): 11-6.            

Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis., Ali F, Hindley C, McDowell G, Deibler R, Jones A, Kirschner M, Guillemot F, Philpott A., Development. October 1, 2011; 138 (19): 4267-77.      

Over-expression of atf4 in Xenopus embryos interferes with neurogenesis and eye formation., Liu JT, Yang Y, Guo XG, Chen M, Ding HZ, Chen YL, Chen YL, Wang MR., Dongwuxue Yanjiu. October 1, 2011; 32 (5): 485-91.            

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